Alendronate Sodium combined with Nexium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ulcer Other Serious 12/5/2005 73 Male 194 lb 12/6/2005 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral 4/1/2008 69 Female 148 lb 7/30/2008 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 8/11/2007 45 Female 9/2/2008 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 8/11/2007 45 Female 9/10/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2003 9/15/2008 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 8/11/2007 45 Female 176 lb 9/25/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 8/11/2007 45 Female 176 lb 11/19/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 4/1/2008 12/10/2008 Physician
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/11/2007 45 Female 176 lb 12/18/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 114 lb 12/26/2008 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 8/11/2007 45 Female 176 lb 1/28/2009 Physician United States
Primary
Secondary
Concomitant
Pleurothotonus Hospitalization 98 Male 2/4/2009 France
Primary
Concomitant
Rash Maculo-papular Life Threatening 3/26/2005 Male 177 lb 2/13/2009 Physician United States
Primary
Secondary
Concomitant
Arterial Occlusive Disease Hospitalization 2/3/2009 Female 170 lb 2/20/2009 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2003 Female 155 lb 2/25/2009 Physician United States
Primary
Secondary
Concomitant
Urethral Dilatation Hospitalization 1/17/2009 56 Male 135 lb 2/27/2009 Physician United States
Primary
Secondary
Concomitant
Vasculitis Hospitalization 2/1/2009 Female 170 lb 3/2/2009 Other Health Professional Canada
Primary
Concomitant
Urethral Dilatation Hospitalization 1/17/2009 56 Male 135 lb 3/17/2009 Physician United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 6/4/2009 Female 7/22/2009 Physician United States
Primary
Concomitant
Osteomyelitis Other Serious 12/30/2008 Female 119 lb 7/27/2009 Other Health Professional Netherlands
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 8/18/2009 Lawyer United States
Primary
Concomitant
Vasculitis Hospitalization 2/1/2009 Female 170 lb 9/18/2009 Other Health Professional Canada
Primary
Concomitant
Stasis Dermatitis Other Serious 10/12/2007 68 Female 9/17/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 9/21/2009 United States
Primary
Concomitant
Hip Arthroplasty Other Serious 11/1/2008 81 Female 118 lb 10/21/2009 Consumer United States
Primary
Concomitant
Venous Insufficiency Hospitalization 69 Female 11/18/2009 Consumer United States
Primary
Concomitant
Product Quality Issue 6/25/2009 60 Female 1/4/2010 Consumer United States
Primary
Concomitant
Dyspepsia 11/1/2007 Female 1/4/2010 Consumer United States
Primary
Concomitant
Photophobia 64 Female 120 lb 1/24/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/13/2009 Female 1/29/2010 Physician United States
Primary
Concomitant
Product Quality Issue Other Serious 89 Female 125 lb 2/5/2010 Consumer United States
Primary
Concomitant
Pyrexia 1/14/2010 Male 2/10/2010 Consumer Canada
Primary
Concomitant
Vomiting Hospitalization 12/1/2008 Female 163 lb 2/25/2010 Physician United States
Primary
Concomitant
Dyspnoea Other Serious 2/1/2010 Female 160 lb 3/2/2010 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 Female 155 lb 3/23/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 Female 155 lb 3/26/2010 Physician United States
Primary
Secondary
Concomitant
Intervertebral Disc Degeneration Hospitalization 11/2/2009 69 Female 158 lb 4/5/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 69 Female 4/6/2010 Lawyer United States
Primary
Concomitant
Pyrexia 1/14/2010 41 Male 4/12/2010 Consumer Canada
