Alendronate Sodium combined with Magnesium Oxide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rash Hospitalization 11/7/2005 Female 1/11/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/27/2005 Female 2/10/2006 Physician Japan
Primary
Concomitant
Delirium Other Serious 1/19/2006 Female 2/17/2006 Pharmacist Japan
Primary
Concomitant
Delirium Other Serious 1/19/2006 Female 3/6/2006 Pharmacist Japan
Primary
Concomitant
Acute Abdomen Hospitalization 10/27/2005 Female 3/17/2006 Physician Japan
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 7/15/2006 57 Female 212 lb 7/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/15/2006 57 Female 212 lb 7/19/2006 Pharmacist United States
Primary
Concomitant
Granulocytopenia Required Intervention 4/7/2006 81 Female 5/23/2006 United States
Primary
Concomitant
Pruritus Generalised Hospitalization 8/10/2006 Female 9/21/2006 Pharmacist Japan
Primary
Concomitant
Pneumonia Other Serious 2/27/2006 62 Female 101 lb 12/6/2006 Japan
Primary
Concomitant
Pulmonary Infarction Life Threatening 1/18/2007 61 Female 3/1/2007 Physician Japan
Primary
Concomitant
Thirst Other Serious 75 Female 4/3/2007 Physician Japan
Primary
Concomitant
Thirst Other Serious 3/23/2007 75 Female 4/6/2007 Physician Japan
Primary
Concomitant
Thirst Other Serious Female 4/25/2007 Physician Japan
Primary
Concomitant
Sinusitis Other Serious 3/1/2005 52 Male 261 lb 7/12/2007 Other Health Professional United States
Primary
Concomitant
Vision Blurred 60 Female 7/20/2007 United States
Primary
Concomitant
Melaena Hospitalization 9/13/2007 Male 10/8/2007 Other Health Professional Japan
Primary
Concomitant
Dry Mouth 9/28/2007 Female 12/28/2007 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 11/23/2007 Female 68 lb 2/1/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 11/23/2007 Female 68 lb 2/13/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 11/28/2007 Female 68 lb 2/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 9/10/2007 27 Male 3/21/2008 Physician United States
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 9/10/2007 27 Male 4/18/2008 Physician United States
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 5/30/2005 Female 117 lb 4/21/2008 Physician Japan
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Other Serious 2/26/2008 Female 4/24/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 6/18/2007 Male 140 lb 4/25/2008 Consumer United States
Primary
Concomitant
Interacting
Inappropriate Antidiuretic Hormone Secretion Other Serious 2/26/2008 Female 4/30/2008 Physician Japan
Primary
Secondary
Concomitant
Intestinal Ischaemia Hospitalization 4/28/2008 Male 111 lb 6/17/2008 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/15/2008 58 Male 6/19/2008 Physician Japan
Primary
Concomitant
Intestinal Ischaemia Hospitalization 4/28/2008 Male 111 lb 7/7/2008 Physician Japan
Primary
Concomitant
Intestinal Ischaemia Hospitalization 4/23/2008 Male 111 lb 8/8/2008 Physician Japan
Primary
Concomitant
Dyskinesia Other Serious 5/4/2008 Male 125 lb 9/5/2008 Physician Japan
Primary
Concomitant
Dyskinesia Other Serious 5/4/2008 Male 125 lb 10/13/2008 Physician Japan
Primary
Concomitant
Transplant Rejection Death 10/4/2007 Female 169 lb 10/8/2008 United States
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 5/30/2005 Female 117 lb 10/20/2008 Physician Japan
Primary
Secondary
Concomitant
Pyelonephritis Acute Hospitalization 5/14/2008 84 Female 110 lb 10/20/2008 Other Health Professional Japan
Primary
Concomitant
Vomiting Other Serious 8/13/2008 Female 141 lb 10/20/2008 Physician Japan
Primary
Concomitant
Nausea Other Serious 9/20/2008 52 Female 104 lb 10/22/2008 Physician Japan
