Aliskiren combined with Carvedilol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pruritus Male 210 lb 8/29/2008 United States
Primary
Secondary
Concomitant
Hepatitis Cholestatic Hospitalization 11/19/2008 63 Female 3/2/2009 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Hepatitis Cholestatic Hospitalization 11/19/2008 63 Female 2/28/2009 Physician Switzerland
Primary
Secondary
Concomitant
Hepatitis Cholestatic Hospitalization 11/19/2008 63 Female 3/5/2009 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Mean Cell Volume Decreased Hospitalization 9/8/2008 Female 110 lb 9/16/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pruritus 66 Male 211 lb 11/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 11/2/2009 65 Male 146 lb 1/5/2010 Japan
Primary
Secondary
Concomitant
Mean Cell Volume Decreased Hospitalization 9/8/2008 Female 110 lb 2/18/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 2/6/2010 Male 231 lb 2/19/2010 Physician Romania
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 2/6/2010 Male 231 lb 2/23/2010 Physician Romania
Primary
Secondary
Concomitant
Vomiting Other Serious 2/10/2009 Female 3/2/2010 Physician
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 2/6/2010 Male 231 lb 3/19/2010 Physician Romania
Primary
Secondary
Concomitant
Weight Increased Hospitalization 3/2/2010 Male 195 lb 3/23/2010 Physician Argentina
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 2/6/2010 Male 231 lb 3/25/2010 Physician Romania
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 3/3/2010 47 Male 132 lb 4/8/2010 Physician Japan
Primary
Secondary
Concomitant
Vertigo Hospitalization 3/26/2010 79 Male 179 lb 4/16/2010 Physician Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Vertigo Hospitalization 3/26/2010 79 Male 179 lb 5/6/2010 Physician Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Muscle Spasms Female 6/29/2010 Consumer United States
Primary
Secondary
Concomitant
Ischaemic Stroke Life Threatening 2/19/2010 51 Male 150 lb 8/4/2010 Physician Brazil
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/22/2010 79 Male 108 lb 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/22/2010 79 Male 108 lb 8/10/2010 Physician Japan
Primary
Secondary
Concomitant
Hyperkalaemia Life Threatening 2/19/2010 51 Male 150 lb 8/12/2010 Physician Brazil
Primary
Secondary
Concomitant
Disease Progression Hospitalization 7/1/2010 62 223 lb 8/12/2010 Physician Brazil
Primary
Secondary
Concomitant
Weight Increased Hospitalization 3/2/2010 82 Male 195 lb 8/31/2010 Physician Argentina
Primary
Secondary
Concomitant
Dysfunctional Uterine Bleeding Other Serious 4/28/2010 24 Female 84 lb 9/8/2010 Physician India
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/22/2010 79 Male 108 lb 9/8/2010 Physician Japan
Primary
Secondary
Concomitant
Vertigo Other Serious 9/3/2010 70 Male 190 lb 9/15/2010 Physician Sweden
Primary
Secondary
Concomitant
Weight Increased Hospitalization 3/2/2010 82 Male 195 lb 9/17/2010 Physician Argentina
Primary
Secondary
Concomitant
Dysfunctional Uterine Bleeding Other Serious 4/28/2010 24 Female 84 lb 9/20/2010 Physician India
Primary
Secondary
Concomitant
Dysfunctional Uterine Bleeding Other Serious 4/28/2010 24 Female 84 lb 9/23/2010 Physician India
Primary
Secondary
Concomitant
Weight Increased Hospitalization 3/2/2010 82 Male 195 lb 9/27/2010 Physician Argentina
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/5/2010 77 Male 181 lb 9/30/2010 Physician Germany
Primary
Secondary
Concomitant
Mitral Valve Incompetence Hospitalization 8/1/2010 74 Female 165 lb 10/5/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/22/2010 79 Male 108 lb 10/11/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 58 Male 201 lb 10/14/2010 Other Health Professional Brazil
Primary
Secondary
Renal Failure Hospitalization 11/21/2010 69 Female 163 lb 11/30/2010 Physician Argentina
