Alimta combined with Vitamin B12

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Oesophagitis Hospitalization 11/7/2005 58 Female 12/30/2005 Other Health Professional United States
Primary
Concomitant
Vestibular Disorder Other Serious 9/1/2005 47 Female 1/3/2006 Physician United States
Primary
Concomitant
Sepsis Death 6/20/2005 72 Female 100 lb 11/30/2005 Other Health Professional United States
Primary
Concomitant
Renal Failure Death 1/2/2006 54 Male 1/11/2006 Physician United States
Primary
Concomitant
Mucosal Inflammation Other Serious 11/25/2005 52 Male 1/12/2006 Physician Italy
Primary
Concomitant
Myocardial Infarction Hospitalization 12/30/2005 50 Male 1/11/2006 Physician Italy
Primary
Concomitant
Vomiting Life Threatening 7/12/2005 78 Female 170 lb 1/23/2006 Physician Poland
Primary
Secondary
Concomitant
Cerebrovascular Accident Death 71 Female 1/24/2006 Other Health Professional United States
Primary
Concomitant
Cardiac Arrest Death 11/13/2005 56 Female 1/23/2006 Other Health Professional United States
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 9/13/2005 71 Male 146 lb 1/24/2006 Physician France
Primary
Concomitant
Dyspnoea Hospitalization 8/26/2005 66 Male 168 lb 1/24/2006 Physician France
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/9/2006 50 Male 1/23/2006 Physician Italy
Primary
Concomitant
Vomiting Hospitalization 2/1/2005 73 Male 1/19/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 83 Male 1/24/2006 Other Health Professional United States
Primary
Concomitant
Staphylococcal Sepsis Life Threatening 9/13/2005 71 Male 146 lb 2/1/2006 Physician France
Primary
Concomitant
Cerebrovascular Accident Death 11/13/2005 56 Female 2/2/2006 Other Health Professional United States
Primary
Concomitant
Pleural Mesothelioma Malignant Hospitalization 8/10/2005 75 Female 2/1/2006 Physician Australia
Primary
Concomitant
Pyrexia Other Serious 7/19/2005 62 Male 181 lb 2/6/2006 Physician Netherlands
Primary
Secondary
Concomitant
Pyrexia Other Serious 9/26/2005 76 Male 146 lb 2/10/2006 Physician France
Primary
Concomitant
Pleural Effusion Hospitalization 1/5/2006 58 Female 144 lb 2/10/2006 Other Health Professional United States
Primary
Concomitant
Peripheral Motor Neuropathy Hospitalization 2/1/2006 53 Male 2/19/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/31/2006 66 Female 150 lb 2/22/2006 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 1/5/2006 58 Female 138 lb 2/20/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 8/1/2005 57 Male 139 lb 2/21/2006 Pharmacist France
Primary
Secondary
Concomitant
Neutropenia Other Serious 2/11/2006 42 Male 2/24/2006 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 2/12/2006 Female 2/23/2006 Consumer United States
Primary
Concomitant
Syncope Other Serious 2/10/2006 Male 2/22/2006 United States
Primary
Concomitant
Pleural Effusion Hospitalization 1/5/2006 58 Female 138 lb 2/26/2006 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Other Serious 1/11/2006 42 Male 117 lb 3/4/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/31/2006 66 Female 150 lb 3/2/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/6/2005 62 Female 3/6/2006 Physician Australia
Primary
Secondary
Concomitant
Thromboembolic Stroke Other Serious 10/6/2005 62 Female 3/15/2006 Physician Australia
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/31/2006 66 Female 150 lb 3/14/2006 Physician United States
Primary
Concomitant
