Aliskiren combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Loss Of Consciousness Other Serious Female 12/29/2008 Physician United Kingdom
Primary
Concomitant
Orthopnoea Other Serious 69 Male 1/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Lethargy Other Serious 6/12/2009 53 Male 220 lb 7/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 68 Male 1/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Other Serious 12/16/2009 Male 251 lb 1/8/2010 Physician Switzerland
Primary
Secondary
Hyponatraemia Other Serious 12/16/2009 Male 251 lb 1/22/2010 Physician Switzerland
Primary
Secondary
Vertigo Hospitalization 1/5/2010 Male 181 lb 2/15/2010 Physician Germany
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 2/6/2010 Male 231 lb 2/19/2010 Physician Romania
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/5/2010 Male 181 lb 2/22/2010 Physician Germany
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 2/6/2010 Male 231 lb 2/23/2010 Physician Romania
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/5/2010 Male 181 lb 2/26/2010 Physician Germany
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/5/2010 Male 181 lb 3/9/2010 Physician Germany
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 2/6/2010 Male 231 lb 3/19/2010 Physician Romania
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 2/6/2010 Male 231 lb 3/25/2010 Physician Romania
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/3/2010 49 Male 223 lb 5/26/2010 Physician Denmark
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/3/2010 49 Male 223 lb 6/4/2010 Physician Denmark
Primary
Secondary
Concomitant
Muscle Spasms Female 6/29/2010 Consumer United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 6/7/2010 Male 153 lb 7/13/2010 Physician Brazil
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 6/7/2010 60 Male 153 lb 7/20/2010 Physician Brazil
Primary
Secondary
Concomitant
Ischaemic Stroke Life Threatening 2/19/2010 51 Male 150 lb 8/4/2010 Physician Brazil
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/22/2010 79 Male 108 lb 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/22/2010 79 Male 108 lb 8/10/2010 Physician Japan
Primary
Secondary
Concomitant
Hyperkalaemia Life Threatening 2/19/2010 51 Male 150 lb 8/12/2010 Physician Brazil
Primary
Secondary
Concomitant
Disease Progression Hospitalization 7/1/2010 62 223 lb 8/12/2010 Physician Brazil
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 8/20/2010 24 Female 128 lb 8/27/2010 Physician India
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 8/20/2010 24 Female 128 lb 9/2/2010 Physician India
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/22/2010 79 Male 108 lb 9/8/2010 Physician Japan
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 8/20/2010 24 Female 128 lb 9/23/2010 Physician India
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/5/2010 77 Male 181 lb 9/30/2010 Physician Germany
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/22/2010 79 Male 108 lb 10/11/2010 Physician Japan
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 75 Male 10/19/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 9/27/2009 71 Male 194 lb 11/2/2010 Physician Germany
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 9/27/2009 71 Male 194 lb 11/12/2010 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/21/2010 69 Female 163 lb 11/30/2010 Physician Argentina
Primary
Secondary
Concomitant
Death Death 8/5/2010 57 Male 12/3/2010 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 6/22/2010 50 Male 136 lb 12/10/2010 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Renal Failure Other Serious 11/21/2010 69 Female 163 lb 12/10/2010 Physician Argentina
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 7/14/2010 56 Male 272 lb 12/10/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 11/21/2010 69 Female 163 lb 12/13/2010 Physician Argentina
