Alimta combined with Tarceva

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tremor 73 Male 181 lb 12/7/2005 Other Health Professional United States
Primary
Concomitant
Small Intestinal Obstruction Other Serious 2/1/2006 32 Female 2/14/2006 France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/10/2006 Male 184 lb 6/12/2006 Other Health Professional United States
Primary
Secondary
Renal Failure Acute Hospitalization 4/10/2006 56 Female 6/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/19/2005 47 Female 6/21/2006 Pharmacist United States
Primary
Concomitant
Skin Irritation 9/1/2005 Female 5/24/2006 Consumer United States
Primary
Concomitant
Skin Disorder Hospitalization 12/1/2004 82 Male 5/24/2006 United States
Primary
Concomitant
Renal Tubular Acidosis Other Serious 8/1/2005 53 Female 11/7/2006 Physician United States
Primary
Concomitant
Vision Blurred Hospitalization 1/9/2007 Female 1/12/2007 Other Health Professional United States
Primary
Secondary
Blindness Unilateral Hospitalization 1/9/2007 Female 2/19/2007 Other Health Professional United States
Primary
Secondary
Sinus Tachycardia Life Threatening 3/27/2007 Female 132 lb 3/29/2007 Other Health Professional United States
Primary
Secondary
Sinus Tachycardia 3/27/2007 4/5/2007 Consumer United States
Primary
Secondary
Renal Failure Acute Hospitalization 3/1/2007 57 Female 192 lb 5/15/2007 Physician
Primary
Concomitant
Systemic Candida Other Serious 1/1/2005 57 Female 5/21/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2007 57 Female 192 lb 5/21/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Other Serious 3/1/2007 57 Female 192 lb 5/31/2007 Physician France
Primary
Concomitant
Osteonecrosis Other Serious 4/5/2007 77 Male 178 lb 6/12/2007 United States
Primary
Concomitant
Myocardial Infarction Other Serious 6/1/2007 65 Male 7/16/2007 Physician
Primary
Concomitant
Stomatitis Other Serious 4/15/2007 77 Male 178 lb 7/26/2007 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 4/5/2007 77 Male 178 lb 7/28/2007 United States
Primary
Concomitant
Stomatitis Other Serious 4/15/2007 77 Male 178 lb 8/2/2007 Physician United States
Primary
Concomitant
Myocardial Infarction Life Threatening 6/1/2007 65 Male 8/2/2007 Physician
Primary
Concomitant
Myocardial Infarction Life Threatening 6/1/2007 65 Male 8/13/2007 Physician
Primary
Concomitant
Myocardial Infarction Life Threatening 6/1/2007 Male 10/9/2007 Physician
Primary
Concomitant
Myocardial Infarction Life Threatening 6/1/2007 Male 10/9/2007 Physician
Primary
Concomitant
Vomiting Hospitalization 6/28/2008 50 Male 158 lb 6/30/2008 Other Health Professional United States
Primary
Concomitant
Vasculitis Other Serious 5/1/2008 Female 7/17/2008 Physician United States
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 10/1/2007 Female 8/5/2008 Physician Germany
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 50 Male 10/16/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2008 76 Female 141 lb 10/29/2008 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 1/1/2008 50 Male 11/14/2008 Physician United States
Primary
Concomitant
Sexual Relationship Change Other Serious 1/1/1999 66 Male 185 lb 12/15/2008 Consumer United States
Primary
Secondary
Concomitant
Lung Cancer Metastatic Death 1/16/2009 Male 120 lb 3/18/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization Male 4/2/2009 Consumer United States
Primary
Concomitant
Rash Hospitalization 1/1/2008 Male 5/14/2009 Physician France
Primary
Concomitant
Myalgia Hospitalization 4/1/2009 Male 209 lb 5/22/2009 Physician Netherlands
