Alendronate Sodium combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Neoplasm Malignant Other Serious 1/1/2000 47 Male 231 lb 1/4/2006 Lawyer United States
Primary
Concomitant
Pruritus Death 7/22/2004 Male 187 lb 1/25/2006 United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 12/31/2005 60 Male Pharmacist United States
Primary
Concomitant
Tongue Disorder Other Serious 93 Female 3/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Required Intervention 3/16/2006 74 Male 5/9/2006 Other Health Professional United States
Primary
Concomitant
Small Intestine Carcinoma Disability 3/2/2006 67 Female 183 lb 5/18/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Arteriosclerosis Death 4/17/2006 Female 112 lb 7/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Meningioma Death 12/22/2005 Female 152 lb 7/7/2006 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 7/15/2006 57 Female 212 lb 7/19/2006 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 2/1/2003 Female 178 lb 7/26/2006 Consumer United States
Primary
Concomitant
Pruritus Generalised Hospitalization 8/10/2006 Female 9/21/2006 Pharmacist Japan
Primary
Concomitant
Pneumonia Other Serious 8/29/2006 18 Female 130 lb 9/25/2006 Physician Japan
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 4/15/2005 87 Male 134 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 8/24/2006 18 Female 130 lb 10/18/2006 Physician Japan
Primary
Secondary
Concomitant
Optic Ischaemic Neuropathy Hospitalization 51 Male 10/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 Female 11/9/2006 Consumer Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/5/2006 91 Female 11/3/2006 Sweden
Primary
Secondary
Concomitant
Cervical Vertebral Fracture Hospitalization Female 100 lb 11/22/2006 Consumer Canada
Primary
Concomitant
Bone Marrow Failure Other Serious 68 Female 12/7/2006 Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/1/2006 Female 128 lb 8/17/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 8/1/2006 Female 128 lb 8/17/2006 Pharmacist United States
Primary
Secondary
Concomitant
Infection Hospitalization Female 100 lb 1/17/2007 Consumer Canada
Primary
Concomitant
Pneumonia Other Serious 6/14/2006 Male 1/29/2007 Physician Australia
Primary
Concomitant
Sensation Of Heaviness Hospitalization 3/1/2007 51 Male 3/16/2007 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/1/2007 Male 4/20/2007 Pharmacist Australia
Primary
Secondary
Concomitant
Sepsis Death Male 271 lb 4/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Haemorrhage Life Threatening 3/14/2007 79 Male 5/8/2007 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Hospitalization 78 Male 4/30/2007 Other Health Professional United States
Primary
Concomitant
Soft Tissue Infection Other Serious 1/17/2007 Male 271 lb 7/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Headache Hospitalization 10/4/2007 Female 11/2/2007 Physician United States
Primary
Concomitant
Injection Site Haemorrhage 9/21/2007 Female 183 lb 12/14/2007 Consumer United States
Primary
Concomitant
Insulin Autoimmune Syndrome Other Serious 83 Male 12/17/2007 Pharmacist Japan
Primary
Concomitant
Dry Mouth 9/28/2007 Female 12/28/2007 Physician Japan
Primary
Concomitant
Anaemia Other Serious 70 Male 12/21/2007 United Kingdom
Primary
Secondary
Concomitant
Anaemia Other Serious 70 Male 12/21/2007 United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Life Threatening 12/22/2007 63 Female 1/10/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 12/22/2007 63 Female 1/15/2008 United Kingdom
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 10/4/2007 Female 1/25/2008 Physician United States
Primary
Concomitant
Insulin Autoimmune Syndrome Other Serious 83 Male 1/25/2008 Pharmacist Japan
Primary
Concomitant
Rectal Haemorrhage Life Threatening 12/22/2007 63 Female 1/21/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 1/14/2008 69 Female 2/11/2008 United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 12/22/2007 63 Female 2/12/2008 United States
Primary
Secondary
Concomitant
Injection Site Swelling 9/1/2007 Female 118 lb 3/15/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 6/18/2007 Male 140 lb 4/25/2008 Consumer United States
Primary
Concomitant
Interacting
Pleural Effusion Hospitalization 5/1/2008 Female 6/3/2008 Physician Japan
Primary
Concomitant
Injection Site Pain Female 135 lb 6/12/2008 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 4/23/2008 81 Female 6/20/2008 Pharmacist Japan
Primary
Concomitant
Interacting
Thyroid Function Test Abnormal Other Serious 3/1/2007 87 Female 139 lb 7/18/2008 Physician United States
Primary
Secondary
Concomitant
