Aliskiren combined with Lasix

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Other Serious 1/1/2006 57 Female 195 lb 5/1/2009 Consumer Canada
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 7/1/2009 64 Female 10/1/2009 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 7/1/2009 64 Female 10/8/2009 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 7/1/2009 64 Female 10/14/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 11/19/2009 Male 194 lb 12/3/2009 Physician Japan
Primary
Secondary
Concomitant
Scar Hospitalization 11/19/2009 Male 194 lb 12/11/2009 Physician Japan
Primary
Secondary
Concomitant
Scar Hospitalization 11/19/2009 Male 194 lb 12/23/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 12/26/2009 Male 262 lb 2/16/2010 Physician United States
Primary
Secondary
Concomitant
Scar Other Serious 11/19/2009 Male 194 lb 3/15/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 12/26/2009 66 Male 262 lb 4/1/2010 Physician United States
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 3/3/2010 47 Male 132 lb 4/8/2010 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 3/3/2010 47 Male 132 lb 5/17/2010 Physician Japan
Primary
Secondary
Concomitant
Scar Other Serious 11/19/2009 72 Male 194 lb 5/20/2010 Physician Japan
Primary
Secondary
Concomitant
Restless Legs Syndrome Other Serious 11/11/2009 72 Female 173 lb 6/4/2010 Physician United States
Primary
Secondary
Concomitant
Coronary Artery Restenosis Other Serious 6/1/2010 74 Male 115 lb 6/10/2010 Physician Japan
Primary
Secondary
Concomitant
Restless Legs Syndrome Other Serious 11/1/2009 72 Female 174 lb 6/10/2010 Physician
Primary
Secondary
Concomitant
Restless Legs Syndrome Other Serious 11/11/2009 72 Female 174 lb 6/11/2010 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 6/14/2010 62 Male 6/22/2010 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 1/6/2010 47 Male 132 lb 6/24/2010 Physician Japan
Primary
Secondary
Concomitant
Coronary Artery Restenosis Other Serious 6/1/2010 74 Male 115 lb 6/25/2010 Physician Japan
Primary
Secondary
Concomitant
Oedema Other Serious 6/14/2010 62 Male 7/13/2010 Physician Japan
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 7/6/2010 72 Male 7/16/2010 Physician Netherlands
Primary
Secondary
Concomitant
Scar Other Serious 11/19/2009 72 Male 194 lb 7/23/2010 Physician Japan
Primary
Secondary
Concomitant
Oedema Other Serious 6/14/2010 62 Male 7/23/2010 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 1/6/2010 47 Male 132 lb 7/26/2010 Physician Japan
Primary
Secondary
Concomitant
Drug Ineffective Male 276 lb 7/31/2010 Other Health Professional United States
Primary
Concomitant
Dyspnoea Hospitalization 7/6/2010 72 Male 7/30/2010 Physician Netherlands
Primary
Secondary
Concomitant
Scar Other Serious 11/19/2009 72 Male 194 lb 8/11/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 11/19/2009 72 Male 194 lb 8/12/2010 Physician Japan
Primary
Secondary
Concomitant
Oedema Other Serious 6/14/2010 62 Male 8/20/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/9/2010 49 Male 152 lb 8/26/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 11/19/2009 72 Male 194 lb 8/26/2010 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 7/1/2009 64 Female 9/16/2010 United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 9/21/2010 76 Female 10/8/2010 Physician Italy
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 3/9/2010 49 Male 152 lb 10/11/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/1/2010 Female 150 lb 10/25/2010 Pharmacist France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/1/2010 Female 150 lb 10/27/2010 Pharmacist France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 3/9/2010 49 Male 152 lb 11/8/2010 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 1/6/2010 47 Male 132 lb 11/12/2010 Physician Japan
