Alimta combined with Avastin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Hospitalization 11/2/2005 34 Female 202 lb 1/20/2006 Physician United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 5/23/2005 55 Female 2/2/2006 United States
Primary
Concomitant
Lobar Pneumonia Life Threatening 1/21/2006 65 Female 113 lb 2/7/2006 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious Male 2/7/2006 Physician United States
Primary
Concomitant
Lung Infection Pseudomonal Life Threatening 1/21/2006 65 Female 113 lb 2/28/2006 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/15/2006 66 Female 131 lb 3/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Productive Cough Hospitalization 3/19/2006 56 Female 208 lb 3/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 3/15/2006 66 Female 131 lb 4/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/12/2006 76 Female 119 lb 4/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/10/2006 56 Female 4/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2004 55 Female 5/11/2006 Physician United States
Primary
Concomitant
Scar Hospitalization 4/18/2006 76 Female 120 lb 5/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/12/2006 76 Female 119 lb 5/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhage Death NotSpecified 3/1/2006 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Other Serious Male 5/24/2006 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 4/19/2006 Male 6/1/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/12/2006 76 Female 119 lb 5/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/18/2006 76 Female 120 lb 5/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Productive Cough Hospitalization 3/19/2006 56 Female 208 lb 6/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Death 48 Female 6/5/2006 Physician United States
Primary
Concomitant
Dysphonia 1/25/2006 69 Male 4/24/2006 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/10/2006 56 Female 6/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Required Intervention 51 Male 159 lb 6/23/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 6/16/2006 68 Female 141 lb 6/30/2006 Physician United States
Primary
Secondary
Concomitant
Death Death 62 Male 188 lb 7/6/2006 Other Health Professional United States
Primary
Secondary
Oxygen Saturation Decreased Hospitalization 6/16/2006 68 Female 141 lb 7/7/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Death 62 Male 188 lb 7/17/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/8/2006 62 Female 149 lb 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Productive Cough Hospitalization 3/19/2006 56 Female 208 lb 7/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Rate Increased Hospitalization 3/19/2006 56 Female 7/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Death 62 Male 188 lb 8/2/2006 United States
Primary
Secondary
Concomitant
Bronchospasm Hospitalization 7/1/2006 Female 7/28/2006 Physician United States
Primary
Concomitant
Feeding Tube Complication Hospitalization 8/14/2006 Male 115 lb 8/16/2006 Other Health Professional United States
Primary
Secondary
Diverticulitis Hospitalization 57 Male 9/28/2006 Physician United States
Primary
Secondary
Gallbladder Perforation Hospitalization 63 Male 10/4/2006 Physician United States
Primary
Secondary
Pyrexia Required Intervention 9/15/2006 57 Male 163 lb 10/9/2006 Physician United States
Primary
Secondary
Faecaloma Hospitalization 2/23/2006 69 Female 10/9/2006 Other Health Professional United States
Primary
Secondary
Diverticulitis Required Intervention 9/6/2006 56 Female 119 lb 10/9/2006 Physician United States
Primary
Secondary
Concomitant
Diverticulitis Other Serious 72 Male 10/9/2006 Physician United States
Primary
Concomitant
Gallbladder Perforation Required Intervention 6/19/2006 63 Male 223 lb 10/11/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 9/28/2006 63 Female 164 lb 10/11/2006 Physician United States
Primary
Secondary
Concomitant
Bronchospasm Other Serious 7/14/2006 81 Female 110 lb 10/3/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/23/2006 69 Female 10/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Peritonitis Required Intervention 3/15/2006 72 Male 200 lb 10/27/2006 Physician United States
Primary
Concomitant
Ocular Hyperaemia Hospitalization 11/18/2006 65 Female 12/20/2006 Physician United States
Primary
Secondary
Concomitant
Rash Generalised 69 Male 8/10/2006 Other Health Professional United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 3/1/2006 31 Male 8/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 9/3/2006 65 Female 162 lb 2/1/2007 Physician United States
Primary
Secondary
Concomitant