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 4/1/2009 Male 209 lb 6/30/2009 Physician Netherlands
Primary
Concomitant
Hypophagia Hospitalization 7/14/2009 77 Male 170 lb 7/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hypophagia Hospitalization 8/3/2009 77 Male 170 lb 8/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/3/2009 77 Male 170 lb 8/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 8/26/2009 77 Male 170 lb 8/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
No Adverse Event Other Serious 6/1/2009 Male 8/28/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Toxic Skin Eruption Other Serious 7/1/2009 Female 11/8/2009 Physician France
Primary
Concomitant
Myocardial Infarction Life Threatening 6/1/2007 Male 11/30/2009 Physician
Primary
Concomitant
Rash Other Serious 5/1/2008 Female 12/1/2009 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/16/2009 Male 1/18/2010 Consumer France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/16/2009 Male 1/20/2010 Physician France
Primary
Concomitant
Toothache Other Serious 11/14/2007 71 Female 2/17/2010 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 12/28/2009 Male 159 lb 2/25/2010 Physician Japan
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 12/28/2009 Male 159 lb 3/2/2010 Physician Japan
Primary
Secondary
Respiratory Failure Other Serious 12/28/2009 Male 159 lb 3/3/2010 Physician Japan
Primary
Secondary
Toothache Other Serious 11/14/2007 Female 97 lb 3/11/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 12/28/2009 Male 159 lb 3/26/2010 Physician Japan
Primary
Secondary
Thrombocytopenia Other Serious 12/28/2009 Male 159 lb 3/29/2010 Physician Japan
Primary
Secondary
Thrombocytopenia Other Serious 12/28/2009 46 Male 159 lb 4/14/2010 Physician Japan
Primary
Secondary
Thrombocytopenia Other Serious 12/28/2009 46 Male 159 lb 4/14/2010 Physician Japan
Primary
Secondary
Cardiac Failure Hospitalization 72 5/7/2010 Physician United Kingdom
Primary
Concomitant
Cardiac Failure Hospitalization Female 6/4/2010 Physician United Kingdom
Primary
Concomitant
Right Ventricular Failure Hospitalization 4/1/2010 71 157 lb 6/11/2010 Physician United Kingdom
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 4/1/2010 71 Female 157 lb 6/23/2010 Physician United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 61 Female 7/14/2010 Other Health Professional United States
Primary
Concomitant
Left Ventricular Dysfunction Life Threatening 51 Male 10/18/2010 Other Health Professional France
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 1/1/2010 53 Female 137 lb 11/23/2010 Physician Brazil
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious Male 252 lb 12/21/2010 Physician United States
Primary
Concomitant
Hypoaesthesia Other Serious 8/12/2008 72 Female 91 lb 1/6/2011 Physician Japan
Primary
Secondary
Concomitant
Chills Other Serious 11/25/2010 55 Female 2/8/2011 Consumer France
Primary
Concomitant
Death Death 60 Female 2/16/2011 Consumer United States
Primary
Concomitant
Asthenia Hospitalization 1/18/2011 68 Male 2/21/2011 Physician Italy
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 7/5/2010 67 Male 3/9/2011 Physician Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 2/23/2011 75 Male 174 lb 3/9/2011 Consumer Spain
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2010 70 Male 4/18/2011 Physician Italy
Primary
Secondary
Concomitant
Vomiting Other Serious 1/18/2011 68 Male 4/18/2011 Consumer Italy
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 1/1/2011 61 Female 121 lb 4/13/2011 Consumer United States
Primary
Concomitant
Neoplasm Malignant Other Serious 1/1/2010 70 Male 5/18/2011 Physician Italy