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 6/22/2010 50 Male 136 lb 12/10/2010 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Renal Failure Other Serious 11/21/2010 69 Female 163 lb 12/10/2010 Physician Argentina
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 7/14/2010 56 Male 272 lb 12/10/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 11/21/2010 69 Female 163 lb 12/13/2010 Physician Argentina
Primary
Secondary
Concomitant
Death Death 12/9/2010 48 Male 123 lb 12/24/2010 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 7/14/2010 56 Male 272 lb 1/3/2011 Physician United States
Primary
Secondary
Concomitant
Joint Swelling Hospitalization 7/22/2010 79 Male 108 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Cholelithiasis Other Serious 7/22/2010 79 Male 108 lb 1/18/2011 Physician Japan
Primary
Secondary
Concomitant
Arrhythmia Life Threatening 2/19/2010 51 Male 150 lb 1/20/2011 Physician Brazil
Primary
Secondary
Concomitant
Ankle Fracture Hospitalization 7/22/2010 79 Male 108 lb 1/25/2011 Physician Japan
Primary
Secondary
Concomitant
Atrial Flutter Hospitalization 7/14/2010 56 Male 272 lb 1/25/2011 Physician United States
Primary
Secondary
Concomitant
Colonic Polyp Hospitalization 12/7/2010 75 Male 139 lb 1/26/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 1/10/2011 70 Female 190 lb 1/26/2011 Physician Italy
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 7/22/2010 79 Male 108 lb 1/27/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/25/2010 82 Male 283 lb 1/28/2011 Physician
Primary
Concomitant
Bile Duct Obstruction Hospitalization 12/12/2010 53 Female 170 lb 2/1/2011 Physician Argentina
Primary
Secondary
Concomitant
Cough Hospitalization 6/22/2010 50 Male 136 lb 2/2/2011 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Influenza Like Illness Life Threatening 1/20/2011 58 Male 205 lb 2/4/2011 Physician Germany
Primary
Secondary
Eyelid Oedema Other Serious 7/22/2010 79 Male 108 lb 2/4/2011 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 3/2/2010 82 Male 195 lb 2/4/2011 Physician Argentina
Primary
Secondary
Concomitant
Catheterisation Cardiac Hospitalization 7/14/2010 56 Male 272 lb 2/7/2011 Physician United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 1/10/2011 70 Female 190 lb 2/9/2011 Physician Italy
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 7/1/2010 62 Male 223 lb 2/14/2011 Physician Brazil
Primary
Secondary
Concomitant
Concomitant Disease Progression Hospitalization 12/12/2010 53 Female 170 lb 2/15/2011 Physician Argentina
Primary
Secondary
Concomitant
Bone Atrophy Hospitalization 7/22/2010 79 Male 108 lb 2/18/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Potassium Increased Hospitalization 7/14/2010 56 Male 272 lb 2/21/2011 Physician United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death Male 185 lb 3/4/2011 Physician Brazil
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 6/1/2009 67 Female 3/23/2011 Consumer Germany
Primary
Secondary
Concomitant
Blood Potassium Increased Hospitalization 7/14/2010 56 Male 272 lb 3/25/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 7/14/2010 56 Male 272 lb 4/15/2011 Physician United States
Primary
Secondary
Concomitant
Bronchitis Hospitalization 2/3/2011 75 Female 159 lb 5/5/2011 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/22/2011 78 Female 5/5/2011 Physician Colombia
Primary
Concomitant
Cardio-respiratory Arrest Hospitalization 12/1/2010 62 Male 5/16/2011 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 12/1/2010 62 Male 5/18/2011 Physician Japan
Primary
Secondary
Concomitant
Abdominal Pain Upper Female 200 lb 5/19/2011 Consumer United States
Primary
Concomitant
Bone Atrophy Other Serious 7/22/2010 79 Male 108 lb 5/20/2011 Physician Japan
Primary
Secondary
Concomitant
Ocular Icterus Death 7/22/2010 79 Male 108 lb 5/23/2011 Physician Japan
Primary
Secondary