Primary
Secondary
Concomitant
Restless Legs Syndrome Other Serious 11/1/2009 72 Female 174 lb 12/6/2010 Physician
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 7/1/2009 64 Female 10/1/2009 United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 4/29/2010 86 Female 110 lb 12/30/2010 Physician Japan
Primary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious 10/21/2010 58 Male 1/4/2011 Physician Slovenia
Primary
Concomitant
Nocturnal Dyspnoea Hospitalization 3/9/2010 49 Male 152 lb 2/1/2011 Physician Japan
Primary
Secondary
Concomitant
Dyspnoea Other Serious 12/1/2010 62 Male 2/2/2011 Physician Japan
Primary
Secondary
Concomitant
Catheterisation Cardiac Hospitalization 7/14/2010 56 Male 272 lb 2/7/2011 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 3/9/2010 49 Male 152 lb 2/9/2011 Physician Japan
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 1/28/2011 78 Male 132 lb 2/9/2011 Physician Japan
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 8/17/2010 56 Female 1/5/2011 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Decreased Hospitalization 1/28/2011 78 Male 132 lb 2/18/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Potassium Increased Hospitalization 7/14/2010 56 Male 272 lb 2/21/2011 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/28/2011 78 Male 132 lb 3/3/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 12/1/2010 62 Male 3/4/2011 Physician Japan
Primary
Secondary
Concomitant
Deafness Disability 1/31/2011 Female 223 lb 3/11/2011 Physician United States
Primary
Concomitant
Cardiac Failure Hospitalization 2/1/2011 3/14/2011 Physician Japan
Primary
Secondary
Concomitant
Asthenia Other Serious 1/28/2011 78 Male 132 lb 3/14/2011 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/28/2011 78 Male 132 lb 3/25/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Potassium Increased Hospitalization 7/14/2010 56 Male 272 lb 3/25/2011 Physician United States
Primary
Secondary
Concomitant
Atrial Flutter Hospitalization 2/1/2011 3/25/2011 Physician Japan
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/28/2011 78 Male 132 lb 4/5/2011 Physician Japan
Primary
Secondary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious 10/21/2010 58 Male 4/8/2011 Physician Slovenia
Primary
Concomitant
Myocardial Ischaemia Hospitalization 6/14/2010 62 Male 4/15/2011 Physician Japan
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 7/14/2010 56 Male 272 lb 4/15/2011 Physician United States
Primary
Secondary
Concomitant
Chest Discomfort Hospitalization 12/1/2010 62 Male 4/15/2011 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 2/1/2011 4/17/2011 Physician Japan
Primary
Secondary
Concomitant
Cholangitis Other Serious 1/28/2011 78 Male 132 lb 4/18/2011 Physician Japan
Primary
Secondary
Concomitant
Chest Discomfort Hospitalization 12/1/2010 62 Male 4/20/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 2/8/2011 48 Male 234 lb 4/22/2011 Physician Japan
Primary
Secondary
Concomitant
Asthenia Hospitalization 1/28/2011 78 Male 132 lb 5/9/2011 Physician Japan
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Hospitalization 12/1/2010 62 Male 5/16/2011 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 12/1/2010 62 Male 5/18/2011 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 4/4/2011 63 Male 159 lb 5/27/2011 Physician Japan
Primary
Secondary
Concomitant
Gastric Cancer Other Serious 6/2/2011 Physician Canada
Primary
Concomitant
Cardiac Failure Hospitalization 4/4/2011 63 Male 159 lb 6/3/2011 Physician Japan
Primary
Secondary
Concomitant
Chest Discomfort Other Serious 12/1/2010 62 Male 6/6/2011 Physician Japan
Primary
Secondary
Concomitant
Ascites Other Serious Male 6/8/2011 Physician Japan
Primary
Concomitant