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 8/20/2010 24 Female 128 lb 12/22/2010 Physician India
Primary
Secondary
Concomitant
Death Death 12/9/2010 48 Male 123 lb 12/24/2010 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 7/14/2010 56 Male 272 lb 1/3/2011 Physician United States
Primary
Secondary
Concomitant
Joint Swelling Hospitalization 7/22/2010 79 Male 108 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Cholelithiasis Other Serious 7/22/2010 79 Male 108 lb 1/18/2011 Physician Japan
Primary
Secondary
Concomitant
Arrhythmia Life Threatening 2/19/2010 51 Male 150 lb 1/20/2011 Physician Brazil
Primary
Secondary
Concomitant
Ankle Fracture Hospitalization 7/22/2010 79 Male 108 lb 1/25/2011 Physician Japan
Primary
Secondary
Concomitant
Atrial Flutter Hospitalization 7/14/2010 56 Male 272 lb 1/25/2011 Physician United States
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 7/22/2010 79 Male 108 lb 1/27/2011 Physician Japan
Primary
Secondary
Concomitant
Fatigue Other Serious 8/1/2010 60 Female 1/28/2011 Other Health Professional United States
Primary
Concomitant
Cough Hospitalization 6/22/2010 50 Male 136 lb 2/2/2011 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 12/25/2010 69 Female 150 lb 2/4/2011 Physician Lithuania
Primary
Secondary
Concomitant
Eyelid Oedema Other Serious 7/22/2010 79 Male 108 lb 2/4/2011 Physician Japan
Primary
Secondary
Concomitant
Catheterisation Cardiac Hospitalization 7/14/2010 56 Male 272 lb 2/7/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 7/1/2010 62 Male 223 lb 2/14/2011 Physician Brazil
Primary
Secondary
Concomitant
Resuscitation Other Serious 6/7/2010 60 Male 153 lb 2/16/2011 Physician Brazil
Primary
Secondary
Concomitant
Bone Atrophy Hospitalization 7/22/2010 79 Male 108 lb 2/18/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Potassium Increased Hospitalization 7/14/2010 56 Male 272 lb 2/21/2011 Physician United States
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 6/7/2010 60 Male 153 lb 2/25/2011 Physician Brazil
Primary
Secondary
Concomitant
Hernia Repair Other Serious 4/25/2010 75 Male 199 lb 3/7/2011 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/25/2010 75 Male 199 lb 3/10/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Blood Potassium Increased Hospitalization 7/14/2010 56 Male 272 lb 3/25/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 7/14/2010 56 Male 272 lb 4/15/2011 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/22/2011 78 Female 5/5/2011 Physician Colombia
Primary
Concomitant
Bone Atrophy Other Serious 7/22/2010 79 Male 108 lb 5/20/2011 Physician Japan
Primary
Secondary
Concomitant
Ocular Icterus Death 7/22/2010 79 Male 108 lb 5/23/2011 Physician Japan
Primary
Secondary
Concomitant
Bone Atrophy Hospitalization 7/22/2010 79 Male 108 lb 5/23/2011 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 3/22/2011 78 Female 5/23/2011 Physician Colombia
Primary
Concomitant
Hepatic Steatosis Other Serious 2/19/2009 67 Male 223 lb 6/30/2011 Physician Germany
Primary
Secondary
Concomitant
Musculoskeletal Pain Disability 7/22/2010 79 Male 108 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Ocular Icterus Disability 7/22/2010 79 Male 108 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 9/14/2010 78 Male 212 lb 7/6/2011 Physician Poland
Primary
Secondary
Concomitant
Death Death 2/19/2009 67 Male 223 lb 7/7/2011 Physician Germany
Primary
Secondary
Concomitant
Oedema Other Serious 6/14/2010 62 Male 7/8/2011 Physician Japan
Primary
Secondary
Concomitant
Constipation Hospitalization 7/22/2010 79 Male 108 lb 7/11/2011 Physician Japan
Primary
Secondary
Concomitant
Eyelid Oedema Death 7/22/2010 79 Male 108 lb 7/11/2011 Physician Japan
Primary
Secondary
Concomitant
Chest Pain Death 7/22/2010 79 Male 108 lb 7/11/2011 Physician Japan
Primary
Secondary
Concomitant
Concomitant Disease Progression Life Threatening 9/14/2010 78 Male 212 lb 7/13/2011 Physician Poland
Primary
Secondary
Concomitant