Syncope Other Serious 2/10/2006 79 Male 170 lb 3/15/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 5/25/2004 62 Male 190 lb 3/18/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/29/2005 75 Male 140 lb 3/18/2006 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 3/15/2006 66 Female 131 lb 3/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Neuralgia Disability 7/1/2005 72 Male 3/24/2006 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 1/1/2004 73 Female 1/19/2006 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 54 Male 1/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 12/13/2004 70 Female 165 lb 5/22/2006 Physician Poland
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 9/21/2005 68 Female 115 lb 5/18/2006 Pharmacist France
Primary
Concomitant
Urticaria 1/1/2005 Male 3/27/2006 Other Health Professional United States
Primary
Concomitant
Rash 7/1/2005 58 Female 3/27/2006 Physician United States
Primary
Concomitant
Pain 10/1/2005 Male 3/27/2006 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 47 Female 133 lb 6/16/2006 Physician United States
Primary
Concomitant
Musculoskeletal Discomfort 5/1/2006 73 Female 8/10/2006 Consumer United States
Primary
Concomitant
Swelling Face 51 Female 8/10/2006 Consumer United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 1/1/2006 44 Female 8/10/2006 Pharmacist United States
Primary
Concomitant
Renal Cyst Other Serious 1/18/2005 83 Female 8/28/2006 Other Health Professional United States
Primary
Concomitant
Renal Cyst Other Serious 1/18/2005 83 Female 8/29/2006 Other Health Professional United States
Primary
Concomitant
Infection Other Serious 5/24/2006 71 Male 160 lb 11/10/2006 Consumer United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 7/27/2006 44 Female 191 lb 11/10/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/27/2006 49 Male 11/10/2006 Other Health Professional United States
Primary
Concomitant
Malignant Neoplasm Progression Other Serious Male 11/10/2006 Other Health Professional United States
Primary
Concomitant
Platelet Count Decreased Other Serious Male 11/10/2006 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious Male 11/10/2006 Physician United States
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 2/8/2006 65 Female 11/10/2006 Physician United States
Primary
Concomitant
Skin Discolouration Male 11/10/2006 Consumer United States
Primary
Concomitant
Urticaria 8/1/2006 50 Male 11/10/2006 Physician United States
Primary
Concomitant
Hyperkalaemia 8/1/2006 63 Female 11/10/2006 Physician United States
Primary
Concomitant
Hyperkalaemia 8/1/2006 82 Male 11/10/2006 Physician United States
Primary
Concomitant
Periorbital Oedema 1/1/2006 68 Female 11/10/2006 Other Health Professional United States
Primary
Concomitant
Neuralgia 6/1/2006 54 Female 11/10/2006 Consumer United States
Primary
Concomitant
Lacrimation Increased 8/27/2006 83 Female 11/10/2006 Other Health Professional United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome 1/1/2006 Female 11/10/2006 Other Health Professional United States
Primary
Concomitant
Swelling Face 9/1/2005 51 Female 150 lb 11/10/2006 Consumer United States
Primary
Concomitant
Nail Disorder Female 11/10/2006 Consumer United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 2/9/2007 Female 123 lb 3/8/2007 Physician United States
Primary
Secondary
Concomitant
Skin Exfoliation Death 1/1/2006 Female 2/16/2007 Other Health Professional United States
Primary
Concomitant
Fatigue Other Serious 76 Male 2/16/2007 Physician United States
Primary
Concomitant
Dysuria 40 Male 2/16/2007 Other Health Professional United States
Primary
Concomitant
Paraesthesia 10/24/2006 Male 2/16/2007 Physician United States
