Alendronate Sodium combined with Lansoprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Osteonecrosis Other Serious 7/18/2005 41 Female 1/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatomegaly Hospitalization 3/23/2005 46 Female 1/12/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Septic Shock Other Serious 3/1/2005 Female 1/20/2006 Physician United Kingdom
Primary
Concomitant
Pruritus Death 7/22/2004 Male 187 lb 1/25/2006 United Kingdom
Primary
Concomitant
Sepsis Hospitalization 1/1/2005 Male 225 lb 1/27/2006 Physician United Kingdom
Primary
Concomitant
Osteoarthritis Other Serious 8/1/2005 Female 135 lb 1/27/2006 United States
Primary
Concomitant
Lumbar Spinal Stenosis Other Serious 5/19/2005 Female 119 lb 2/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Life Threatening 51 Female 146 lb 1/31/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Osteoporosis Hospitalization 2/15/2004 Female 112 lb 2/9/2006 United Kingdom
Primary
Concomitant
Rash Life Threatening 11/13/2005 45 Female 140 lb 2/7/2006 United States
Primary
Concomitant
Pyrexia Hospitalization 8/25/2005 Male 2/15/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 11/10/2005 Male 121 lb 2/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Peritoneal Tuberculosis Hospitalization 71 Female 3/7/2006 United Kingdom
Primary
Secondary
Concomitant
Methaemoglobinaemia Hospitalization 1/1/2005 32 Female 3/29/2006 Physician United States
Primary
Secondary
Concomitant
Migraine Other Serious 7/7/2004 Female 152 lb 4/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
False Positive Laboratory Result Hospitalization 8/25/2005 Male 4/12/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/20/2006 58 Male 128 lb 4/13/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 11/1/2005 Male 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Spasms Hospitalization Male 4/28/2006 Physician United States
Primary
Concomitant
Rash Required Intervention 11/13/2005 45 Female 140 lb 5/2/2006 United States
Primary
Concomitant
Osteoporosis Hospitalization 2/15/2004 Female 112 lb 5/23/2006 Consumer United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 6/5/2006 Female 353 lb 6/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Haemorrhage Hospitalization 5/17/2006 Female 180 lb 6/21/2006 Consumer Canada
Primary
Concomitant
Completed Suicide Death 3/27/2006 Male 165 lb 6/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Intestinal Mass Other Serious 4/2/2006 Male 155 lb 6/27/2006 Physician United States
Primary
Concomitant
Fall Hospitalization 5/22/2006 85 Female 6/29/2006 Other Health Professional United Kingdom
Primary
Concomitant
Diabetes Mellitus Non-insulin-dependent Hospitalization 3/6/2006 Female 353 lb 7/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Diabetes Mellitus Non-insulin-dependent Hospitalization 3/6/2006 Female 353 lb 8/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 3/6/2006 Female 353 lb 8/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 100 8/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 3/6/2006 Female 353 lb 8/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Spasms Hospitalization Male 8/25/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2004 80 Female 90 lb 8/25/2006 Physician Japan
Primary
Concomitant
Pulmonary Fibrosis Death Female 123 lb 10/13/2006 Consumer United Kingdom
Primary
Concomitant
Respiratory Disorder Other Serious 42 Male 11/6/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Ischaemia Death Female 163 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hemiparesis Other Serious 5/3/2006 Female 192 lb 11/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Prurigo Hospitalization 9/1/2006 Female 121 lb 11/17/2006 Italy
Primary
Concomitant
Hemiparesis Other Serious 5/3/2006 Female 192 lb 11/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Infection Hospitalization 9/1/2006 Female 121 lb 11/28/2006 Italy
Primary
Concomitant
Toe Operation Other Serious 11/8/2006 Female 180 lb 12/1/2006 Consumer Canada
Primary
Concomitant
Rectal Haemorrhage Death 9/13/2006 Female 163 lb 12/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 42 Male 12/4/2006 United Kingdom
Primary
Secondary
Concomitant
Tibia Fracture Other Serious 11/9/2005 Female 159 lb 12/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Serotonin Syndrome Other Serious 55 Female 12/22/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 77 Male 12/27/2006 France
Primary
Concomitant
Pneumonia Other Serious 7/5/2006 152 lb 1/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Eczema Hospitalization 9/1/2006 Female 121 lb 1/19/2007 Italy
Primary
Concomitant
Rectal Haemorrhage Death 9/13/2006 Female 163 lb 1/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Death Other Serious 1/17/2007 Female 192 lb 1/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hypoaesthesia Hospitalization 11/1/2006 Female 150 lb 2/6/2007 Consumer United States
Primary
Concomitant
Ankle Fracture Hospitalization 8/17/2004 Female 112 lb 2/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 7/5/2006 152 lb 2/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Colic Hospitalization 11/5/2006 Male 176 lb 2/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hypoaesthesia Hospitalization 11/1/2006 Female 150 lb 2/14/2007 Physician United States