Hemiplegia Other Serious 2/1/2010 67 Male 223 lb 7/15/2011 Physician Germany
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 2/1/2010 67 Male 223 lb 7/29/2011 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/14/2010 62 Male 8/1/2011 Physician Japan
Primary
Secondary
Concomitant
Oedema Hospitalization 6/14/2010 62 Male 8/8/2011 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/21/2011 51 Female 150 lb 8/9/2011 Pharmacist Japan
Primary
Secondary
Liver Abscess Other Serious 4/18/2010 86 Male 168 lb 8/22/2011 Physician Italy
Primary
Secondary
Concomitant
Glycosylated Haemoglobin Increased Death 2/1/2010 67 Male 223 lb 9/12/2011 Physician Germany
Primary
Secondary
Concomitant
Blood Urea Increased Hospitalization 2/17/2011 64 Male 170 lb 9/3/2011 Physician Pakistan
Primary
Concomitant
Concomitant Disease Progression Life Threatening 7/14/2010 56 Male 272 lb 9/19/2011 Physician United States
Primary
Secondary
Concomitant
Hypertensive Crisis Hospitalization 8/12/2011 45 Male 10/4/2011 Physician Germany
Primary
Secondary
Concomitant
Concomitant Disease Progression Hospitalization 8/30/2011 54 Female 190 lb 10/13/2011 Physician Romania
Primary
Secondary
Concomitant
Brain Natriuretic Peptide Increased Other Serious 1/1/2004 62 Female 10/25/2011 Physician Brazil
Primary
Concomitant
Dyspnoea Other Serious 1/1/2002 62 Female 10/25/2011 Physician Brazil
Primary
Concomitant
Paralysis Other Serious 12/8/2010 91 Male 148 lb 10/26/2011 Physician Japan
Primary
Secondary
Concomitant
Concomitant Disease Progression Hospitalization 7/14/2010 56 Male 272 lb 10/26/2011 Physician United States
Primary
Secondary
Concomitant
Hypotension Other Serious 1/1/1990 62 Female 10/27/2011 Physician Brazil
Primary
Concomitant
Blood Urea Increased Hospitalization 2/17/2011 64 Male 170 lb 10/26/2011 Physician Pakistan
Primary
Concomitant
Renal Failure Hospitalization 10/28/2011 78 Male 298 lb 11/11/2011 Physician Italy
Primary
Secondary
Concomitant
Blood Pressure Systolic Increased Other Serious 12/8/2010 91 Male 148 lb 11/28/2011 Physician Japan
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 8/30/2011 54 Female 190 lb 12/6/2011 Physician Romania
Primary
Secondary
Concomitant
Lethargy Other Serious Female 101 lb 12/26/2011 Physician Netherlands
Primary
Concomitant
Oedema Hospitalization 6/14/2010 62 Male 12/28/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Pressure Decreased Other Serious 6/14/2010 62 Male 12/29/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Chronic Hospitalization 4/16/2011 51 Female 119 lb 12/30/2011 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Disease Progression Hospitalization 4/16/2011 51 Female 119 lb 12/30/2011 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Concomitant Disease Progression Other Serious 9/14/2010 78 Male 212 lb 1/10/2012 Consumer Poland
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 4/16/2011 51 Female 119 lb 1/17/2012 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Disease Progression Hospitalization 4/16/2011 51 Female 119 lb 1/17/2012 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Concomitant Disease Progression Hospitalization 4/16/2011 51 Female 124 lb 1/25/2012 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 7/7/2011 45 Male 1/26/2012 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/14/2010 78 Male 212 lb 1/27/2012 Physician Poland
Primary
Secondary
Concomitant
Bradyarrhythmia Hospitalization 9/14/2010 78 Male 212 lb 1/27/2012 Physician Poland
Primary
Secondary
Concomitant
Hypertensive Crisis Hospitalization 7/7/2011 45 Male 1/30/2012 Physician Germany
Primary
Secondary
Concomitant
Myocardial Infarction Death 1/12/2012 50 Male 237 lb 2/6/2012 Physician Ireland
Primary
Concomitant
Renal Impairment Hospitalization 4/16/2011 51 Female 124 lb 2/8/2012 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 4/16/2011 51 Female 124 lb 2/8/2012 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 12/1/2011 52 Female 153 lb 2/13/2012 Physician Brazil
