Alendronate Sodium combined with Rabeprazole Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rash Hospitalization 11/7/2005 Female 1/11/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Death 11/14/2005 Female 135 lb 1/19/2006 Canada
Primary
Concomitant
Right Ventricular Failure Hospitalization 12/25/2003 78 Male 1/27/2006 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/25/2005 Male 2/15/2006 Physician Japan
Primary
Secondary
Concomitant
Hiatus Hernia Hospitalization 9/6/2005 Female 139 lb 3/14/2006 United States
Primary
Concomitant
Knee Arthroplasty Hospitalization 2/28/2006 Female 3/24/2006 Consumer Canada
Primary
Concomitant
Mammogram Abnormal Other Serious 1/1/2006 46 Female 80 lb 3/28/2006 Other Health Professional United States
Primary
Concomitant
False Positive Laboratory Result Hospitalization 8/25/2005 Male 4/12/2006 Physician Japan
Primary
Secondary
Concomitant
Joint Swelling Other Serious 4/5/2006 Female 128 lb 5/9/2006 Consumer Canada
Primary
Concomitant
Joint Swelling Other Serious 4/5/2006 Female 128 lb 8/14/2006 Physician Canada
Primary
Concomitant
Weight Decreased Hospitalization 6/22/2006 80 Female 150 lb 9/5/2006 Other Health Professional France
Primary
Concomitant
Rectal Haemorrhage Hospitalization 8/24/2006 Female 189 lb 10/20/2006 Physician United States
Primary
Concomitant
Cardiac Murmur Hospitalization 4/24/2006 Female 160 lb 11/16/2006 Consumer Canada
Primary
Concomitant
Cardiomegaly Other Serious 4/24/2006 Female 160 lb 12/14/2006 Consumer Canada
Primary
Concomitant
Hypotension Hospitalization 10/17/2006 Male 1/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 12/17/2005 Female 117 lb 4/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Femur Fracture Other Serious 4/29/2007 Female 150 lb 5/9/2007 Consumer Canada
Primary
Concomitant
Sepsis Hospitalization 6/11/2007 Male 101 lb 7/13/2007 Physician United Kingdom
Primary
Concomitant
Diabetes Mellitus Hospitalization 2/20/2007 Female 7/25/2007 Physician Japan
Primary
Concomitant
Oesophagitis 5/22/2007 73 Male 7/19/2007 Pharmacist United States
Primary
Concomitant
Surgery Hospitalization 4/1/2007 Female 190 lb 12/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective 1/1/2005 Female 101 lb 12/14/2007 Consumer United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 2/20/2007 Female 12/19/2007 Physician Japan
Primary
Concomitant
Streptococcal Sepsis Other Serious 4/1/2007 Female 190 lb 3/7/2008 United Kingdom
Primary
Secondary
Concomitant
Acute Sinusitis 2/1/2008 Female 189 lb 3/15/2008 Consumer United States
Primary
Concomitant
Malaise Other Serious 4/19/2008 Female 6/2/2008 Physician Canada
Primary
Concomitant
Malaise Other Serious 4/19/2008 Female 6/2/2008 Physician Canada
Primary
Concomitant
Pyrexia Hospitalization 7/3/2008 Female 115 lb 7/11/2008 Japan
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 7/18/2008 Japan
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 7/18/2008 Japan
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 7/23/2008 Japan
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 7/25/2008 Japan
Primary
Concomitant
Myocardial Infarction Death 7/30/2008 Female 150 lb 8/15/2008 Canada
Primary
Concomitant
Septic Shock Other Serious 5/31/2008 69 Female 77 lb 8/14/2008 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 5/1/2008 82 Female 8/21/2008 Consumer Canada
Primary
Concomitant
Delirium Other Serious 8/31/2008 79 Female 9/12/2008 Physician Japan
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 9/24/2008 Japan
Primary
Concomitant
Delirium Other Serious 8/31/2008 79 Female 9/29/2008 Physician Japan
Primary
Concomitant