Concomitant
Bone Atrophy Hospitalization 7/22/2010 79 Male 108 lb 5/23/2011 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 3/22/2011 78 Female 5/23/2011 Physician Colombia
Primary
Concomitant
Ventricular Tachycardia Hospitalization 4/4/2011 63 Male 159 lb 5/27/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 4/4/2011 63 Male 159 lb 6/3/2011 Physician Japan
Primary
Secondary
Concomitant
Chest Discomfort Other Serious 12/1/2010 62 Male 6/6/2011 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Female 200 lb 6/6/2011 Consumer United States
Primary
Concomitant
Ascites Other Serious Male 6/8/2011 Physician Japan
Primary
Concomitant
Brain Stem Infarction Hospitalization 5/10/2010 49 Male 141 lb 6/8/2011 Physician Japan
Primary
Concomitant
Blood Pressure Fluctuation Other Serious Male 154 lb 6/9/2011 Physician Japan
Primary
Concomitant
Atrioventricular Block Hospitalization 4/19/2010 72 Male 123 lb 6/10/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Congestion Hospitalization 6/11/2011 69 Male 163 lb 6/27/2011 Physician Japan
Primary
Secondary
Concomitant
Syncope Other Serious 5/21/2011 91 Male 218 lb 6/29/2011 Physician Ireland
Primary
Secondary
Concomitant
Musculoskeletal Pain Disability 7/22/2010 79 Male 108 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Ocular Icterus Disability 7/22/2010 79 Male 108 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 9/14/2010 78 Male 212 lb 7/6/2011 Physician Poland
Primary
Secondary
Concomitant
Bronchitis Hospitalization 2/3/2011 75 Female 159 lb 7/6/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 7/6/2011 Physician Japan
Primary
Secondary
Concomitant
Oedema Other Serious 6/14/2010 62 Male 7/8/2011 Physician Japan
Primary
Secondary
Concomitant
Constipation Hospitalization 7/22/2010 79 Male 108 lb 7/11/2011 Physician Japan
Primary
Secondary
Concomitant
Eyelid Oedema Death 7/22/2010 79 Male 108 lb 7/11/2011 Physician Japan
Primary
Secondary
Concomitant
Chest Pain Death 7/22/2010 79 Male 108 lb 7/11/2011 Physician Japan
Primary
Secondary
Concomitant
Musculoskeletal Pain Disability 7/22/2010 79 Male 108 lb 7/12/2011 Physician Japan
Primary
Secondary
Concomitant
Concomitant Disease Progression Life Threatening 9/14/2010 78 Male 212 lb 7/13/2011 Physician Poland
Primary
Secondary
Concomitant
Asthenia Hospitalization 1/28/2011 78 Male 132 lb 6/24/2011 Physician Japan
Primary
Secondary
Concomitant
Fluid Overload Hospitalization 6/11/2011 69 Male 163 lb 7/19/2011 Physician Japan
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/28/2011 78 Male 132 lb 7/27/2011 Physician Japan
Primary
Secondary
Concomitant
Heart Rate Decreased Other Serious Male 7/29/2011 Physician Germany
Primary
Secondary
Angina Pectoris Other Serious Male 7/29/2011 Physician Germany
Primary
Secondary
Renal Failure Other Serious 6/14/2010 62 Male 8/1/2011 Physician Japan
Primary
Secondary
Concomitant
Oedema Hospitalization 6/14/2010 62 Male 8/8/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 8/10/2011 Physician Japan
Primary
Secondary
Concomitant
Cerebellar Haemorrhage Hospitalization 6/18/2011 61 Male 128 lb 8/11/2011 Physician Japan
Primary
Secondary
Concomitant
Oesophageal Carcinoma Hospitalization 7/28/2011 81 Male 104 lb 8/12/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 3/12/2010 47 Male 8/15/2011 Physician Japan
Primary
Concomitant
Renal Failure Chronic Other Serious Male 154 lb 8/15/2011 Physician Japan
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization 7/15/2011 72 Male 8/16/2011 Physician Japan
Primary
Concomitant
Cerebellar Haemorrhage Hospitalization 6/18/2011 61 Male 128 lb 8/24/2011 Physician Japan
Primary
Secondary
Concomitant
Concomitant Disease Progression Life Threatening 8/9/2011 65 Female 191 lb 9/6/2011 Physician Argentina
Primary
Concomitant
Decreased Appetite Hospitalization 8/12/2011 72 Male 169 lb 9/6/2011 Other Health Professional Japan