Keratitis Interstitial Hospitalization 11/18/2006 65 Female 2/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cells Urine Positive Hospitalization 11/13/2006 47 Female 90 lb 2/5/2007 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 66 Female 2/9/2007 Physician United States
Primary
Concomitant
Rash Other Serious 66 Female 2/19/2007 Physician United States
Primary
Concomitant
Disease Progression Death 2/1/2007 Female 161 lb 2/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 2/9/2007 Female 123 lb 3/8/2007 Physician United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/2006 59 124 lb 4/5/2007 Physician United States
Primary
Concomitant
Septic Shock Other Serious 1/1/2007 69 Female 143 lb 4/4/2007 Physician United States
Primary
Concomitant
Large Intestine Perforation Life Threatening 4/4/2007 Female 139 lb 4/9/2007 Pharmacist United States
Primary
Concomitant
X-ray Abnormal Other Serious 9/1/2006 59 Female 124 lb 4/18/2007 United States
Primary
Concomitant
Septic Shock Other Serious 1/1/2007 69 Female 143 lb 5/7/2007 Physician United States
Primary
Concomitant
Mouth Haemorrhage Hospitalization 4/27/2007 Male 146 lb 5/8/2007 Other Health Professional United States
Primary
Secondary
Mouth Haemorrhage Hospitalization 4/24/2007 Male 146 lb 5/8/2007 Other Health Professional United States
Primary
Secondary
Pulmonary Embolism Hospitalization 1/16/2007 Female 161 lb 5/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious Female 5/18/2007 Physician United States
Primary
Concomitant
Dysuria 40 Male 2/16/2007 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/16/2007 Female 161 lb 6/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 76 Male 6/5/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 5/30/2007 Female 6/8/2007 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 4/5/2007 77 Male 178 lb 6/12/2007 United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 66 Male 150 lb 7/11/2007 United States
Primary
Secondary
Concomitant
Sepsis Death 7/3/2007 Male 123 lb 7/6/2007 United States
Primary
Secondary
Thrombocytopenia Hospitalization 76 Male 7/17/2007 Physician United States
Primary
Concomitant
Stomatitis Other Serious 4/15/2007 77 Male 178 lb 7/26/2007 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 4/5/2007 77 Male 178 lb 7/28/2007 United States
Primary
Concomitant
Stomatitis Other Serious 4/15/2007 77 Male 178 lb 8/2/2007 Physician United States
Primary
Concomitant
Throat Tightness Hospitalization 8/16/2007 51 Female 88 lb 8/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tracheal Haemorrhage Death 8/23/2007 Male 163 lb 8/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/30/2007 Female 9/24/2007 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2007 Female 10/9/2007 Consumer United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 10/20/2007 62 Female 107 lb 11/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Haemorrhage Hospitalization 12/23/2007 70 Female 108 lb 12/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 10/20/2007 Female 106 lb 1/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 2/11/2007 72 Male 1/16/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 1/1/2007 49 Male 2/26/2008 United States
Primary
Concomitant
Pneumonia Hospitalization 4/15/2008 83 Male 118 lb 4/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 3/19/2007 68 Male 179 lb 2/28/2008 Other Health Professional United States
Primary
Concomitant
Lobar Pneumonia Hospitalization 4/24/2008 83 Male 118 lb 4/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 1/1/2008 55 Male 5/24/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 4/14/2008 48 Female 187 lb 5/5/2008 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 5/2/2008 48 Female 193 lb 5/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 6/1/2008 53 Male 7/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 5/6/2008 74 Male 119 lb 7/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 6/1/2008 64 Male 209 lb 8/6/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 10/1/2007 Female 8/5/2008 Physician Germany
Primary
Secondary
Concomitant
Large Intestine Perforation Life Threatening 6/1/2008 53 Male 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Large Intestine Perforation Life Threatening 6/1/2008 53 Male 9/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Peritonitis Life Threatening 6/6/2008 Male 9/25/2008 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 1/1/2007 Male 10/3/2008 Consumer United States
Primary
Concomitant
Pain In Jaw Other Serious 3/1/2007 49 Male 9/26/2008 Other Health Professional United States
Primary
Concomitant
Sepsis Life Threatening 6/1/2008 64 Male 209 lb 11/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 6/1/2008 64 Male 209 lb 11/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Oral Infection Hospitalization 11/21/2008 Female 100 lb 11/25/2008 Other Health Professional United States