Pulmonary Congestion Hospitalization 6/11/2011 69 Male 163 lb 6/27/2011 Physician Japan
Primary
Secondary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious Female 6/29/2011 Physician Canada
Primary
Concomitant
Renal Failure Disability 2/8/2011 48 Male 234 lb 6/30/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 7/6/2011 Physician Japan
Primary
Secondary
Concomitant
Oedema Other Serious 6/14/2010 62 Male 7/8/2011 Physician Japan
Primary
Secondary
Concomitant
Asthenia Hospitalization 1/28/2011 78 Male 132 lb 6/24/2011 Physician Japan
Primary
Secondary
Concomitant
Fluid Overload Hospitalization 6/11/2011 69 Male 163 lb 7/19/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 6/1/2011 58 Female 7/22/2011 Other Health Professional France
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/28/2011 78 Male 132 lb 7/27/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/14/2010 62 Male 8/1/2011 Physician Japan
Primary
Secondary
Concomitant
Oedema Hospitalization 6/14/2010 62 Male 8/8/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 8/10/2011 Physician Japan
Primary
Secondary
Concomitant
Cerebellar Haemorrhage Hospitalization 6/18/2011 61 Male 128 lb 8/11/2011 Physician Japan
Primary
Secondary
Concomitant
Oesophageal Carcinoma Hospitalization 7/28/2011 81 Male 104 lb 8/12/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 3/12/2010 47 Male 8/15/2011 Physician Japan
Primary
Concomitant
Cerebellar Haemorrhage Hospitalization 6/18/2011 61 Male 128 lb 8/24/2011 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/20/2011 79 Male 134 lb 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Bacterial Test Positive Hospitalization 8/20/2011 79 Male 134 lb 9/13/2011 Physician Japan
Primary
Secondary
Concomitant
Sudden Death Death 9/1/2011 66 Male 139 lb 9/14/2011 Physician Japan
Primary
Secondary
Concomitant
Concomitant Disease Progression Life Threatening 7/14/2010 56 Male 272 lb 9/19/2011 Physician United States
Primary
Secondary
Concomitant
Condition Aggravated Death 9/1/2011 66 Male 139 lb 9/22/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 9/28/2011 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/20/2011 79 Male 134 lb 9/30/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 3/12/2010 47 Male 10/4/2011 Physician Japan
Primary
Concomitant
Duodenal Neoplasm Hospitalization 8/23/2011 70 Female 179 lb 10/5/2011 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 10/6/2011 Physician Japan
Primary
Secondary
Concomitant
Eosinophilic Oesophagitis Hospitalization 7/28/2011 81 Male 104 lb 10/12/2011 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/20/2011 79 Male 134 lb 10/12/2011 Physician Japan
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 9/28/2011 76 Male 139 lb 10/13/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 10/1/2011 82 Male 130 lb 10/17/2011 Physician Japan
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 9/28/2011 76 Male 139 lb 10/20/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 10/1/2011 82 Male 130 lb 10/21/2011 Physician Japan
Primary
Secondary
Concomitant
Sudden Cardiac Death Hospitalization 8/29/2011 60 Male 146 lb 10/25/2011 Physician Japan
Primary
Secondary
Concomitant
Concomitant Disease Progression Hospitalization 7/14/2010 56 Male 272 lb 10/26/2011 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/20/2011 79 Male 134 lb 11/2/2011 Physician Japan
Primary
Secondary
Concomitant
Ventricular Extrasystoles Death 8/29/2011 60 Male 146 lb 11/8/2011 Physician Japan
Primary
Secondary
Concomitant
Pelvic Mass Hospitalization 8/23/2011 70 Female 179 lb 11/15/2011 Physician United States
Primary
Concomitant
Condition Aggravated Hospitalization 8/29/2011 60 Male 146 lb 11/15/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 11/18/2011 Physician Japan
Primary
Secondary
Concomitant
