Alendronate Sodium combined with Metformin Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pruritus Death 7/22/2004 Male 187 lb 1/25/2006 United Kingdom
Primary
Concomitant
Paradoxical Drug Reaction Hospitalization 1/24/2007 78 Female 112 lb 1/26/2007 Pharmacist United States
Primary
Concomitant
Rheumatoid Nodule Other Serious 60 Female 110 lb 2/23/2007 Physician Brazil
Primary
Concomitant
Arterial Occlusive Disease Hospitalization 5/3/2005 Male 181 lb 3/7/2007 Consumer United Kingdom
Primary
Concomitant
T-cell Lymphoma Other Serious 3/17/2007 Female 170 lb 5/4/2007 Physician United States
Primary
Concomitant
Splenomegaly Other Serious 2/1/2007 Female 170 lb 5/15/2007 Physician United States
Primary
Concomitant
Tremor Hospitalization 3/8/2007 79 Male 161 lb 5/17/2007 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 2/1/2007 Female 170 lb 6/1/2007 Physician United States
Primary
Concomitant
Dizziness Other Serious 7/3/2007 Female 163 lb 7/12/2007 Consumer Brazil
Primary
Concomitant
Malaise Other Serious 7/3/2007 Female 163 lb 7/19/2007 Consumer Brazil
Primary
Concomitant
Malaise Other Serious 7/3/2007 Female 163 lb 8/10/2007 Consumer Brazil
Primary
Concomitant
Drug Interaction Hospitalization 73 Male 8/13/2007
Primary
Secondary
Concomitant
Rib Fracture Hospitalization 7/18/2007 76 Female 238 lb 8/31/2007 Consumer United Kingdom
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 9/6/2007 Consumer United Kingdom
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 9/18/2007 Physician United Kingdom
Primary
Concomitant
Transaminases Increased Other Serious 5/31/2006 73 Female 10/3/2007 Other Health Professional France
Primary
Concomitant
Interacting
Fall Hospitalization 7/18/2007 76 Female 238 lb 10/12/2007 Physician United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 11/1/2007 69 Female 121 lb 12/12/2007 Consumer Brazil
Primary
Secondary
Concomitant
Trichophytosis Other Serious 64 Female 1/31/2008
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 1/26/2008 Male 97 lb 2/8/2008 United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 1/26/2008 Male 97 lb 4/4/2008 United States
Primary
Concomitant
Vomiting Other Serious 2/1/2007 Female 170 lb 5/7/2008 Physician United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 1/26/2008 Male 97 lb 5/21/2008 United States
Primary
Concomitant
Gastritis Hospitalization 3/10/2008 62 Female 5/22/2008 Consumer Singapore
Primary
Secondary
Concomitant
Malaise Hospitalization 7/2/2007 Male 5/30/2008 United Kingdom
Primary
Concomitant
Rash Papular 8/1/2007 Female 150 lb 6/12/2008 Consumer United States
Primary
Concomitant
Pain In Extremity 5/11/2008 Female 143 lb 6/13/2008 United States
Primary
Concomitant
Injection Site Urticaria 5/25/2008 Female 192 lb 6/13/2008 United States
Primary
Concomitant
Gastritis Hospitalization 3/10/2008 62 Female 6/19/2008 Consumer Singapore
Primary
Secondary
Concomitant
Pneumonia Other Serious 12/1/2007 72 Female 7/9/2008 Physician Australia
Primary
Concomitant
Gastritis Hospitalization 3/10/2008 62 Female 7/21/2008 Consumer Singapore
Primary
Secondary
Concomitant
Gastritis Hospitalization 3/10/2008 62 Female 7/29/2008 Consumer Singapore
Primary
Secondary
Concomitant
Osteoporosis Other Serious 7/28/2008 55 Female 198 lb 8/15/2008 Physician United Kingdom
Primary
Concomitant
Osteoporosis Other Serious 7/28/2008 55 Female 198 lb 8/21/2008 Physician United Kingdom
Primary
Concomitant
Post Procedural Complication Other Serious 2/8/2008 70 Female 122 lb 8/26/2008 Consumer United States
Primary
Concomitant
Flushing 7/1/2007 Female 8/27/2008 Pharmacist United States
Primary
Concomitant
Pruritus 7/22/2008 Female 8/27/2008 United States
Primary
Concomitant
Flushing Female 8/29/2008 United States