Primary
Secondary
Scrotal Infection Hospitalization 10/10/2008 Male 156 lb 11/25/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2008 64 Female 132 lb 12/17/2008 Physician Greece
Primary
Concomitant
Intestinal Obstruction Hospitalization 7/23/2008 64 Female 12/23/2008 Other Health Professional Greece
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 1/16/2007 Female 161 lb 12/26/2008 Consumer United States
Primary
Secondary
Concomitant
Metastases To Bone Other Serious Male 1/15/2009 Physician United Kingdom
Primary
Concomitant
Malaise Death 1/28/2009 Female 2/2/2009 Consumer United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death 1/1/2009 Female 2/9/2009 Consumer United States
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 2/13/2009 Male 170 lb 2/24/2009 Physician United States
Primary
Concomitant
Pleural Effusion Other Serious 5/24/2008 Male 2/6/2009 Consumer United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 3/2/2009 Male 197 lb 3/22/2009 Physician United States
Primary
Concomitant
Rash Hospitalization Male 3/24/2009 Physician United Kingdom
Primary
Secondary
Syncope Hospitalization 3/18/2009 Female 159 lb 3/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Flushing Other Serious 3/5/2009 58 Male 4/10/2009 Consumer United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 3/1/2009 83 Male 4/14/2009 Physician United States
Primary
Concomitant
Withdrawal Of Life Support Other Serious 3/1/2009 83 Male 4/30/2009 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 3/2/2009 Male 197 lb 4/29/2009 Physician United States
Primary
Concomitant
Convulsion Hospitalization 4/27/2009 72 Female 5/8/2009 Physician United States
Primary
Concomitant
Rash Hospitalization 1/1/2008 Male 5/14/2009 Physician France
Primary
Concomitant
Respiratory Failure Other Serious 3/1/2009 83 Male 5/19/2009 Physician United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 5/17/2009 Male 204 lb 5/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 5/19/2009 40 Female 175 lb 5/22/2009 Other Health Professional United States
Primary
Secondary
Nausea Hospitalization 5/19/2009 40 Female 175 lb 5/22/2009 Other Health Professional United States
Primary
Secondary
Nausea Hospitalization 5/22/2009 40 Male 173 lb 5/26/2009 Other Health Professional United States
Primary
Secondary
Vomiting Other Serious 3/1/2009 Female 159 lb 5/28/2009 Physician United States
Primary
Concomitant
Pneumonia Other Serious 5/1/2009 Female 175 lb 5/30/2009 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 3/1/2009 83 Male 6/3/2009 Physician United States
Primary
Concomitant
Status Epilepticus Life Threatening 5/4/2009 Male 6/12/2009 Physician Germany
Primary
Concomitant
Respiratory Failure Other Serious 3/1/2009 83 Male 6/11/2009 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 5/29/2009 Female 160 lb 6/11/2009 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 2/1/2008 Female 136 lb 6/19/2009 Physician United States
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 5/2/2009 70 Female 128 lb 6/23/2009 Physician France
Primary
Secondary
Concomitant
Renal Impairment Other Serious 74 Female 6/24/2009 Physician United States
Primary
Concomitant
Transaminases Increased Hospitalization 5/2/2009 Female 6/26/2009 Physician United Kingdom
Primary
Concomitant
Interacting
Transaminases Increased Hospitalization 5/2/2009 Female 6/29/2009 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Other Serious 73 Female 6/30/2009 Physician United States
Primary
Concomitant
Liver Injury Hospitalization 5/2/2009 Female 128 lb 7/1/2009 Physician France
Primary
Concomitant
Status Epilepticus Life Threatening 5/4/2009 Male 7/1/2009 Physician Germany
Primary
Concomitant
Renal Impairment Other Serious 74 Female 7/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperlipidaemia Other Serious Female 146 lb 7/14/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 4/14/2009 Female 156 lb 7/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 5/1/2009 Female 168 lb 7/18/2009 Consumer United States
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 3/5/2009 58 Male 7/23/2009 Consumer United Kingdom
Primary
Concomitant
Hypogammaglobulinaemia Other Serious Male 7/23/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 7/20/2009 Male 107 lb 7/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/20/2009 Male 107 lb 7/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/20/2009 Male 107 lb 7/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2009 73 Female 7/29/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 7/20/2009 Male 107 lb 8/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Peritonitis Life Threatening 5/2/2009 Male 8/5/2009 Physician France
Primary
Concomitant

Drug Data