Gastroenteritis Other Serious 3/11/2011 82 Male 130 lb 11/25/2011 Physician Japan
Primary
Secondary
Concomitant
Impaired Gastric Emptying Hospitalization 10/3/2011 66 Male 265 lb 11/28/2011 Physician United States
Primary
Concomitant
Dehydration Death 7/14/2010 84 Female 106 lb 12/2/2011 Physician Japan
Primary
Concomitant
Pulmonary Congestion Hospitalization 6/11/2011 69 Male 163 lb 12/12/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Pressure Diastolic Decreased Other Serious 10/4/2011 86 12/14/2011 Physician Canada
Primary
Concomitant
Gastritis Atrophic Other Serious 3/11/2011 82 Male 130 lb 12/16/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Congestion Hospitalization 6/11/2011 69 Male 163 lb 12/26/2011 Physician Japan
Primary
Secondary
Concomitant
Oedema Hospitalization 6/14/2010 62 Male 12/28/2011 Physician Japan
Primary
Secondary
Concomitant
Gastritis Atrophic Other Serious 3/11/2011 82 Male 130 lb 12/29/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Pressure Decreased Other Serious 6/14/2010 62 Male 12/29/2011 Physician Japan
Primary
Secondary
Concomitant
Eosinophilic Oesophagitis Hospitalization 7/28/2011 81 Male 104 lb 1/5/2012 Physician Japan
Primary
Concomitant
Influenza Like Illness Life Threatening 1/20/2011 58 Male 205 lb 1/18/2012 Physician Germany
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 6/16/2010 77 Female 128 lb 2/1/2012 Physician Japan
Primary
Concomitant
Interacting
Glycosylated Haemoglobin Increased Other Serious 8/11/2011 75 Male 2/2/2012 Physician France
Primary
Concomitant
Metastases To Central Nervous System Death 8/11/2011 68 Male 203 lb 2/2/2012 Physician France
Primary
Concomitant
Cardiac Failure Congestive Other Serious 12/1/2010 62 Male 2/3/2012 Physician Japan
Primary
Secondary
Concomitant
Arrhythmia Other Serious Male 2/10/2012 Physician Canada
Primary
Concomitant
Asthma Hospitalization 2/2/2012 81 Male 2/14/2012 Physician Japan
Primary
Secondary
Cardio-respiratory Arrest Hospitalization 2/2/2012 81 Male 2/14/2012 Physician Japan
Primary
Secondary
Subarachnoid Haemorrhage Death 1/31/2012 78 Female 110 lb 2/21/2012 Physician India
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Death 1/31/2012 78 Female 110 lb 2/24/2012 Physician India
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 8/23/2011 70 Female 179 lb 2/27/2012 Other Health Professional United States
Primary
Concomitant
Hyponatraemia Hospitalization 86 Female 3/7/2012 Other Health Professional France
Primary
Concomitant
Obstruction Death 8/23/2011 70 Female 179 lb 3/8/2012 Physician United States
Primary
Concomitant
Arteriosclerosis Coronary Artery Hospitalization 10/1/2011 60 Female 123 lb 3/9/2012 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 6/16/2010 77 Female 128 lb 3/20/2012 Physician Japan
Primary
Concomitant
Interacting
Renal Cell Carcinoma Hospitalization 10/1/2011 60 Female 123 lb 4/2/2012 Physician Japan
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 12/8/2011 79 Female 90 lb 4/9/2012 Physician Japan
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 2/11/2012 74 Male 4/10/2012 Other Health Professional France
Primary
Secondary
Asthma Hospitalization 2/2/2012 81 Male 4/11/2012 Physician Japan
Primary
Secondary
Cerebral Infarction Hospitalization 2/2/2012 81 Male 4/11/2012 Physician Japan
Primary
Secondary
Alanine Aminotransferase Increased Hospitalization 2/7/2012 64 Male 130 lb 4/12/2012 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Bullous Other Serious 11/27/2010 88 Male 4/16/2012 Other Health Professional France
Primary
Secondary
Concomitant
Colon Adenoma Hospitalization 3/21/2012 64 Male 141 lb 4/18/2012 Physician Japan
Primary
Secondary
Concomitant
Contusion Hospitalization 3/11/2012 83 Female 4/19/2012 Physician Japan
Primary
Concomitant

Drug Data