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Female 4/14/2010 Consumer United States
Primary
Secondary
Skin Exfoliation Other Serious Female 165 lb 4/23/2010 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/26/2010 United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 3/21/2010 81 Male 142 lb 4/26/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 3/22/2010 54 Female 125 lb 4/25/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 5/20/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 5/27/2010 United States
Primary
Secondary
Concomitant
Respiratory Acidosis Death Female 105 lb 6/3/2010 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/3/2010 United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 3/21/2010 81 Male 142 lb 6/8/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/10/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/14/2010 United States
Primary
Secondary
Concomitant
Haemorrhage Life Threatening 4/9/2010 86 Female 137 lb 6/17/2010 Pharmacist United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/23/2010 United States
Primary
Secondary
Concomitant
Intervertebral Disc Degeneration Hospitalization 11/2/2009 69 Female 158 lb 6/25/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 7/7/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 8/2/2010 United States
Primary
Secondary
Concomitant
Skin Burning Sensation Female 152 lb 8/28/2010 Physician United States
Primary
Concomitant
Dyspepsia Other Serious 9/1/2010 69 Female 150 lb 9/6/2010 Pharmacist United States
Primary
Concomitant
Skin Exfoliation Other Serious 4/1/2010 75 Female 180 lb 9/23/2010 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 9/30/2010 United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/2003 66 Female 198 lb 4/4/2011 Consumer United States
Primary
Secondary
Concomitant
Ecchymosis Hospitalization 12/1/2010 71 Female 4/18/2011 Consumer Canada
Primary
Concomitant
Oedema Peripheral Other Serious 10/1/2010 79 Female 110 lb 4/15/2011 Physician United States
Primary
Concomitant
Pain In Jaw 11/1/2010 76 Female 4/29/2011 Consumer United States
Primary
Concomitant
Death Death 12/5/2009 75 Female 131 lb 5/5/2011 Physician United States
Primary
Concomitant
Road Traffic Accident Other Serious 11/20/2010 51 Female 93 lb 5/10/2011 Other Health Professional Canada
Primary
Concomitant
Acute Pulmonary Oedema Hospitalization 12/1/2010 71 Female 5/23/2011 Consumer Canada
Primary
Concomitant
Osteoporosis Life Threatening 1/1/2003 66 Female 439 lb 5/18/2011 Consumer United States
Primary
Secondary
Concomitant
Death Death 12/5/2009 75 Female 131 lb 5/27/2011 Physician United States
Primary
Concomitant
Decreased Appetite Other Serious 10/1/2010 79 Female 108 lb 5/26/2011 Physician United States
Primary
Concomitant
Meniscus Lesion Hospitalization 1/1/2008 63 Female 198 lb 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Bone Density Decreased Other Serious 1/1/2010 Female 6/7/2011 Lawyer United States
Primary
Concomitant
Malaise Disability 1/20/2011 71 Female 6/10/2011 Pharmacist Finland
Primary
Secondary
Concomitant
Wheezing 56 Female 215 lb 6/21/2011 Consumer United States
Primary
Concomitant
Drug Dose Omission Hospitalization 1/1/2010 62 Female 6/27/2011 Consumer United States
Primary
Concomitant
Bone Disorder Other Serious 1/1/2003 66 Female 199 lb 6/21/2011 Consumer United States
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 10/1/2010 79 Female 108 lb 6/28/2011 Physician United States
Primary
Concomitant
Muscle Spasms Hospitalization 12/1/2010 71 Female 6/29/2011 Consumer Canada
Primary
Concomitant
Lichenoid Keratosis Other Serious 1/1/2003 56 Female 155 lb 7/7/2011 Pharmacist United States
Primary
Secondary
Concomitant