Primary
Secondary
Concomitant
Cerebrovascular Accident Death 1/1/2007 58 Female 11/7/2008 Physician United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 6/24/2008 73 Female 11/14/2008 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 8/13/2008 Female 134 lb 11/20/2008 Physician Japan
Primary
Concomitant
Cerebrovascular Accident Death 1/1/2007 58 Female 11/24/2008 Other Health Professional United States
Primary
Concomitant
Oedema Hospitalization 12/7/2008 83 Female 117 lb 12/26/2008 Consumer Germany
Primary
Concomitant
Vomiting Other Serious 8/13/2008 Female 134 lb 1/15/2009 Physician Japan
Primary
Concomitant
Vomiting Other Serious 8/13/2008 Female 134 lb 2/19/2009 Physician Japan
Primary
Concomitant
Pulmonary Oedema Hospitalization 6/24/2008 73 Female 2/17/2009 Physician Japan
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 12/7/2008 83 Female 117 lb 3/13/2009 Other Health Professional Germany
Primary
Concomitant
Urine Output Decreased Hospitalization 12/7/2008 83 Female 117 lb 3/23/2009 Other Health Professional Germany
Primary
Concomitant
Vomiting Other Serious 8/13/2008 Female 134 lb 4/1/2009 Physician Japan
Primary
Concomitant
Lymphoma Hospitalization 2/16/2009 Female 97 lb 4/10/2009 Physician Japan
Primary
Concomitant
Vomiting Other Serious 9/21/2003 50 Male 266 lb 4/15/2009 United States
Primary
Concomitant
Pyrexia Hospitalization 9/22/2008 Female 94 lb 7/8/2009 Japan
Primary
Concomitant
Haemorrhage Life Threatening 2/9/2009 85 Female 170 lb 7/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Other Serious Female 125 lb 7/28/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 2/18/2009 Female 77 lb 8/3/2009 Physician Japan
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 4/1/2009 Female 125 lb 8/7/2009 Physician United States
Primary
Secondary
Concomitant
Haemorrhage Life Threatening 2/9/2009 85 Female 170 lb 8/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 9/20/2008 52 8/17/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 2/18/2009 Female 77 lb 8/18/2009 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 9/22/2008 Female 94 lb 8/21/2009 Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 8/18/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 9/21/2009 United States
Primary
Concomitant
Somnambulism Other Serious 10/3/2009 53 Male 160 lb 10/7/2009 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 2/18/2009 Female 77 lb 10/22/2009 Physician Japan
Primary
Concomitant
Nausea Hospitalization 6/19/2009 84 Female 10/23/2009 Pharmacist Japan
Primary
Concomitant
Urinary Tract Infection Life Threatening 2/18/2009 Female 77 lb 10/26/2009 Physician Japan
Primary
Concomitant
Nausea Hospitalization 6/19/2009 84 Female 11/9/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 5/28/2009 84 Female 11/13/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Death Death 1/16/2009 68 Female 90 lb 11/18/2009 Physician Japan
Primary
Concomitant
Venous Insufficiency Hospitalization 69 Female 11/18/2009 Consumer United States
Primary
Concomitant
Interstitial Lung Disease Death 1/16/2009 68 Female 90 lb 12/14/2009 Physician Japan
Primary
Concomitant
Serotonin Syndrome Other Serious 11/10/2009 74 Male 12/28/2009 Pharmacist Japan
Primary
Concomitant
Tic Other Serious 11/10/2009 74 Male 1/19/2010 Pharmacist Japan
Primary
Concomitant
Septic Shock Hospitalization 12/9/2008 Male 2/12/2010 Physician Japan
Primary
Secondary
Concomitant
Dyspnoea Other Serious 9/20/2008 52 Female 101 lb 2/16/2010 Japan
Primary
Secondary
Concomitant
Synovial Rupture Hospitalization 12/16/2009 Female 2/25/2010 Japan
Primary
Secondary
Concomitant