Primary
Concomitant
Drug Interaction Hospitalization 73 Male 8/6/2007 United Kingdom
Primary
Secondary
Concomitant
Arthralgia Other Serious 1/1/2008 Female 239 lb 10/28/2008 United States
Primary
Concomitant
Osteoporotic Fracture Other Serious 7/28/2008 55 Female 198 lb 11/4/2008 Physician United Kingdom
Primary
Concomitant
Overdose Other Serious 4/17/2008 42 Female 247 lb 11/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Overdose Other Serious 4/17/2008 42 Female 247 lb 11/21/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Chest Discomfort Death 75 Female 231 lb 11/26/2008 Consumer Canada
Primary
Secondary
Blood Triglycerides Increased 66 Female 12/4/2008 Physician
Primary
Concomitant
Vision Blurred 8/1/2007 Male 250 lb 12/12/2008 Consumer United States
Primary
Secondary
Concomitant
Bicytopenia Other Serious 11/25/2008 Male 192 lb 12/18/2008 Physician Canada
Primary
Concomitant
Infective Exacerbation Of Chronic Obstructive Airways Disease Hospitalization 8/19/2007 Male 1/14/2009 United Kingdom
Primary
Concomitant
Myelofibrosis Other Serious 11/25/2008 Male 192 lb 2/17/2009 Physician Canada
Primary
Concomitant
Depression Other Serious 11/4/2008 70 Female 2/12/2009 United Kingdom
Primary
Concomitant
Csf Cell Count Increased Other Serious 64 Female 3/3/2009 Physician United States
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Required Intervention 76 Female 3/11/2009 Turkey
Primary
Concomitant
Dyspnoea Hospitalization 7/11/2008 72 Female 3/5/2009 Consumer United States
Primary
Concomitant
Condition Aggravated Other Serious 77 Female 4/9/2009 Consumer United States
Primary
Secondary
Concomitant
Myelofibrosis Other Serious 11/25/2008 Male 192 lb 4/16/2009 Physician Canada
Primary
Concomitant
Cerebrovascular Accident Other Serious 4/1/2008 Female 4/22/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 2/1/2009 Female 143 lb 5/6/2009 Consumer Brazil
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/24/2009 Female 6/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 7/2/2009 Female 132 lb 7/28/2009 Other Health Professional United States
Primary
Concomitant
Headache 7/16/2009 Male 200 lb 8/29/2009 United States
Primary
Concomitant
Diabetes Mellitus Death 8/6/2009 84 Male 9/1/2009 Consumer United States
Primary
Concomitant
Neoplasm Malignant Other Serious 5/27/2009 Male 276 lb 9/8/2009 United Kingdom
Primary
Concomitant
Incorrect Dose Administered 2/10/2007 Female 135 lb 9/11/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 8/1/2007 Female 150 lb 9/12/2009 Consumer United States
Primary
Concomitant
Pain In Extremity 5/11/2008 Female 143 lb 9/12/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 79 Female 9/8/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Death 8/6/2009 84 Male 9/14/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 79 Female 9/8/2009 United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 1/1/2004 45 Female 153 lb 9/23/2009 United States
Primary
Concomitant
Overdose Other Serious 4/17/2008 42 Female 9/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Wheelchair User Hospitalization 6/29/2009 78 Female 9/24/2009 Physician Japan
Primary
Concomitant
Thrombin Time Prolonged Other Serious 80 Female 10/12/2009 Physician Netherlands
Primary
Concomitant
Muscular Weakness Other Serious 9/15/2009 78 Female 184 lb 11/14/2009 Other Health Professional United States
Primary
Concomitant
Psoriatic Arthropathy Other Serious 8/1/2008 Female 257 lb 11/20/2009 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 79 Female 11/18/2009 United States
Primary
Concomitant
Gastroenteritis Viral Hospitalization 9/9/2009 Female 241 lb 12/2/2009 Physician United States