Carcinoma In Situ Of Skin Other Serious 4/4/2007 Female 137 lb 7/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Gastric Haemorrhage Hospitalization 7/6/2008 84 Male 156 lb 8/17/2008 Pharmacist United States
Primary
Secondary
Pulmonary Embolism Life Threatening 5/1/2008 82 Female 8/21/2008 Consumer Canada
Primary
Concomitant
Prothrombin Time Prolonged 4/23/2008 Female 8/27/2008 Pharmacist Japan
Primary
Concomitant
Interacting
International Normalised Ratio Decreased Other Serious Female 8/28/2008
Primary
Secondary
Concomitant
Underdose 6/1/2008 Female 9/12/2008 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Death 83 Female 9/12/2008 United States
Primary
Concomitant
Serotonin Syndrome Other Serious 8/28/2008 Female 10/1/2008 Physician Japan
Primary
Secondary
Concomitant
Sarcoidosis Other Serious 2/1/2008 Female 130 lb 10/3/2008 United Kingdom
Primary
Concomitant
Serotonin Syndrome Hospitalization 8/29/2008 Female 10/10/2008 Physician Japan
Primary
Secondary
Concomitant
Interacting
Pulmonary Embolism Hospitalization Female 123 lb 10/10/2008 Israel
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/27/2008 Female 123 lb 10/16/2008 Israel
Primary
Secondary
Concomitant
Weight Increased Other Serious 29 Female 120 lb 10/18/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyelonephritis Acute Hospitalization 5/14/2008 84 Female 110 lb 10/20/2008 Other Health Professional Japan
Primary
Concomitant
Neutrophilic Panniculitis Other Serious 10/14/2007 Male 10/22/2008 Physician United Kingdom
Primary
Concomitant
Weight Fluctuation Other Serious 29 Female 11/17/2008 Japan
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 9/8/2008 Female 11/26/2008 Physician Japan
Primary
Concomitant
Blood Triglycerides Increased 66 Female 12/4/2008 Physician
Primary
Concomitant
Neutrophilic Panniculitis Other Serious 10/14/2007 Male 12/5/2008 Physician United Kingdom
Primary
Concomitant
Influenza Like Illness 10/6/2008 Female 12/12/2008 Physician United States
Primary
Concomitant
Cardiac Disorder Death 10/6/2008 1/15/2009 Canada
Primary
Concomitant
Sarcoidosis Other Serious 2/1/2008 Female 130 lb 1/19/2009 United Kingdom
Primary
Concomitant
Cardiac Disorder Death 10/6/2008 96 lb 1/20/2009 Canada
Primary
Concomitant
Muscle Spasms Female 180 lb 2/5/2009 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 11/26/2006 72 Female 2/4/2009 Consumer United Kingdom
Primary
Secondary
Mouth Haemorrhage Hospitalization 1/18/2009 Female 3/10/2009 Physician Japan
Primary
Concomitant
Interacting
Product Quality Issue Other Serious 11/21/2008 83 Male 3/9/2009 Consumer United States
Primary
Concomitant
Overdose Hospitalization 12/16/2008 Female 3/23/2009 Physician Denmark
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 12/18/2008 79 Male 151 lb 4/7/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 12/18/2008 Male 151 lb 4/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 12/18/2008 79 Male 150 lb 4/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 12/18/2008 79 Male 4/22/2009 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 12/18/2008 79 Male 4/25/2009 United Kingdom
Primary
Secondary
Concomitant
Epilepsy Other Serious 63 5/13/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Pelvic Fracture Hospitalization 4/18/2009 82 Female 6/1/2009 Physician Norway
Primary
Secondary
Concomitant
Epilepsy Other Serious 5/1/2009 63 6/5/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/9/2009 Female 148 lb 6/22/2009 Physician United Kingdom
Primary
Concomitant
Osteonecrosis Hospitalization 72 Male 6/30/2009 Lawyer United States
Primary
Concomitant
Anaemia Other Serious 66 Female 132 lb 7/31/2009 Physician United Kingdom
Primary
Concomitant
Diabetes Mellitus Death 8/6/2009 84 Male 9/1/2009 Consumer United States
Primary
Concomitant
Tooth Abscess Hospitalization 83 Female 8/28/2009 United Kingdom
Primary
Concomitant
Haemoglobin Decreased Other Serious 4/8/2009 66 Female 132 lb 9/2/2009 Physician United Kingdom
Primary
Concomitant
Anaemia Other Serious 66 Female 132 lb 9/2/2009 Physician United Kingdom
Primary
Concomitant
Anaemia Other Serious 66 Female 132 lb 9/2/2009 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 79 Female 9/8/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Death 8/6/2009 84 Male 9/14/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 79 Female 9/8/2009 United States
Primary
Concomitant
Dyspnoea Hospitalization 12/26/2006 72 Female 9/9/2009 United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 4/8/2009 90 Female 88 lb 8/31/2009 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Other Serious Male 10/19/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 79 Female 11/18/2009 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 11/16/2009 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 11/24/2009 Lawyer United States