Synovial Rupture Hospitalization 12/16/2009 Female 3/2/2010 Japan
Primary
Secondary
Concomitant
Retinal Vein Occlusion Other Serious 84 Female 75 lb 3/10/2010 Consumer Japan
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/10/2009 Female 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 2/3/2009 Male 3/16/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 12/18/2009 Female 3/10/2010 Japan
Primary
Concomitant
Urine Abnormality Other Serious 8/11/2008 Female 123 lb 3/19/2010 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 12/9/2008 Male 132 lb 3/23/2010 Physician Japan
Primary
Secondary
Concomitant
Retinal Vein Occlusion Other Serious 84 Female 75 lb 3/30/2010 Physician Japan
Primary
Concomitant
Wheezing Hospitalization 69 Female 4/6/2010 Lawyer United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 12/18/2009 68 Female 4/7/2010 Japan
Primary
Secondary
Concomitant
Renal Failure Life Threatening 3/11/2010 77 Female 170 lb 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 9/20/2008 52 Female 101 lb 4/27/2010 Japan
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 3/18/2010 86 Female 4/27/2010 Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 3/18/2010 86 Female 4/29/2010 Japan
Primary
Secondary
Concomitant
Retinal Vein Occlusion Other Serious 84 Female 75 lb 4/30/2010 Physician Japan
Primary
Concomitant
Pneumonia Pneumococcal Hospitalization 12/18/2009 68 Female 5/10/2010 Japan
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 3/18/2010 86 Female 5/18/2010 Japan
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 9/20/2008 52 Female 101 lb 5/19/2010 Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 2/1/2010 67 Female 90 lb 5/24/2010 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 12/18/2009 68 Female 5/19/2010 Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 2/1/2010 67 Female 90 lb 6/30/2010 Physician Japan
Primary
Concomitant
Urine Output Decreased Other Serious 3/10/2010 72 Female 108 lb 8/25/2010 Physician Japan
Primary
Secondary
Concomitant
Death Death 2/16/2009 56 Male 118 lb 8/26/2010 Physician Japan
Primary
Concomitant
Myocardial Ischaemia Death 2/16/2009 56 Male 118 lb 9/13/2010 Physician Japan
Primary
Concomitant
Urine Output Decreased Other Serious 3/10/2010 72 Female 108 lb 10/7/2010 Physician Japan
Primary
Secondary
Concomitant
Wound Infection Hospitalization 9/25/2010 70 Female 10/7/2010 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Disability 8/23/2010 73 Female 93 lb 10/13/2010 Physician Japan
Primary
Concomitant
Wound Infection Hospitalization 9/25/2010 70 Female 10/11/2010 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Disability 8/23/2010 73 Female 93 lb 11/2/2010 Physician Japan
Primary
Concomitant
Myocardial Ischaemia Death 2/16/2009 56 Male 118 lb 11/11/2010 Physician Japan
Primary
Concomitant
Wound Infection Hospitalization 9/25/2010 70 Female 11/3/2010 Other Health Professional Japan
Primary
Concomitant
Vomiting Other Serious 12/17/2009 73 Female 117 lb 11/15/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Death 3/29/2009 61 Female 12/6/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/24/2005 54 Female 115 lb 12/6/2010 Physician Japan
Primary
Secondary
Concomitant
Wound Infection Hospitalization 9/25/2010 70 Female 11/29/2010 Other Health Professional Japan
Primary
Concomitant
Respiratory Failure Life Threatening 6/20/2009 63 Male 107 lb 12/3/2010 Physician Korea, Republic Of
Primary
Concomitant
Respiratory Failure Death 3/29/2009 62 Female 12/17/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 9/25/2010 70 Female 12/15/2010 Other Health Professional Japan
Primary
Concomitant
Subcutaneous Abscess Hospitalization 12/16/2009 56 Female 12/15/2010 Japan