Knee Arthroplasty Hospitalization 4/1/2008 Female 130 lb 10/9/2008 Canada
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 10/17/2008 Japan
Primary
Concomitant
Vomiting Other Serious 8/13/2008 Female 141 lb 10/20/2008 Physician Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 4/1/2008 Female 130 lb 10/23/2008 Canada
Primary
Concomitant
Renal Failure Other Serious 4/1/2003 Female 10/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/13/2008 Female 134 lb 11/20/2008 Physician Japan
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 12/19/2008 Japan
Primary
Concomitant
Somnolence Hospitalization 6/29/2008 80 Female 12/19/2008 France
Primary
Secondary
Concomitant
Vomiting Other Serious 8/13/2008 Female 134 lb 1/15/2009 Physician Japan
Primary
Concomitant
Foot Fracture Other Serious 1/3/2009 67 Female 1/28/2009 Canada
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 10/27/2008 Male 2/26/2009 Japan
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 10/27/2008 Male 6/2/2009 Japan
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 2/25/2009 Female 96 lb 6/16/2009 Japan
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 2/25/2009 Female 96 lb 6/25/2009 Japan
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 10/27/2008 Male 7/21/2009 Japan
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 10/27/2008 Male 8/11/2009 Japan
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 10/27/2008 Male 8/18/2009 Japan
Primary
Concomitant
Vasculitic Rash Other Serious 3/3/2009 Male 192 lb 8/19/2009 United Kingdom
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 8/24/2009 Female 119 lb 9/9/2009 Japan
Primary
Concomitant
Lupus-like Syndrome Other Serious 1/1/2009 Female 290 lb 9/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 5/25/2009 Female 82 lb 9/30/2009 Japan
Primary
Concomitant
Spinal Compression Fracture Hospitalization 5/25/2009 Female 82 lb 12/4/2009 Japan
Primary
Concomitant
Dyspnoea 1/1/2009 Female 290 lb 12/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Impaired Healing Other Serious 1/1/2003 66 Female 12/8/2009 Physician Switzerland
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 6/9/2009 Male 130 lb 1/12/2010 Japan
Primary
Concomitant
Pneumaturia Hospitalization 1/5/2010 Female 1/19/2010 Canada
Primary
Concomitant
Eosinophilic Pneumonia Hospitalization 7/3/2009 Male 115 lb 1/21/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 7/6/2009 Female 119 lb 1/28/2010 Japan
Primary
Concomitant
Decreased Appetite Hospitalization 6/9/2009 Male 130 lb 2/1/2010 Japan
Primary
Concomitant
Pulmonary Embolism Life Threatening 5/1/2008 82 Female 2/23/2010 Other Health Professional Canada
Primary
Concomitant
Pyrexia Hospitalization 7/6/2009 Female 119 lb 3/16/2010 Japan
Primary
Concomitant
Vomiting Hospitalization 12/18/2009 Female 3/10/2010 Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 8/17/2009 70 Male 120 lb 4/2/2010 Japan
Primary
Concomitant
Pyrexia Hospitalization 9/29/2009 61 Male 106 lb 4/9/2010 Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 12/18/2009 68 Female 4/7/2010 Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 9/29/2009 61 Male 106 lb 4/23/2010 Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 9/29/2009 61 Male 106 lb 5/3/2010 Japan
Primary
Secondary
Concomitant
Pneumonia Pneumococcal Hospitalization 12/18/2009 68 Female 5/10/2010 Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 12/18/2009 68 Female 5/19/2010 Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 8/20/2009 72 Female 119 lb 6/9/2010 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 8/20/2009 72 Female 119 lb 7/2/2010 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/27/2010 59 Female 123 lb 7/20/2010 Physician Japan
