Alendronate Sodium combined with Lasix

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tumour Lysis Syndrome Other Serious 4/20/2004 53 Female 95 lb 1/31/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 5/4/2002 59 Female 233 lb 2/24/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/20/2006 58 Male 128 lb 4/13/2006 Physician Japan
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 4/15/2005 87 Male 134 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Infarction Life Threatening 1/18/2007 61 Female 3/1/2007 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 2/21/2007 77 Female 5/2/2007 Spain
Primary
Secondary
Concomitant
Pulmonary Infarction Life Threatening 1/18/2007 61 Female 5/17/2007 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 1/18/2007 61 Female 6/1/2007 Physician Japan
Primary
Secondary
Concomitant
Sinusitis Other Serious 3/1/2005 52 Male 261 lb 7/12/2007 Other Health Professional United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 2/20/2007 Female 7/25/2007 Physician Japan
Primary
Concomitant
Myocardial Infarction Death 6/25/2007 Male 118 lb 8/1/2007 Other Health Professional United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 12/17/2006 Female 8/8/2007 Physician United States
Primary
Concomitant
Pneumonia Bacterial Hospitalization 12/17/2006 Female 8/15/2007 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2007 64 Female 8/20/2007 Consumer United States
Primary
Concomitant
Respiratory Failure Other Serious 12/18/2006 61 Female 110 lb 10/4/2007 Physician Japan
Primary
Secondary
Concomitant
Chest Discomfort Death 75 Female 10/25/2007 Other Health Professional Canada
Primary
Secondary
Insulin Autoimmune Syndrome Other Serious 83 Male 12/17/2007 Pharmacist Japan
Primary
Concomitant
Diabetes Mellitus Hospitalization 2/20/2007 Female 12/19/2007 Physician Japan
Primary
Concomitant
Myocardial Infarction Death 6/25/2007 Male 118 lb 1/16/2008 Other Health Professional United States
Primary
Concomitant
Insulin Autoimmune Syndrome Other Serious 83 Male 1/25/2008 Pharmacist Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/4/2007 64 Male 139 lb 2/1/2008 Physician Japan
Primary
Secondary
Concomitant
Skin Exfoliation Hospitalization 1/1/2008 84 Female 4/25/2008 Physician Brazil
Primary
Concomitant
Skin Exfoliation Hospitalization 3/1/2008 84 Female 5/5/2008 Physician Brazil
Primary
Concomitant
Urinary Incontinence Hospitalization 1/19/2006 78 Male 193 lb 5/9/2008 Physician United States
Primary
Secondary
Concomitant
Thrombin-antithrombin Iii Complex Abnormal Other Serious 12/18/2006 61 Female 110 lb 5/9/2008 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 5/1/2008 Female 5/20/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/30/2007 60 Male 234 lb 5/16/2008 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 5/1/2008 Female 6/3/2008 Physician Japan
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 4/23/2008 81 Female 6/20/2008 Pharmacist Japan
Primary
Concomitant
Interacting
Respiratory Failure Other Serious 12/18/2006 61 Female 110 lb 7/18/2008 Physician Japan
Primary
Secondary
Concomitant
Prothrombin Time Prolonged 4/23/2008 Female 8/27/2008 Pharmacist Japan
Primary
Concomitant
Interacting
Mental Status Changes Hospitalization 7/23/2008 73 Female 189 lb 9/10/2008 Other Health Professional United States
Primary
Concomitant
Death Death 5/18/2008 108 lb 9/30/2008 Japan
Primary
Concomitant
Cardiac Failure Death 5/18/2008 Female 108 lb 10/10/2008 Japan
Primary
Concomitant
Pyelonephritis Acute Hospitalization 5/14/2008 84 Female 110 lb 10/20/2008 Other Health Professional Japan
Primary
Concomitant
Nausea Other Serious 9/20/2008 52 Female 104 lb 10/22/2008 Physician Japan
Primary
Secondary
Concomitant
Swelling Other Serious Female 10/27/2008 Physician United States
Primary
Concomitant
Swelling Other Serious Female 10/31/2008 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 12/18/2006 61 Female 11/18/2008 Physician Japan
Primary
Secondary
Concomitant
Chest Discomfort Death 75 Female 231 lb 11/26/2008 Consumer Canada
Primary
Secondary
Death Death 75 Female 1/30/2009 Other Health Professional Canada
Primary
Secondary
Hepatic Function Abnormal Life Threatening 1/3/2009 3/13/2009 Physician Japan
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 7/11/2008 72 Female 3/5/2009 Consumer United States
Primary
Concomitant
Pyrexia Life Threatening 1/3/2009 3/24/2009 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening 1/3/2009 3/30/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 9/21/2003 50 Male 266 lb 4/15/2009 United States
Primary
Concomitant
Death Death 5/1/2009 Female 96 lb 5/20/2009 Consumer United States
Primary
Concomitant
Pneumonia Necrotising Hospitalization 6/22/2008 71 Female 117 lb 5/27/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Right Ventricular Failure Death 5/1/2009 Female 96 lb 5/29/2009 Physician United States