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 12/17/2009 73 Female 117 lb 4/5/2011 Physician Japan
Primary
Concomitant
Nephrogenic Anaemia Hospitalization 4/14/2009 72 Male 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 4/28/2011 85 Female 101 lb 6/21/2011 Pharmacist Japan
Primary
Concomitant
Interacting
Iron Deficiency Anaemia Other Serious 4/19/2010 81 Female 91 lb 6/22/2011 Physician Japan
Primary
Concomitant
Pneumonia Influenzal Death 1/16/2011 54 Female 106 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Pleurisy Hospitalization 6/1/2011 65 Female 97 lb 7/18/2011 Other Health Professional Japan
Primary
Concomitant
Epstein-barr Viraemia Hospitalization 3/23/2006 49 Female 7/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Multi-organ Failure Life Threatening 1/16/2011 54 Female 106 lb 7/27/2011 Consumer Japan
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 7/15/2011 96 Male 163 lb 7/28/2011 Pharmacist United States
Primary
Concomitant
Influenza Life Threatening 1/16/2011 54 Female 106 lb 8/2/2011 Consumer Japan
Primary
Secondary
Concomitant
Lung Infection Hospitalization 5/1/2011 50 Female 122 lb 8/31/2011 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 5/1/2011 50 Female 122 lb 9/9/2011 Consumer United States
Primary
Concomitant
Hepatic Function Abnormal Life Threatening 2/10/2011 70 Male 11/1/2011 Physician Japan
Primary
Secondary
Concomitant
Enteritis Other Serious 2/23/2011 16 Female 85 lb 11/14/2011 Physician Japan
Primary
Concomitant
Sinus Bradycardia Life Threatening 2/10/2011 70 Male 11/29/2011 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/23/2006 49 Female 12/5/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Hepatic Failure Hospitalization Male 75 lb 12/6/2011 United States
Primary
Concomitant
Enteritis Other Serious 2/23/2011 16 Female 85 lb 12/9/2011 Physician Japan
Primary
Concomitant
Bradypnoea Life Threatening 11/1/2011 87 Female 77 lb 12/14/2011 Physician Japan
Primary
Concomitant
Lung Infection Pseudomonal Life Threatening 6/1/2011 65 Female 88 lb 1/3/2012 Physician Japan
Primary
Concomitant
Pleurisy Hospitalization 6/1/2011 65 Female 88 lb 1/26/2012 Japan
Primary
Concomitant
Pleurisy Hospitalization 6/1/2011 65 Female 88 lb 2/1/2012 Physician Japan
Primary
Concomitant
Blood Albumin Decreased 12/14/2009 72 Female 108 lb 2/13/2012 Physician Japan
Primary
Concomitant
Autoimmune Hepatitis Hospitalization 6/4/2010 65 Female 2/16/2012 Japan
Primary
Concomitant
Enteritis Other Serious 2/23/2011 16 Female 85 lb 2/29/2012 Physician Japan
Primary
Concomitant
Hypoalbuminaemia Other Serious 8/19/2009 65 Female 121 lb 3/23/2012 Physician Japan
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 8/19/2009 65 Female 121 lb 3/26/2012 Physician Japan
Primary
Concomitant
Neutrophil Count Increased Other Serious 5/9/2011 48 Female 152 lb 4/20/2012 Physician Japan
Primary
Secondary
Concomitant
Nocardiosis Death 11/10/2007 79 Male 123 lb 5/8/2012 Physician Japan
Primary
Concomitant
Respiratory Failure Death Male 5/23/2012 Consumer United States
Primary
Concomitant
Headache Death 10/8/2010 76 Male 154 lb 6/18/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Peripheral Arterial Occlusive Disease Other Serious 4/19/2010 81 Female 91 lb 7/3/2012 Physician Japan
Primary
Concomitant
Respiratory Acidosis Hospitalization 11/1/2011 87 Female 77 lb 7/12/2012 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 5/27/2012 60 Female 126 lb 7/12/2012 Physician Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Death 10/8/2010 76 Male 154 lb 7/17/2012 Other Health Professional Japan
Primary
Secondary
Concomitant

Drug Data