Alimta combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wound Debridement Other Serious 5/23/2005 55 Female 2/2/2006 United States
Primary
Concomitant
Skin Exfoliation Hospitalization 12/1/2005 62 Male 1/30/2006 Physician United States
Primary
Concomitant
Tremor Other Serious 12/1/2005 71 Female 5/1/2006 Physician United States
Primary
Secondary
Tremor Other Serious 12/1/2005 71 Female 5/2/2006 Physician United States
Primary
Secondary
Wound Debridement Other Serious 1/1/2004 55 Female 5/11/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 12/1/2005 71 Female 5/11/2006 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/6/2006 59 Male 6/16/2006 United States
Primary
Concomitant
Swelling Other Serious 5/27/2006 59 Male 7/28/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 9/1/2004 76 Male 8/4/2006 Other Health Professional United States
Primary
Concomitant
Renal Tubular Acidosis Other Serious 8/1/2005 53 Female 11/7/2006 Physician United States
Primary
Concomitant
Renal Cyst Other Serious 1/18/2005 83 Female 8/28/2006 Other Health Professional United States
Primary
Concomitant
Renal Cyst Other Serious 1/18/2005 83 Female 8/29/2006 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 9/15/2006 56 Male 280 lb 2/8/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 9/15/2006 56 Male 280 lb 2/12/2007 Physician United States
Primary
Concomitant
Somnolence Hospitalization 1/5/2007 59 Male 119 lb 3/18/2007 France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/5/2007 59 Male 119 lb 3/26/2007 Physician France
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/2006 59 124 lb 4/5/2007 Physician United States
Primary
Concomitant
X-ray Abnormal Other Serious 9/1/2006 59 Female 124 lb 4/18/2007 United States
Primary
Concomitant
Toothache Other Serious 5/9/2007 56 Male 186 lb 5/17/2007 Other Health Professional United States
Primary
Concomitant
Pulmonary Hypertension Other Serious Female 5/18/2007 Physician United States
Primary
Concomitant
Lacrimation Increased 1/1/2006 Male 2/16/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 56 Male 6/25/2007 Physician Germany
Primary
Secondary
Concomitant
Stomatitis Other Serious 4/15/2007 77 Male 178 lb 7/26/2007 Physician United States
Primary
Concomitant
Stomatitis Other Serious 4/15/2007 77 Male 178 lb 8/2/2007 Physician United States
Primary
Concomitant
Osteonecrosis Disability 12/6/2006 67 Male 11/8/2007
Primary
Secondary
Osteonecrosis Disability 12/6/2006 Male 11/12/2007 Physician France
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2004 67 Male 11/28/2007 France
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/4/2007 Female 116 lb 11/21/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/1/2007 58 Female 1/29/2008 Consumer United States
Primary
Concomitant
Osteonecrosis Disability 12/6/2006 67 Male 2/19/2008
Primary
Secondary
Pain In Jaw Other Serious 1/1/2007 49 Male 2/26/2008 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 60 Female 3/3/2008 Physician Brazil
Primary
Concomitant
Staphylococcal Sepsis Other Serious 12/1/2007 55 Male 154 lb 4/22/2008 Physician France
Primary
Concomitant
Thrombocytopenia Other Serious 11/21/2007 Male 6/10/2008 Physician France
Primary
Concomitant
Thrombocytopenia Other Serious 11/21/2007 54 Male 6/10/2008 Other Health Professional France
Primary
Concomitant
Pain In Jaw Other Serious 3/1/2007 49 Male 9/26/2008 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 1/14/2009 Male 265 lb 2/23/2009 Physician Hungary
Primary
Concomitant
Interacting
Tricuspid Valve Incompetence Other Serious 1/1/2009 Male 3/9/2009 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2009 Male 237 lb 3/18/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/1/2009 Female 4/27/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 70 Male 4/29/2009 Consumer United States
Primary
Concomitant
Withdrawal Of Life Support Other Serious 3/1/2009 83 Male 4/30/2009 Physician United States
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization 4/1/2009 Male 130 lb 5/4/2009 United States
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization 4/1/2009 Male 130 lb 5/14/2009 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/1/2009 58 Female 5/19/2009 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 3/1/2009 83 Male 5/19/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/1/2009 58 Female 5/21/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/1/2009 Female 159 lb 5/28/2009 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 3/1/2009 83 Male 6/3/2009 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 3/1/2009 83 Male 6/11/2009 Physician United States
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization 4/1/2009 Male 130 lb 6/22/2009 Pharmacist United States