Hand Fracture Hospitalization 1/1/2010 62 Female 7/8/2011 Consumer United States
Primary
Concomitant
Sinusitis Other Serious 6/21/2006 60 Female 7/20/2011 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 5/25/2011 68 Male 183 lb 7/21/2011 Other Health Professional Canada
Primary
Concomitant
Bundle Branch Block Other Serious Female 7/22/2011 Consumer United States
Primary
Concomitant
Rotator Cuff Syndrome Disability 6/21/2006 60 Female 7/22/2011 Consumer United States
Primary
Concomitant
Swelling Other Serious 5/1/2011 70 Female 172 lb 7/26/2011 United States
Primary
Concomitant
Cardiomyopathy Other Serious Female 7/27/2011 United States
Primary
Concomitant
Gait Disturbance Other Serious 6/21/2006 60 Female 7/28/2011 Consumer United States
Primary
Concomitant
Gastroenteritis Viral Hospitalization 12/27/2008 75 Female 126 lb 7/25/2011 Physician
Primary
Secondary
Concomitant
Chest Pain Other Serious 2/28/2011 53 Female 124 lb 8/4/2011 Consumer United States
Primary
Secondary
Concomitant
Excessive Granulation Tissue Hospitalization 1/1/2003 56 Female 155 lb 8/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Vascular Stenosis Other Serious 7/21/2006 60 Female 8/8/2011 United States
Primary
Concomitant
Gastroenteritis Viral Hospitalization 12/27/2008 75 Female 126 lb 8/5/2011 Physician
Primary
Secondary
Concomitant
Dysplastic Naevus Other Serious 1/1/2003 56 Female 155 lb 8/11/2011 United States
Primary
Secondary
Concomitant
Fall Hospitalization 12/9/2010 90 Female 143 lb 8/15/2011 Physician Japan
Primary
Concomitant
Oesophageal Ulcer Other Serious 7/21/2006 60 Female 8/17/2011 Consumer United States
Primary
Concomitant
Economic Problem Death Female 7/29/2011 Other Health Professional United States
Primary
Concomitant
Diarrhoea Hospitalization 5/13/2011 89 Female 8/19/2011 Physician France
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2003 56 Female 155 lb 8/20/2011 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 5/25/2011 68 Male 183 lb 8/22/2011 Other Health Professional Canada
Primary
Concomitant
Blood Cholesterol Increased Other Serious 1/1/1998 59 Female 141 lb 8/26/2011 Physician United States
Primary
Secondary
Concomitant
Tendon Disorder Other Serious 1/1/2003 56 Female 155 lb 8/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Cholesterol Increased Hospitalization 7/21/2006 61 Female 8/29/2011 United States
Primary
Concomitant
Cardiomyopathy Other Serious Female 9/6/2011 Physician United States
Primary
Concomitant
Pain In Extremity Disability 7/21/2006 61 Female 9/7/2011 United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 9/1/2011 86 Female 114 lb 9/14/2011 Physician United States
Primary
Concomitant
Chest Injury Other Serious 1/1/2010 62 Female 9/12/2011 Consumer United States
Primary
Concomitant
Heart Rate Increased Other Serious 2/28/2011 53 Female 124 lb 9/15/2011 Consumer United States
Primary
Secondary
Concomitant
Death Death 9/9/2011 68 Female 9/16/2011 Physician United States
Primary
Concomitant
Blood Pressure Increased Other Serious 2/28/2011 53 Female 124 lb 9/19/2011 Physician United States
Primary
Secondary
Concomitant
Fall Hospitalization 5/30/2011 84 Female 9/23/2011 Physician France
Primary
Concomitant
Pain Other Serious 8/1/2002 57 Female 150 lb 9/27/2011 Consumer United States
Primary
Secondary
Concomitant
Dysuria Other Serious 1/1/2000 69 Female 10/5/2011 Physician United States
Primary
Secondary
Concomitant
Arthropathy Other Serious 3/26/2010 Female 10/5/2011 Lawyer United States
Primary
Secondary
Concomitant
Carotid Bruit Other Serious 1/1/2003 57 Female 216 lb 10/5/2011 Physician United States
Primary
Secondary
Concomitant
Synovial Cyst Other Serious 1/1/1998 59 Female 141 lb 10/5/2011 Physician United States