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 5/19/2011 56 Female 180 lb 5/19/2011 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Hospitalization 9/17/2010 75 Male 5/26/2011 Physician France
Primary
Concomitant
Segmented Hyalinising Vasculitis Hospitalization 9/17/2010 75 Male 6/2/2011 Physician France
Primary
Concomitant
C-reactive Protein Increased Hospitalization 2/1/2011 63 Male 137 lb 8/10/2011 Physician Japan
Primary
Concomitant
C-reactive Protein Increased Life Threatening 2/1/2011 63 Male 137 lb 8/26/2011 Consumer Japan
Primary
Concomitant
Neutropenia Hospitalization 9/16/2010 75 Male 8/31/2011 Physician France
Primary
Concomitant
Arteriosclerosis Other Serious Male 9/22/2011 Lawyer United States
Primary
Concomitant
Blood Urine Present Other Serious Male 10/5/2011 Consumer United States
Primary
Concomitant
Fibula Fracture Hospitalization Male 11/15/2011 Physician United States
Primary
Concomitant
Extremity Necrosis Other Serious 1/1/2011 49 Female 11/21/2011 Consumer Japan
Primary
Concomitant
Rotator Cuff Syndrome Other Serious Male 11/25/2011 Lawyer United States
Primary
Concomitant
Urethral Obstruction Disability Male 12/2/2011 Lawyer United States
Primary
Concomitant
Dyspnoea Other Serious 55 Female 12/5/2011 Consumer Germany
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 9/22/2011 53 Female 152 lb 12/22/2011 United States
Primary
Secondary
Concomitant
Osteoarthritis Other Serious Male 1/1/2012 Physician United States
Primary
Concomitant
Chest Pain Other Serious Male 1/2/2012 Lawyer United States
Primary
Concomitant
Urine Analysis Abnormal Hospitalization 11/1/2011 62 Female 1/17/2012 Consumer France
Primary
Concomitant
Hyponatraemia Other Serious 4/15/2010 70 Female 93 lb 2/13/2012 Japan
Primary
Secondary
Concomitant
Cough Life Threatening 4/15/2010 70 Female 93 lb 2/16/2012 Japan
Primary
Secondary
Concomitant
Altered State Of Consciousness Other Serious 4/15/2010 70 Female 93 lb 2/22/2012 Physician Japan
Primary
Secondary
Concomitant
Cheilitis Hospitalization 11/4/2011 76 Male 2/24/2012 Consumer France
Primary
Concomitant
Chest Pain Other Serious Male 3/19/2012 Physician United States
Primary
Concomitant
Cachexia Death 4/29/2009 69 Male 4/6/2012 Consumer France
Primary
Concomitant
Cardiac Tamponade Other Serious 10/1/2009 51 Female 4/9/2012 Consumer United States
Primary
Concomitant
Tachycardia Other Serious Male 4/20/2012 Physician United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious Male 161 lb 5/29/2012 Pharmacist United States
Primary
Concomitant
Death Hospitalization 4/29/2009 69 Male 6/8/2012 Consumer France
Primary
Concomitant
C-reactive Protein Increased Other Serious 1/1/2012 71 Male 148 lb 6/14/2012 Physician Japan
Primary
Secondary
Concomitant
Death Death 6/1/2012 52 Female 150 lb 6/15/2012 Consumer United States
Primary
Secondary
Death Death 6/1/2012 52 Female 150 lb 6/15/2012 Other Health Professional United States
Primary
Secondary
Neutropenia Other Serious 2/26/2012 80 Male 104 lb 6/15/2012 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Life Threatening 2/26/2012 80 Male 104 lb 7/30/2012 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Death Male 161 lb 8/2/2012 Pharmacist United States
Primary
Concomitant
Septic Shock Hospitalization 6/24/2012 75 Female 8/2/2012 Other Health Professional France
Primary
Secondary
Concomitant
Septic Shock Hospitalization 6/24/2012 75 Female 8/6/2012 Consumer France
Primary
Secondary
Concomitant
Fatigue Other Serious 61 Female 8/7/2012 Physician Sweden
Primary
Concomitant
Diarrhoea Death 3/14/2012 61 Male 190 lb 8/7/2012 Consumer China