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Other Serious 70 Male 12/8/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Transitional Cell Carcinoma Other Serious 10/19/2009 62 Male 12/17/2009 Other Health Professional United States
Primary
Concomitant
Dysphagia Hospitalization 1/1/2010 Female 222 lb 1/26/2010 Other Health Professional United States
Primary
Concomitant
Product Quality Issue Other Serious 89 Female 125 lb 2/5/2010 Consumer United States
Primary
Concomitant
Neoplasm Malignant Other Serious 5/27/2009 Male 276 lb 2/5/2010 United Kingdom
Primary
Concomitant
Vomiting 1/23/2010 77 Female 2/12/2010 Other Health Professional United States
Primary
Concomitant
Sudden Death Death 2/2/2010 81 Female 2/23/2010 Physician United States
Primary
Concomitant
Urine Output Decreased Hospitalization 6/2/2009 Male 3/15/2010 United Kingdom
Primary
Concomitant
Blood Creatinine Increased Other Serious 72 Female 130 lb 3/16/2010 Physician Germany
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 7/11/2008 72 Female 4/6/2010 Consumer United States
Primary
Concomitant
Wound Infection Other Serious 11/26/2009 59 Female 178 lb 7/6/2010 Physician Canada
Primary
Secondary
Concomitant
Wound Infection Other Serious 11/26/2009 59 Female 178 lb 7/8/2010 Physician Canada
Primary
Secondary
Concomitant
Myelofibrosis Other Serious 11/25/2008 76 Male 192 lb 7/12/2010 Physician Canada
Primary
Concomitant
Nausea Other Serious 2/1/2010 61 Female 112 lb 7/28/2010 Consumer Brazil
Primary
Concomitant
Thyroid Cancer Other Serious 2/27/2010 56 Female 252 lb 7/28/2010 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 7/1/2008 84 Female 190 lb 7/29/2010 Consumer United States
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 2/27/2010 56 Female 252 lb 8/11/2010 Other Health Professional United States
Primary
Concomitant
Hypotension Hospitalization 8/13/2010 62 Female 206 lb 8/25/2010 Consumer United States
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 9/22/2010 61 Female 11/3/2010 Pharmacist Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/13/2010 62 Female 206 lb 11/13/2010 Physician United States
Primary
Secondary
Concomitant
Headache Other Serious 2/1/2010 61 Female 112 lb 2/1/2011 Consumer Brazil
Primary
Concomitant
Asthenia Other Serious 2/1/2010 61 Female 115 lb 4/4/2011 Consumer Brazil
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 2/8/2009 46 Female 220 lb 4/8/2011 Physician United States
Primary
Concomitant
Chest Discomfort Other Serious Female 3/24/2011 Consumer United Kingdom
Primary
Concomitant
Haematuria Hospitalization 3/30/2011 74 Female 5/10/2011 Consumer United States
Primary
Concomitant
Haematuria Hospitalization 3/30/2011 74 Female 5/31/2011 Physician United States
Primary
Concomitant
Blood Pressure Increased Hospitalization 4/20/2011 79 Female 140 lb 6/10/2011 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/24/2011 Male 128 lb 6/14/2011 Physician Germany
Primary
Concomitant
Tachypnoea Hospitalization 5/7/2011 72 Female 6/14/2011 Other Health Professional United Kingdom
Primary
Concomitant
Wheezing 56 Female 215 lb 6/21/2011 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/1/1996 49 Female 195 lb 6/21/2011 Consumer United States
Primary
Secondary
Concomitant
Cardiac Operation Death 4/1/2011 72 Male 7/12/2011 Consumer United States
Primary
Concomitant
Hypoglycaemia Other Serious 6/11/2011 79 Male 7/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Chronic Right Ventricular Failure Other Serious 7/23/2005 84 Female 7/18/2011 Physician United States
Primary
Secondary
Concomitant
Feeling Cold 9/21/2010 63 Female 160 lb 8/5/2011 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity Female 136 lb 8/6/2011 Consumer United States
Primary
Concomitant