Primary
Concomitant
Concomitant Disease Progression Life Threatening 7/14/2010 56 Male 272 lb 9/19/2011 Physician United States
Primary
Secondary
Concomitant
Small Cell Lung Cancer Stage Unspecified Hospitalization 8/11/2011 72 Male 9/19/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Hospitalization 9/4/2011 59 Male 163 lb 9/20/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 9/4/2011 59 Male 163 lb 9/22/2011 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 8/12/2011 72 Male 169 lb 9/15/2011 Japan
Primary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 9/28/2011 Physician Japan
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 9/4/2011 59 Male 163 lb 9/30/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 3/12/2010 47 Male 10/4/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 10/6/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious Male 154 lb 10/7/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 5/23/2011 85 Male 121 lb 10/10/2011 Physician Japan
Primary
Concomitant
Eosinophilic Oesophagitis Hospitalization 7/28/2011 81 Male 104 lb 10/12/2011 Physician Japan
Primary
Concomitant
Muscular Weakness Hospitalization 9/28/2011 76 Male 139 lb 10/13/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 10/1/2011 82 Male 130 lb 10/17/2011 Physician Japan
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 9/28/2011 76 Male 139 lb 10/20/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 10/1/2011 82 Male 130 lb 10/21/2011 Physician Japan
Primary
Secondary
Concomitant
Brain Natriuretic Peptide Increased Other Serious 1/1/2004 62 Female 10/25/2011 Physician Brazil
Primary
Concomitant
Dyspnoea Other Serious 1/1/2002 62 Female 10/25/2011 Physician Brazil
Primary
Concomitant
Sudden Cardiac Death Hospitalization 8/29/2011 60 Male 146 lb 10/25/2011 Physician Japan
Primary
Secondary
Concomitant
Paralysis Other Serious 12/8/2010 91 Male 148 lb 10/26/2011 Physician Japan
Primary
Secondary
Concomitant
Concomitant Disease Progression Hospitalization 7/14/2010 56 Male 272 lb 10/26/2011 Physician United States
Primary
Secondary
Concomitant
Hypotension Other Serious 1/1/1990 62 Female 10/27/2011 Physician Brazil
Primary
Concomitant
Hyperhidrosis Hospitalization 8/12/2011 72 Male 169 lb 10/25/2011 Other Health Professional Japan
Primary
Concomitant
Ventricular Extrasystoles Death 8/29/2011 60 Male 146 lb 11/8/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Pressure Diastolic Decreased Other Serious 10/1/2010 59 Male 108 lb 11/15/2011 Physician Japan
Primary
Concomitant
Condition Aggravated Hospitalization 8/29/2011 60 Male 146 lb 11/15/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 11/18/2011 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Death Male 121 lb 11/22/2011 Physician Japan
Primary
Secondary
Concomitant
Gastroenteritis Other Serious 3/11/2011 82 Male 130 lb 11/25/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Pressure Systolic Increased Other Serious 12/8/2010 91 Male 148 lb 11/28/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Congestion Hospitalization 6/11/2011 69 Male 163 lb 12/12/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/1/2009 67 Female 12/8/2011 Physician Germany
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 6/1/2009 67 Female 12/14/2011 Physician Germany
Primary
Secondary
Concomitant
Gastritis Atrophic Other Serious 3/11/2011 82 Male 130 lb 12/16/2011 Physician Japan
Primary
Secondary
Concomitant
Bradycardia Hospitalization 12/10/2011 79 Male 123 lb 12/22/2011 Physician Japan
Primary
Concomitant
Pulmonary Congestion Hospitalization 6/11/2011 69 Male 163 lb 12/26/2011 Physician Japan
Primary
Secondary
Concomitant
Oedema Hospitalization 6/14/2010 62 Male 12/28/2011 Physician Japan
Primary
Secondary
Concomitant
Gastritis Atrophic Other Serious 3/11/2011 82 Male 130 lb 12/29/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data