Primary
Secondary
Concomitant
Back Pain Hospitalization 1/1/1998 59 Female 141 lb 10/12/2011 Physician United States
Primary
Secondary
Concomitant
Foot Fracture Other Serious 1/1/1998 59 Female 141 lb 10/14/2011 Physician United States
Primary
Secondary
Concomitant
Intervertebral Disc Degeneration Hospitalization 10/19/1999 66 Female 170 lb 10/17/2011 Physician United States
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 10/31/2007 35 Female 116 lb 10/19/2011 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2011 56 Female 10/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Carpal Tunnel Syndrome Disability 1/1/2000 63 Female 185 lb 10/25/2011 Physician United States
Primary
Secondary
Concomitant
Pathological Fracture Other Serious 12/1/2008 70 Female 10/20/2011 Physician United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 1/1/1998 59 Female 141 lb 10/26/2011 Physician United States
Primary
Secondary
Concomitant
Headache Disability 6/17/2008 69 Female 150 lb 10/25/2011 Lawyer United States
Primary
Concomitant
Acute Myocardial Infarction Death 9/6/2011 86 Female 114 lb 10/28/2011 Physician United States
Primary
Concomitant
Radiculopathy Hospitalization 10/19/1999 66 Female 170 lb 10/31/2011 Physician United States
Primary
Secondary
Concomitant
Muscle Spasms 7/27/2011 77 Female 145 lb 11/3/2011 Consumer United States
Primary
Concomitant
Restless Legs Syndrome Other Serious 1/1/2003 57 Female 216 lb 11/3/2011 Physician United States
Primary
Secondary
Concomitant
Arteriosclerosis Other Serious 1/1/1998 59 Female 141 lb 11/3/2011 Physician United States
Primary
Secondary
Concomitant
Cerebral Haematoma Hospitalization 10/11/2011 67 Female 11/7/2011 Physician France
Primary
Secondary
Concomitant
Cerebral Haematoma Death 10/11/2011 67 Female 11/7/2011 Other Health Professional France
Primary
Secondary
Concomitant
Tenderness Hospitalization 10/1/2011 62 Female 11/8/2011 Pharmacist United States
Primary
Concomitant
Joint Injury Other Serious 10/19/1999 66 Female 170 lb 11/10/2011 Physician United States
Primary
Secondary
Concomitant
Synovial Cyst Other Serious 1/1/2003 57 Female 216 lb 11/11/2011 Physician United States
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 6/9/2011 74 Male 11/11/2011 Physician Finland
Primary
Concomitant
Fatigue Other Serious 1/1/2000 63 Female 185 lb 11/14/2011 Physician United States
Primary
Secondary
Concomitant
Hepatic Enzyme Abnormal 7/27/2011 77 Female 145 lb 11/14/2011 Consumer United States
Primary
Concomitant
Hemiplegia Death 10/11/2011 67 Female 11/18/2011 Other Health Professional France
Primary
Secondary
Concomitant
Obesity Hospitalization 1/1/1996 66 Female 170 lb 11/18/2011 Physician United States
Primary
Secondary
Concomitant
Fracture Nonunion Hospitalization 1/1/1996 66 Female 170 lb 11/23/2011 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 6/30/2011 68 Male 9/8/2011 Consumer United States
Primary
Concomitant
Back Pain 66 Female 11/28/2011 Consumer United States
Primary
Concomitant
Hernia Other Serious 1/1/2000 69 Female 11/29/2011 Physician United States
Primary
Secondary
Concomitant
Fungal Infection Hospitalization 1/1/1999 50 Female 143 lb 12/2/2011 Physician United States
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 5/17/1999 63 Female 185 lb 12/9/2011 Physician United States
Primary
Secondary
Concomitant
Exostosis Hospitalization 1/1/1996 62 Female 170 lb 12/12/2011 Physician United States
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 10/1/2010 79 Female 108 lb 12/20/2011 Physician United States
Primary
Concomitant
Musculoskeletal Pain Hospitalization 1/1/1996 62 Female 170 lb 12/22/2011 Physician United States
Primary
Secondary
Concomitant

Drug Data