Primary
Concomitant
Renal Salt-wasting Syndrome Hospitalization 4/15/2010 70 Female 93 lb 1/7/2013 Physician Country Not Specified
Primary
Secondary
Concomitant
Xerosis Other Serious 11/4/2011 76 Male 8/23/2013 Consumer Fr
Primary
Secondary
Concomitant
Pleural Effusion Other Serious Female 9/5/2012 Physician Us
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/20/2012 49 Male 198 lb 11/16/2012 Consumer Dk
Primary
Concomitant
Pyrexia Hospitalization 8/20/2012 49 Male 198 lb 7/17/2013 Consumer Dk
Primary
Concomitant
Neuropathy Peripheral Other Serious 2/2008 Female 9/12/2012 Physician Us
Primary
Secondary
Concomitant
Pneumonia Other Serious Male 9/13/2012 Physician Us
Primary
Secondary
Concomitant
Neuropathy Peripheral Death 8/24/2012 52 Male 11/29/2012 Consumer Fr
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 8/23/2012 78 Male 105 lb 8/28/2013 Physician Jp
Primary
Secondary
Disease Recurrence Other Serious 55 Male 10/18/2012 Pharmacist Us
Primary
Secondary
Pain In Extremity Hospitalization 2012 52 Male 10/19/2012 Physician Fr
Primary
Secondary
Paraesthesia Hospitalization 8/2012 Female 11/16/2012 Other Health Professional Se
Primary
Secondary
Concomitant
Pyrexia Death 7/3/2009 67 Female 10/31/2012 Consumer Us
Primary
Concomitant
Metastases To Larynx Other Serious Male 8/25/2012 Physician Us
Primary
Concomitant
Death Death Male 8/30/2012 Physician Us
Primary
Concomitant
Sinus Tachycardia Other Serious Male 216 lb 10/8/2012 Consumer Us
Primary
Concomitant
Death Death Female 9/4/2012 Consumer Us
Primary
Concomitant
Therapy Cessation Death Male 9/5/2012 Physician Us
Primary
Concomitant
Pleural Effusion Other Serious Female 9/5/2012 Physician Us
Primary
Secondary
Concomitant
Pleural Effusion Death Male 172 lb 9/26/2012 Physician Uz
Primary
Concomitant
Rash Death Male 9/6/2012 Physician Us
Primary
Concomitant
Disease Progression Other Serious 9/24/2010 44 Male 12/5/2012 Pharmacist Us
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 76 Female 12/5/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Metastases To Central Nervous System Other Serious 48 Female 12/5/2012 Pharmacist Us
Primary
Secondary
Wrong Technique In Drug Usage Process 12/5/2012 Other Health Professional Us
Primary
Concomitant
Metastases To Lung Other Serious Female 9/8/2012 Physician Us
Primary
Concomitant
Neuropathy Peripheral Other Serious 2/2008 Female 9/12/2012 Physician Us
Primary
Secondary
Concomitant
Pneumonia Other Serious Male 9/13/2012 Physician Us
Primary
Secondary
Concomitant
Weight Decreased Death Male 11/7/2012 Other Health Professional Us
Primary
Concomitant
Unevaluable Event Other Serious 2012 Male 2/5/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Incorrect Dose Administered Other Serious 1/21/2013 76 Male 7/17/2013 Physician Jp
Primary
Concomitant
Skin Toxicity Other Serious 2011 55 Male 3/25/2013 Physician Fr
Primary
Secondary
Concomitant
Skin Toxicity Hospitalization 3/3/2012 56 Male 146 lb 6/11/2013 Physician Fr
Primary
Concomitant
Renal Neoplasm Other Serious 53 Male 5/24/2013 Consumer Us
Primary
Secondary
Concomitant
Vascular Compression Other Serious Female 5/22/2013 Physician Fr
Primary
Secondary
Concomitant
Lower Limb Fracture Other Serious 83 Female 5/24/2013 Physician Gr
Primary
Secondary
Malignant Neoplasm Progression Hospitalization 7/2012 83 Female 5/24/2013 Consumer Gr
Primary
Secondary
Vomiting Hospitalization 5/14/2012 81 Male 6/26/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Pneumatosis Intestinalis Hospitalization 12/4/2012 71 Female 97 lb 8/28/2013 Consumer Jp
Primary
Secondary
Concomitant

Drug Data