Primary
Concomitant
Sleep Disorder 11/29/2006 51 Male 2/16/2007 Consumer United States
Primary
Concomitant
Nausea 12/1/2006 Female 2/16/2007 Physician United States
Primary
Concomitant
Lacrimation Increased 1/1/2006 Male 2/16/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased 11/1/2006 Male 2/16/2007 Consumer United States
Primary
Concomitant
Skin Discolouration 60 Male 2/16/2007 Physician United States
Primary
Secondary
Concomitant
Recall Phenomenon 12/4/2006 75 Male 2/16/2007 Physician United States
Primary
Concomitant
Hypersensitivity Hospitalization 7/15/2006 76 Male 197 lb 3/28/2007 Other Health Professional United States
Primary
Concomitant
Urine Output Decreased Other Serious 2/15/2007 62 Female 176 lb 6/15/2007 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 52 Female 210 lb 10/9/2007 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/21/2007 54 Male 6/10/2008 Other Health Professional France
Primary
Concomitant
Thrombocytopenia Hospitalization 6/11/2008 79 Male 133 lb 6/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/11/2008 79 Male 133 lb 9/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/11/2008 79 Male 133 lb 10/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 4/1/2008 74 Male 2/6/2009 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 5/24/2008 Male 2/6/2009 Consumer United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 4/14/2009 75 Male 214 lb 6/18/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Wheezing Hospitalization 6/1/2009 73 Male 115 lb 7/2/2009 Physician United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 4/13/2011 59 Male 199 lb 4/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Neoplasm Malignant Death 8/2/2010 61 Male 177 lb 9/7/2011 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Death 2/11/2011 35 Female 4/17/2012 Physician Japan
Primary
Concomitant
Malaise Life Threatening 1/1/2010 75 Female 126 lb 4/20/2012 Consumer Japan
Primary
Concomitant
Constipation Death 9/21/2010 83 Male 4/24/2012 Consumer Japan
Primary
Concomitant
Blood Glucose Increased Other Serious 3/28/2012 75 Female 112 lb 5/2/2012 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 4/28/2010 66 Male 139 lb 5/16/2012 Consumer Japan
Primary
Concomitant
Blood Glucose Increased Other Serious 3/28/2012 75 Female 112 lb 5/18/2012 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 2/1/2010 Male 5/21/2012 Consumer Japan
Primary
Concomitant
Interstitial Lung Disease Death 4/28/2010 66 Male 139 lb 5/25/2012 Consumer Japan
Primary
Concomitant
Lung Disorder Hospitalization 8/10/2010 74 Female 99 lb 6/12/2012 Consumer Japan
Primary
Concomitant
Lung Disorder Hospitalization 9/29/2010 69 Male 137 lb 6/12/2012 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 6/1/2012 65 Male 7/10/2012 Physician Japan
Primary
Concomitant
Off Label Use Death 6/8/2012 64 Male 203 lb 8/1/2012 Consumer Japan
Primary
Concomitant
Malaise Death 1/1/2010 75 Female 126 lb 8/3/2012 Consumer Japan
Primary
Concomitant
Interstitial Lung Disease Death 2/27/2012 59 Male 126 lb 8/8/2012 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 2/2/2012 63 Male 136 lb 8/15/2012 Physician Japan
Primary
Concomitant
Bone Marrow Failure Other Serious 9/7/2011 70 Male 190 lb 8/15/2012 Physician Japan
Primary
Concomitant
Acute Prerenal Failure Life Threatening 10/30/2009 73 Male 176 lb 8/27/2012 Consumer Japan
Primary
Secondary
Concomitant
Arterial Disorder Other Serious 1/28/2011 67 Male 154 lb 10/11/2012 Consumer Us
Primary
Secondary
Concomitant
Pyrexia Other Serious 73 Male 12/16/2012 Consumer Jp
Primary