Primary
Secondary
Concomitant
Blood Aldosterone Increased Other Serious 7/2/2010 59 Female 176 lb 2/14/2012 Consumer Germany
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 4/16/2011 51 Female 124 lb 2/29/2012 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 4/16/2011 51 Female 124 lb 2/29/2012 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Disease Progression Death 1/12/2012 50 Male 237 lb 3/5/2012 Physician Ireland
Primary
Concomitant
Atrial Fibrillation Hospitalization 4/16/2011 51 Female 124 lb 3/8/2012 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 4/16/2011 51 Female 124 lb 3/8/2012 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 4/7/2011 74 Female 231 lb 3/14/2012 Physician Germany
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 7/7/2011 45 Male 3/15/2012 Germany
Primary
Secondary
Concomitant
Renal Cell Carcinoma Hospitalization 2/21/2012 74 Male 228 lb 3/16/2012 Other Health Professional Austria
Primary
Concomitant
Cardiac Failure Hospitalization 7/1/2011 74 Male 228 lb 3/19/2012 Physician Austria
Primary
Concomitant
Pollakiuria Hospitalization 1/25/2011 82 Male 132 lb 3/28/2012 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Hospitalization 2/21/2012 74 Male 228 lb 4/2/2012 Other Health Professional Austria
Primary
Concomitant
Hyperkalaemia Hospitalization 7/7/2011 45 Male 4/5/2012 Physician Germany
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 1/24/2012 65 Male 205 lb 4/16/2012 Physician United States
Primary
Secondary
Concomitant
Disease Progression Death 1/12/2012 50 Male 237 lb 4/17/2012 Physician Ireland
Primary
Concomitant
Sudden Cardiac Death Death 2/10/2012 78 Male 193 lb 4/17/2012 Physician Poland
Primary
Concomitant
Ascites Other Serious 58 Male 4/19/2012 Other Health Professional Japan
Primary
Concomitant
Cardiovascular Event Prophylaxis Hospitalization 5/23/2011 68 Female 172 lb 4/20/2012 Physician Germany
Primary
Concomitant
Hyponatraemia Hospitalization 4/16/2011 51 Female 108 lb 5/10/2012 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Disease Progression Hospitalization 4/16/2011 51 Female 108 lb 5/10/2012 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 4/16/2011 51 Female 108 lb 5/11/2012 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/16/2011 51 Female 108 lb 5/11/2012 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 7/7/2011 45 Male 5/23/2012 Physician Germany
Primary
Secondary
Concomitant
Renal Cell Carcinoma Hospitalization 2/21/2012 74 Male 228 lb 6/6/2012 Other Health Professional Austria
Primary
Concomitant
Diarrhoea Hospitalization 10/27/2011 78 Male 298 lb 6/14/2012 Physician Italy
Primary
Secondary
Concomitant
Heat Illness Other Serious 7/23/2010 81 Male 132 lb 6/14/2012 Physician Japan
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 2/10/2012 78 Male 193 lb 7/10/2012 Physician Poland
Primary
Concomitant
Acute Pulmonary Oedema Death 5/24/2012 71 Female 7/13/2012 Physician Peru
Primary
Concomitant
Acute Pulmonary Oedema Hospitalization 5/24/2012 71 Female 7/26/2012 Physician Peru
Primary
Concomitant
Cardiogenic Shock Hospitalization 12/1/2011 53 Female 153 lb 8/30/2012 Other Health Professional Br
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 10/13/2011 47 Female 242 lb 10/3/2012 Physician Us
Primary
Secondary
Concomitant
Cardiogenic Shock Death 9/26/2012 79 Female 82 lb 11/10/2012 Other Health Professional Br
Primary
Concomitant
Renal Disorder Other Serious 9/7/2010 82 Female 112 lb 8/28/2013 Other Health Professional Br
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 11/24/2012 76 Male 201 lb 3/6/2013 Other Health Professional Au
Primary
Concomitant
Sudden Cardiac Death Death 5/17/2013 54 Female 154 lb 6/12/2013 Other Health Professional Us
Primary
Concomitant
Carotid Artery Stenosis Hospitalization 7/7/2011 46 Male 4/19/2013 Physician De
Primary
Secondary
Concomitant

Drug Data