Primary
Concomitant
Radiotherapy Other Serious 4/1/2009 Male 130 lb 6/26/2009 Pharmacist United States
Primary
Concomitant
Vasculitis Other Serious 4/1/2009 Female 7/2/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 74 Female 7/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/14/2009 Male 265 lb 7/13/2009 Physician Hungary
Primary
Concomitant
Interacting
Renal Failure Acute Other Serious 4/14/2009 Female 156 lb 7/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2009 Female 110 lb 10/16/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 6/15/2009 Male 167 lb 10/17/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/13/2009 Male 132 lb 11/17/2009 Physician Japan
Primary
Concomitant
Toothache Other Serious 10/20/2009 71 Female 11/17/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/22/2009 Male 11/20/2009 Physician Japan
Primary
Concomitant
Pain Other Serious 10/9/2009 Male 11/20/2009 Consumer United States
Primary
Concomitant
Toothache Other Serious 10/20/2009 71 Female 11/25/2009 Physician Japan
Primary
Concomitant
Osteonecrosis Disability 12/6/2006 Male 11/30/2009 Physician France
Primary
Concomitant
Thrombocytopenia Hospitalization 1/14/2009 Male 265 lb 12/1/2009 Physician Hungary
Primary
Concomitant
Interacting
Respiratory Failure Other Serious 3/1/2009 83 Male 12/1/2009 Physician United States
Primary
Concomitant
Toothache Other Serious 11/20/2006 Male 172 lb 1/14/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/22/2009 Male 1/18/2010 Physician Japan
Primary
Secondary
Nicotine Dependence 1/1/2004 65 Female 1/20/2010 Consumer United States
Primary
Secondary
Toothache Other Serious 11/20/2006 Male 172 lb 1/26/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/13/2009 Male 132 lb 2/5/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/22/2009 Male 2/15/2010 Physician Japan
Primary
Secondary
Toothache Other Serious 11/14/2007 71 Female 2/17/2010 Physician Japan
Primary
Concomitant
Toothache Other Serious 11/20/2006 Male 172 lb 2/18/2010 Other Health Professional United States
Primary
Concomitant
Malignant Neoplasm Progression Other Serious Male 2/22/2010 Other Health Professional United States
Primary
Concomitant
Toothache Other Serious 11/14/2007 Female 97 lb 3/11/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/22/2009 Male 3/19/2010 Physician Japan
Primary
Secondary
Tooth Loss Other Serious 8/1/2009 77 Female 3/29/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 11/1/2009 73 Female 116 lb 4/21/2010 Physician United States
Primary
Concomitant
Toothache Other Serious 11/1/2009 70 Female 149 lb 4/26/2010 Other Health Professional United States
Primary
Concomitant
Hepatotoxicity Other Serious Female 5/13/2010 Physician Venezuela
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2006 64 Female 5/17/2010 Physician United States
Primary
Secondary
Concomitant
Lung Disorder Hospitalization 5/27/2010 62 Male 170 lb 6/14/2010 Consumer United States
Primary
Secondary
Concomitant
Splenic Rupture Life Threatening 5/1/2010 65 Female 6/22/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 5/27/2010 62 Male 170 lb 6/25/2010 Consumer United States
Primary
Secondary
Concomitant
Toothache Other Serious 11/20/2006 61 Male 172 lb 7/7/2010 United States
Primary
Concomitant
Toothache Other Serious 11/20/2006 61 Male 172 lb 7/14/2010 United States
Primary
Concomitant
Toothache Other Serious 11/20/2006 61 Male 172 lb 7/16/2010 United States
Primary
Concomitant
Toothache Other Serious 11/20/2006 61 Male 172 lb 9/9/2010 United States
Primary
Concomitant
Renal Failure Hospitalization 8/30/2010 54 Female 11/1/2010 Physician Italy
Primary
Concomitant
Sensory Loss Disability Male 180 lb 11/15/2010 United States
Primary
Concomitant
Weight Decreased Other Serious Female 133 lb 12/18/2010 Physician United States
Primary
Concomitant
Hepatic Failure Hospitalization 12/31/2010 63 Male 1/13/2011 Consumer Japan
Primary
Concomitant
Gastrooesophageal Reflux Disease Other Serious Male 1/25/2011 Physician United States
Primary
Concomitant
Mucosal Inflammation Other Serious Female 133 lb 1/31/2011 Physician United States
Primary
Concomitant
Agranulocytosis Death 11/17/2010 82 Male 128 lb 2/8/2011 Physician Germany
Primary
Concomitant
Hospice Care Death 53 Male 3/2/2011 Physician United States
Primary
Concomitant
Hepatic Failure Death 12/31/2010 63 Male 152 lb 3/14/2011 Consumer Japan
Primary
Concomitant
Renal Failure Death 10/24/2010 86 Male 93 lb 3/8/2011 Consumer Japan
Primary
Concomitant
Cancer Pain Life Threatening 10/24/2010 86 Male 93 lb 3/18/2011 Consumer Japan
Primary
Concomitant
Oedema Peripheral Other Serious Female 133 lb 3/18/2011 Physician United States
Primary
Concomitant
Hospice Care Death 53 Male 4/22/2011 Physician United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Disability 2/10/2011 62 Male 4/26/2011 Consumer France