Primary
Secondary
Concomitant
Myalgia 1/11/2007 77 Female 108 lb 7/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/16/2010 45 Female 152 lb 8/16/2010 Consumer Canada
Primary
Concomitant
Pyrexia Hospitalization 7/16/2010 45 Female 152 lb 8/25/2010 Consumer Canada
Primary
Concomitant
Neutropenic Sepsis Hospitalization 8/4/2009 59 Male 148 lb 9/10/2010 Physician United Kingdom
Primary
Concomitant
Viith Nerve Paralysis Hospitalization 10/23/2010 12/8/2010 Physician Japan
Primary
Concomitant
Viith Nerve Paralysis Hospitalization 10/23/2010 12/13/2010 Physician Japan
Primary
Concomitant
Tooth Fracture 11/9/2009 12/14/2010 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/18/2010 70 Female 12/3/2010 Physician Japan
Primary
Concomitant
Pleurisy Hospitalization 4/1/2009 12/22/2010 Other Health Professional Japan
Primary
Concomitant
Vision Blurred Hospitalization 10/23/2010 12/23/2010 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 8/20/2009 72 Female 119 lb 1/5/2011 Physician Japan
Primary
Concomitant
Pleurisy Hospitalization 3/31/2009 1/20/2011 Other Health Professional Japan
Primary
Concomitant
Vision Blurred Hospitalization 10/23/2010 63 Female 108 lb 2/7/2011 Other Health Professional Japan
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 8/20/2009 72 Female 119 lb 2/8/2011 Physician Japan
Primary
Concomitant
Computerised Tomogram Abdomen Abnormal Hospitalization 9/22/2010 79 Female 95 lb 4/1/2011 Physician Japan
Primary
Secondary
Concomitant
Arthralgia Hospitalization 11/29/2010 86 Female 75 lb 4/5/2011 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 5/31/2008 69 Female 77 lb 4/8/2011 Physician Japan
Primary
Secondary
Concomitant
Skin Induration Other Serious 3/13/2008 41 Female 5/4/2011 Consumer Canada
Primary
Secondary
Concomitant
Pruritus Other Serious 3/13/2008 41 Female 5/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
C-reactive Protein Abnormal Hospitalization 3/1/2011 61 Male 5/17/2011 Physician Japan
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 3/13/2008 41 Female 5/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 3/13/2008 41 Female 5/23/2011 Physician United States
Primary
Secondary
Concomitant
Oedema Hospitalization 3/1/2011 61 Male 5/23/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Failure Death 6/1/2010 59 Female 117 lb 5/25/2011 Physician Japan
Primary
Concomitant
Altered State Of Consciousness Hospitalization 3/1/2010 75 Female 6/7/2011 Physician Japan
Primary
Concomitant
Pneumonia Influenzal Death 1/16/2011 54 Female 106 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Malaise Disability 83 Female 165 lb 7/16/2011 Pharmacist Canada
Primary
Concomitant
Epstein-barr Viraemia Hospitalization 3/23/2006 49 Female 7/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Musculoskeletal Pain Hospitalization 1/1/2011 60 Female 7/25/2011 Physician Canada
Primary
Concomitant
Multi-organ Failure Life Threatening 1/16/2011 54 Female 106 lb 7/27/2011 Consumer Japan
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 11/5/2010 73 Female 127 lb 7/11/2011 Physician
Primary
Secondary
Concomitant
Influenza Life Threatening 1/16/2011 54 Female 106 lb 8/2/2011 Consumer Japan
Primary
Secondary
Concomitant
Hepatic Failure Death 5/30/2010 59 Female 117 lb 8/4/2011 Physician Japan
Primary
Concomitant
Dehydration Hospitalization 1/1/2011 60 Female 8/10/2011 Physician Canada
Primary
Concomitant
Organising Pneumonia Hospitalization 3/5/2010 63 Female 117 lb 8/15/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 7/29/2011 79 Female 106 lb 8/16/2011 Consumer Japan