Primary
Concomitant
Rib Fracture 6/17/2008 Female 194 lb 12/3/2009 Physician United States
Primary
Concomitant
Transitional Cell Carcinoma Other Serious 10/19/2009 62 Male 12/17/2009 Other Health Professional United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 11/27/2009 Female 170 lb 12/17/2009 Consumer United States
Primary
Secondary
Concomitant
Transitional Cell Carcinoma Other Serious 10/19/2009 62 Male 205 lb 12/29/2009 Other Health Professional United States
Primary
Concomitant
Neutropenia Life Threatening 12/14/2009 Male 184 lb 1/20/2010 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 8/1/2007 Female 143 lb 1/29/2010 Brazil
Primary
Concomitant
Toxic Epidermal Necrolysis Death 12/18/2008 79 Male 150 lb 2/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 12/14/2009 Male 184 lb 2/9/2010 United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 12/18/2008 79 Male 2/1/2010 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 12/18/2008 79 Male 2/1/2010 United Kingdom
Primary
Secondary
Concomitant
Myasthenia Gravis Hospitalization 4/16/2009 Female 257 lb 2/16/2010 Physician South Africa
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/28/2009 Female 2/16/2010 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Life Threatening 5/1/2008 82 Female 2/23/2010 Other Health Professional Canada
Primary
Concomitant
Sudden Death Death 2/2/2010 81 Female 2/23/2010 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 12/1/2009 70 Female 100 lb 2/6/2010 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/10/2009 Female 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 6/2/2009 Male 3/15/2010 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/1/2009 Female 3/23/2010 Physician Japan
Primary
Concomitant
Myocardial Infarction Hospitalization 12/20/2009 71 Female 146 lb 3/29/2010 Physician United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Life Threatening 3/24/2010 3/31/2010 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 11/28/2009 78 Female 4/1/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2006 61 Female 143 lb 4/2/2010 Brazil
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 3/31/2010 United States
Primary
Concomitant
Wheezing Hospitalization 69 Female 4/6/2010 Lawyer United States
Primary
Concomitant
Disease Progression Death 3/28/2010 79 Male 4/12/2010 Consumer United States
Primary
Concomitant
Renal Failure Life Threatening 3/11/2010 77 Female 170 lb 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 1/1/2008 68 Female 4/26/2010 Lawyer United States
Primary
Concomitant
Pneumonia Hospitalization Male 5/4/2010 United States
Primary
Concomitant
Tachycardia Other Serious 1/8/2008 68 Female 190 lb 5/14/2010 Lawyer United States
Primary
Secondary
Concomitant
Pain In Extremity Disability 10/13/2007 44 Female 125 lb 6/18/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 6/6/2010 74 Female 6/24/2010 Physician United States
Primary
Concomitant
Tuberculosis Other Serious 1/1/2008 43 Female 130 lb 7/6/2010 Consumer United Kingdom
Primary
Concomitant
Malaise Other Serious 1/1/2007 72 Female 155 lb 7/30/2010 Consumer United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 8/1/2010 73 Female 8/27/2010 Physician Canada
Primary
Concomitant
International Normalised Ratio Decreased 2/1/2010 78 Female 160 lb 8/28/2010 United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 6/26/2010 79 Female 9/22/2010 Other Health Professional
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization Female 9/30/2010 Physician United States
Primary
Secondary
Concomitant
Chromaturia Other Serious 1/1/2007 65 Female 10/8/2010 Consumer Brazil
Primary
Concomitant
Toxic Epidermal Necrolysis Death 12/18/2008 79 Male 10/11/2010 United Kingdom
Primary
Secondary
Concomitant
Dysphonia 68 Female 10/13/2010 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 10/15/2010 68 Female 154 lb 11/3/2010 Other Health Professional Denmark
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2008 80 Male 140 lb 11/4/2010 Physician United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 8/1/2010 73 Female 11/18/2010 Other Health Professional Canada
Primary
Concomitant
Gynaecomastia 79 Male 177 lb 11/16/2010 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 12/20/2009 12/17/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/15/2010 73 Female 143 lb 1/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Squamous Cell Carcinoma Other Serious 11/18/2010 82 Female 158 lb 3/1/2011 Consumer United Kingdom
Primary
Secondary
Concomitant

Drug Data