Concomitant
Metastases To Stomach Other Serious Female 10/19/2012 Consumer Us
Primary
Concomitant
Thrombocytopenia Hospitalization 55 Female 8/30/2012 Physician De
Primary
Concomitant
Hepatocellular Injury Other Serious 2/27/2012 60 Male 157 lb 9/19/2012 Consumer Fr
Primary
Concomitant
Respiratory Failure Death Male 163 lb 8/30/2012 Physician Us
Primary
Concomitant
Pneumonia Life Threatening 5/23/2012 54 Male 101 lb 11/19/2012 Consumer Be
Primary
Concomitant
Septic Shock Death 6/14/2012 84 Male 209 lb 8/29/2012 Physician Us
Primary
Concomitant
Pain Other Serious Male 10/21/2012 Other Health Professional Fr
Primary
Secondary
Concomitant
Haemolytic Anaemia Hospitalization 6/17/2012 63 Male 10/26/2012 Other Health Professional Fr
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Death Female 89 lb 11/28/2012 Consumer Us
Primary
Concomitant
Chest Pain Male 9/21/2012 Consumer Jp
Primary
Concomitant
Haemolytic Anaemia Hospitalization 6/17/2012 64 Male 10/30/2012 Consumer Fr
Primary
Concomitant
Neoplasm Progression Death 7/28/2012 68 Male 158 lb 9/18/2012 Physician Us
Primary
Concomitant
Skin Toxicity Death 47 Female 10/15/2012 Consumer Ma
Primary
Concomitant
Small Intestinal Perforation Hospitalization Male 161 lb 9/18/2012 Consumer Us
Primary
Concomitant
Sepsis Other Serious 3/8/2012 64 Male 134 lb 9/10/2012 Consumer Us
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/20/2012 49 Male 198 lb 11/16/2012 Consumer Dk
Primary
Concomitant
Thrombocytopenia Hospitalization 7/30/2012 71 Female 10/2/2012 Physician Us
Primary
Concomitant
Pulmonary Embolism Death 4/23/2012 35 170 lb 10/22/2012 Physician Us
Primary
Concomitant
Interstitial Lung Disease Death 79 Male 11/4/2012 Consumer Jp
Primary
Concomitant
Anaphylactic Reaction Other Serious 74 Male 9/23/2012 Consumer Jp
Primary
Concomitant
No Adverse Event 9/2012 Female 10/11/2012 Physician Us
Primary
Concomitant
Liver Disorder Hospitalization 9/18/2012 61 Male 158 lb 11/12/2012 Consumer Jp
Primary
Concomitant
Vasculitis Necrotising Hospitalization 8/30/2012 81 Female 137 lb 10/16/2012 Physician Bg
Primary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 9/3/2012 60 Male 10/2/2012 Consumer Fr
Primary
Concomitant
Malignant Neoplasm Progression Death 8/20/2012 64 Female 284 lb 12/19/2012 Consumer Us
Primary
Concomitant
Malignant Neoplasm Progression Death 8/6/2012 62 Female 11/21/2012 Other Health Professional Us
Primary
Concomitant
Renal Failure Acute Disability 11/17/2010 71 Male 198 lb 12/13/2012 Consumer Jp
Primary
Concomitant
Off Label Use Death 60 Female 10/26/2012 Consumer Pe
Primary
Concomitant
Hypoaesthesia Disability 9/2012 Male 10/12/2012 Consumer Jp
Primary
Concomitant
Rash Pruritic Hospitalization 77 Female 10/16/2012 Consumer Us
Primary
Concomitant
Ejection Fraction Decreased Other Serious 10/12/2012 72 Male 10/17/2012 Consumer Be
Primary
Concomitant
Thrombocytopenia Hospitalization 7/27/2012 81 Male 190 lb 10/17/2012 Consumer Fr
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/2/2012 44 Female 126 lb 10/22/2012 Consumer Jp
Primary
Concomitant
Death Death Male 10/26/2012 Physician Us
Primary
Concomitant
Thrombocytopenia Other Serious 5/19/2012 44 Male 137 lb 10/31/2012 Consumer Fr
Primary
Concomitant
Tetany Hospitalization Male 11/20/2012 Consumer De
Primary
Concomitant
Renal Impairment Hospitalization 68 Female 11/7/2012 Consumer De
Primary
Concomitant
Skin Discolouration Other Serious 54 Male 190 lb 11/19/2012 Consumer At
Primary
Concomitant
Respiratory Distress Hospitalization 2011 67 Female 11/20/2012 Consumer Us
Primary
Concomitant

Drug Data