Primary
Secondary
Concomitant
Self Injurious Behaviour Hospitalization 7/22/2011 87 Female 8/16/2011 Consumer Italy
Primary
Secondary
Hypoglycaemia Hospitalization 6/30/2011 83 Female 8/19/2011 Other Health Professional Japan
Primary
Concomitant
Self Injurious Behaviour Hospitalization 7/22/2011 87 Female 8/16/2011 Italy
Primary
Secondary
Concomitant
Self Injurious Behaviour Hospitalization 7/22/2011 87 Female 8/16/2011 Other Health Professional Italy
Primary
Secondary
Cardiac Failure Hospitalization 6/3/2011 61 Female 99 lb 9/1/2011 Physician Japan
Primary
Concomitant
Arthritis Hospitalization 1/20/2011 60 Female 110 lb 9/2/2011 Physician Japan
Primary
Concomitant
Osteoporosis Other Serious 7/4/2011 77 Female 9/6/2011 Consumer Japan
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Disability 63 Female 77 lb 9/6/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pathological Fracture Disability 63 Female 77 lb 9/2/2011 Other Health Professional United Kingdom
Primary
Concomitant
Oral Discharge Disability 63 Female 9/2/2011 Other Health Professional United Kingdom
Primary
Concomitant
Eczema Other Serious 2/1/2009 72 Male 9/19/2011 Physician Japan
Primary
Secondary
Concomitant
Organising Pneumonia Hospitalization 3/1/2010 63 Female 117 lb 9/23/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pulpitis Dental Hospitalization 9/1/2009 69 Male 132 lb 9/26/2011 Other Health Professional Japan
Primary
Concomitant
Self Injurious Behaviour Hospitalization 7/22/2011 87 Female 9/28/2011 Physician Italy
Primary
Secondary
Pulpitis Dental Hospitalization 9/1/2009 69 Male 132 lb 9/30/2011 Other Health Professional Japan
Primary
Concomitant
Pathological Fracture Hospitalization 63 Female 77 lb 9/26/2011 Other Health Professional United Kingdom
Primary
Concomitant
Jaw Fracture Hospitalization 63 Female 77 lb 9/30/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pathological Fracture Disability 63 Female 9/26/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interstitial Lung Disease Hospitalization 7/29/2011 79 Female 106 lb 10/6/2011 Physician Japan
Primary
Secondary
Concomitant
Conjunctival Haemorrhage Other Serious 5/3/2011 68 Female 10/7/2011 Physician France
Primary
Concomitant
Malaise Hospitalization 9/3/2011 38 Female 132 lb 10/18/2011 Physician Japan
Primary
Concomitant
Escherichia Test Positive Hospitalization 9/27/2011 62 Female 10/18/2011 Physician Japan
Primary
Secondary
Malaise Hospitalization 9/3/2011 38 Female 132 lb 10/21/2011 Japan
Primary
Concomitant
Cardiac Failure Hospitalization 7/4/2008 58 Female 10/24/2011 Physician Japan
Primary
Concomitant
Peritoneal Neoplasm Hospitalization 6/16/2009 73 Female 104 lb 10/27/2011 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/31/2011 77 Female 110 lb 11/3/2011 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/18/2011 65 Male 106 lb 11/3/2011 Physician Japan
Primary
Concomitant
Pancreatitis Acute Death 10/21/2011 57 Female 93 lb 11/7/2011 Physician Japan
Primary
Secondary
Concomitant
Peritoneal Abscess Hospitalization 73 Female 104 lb 11/10/2011 Physician Japan
Primary
Concomitant
Enteritis Other Serious 2/23/2011 16 Female 85 lb 11/14/2011 Physician Japan
Primary
Concomitant
Pancreatitis Acute Death 10/21/2011 57 Female 93 lb 11/18/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 6/3/2011 61 Female 99 lb 11/18/2011 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/31/2011 77 Female 110 lb 11/28/2011 Physician Japan
Primary
Secondary
Concomitant
Pulpitis Dental Hospitalization 9/1/2009 69 Male 132 lb 12/1/2011 Other Health Professional Japan
Primary
Concomitant

Drug Data