Primary
Concomitant
Sepsis Hospitalization 5/12/2008 Female 163 lb 7/13/2009 Germany
Primary
Concomitant
Renal Impairment Other Serious 4/1/2009 75 7/15/2009 Pharmacist Japan
Primary
Concomitant
Renal Impairment Other Serious 4/1/2009 75 7/21/2009 Japan
Primary
Concomitant
Rectal Haemorrhage Hospitalization 6/4/2009 Female 7/22/2009 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Other Serious Female 125 lb 7/28/2009 Physician United States
Primary
Secondary
Concomitant
Death Death 7/2/2009 Female 132 lb 7/28/2009 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 3/26/2009 71 7/31/2009 Physician Japan
Primary
Concomitant
Urinary Tract Infection Life Threatening 2/18/2009 Female 77 lb 8/3/2009 Physician Japan
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 4/1/2009 Female 125 lb 8/7/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/26/2008 85 Female 8/3/2009 Lawyer United States
Primary
Concomitant
Sepsis Hospitalization 3/26/2009 71 8/11/2009 Physician Japan
Primary
Concomitant
Dyspnoea Other Serious 9/20/2008 52 8/17/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/26/2008 85 Female 8/10/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 2/18/2009 Female 77 lb 8/18/2009 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 4/26/2008 85 Female 8/26/2009 United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/4/2007 64 Male 139 lb 10/13/2009 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 2/18/2009 Female 77 lb 10/22/2009 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious Male 10/19/2009 United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 2/18/2009 Female 77 lb 10/26/2009 Physician Japan
Primary
Concomitant
Bone Marrow Failure Other Serious 9/14/2009 79 10/27/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Decreased Required Intervention 8/27/2009 71 Female 96 lb 10/22/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/4/2007 64 Male 139 lb 10/24/2009 Physician Japan
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 10/1/2009 Male 190 lb 11/9/2009 Consumer United States
Primary
Concomitant
Bone Marrow Failure Other Serious 9/14/2009 79 Female 11/20/2009 Japan
Primary
Secondary
Concomitant
Weight Decreased Required Intervention 8/27/2009 71 Female 96 lb 11/17/2009 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 11/16/2009 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 11/24/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 4/26/2008 85 Female 12/1/2009 United States
Primary
Concomitant
Oedema Hospitalization 6/1/2009 63 Male 170 lb 11/16/2009 Physician United States
Primary
Concomitant
Low Density Lipoprotein Increased 1/1/2009 72 Female 162 lb 12/21/2009 Consumer United States
Primary
Concomitant
Chest Discomfort Death 75 Female 12/18/2009 Canada
Primary
Secondary
Pneumonia Hospitalization 8/2/2009 72 Female 152 lb 1/7/2010 Consumer Brazil
Primary
Concomitant
Aphonia 12/3/2009 Female 1/13/2010 Consumer
Primary
Concomitant
Neutropenia Life Threatening 12/14/2009 Male 184 lb 1/20/2010 United States
Primary
Secondary
Concomitant
Dysphonia 12/3/2009 Female 1/27/2010 Physician
Primary
Concomitant
Neutropenia Other Serious 12/14/2009 Male 184 lb 2/9/2010 United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 9/20/2008 52 Female 101 lb 2/16/2010 Japan
Primary
Secondary
Concomitant
Cardiac Arrest Hospitalization Female 162 lb 2/25/2010 Consumer United States
Primary
Concomitant
Disease Progression Death 9/28/2009 74 Male 3/6/2010 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/14/2010 Female 202 lb 3/19/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/1/2009 Female 3/23/2010 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 3/31/2010 United States
Primary
Concomitant
Colitis Hospitalization 3/14/2010 78 Female 202 lb 4/8/2010 Physician United States
Primary
Secondary
Concomitant
Fluid Retention Hospitalization Female 162 lb 4/22/2010 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 7/11/2008 72 Female 4/6/2010 Consumer United States
Primary
Concomitant
Right Ventricular Failure Other Serious 9/20/2008 52 Female 101 lb 4/27/2010 Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 3/1/2010 72 Male 5/5/2010 Physician United States
Primary
Concomitant
Right Ventricular Failure Other Serious 9/20/2008 52 Female 101 lb 5/19/2010 Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 2/1/2010 67 Female 90 lb 5/24/2010 Physician Japan
Primary
Concomitant
Erythema Multiforme Hospitalization 4/7/2010 64 Female 86 lb 5/28/2010 Physician Japan
Primary
Secondary
Chest Discomfort Death 75 Female 6/4/2010 Other Health Professional Canada
Primary
Secondary
Ventricular Tachycardia Other Serious 37 Male 6/7/2010 United States
Primary
Concomitant