Blood Bicarbonate Decreased Other Serious 7/6/2011 59 Female 8/15/2011 Other Health Professional France
Primary
Secondary
Vomiting Disability 82 Female 136 lb 9/6/2011 Other Health Professional
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 9/1/2011 86 Female 114 lb 9/14/2011 Physician United States
Primary
Concomitant
Vomiting Disability 11/9/2009 82 Female 136 lb 9/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Disability 11/9/2009 82 Female 136 lb 9/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Disability 82 Female 136 lb 9/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Disability 11/9/2009 82 Female 9/9/2011 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Disability 11/9/2009 82 Female 136 lb 9/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Disability 11/9/2009 82 Female 9/19/2011 United Kingdom
Primary
Secondary
Concomitant
Weight Increased 7/18/2011 53 Female 219 lb 9/28/2011 Other Health Professional United States
Primary
Concomitant
Asthma Other Serious 50 Female 9/28/2011 Consumer United Kingdom
Primary
Concomitant
Gastritis Hospitalization 3/10/2008 62 Female 10/6/2011 Consumer Singapore
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious Female 10/7/2011 Physician United States
Primary
Concomitant
Skin Ulcer Other Serious 76 Female 165 lb 10/14/2011 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2011 56 Female 10/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Mouth Ulceration Other Serious 76 Female 165 lb 10/20/2011 Consumer United States
Primary
Concomitant
Pathological Fracture Other Serious 12/1/2008 70 Female 10/20/2011 Physician United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 9/6/2011 86 Female 114 lb 10/28/2011 Physician United States
Primary
Concomitant
Hypertonia Other Serious 8/1/2008 68 Female 11/3/2011 Physician
Primary
Concomitant
Abdominal Pain Upper Other Serious 58 Male 250 lb 11/17/2011 Consumer Canada
Primary
Concomitant
Cardiac Failure Hospitalization 6/3/2011 61 Female 99 lb 11/18/2011 Physician Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 6/23/2011 92 Female 141 lb 11/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 77 Female 11/23/2011 Physician Japan
Primary
Concomitant
Gastric Cancer Other Serious 12/30/2010 63 Male 11/28/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 10/25/2011 77 Female 121 lb 11/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypersensitivity 5/1/2011 81 Female 11/28/2011 Consumer United States
Primary
Concomitant
Cerebral Arteriosclerosis Death 6/23/2011 92 Female 141 lb 11/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Death 6/23/2011 92 Female 141 lb 12/1/2011 Other Health Professional Greece
Primary
Secondary
Concomitant
Syncope Other Serious 6/23/2011 92 Female 141 lb 12/1/2011 Consumer Greece
Primary
Secondary
Concomitant
Pancreatitis Other Serious 8/1/2011 59 Female 11/29/2011 Consumer Japan
Primary
Concomitant
Pneumonia Other Serious 8/16/2006 65 Male 162 lb 12/2/2011 Consumer Canada
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/25/2011 77 Female 121 lb 12/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscle Atrophy Other Serious 58 Male 250 lb 12/19/2011 Consumer Canada
Primary
Concomitant
Neutropenia Hospitalization 10/25/2011 77 Female 121 lb 12/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 8/16/2006 65 Male 162 lb 12/22/2011 Physician Canada
Primary
Concomitant
Aphonia Other Serious 61 Female 12/28/2011 Consumer United States
Primary
Concomitant
Toxicity To Various Agents Hospitalization 9/3/2011 90 Female 12/28/2011 Other Health Professional Italy
Primary
Concomitant
Escherichia Test Positive Hospitalization 7/6/2011 59 Female 1/9/2012 Other Health Professional France
Primary
Secondary

Drug Data