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Death Male 346 lb 5/4/2011 Other Health Professional United States
Primary
Concomitant
Off Label Use Death 54 Female 5/17/2011 Consumer Venezuela
Primary
Concomitant
Bone Marrow Failure Other Serious 11/17/2010 82 Male 128 lb 5/18/2011 Physician Germany
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 5/19/2011 56 Female 180 lb 5/19/2011 Pharmacist United States
Primary
Concomitant
Metastases To Peritoneum Other Serious 1/23/2006 38 Male 6/4/2011 Physician United States
Primary
Concomitant
Renal Failure Acute Death 10/20/2010 77 Female 6/9/2011 Physician Japan
Primary
Concomitant
Anal Fistula Hospitalization 2/1/2011 6/23/2011 Consumer Italy
Primary
Concomitant
Neutropenia Hospitalization 2/11/2011 61 Male 7/1/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious Female 7/21/2011 Physician United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 3/18/2011 64 Male 132 lb 7/29/2011 Consumer Japan
Primary
Concomitant
Renal Failure Acute Death 10/20/2010 77 Male 8/4/2011 Physician Japan
Primary
Concomitant
Haemoglobin Decreased Disability Female 8/19/2011 Physician United States
Primary
Secondary
Concomitant
Serum Ferritin Increased Disability Female 9/2/2011 Physician United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious Female 9/8/2011 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/11/2011 61 Male 9/9/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious Female 9/19/2011 Lawyer United States
Primary
Secondary
Concomitant
Arteriosclerosis Other Serious Male 9/22/2011 Lawyer United States
Primary
Concomitant
Hypophosphataemia Hospitalization 8/5/2010 61 Female 293 lb 9/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Urine Present Other Serious Male 10/5/2011 Consumer United States
Primary
Concomitant
Rhinitis Allergic Disability Female 11/11/2011 Physician United States
Primary
Secondary
Concomitant
Fibula Fracture Hospitalization Male 11/15/2011 Physician United States
Primary
Concomitant
Neoplasm Malignant Death 8/2/2010 61 Male 177 lb 9/7/2011 Other Health Professional United States
Primary
Concomitant
Rotator Cuff Syndrome Other Serious Male 11/25/2011 Lawyer United States
Primary
Concomitant
Abdominal Pain Upper Hospitalization 1/17/2011 67 Male 157 lb 12/2/2011 Consumer United States
Primary
Secondary
Concomitant
Urethral Obstruction Disability Male 12/2/2011 Lawyer United States
Primary
Concomitant
Abdominal Pain Upper Death 1/17/2011 67 Male 157 lb 12/20/2011 Consumer United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 11/23/2011 58 Male 121 lb 12/20/2011 Physician Germany
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 11/2/2011 71 Female 147 lb 12/27/2011 Other Health Professional United States
Primary
Concomitant
Osteoarthritis Other Serious Male 1/1/2012 Physician United States
Primary
Concomitant
Chest Pain Other Serious Male 1/2/2012 Lawyer United States
Primary
Concomitant
Mental Status Changes Other Serious 11/18/2011 72 Female 115 lb 1/9/2012 Physician United States
Primary
Concomitant
Rash Hospitalization 8/30/2011 74 Female 109 lb 1/19/2012 Physician Japan
Primary
Concomitant
Fatigue Other Serious 11/23/2011 58 Male 121 lb 1/25/2012 Physician Germany
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 12/3/2011 48 Female 94 lb 2/7/2012 Physician Japan
Primary
Concomitant
Vision Blurred Other Serious 11/18/2011 72 Female 115 lb 2/20/2012 Other Health Professional United States
Primary
Concomitant
Abdominal Pain Upper Death 1/17/2011 67 Male 157 lb 2/20/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Pain Other Serious Male 3/19/2012 Physician United States
Primary
Concomitant
Sepsis Hospitalization 3/14/2011 77 Male 187 lb 3/20/2012 Consumer United States
Primary
Secondary
Concomitant
Hallucination, Visual Other Serious 2/7/2012 56 Male 4/18/2012 Physician France
Primary
Concomitant
Osteonecrosis Hospitalization 3/19/2012 59 Male 4/20/2012 Other Health Professional France
Primary
Secondary
Concomitant
Tachycardia Other Serious Male 4/20/2012 Physician United States
Primary
Concomitant
Osteonecrosis Hospitalization 3/19/2012 59 Male 4/20/2012 Other Health Professional France
Primary
Secondary
Concomitant
Bone Pain Other Serious 69 Male 4/30/2012 Pharmacist Japan
Primary
Secondary
Concomitant
Compression Fracture Other Serious 69 Male 5/14/2012 Pharmacist Japan
Primary
Secondary
Concomitant
Rash Hospitalization 1/19/2012 49 Female 5/15/2012 Consumer France
Primary
Concomitant
Osteonecrosis Hospitalization 3/19/2012 59 Male 5/18/2012 Physician France
Primary
Concomitant
Interstitial Lung Disease Death 4/10/2012 72 Male 6/13/2012 Consumer Japan
Primary
Concomitant

Drug Data