Death Death 6/14/2010 68 Female 92 lb 6/23/2010 Consumer United States
Primary
Concomitant
Death Death 72 Female 88 lb 6/23/2010 Physician Japan
Primary
Concomitant
Cardiac Failure Hospitalization 2/1/2010 67 Female 90 lb 6/30/2010 Physician Japan
Primary
Concomitant
Pulmonary Hypertension Death 72 Female 88 lb 6/30/2010 Physician Japan
Primary
Concomitant
Erythema Multiforme Hospitalization 4/7/2010 64 Female 86 lb 7/8/2010 Physician Japan
Primary
Secondary
Pneumonia Hospitalization 6/6/2010 74 Female 7/16/2010 Physician United States
Primary
Concomitant
Colitis Hospitalization 3/14/2010 78 Female 202 lb 7/29/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/6/2010 74 Female 8/5/2010 Physician United States
Primary
Concomitant
Hyperkalaemia Other Serious 7/28/2010 87 Female 8/11/2010 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 6/6/2010 74 Female 8/13/2010 Physician United States
Primary
Concomitant
Insomnia Hospitalization 8/5/2008 80 Female 86 lb 8/23/2010 Physician Japan
Primary
Concomitant
Diverticulum Hospitalization 3/14/2010 78 Female 194 lb 8/23/2010 Physician United States
Primary
Secondary
Concomitant
Death Death 2/16/2009 56 Male 118 lb 8/26/2010 Physician Japan
Primary
Concomitant
Thrombophlebitis Other Serious 10/10/2006 74 Female 8/25/2010 Physician United States
Primary
Concomitant
Microcytic Anaemia Hospitalization 6/29/2010 84 Female 9/1/2010 Other Health Professional France
Primary
Concomitant
Diverticulum Hospitalization 3/14/2010 78 Female 194 lb 9/1/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/21/2010 25 Female 9/1/2010 Consumer India
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 2/16/2009 56 Male 118 lb 9/13/2010 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 6/21/2010 25 Female 9/20/2010 Consumer India
Primary
Secondary
Concomitant
Diverticulum Hospitalization 3/14/2010 78 Female 202 lb 10/6/2010 Physician United States
Primary
Secondary
Concomitant
Renal Mass Life Threatening 7/10/2010 83 Female 10/6/2010 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 1/1/2008 88 Female 143 lb 10/11/2010 Consumer Brazil
Primary
Concomitant
Renal Mass Life Threatening 7/10/2010 83 Female 10/12/2010 Physician United States
Primary
Concomitant
Renal Impairment Disability 8/23/2010 73 Female 93 lb 10/13/2010 Physician Japan
Primary
Concomitant
Thrombosis Hospitalization 1/1/2008 88 Female 143 lb 10/14/2010 Consumer Brazil
Primary
Concomitant
Nephrolithiasis Hospitalization 3/14/2010 78 Female 202 lb 10/14/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/21/2010 25 Female 10/14/2010 Consumer India
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2008 88 Female 143 lb 10/19/2010 Consumer Brazil
Primary
Concomitant
Pruritus Female 158 lb 10/21/2010 Consumer United States
Primary
Concomitant
Renal Mass Life Threatening 7/10/2010 83 Female 10/26/2010 Physician United States
Primary
Concomitant
Renal Impairment Disability 8/23/2010 73 Female 93 lb 11/2/2010 Physician Japan
Primary
Concomitant
Myocardial Ischaemia Death 2/16/2009 56 Male 118 lb 11/11/2010 Physician Japan
Primary
Concomitant
Diarrhoea 1/1/2008 55 Female 11/18/2010 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 4/19/2010 81 Female 91 lb 11/22/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 11/9/2010 76 Female 11/25/2010 United States
Primary
Concomitant
Insomnia Hospitalization 8/5/2008 80 Female 86 lb 12/22/2010 Physician Japan
Primary
Concomitant
Death Death Female 92 lb 12/29/2010 Physician United States
Primary
Concomitant
Stress Urinary Incontinence Hospitalization 4/26/2008 85 Female 100 lb 1/13/2011 Lawyer United States
Primary
Concomitant
Pruritus Female 158 lb 1/21/2011 Consumer United States
Primary
Concomitant
Transaminases Increased Other Serious 1/5/2011 58 Female 2/8/2011 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 6/24/2008 71 Female 117 lb 2/11/2011 Consumer Canada
Primary
Secondary
Concomitant
Drug Interaction Other Serious 9/15/2010 70 Female 2/10/2011 Consumer United States
Primary
Concomitant
Anaemia Hospitalization 6/21/2010 25 Female 2/11/2011 Other Health Professional India
Primary
Secondary
Concomitant
Pneumonia Necrotising Hospitalization 6/24/2008 71 Female 117 lb 2/22/2011 Consumer Canada
Primary
Secondary
Concomitant
Insomnia Other Serious 8/5/2008 80 Female 86 lb 3/15/2011 Physician Japan
Primary
Concomitant
Urosepsis Hospitalization 3/14/2010 78 Female 202 lb 4/4/2011 Physician United States
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 8/5/2008 80 Female 86 lb 4/8/2011 Physician Japan
Primary
Concomitant
Hepatic Enzyme Increased Death 6/4/2007 64 Male 139 lb 3/30/2011 Physician Japan
Primary
Secondary
Concomitant
Hypotension Hospitalization 3/14/2010 78 Female 202 lb 4/18/2011 Physician United States
Primary
Secondary
Concomitant

Drug Data