Primary
Concomitant
Interstitial Lung Disease Other Serious 74 Female 2/16/2007 Pharmacist Japan
Primary
Concomitant
Thrombocytopenia Other Serious 65 Female 2/12/2007 United States
Primary
Concomitant
Drug Level Increased Hospitalization 12/3/2006 Male 138 lb 2/23/2007 Pharmacist Japan
Primary
Concomitant
Interacting
Vasculitis Hospitalization 12/1/2005 Female 132 lb 3/8/2007 Consumer United Kingdom
Primary
Concomitant
Refractory Anaemia Other Serious 65 Female 3/20/2007 Other Health Professional United States
Primary
Concomitant
Lymphocytosis Hospitalization 11/17/2005 Female 3/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Osteoarthritis Hospitalization 3/12/2007 Female 120 lb 3/29/2007 Consumer Canada
Primary
Concomitant
Eczema Hospitalization 9/1/2006 Female 121 lb 3/30/2007 Italy
Primary
Concomitant
Cerebrovascular Accident Other Serious Female 192 lb 4/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 3/15/2007 70 Female 4/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 3/15/2007 70 Female 5/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hypochromic Anaemia Hospitalization 9/1/2006 Female 121 lb 5/16/2007 Italy
Primary
Concomitant
Bursitis Hospitalization 5/14/2007 Female 121 lb 5/25/2007 Italy
Primary
Concomitant
Vitreous Floaters Other Serious 10/11/2006 63 Female 120 lb 2/23/2007 United States
Primary
Concomitant
Hypertensive Crisis Hospitalization 3/14/2007 76 Female 132 lb 6/6/2007 Physician Austria
Primary
Concomitant
Osteoarthritis Other Serious 10/20/2001 71 Female 156 lb 6/6/2007 Physician United Kingdom
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 5/15/2007 Female 108 lb 6/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Bursitis Hospitalization 5/14/2007 Female 121 lb 6/27/2007 Italy
Primary
Concomitant
Amnesia Hospitalization 12/19/2006 Female 6/13/2007 Consumer United States
Primary
Concomitant
Bursitis Hospitalization 5/14/2007 Female 121 lb 7/12/2007 Italy
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 3/6/2006 Female 353 lb 7/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 7/5/2006 Male 152 lb 7/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Colic Other Serious 11/5/2006 Male 176 lb 7/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 11/15/2006 Female 269 lb 7/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bursitis Infective Hospitalization 5/14/2007 Female 121 lb 8/10/2007 Italy
Primary
Concomitant
Osteoarthritis Hospitalization 3/12/2007 Female 120 lb 8/10/2007 Consumer Canada
Primary
Concomitant
Rib Fracture Hospitalization 7/18/2007 76 Female 238 lb 8/31/2007 Consumer United Kingdom
Primary
Concomitant
Asthma Hospitalization 3/19/2007 Female 9/4/2007 Pharmacist Switzerland
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 9/6/2007 Consumer United Kingdom
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 5/15/2007 Female 108 lb 9/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 9/18/2007 Physician United Kingdom
Primary
Concomitant
Refractory Anaemia Other Serious 1/1/2005 65 Female 9/19/2007 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 8/29/2007 52 Female 321 lb 9/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pleurisy Hospitalization 5/9/2007 Male 214 lb 10/11/2007 United Kingdom
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 10/12/2007 Physician United Kingdom
Primary
Concomitant
Hepatitis B Virus Other Serious 7/5/2007 72 Male 134 lb 10/31/2007 Physician Japan
Primary
Concomitant
Myocardial Ischaemia Other Serious Male 168 lb 12/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Viral Infection Hospitalization 12/20/2006 Male 146 lb 12/7/2007 United Kingdom
Primary
Concomitant
Pericardial Effusion Malignant Death 9/10/2005 76 Female 84 lb 12/11/2007 Japan
Primary
Concomitant
Basal Cell Carcinoma Other Serious 12/12/2006 Female 137 lb 12/19/2007 Physician United Kingdom
Primary
Concomitant
Asthma Other Serious 7/5/2007 72 Male 134 lb 12/28/2007 Physician Japan
Primary
Concomitant
Amnesia Hospitalization 12/19/2006 66 Female 148 lb 12/11/2007 United States
Primary
Concomitant
Malaise Hospitalization 7/2/2007 Male 1/21/2008 United Kingdom
Primary
Concomitant
Vitrectomy Other Serious 6/25/2007 Female 161 lb 2/1/2008 United Kingdom
Primary
Concomitant
Vitrectomy Other Serious 6/25/2007 Female 161 lb 2/1/2008 United Kingdom
Primary
Concomitant
Rash Hospitalization 7/1/2004 77 Female 127 lb 11/29/2007 Consumer United States
Primary
Concomitant
Pancreatitis Acute Life Threatening 10/1/2007 Female 150 lb 2/15/2008 Physician Japan
Primary
Concomitant
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/15/2008 Consumer United Kingdom
Primary
Secondary
Factor Viii Deficiency Other Serious 12/15/2007 Female 117 lb 2/22/2008 United Kingdom
Primary
Concomitant
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/22/2008 United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/27/2008 United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Sepsis Other Serious 7/9/2007 Female 161 lb 3/3/2008 United Kingdom
Primary
Concomitant
Toxic Skin Eruption 1/2/2008 72 Male 3/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 3/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Streptococcal Sepsis Other Serious 4/1/2007 Female 190 lb 3/7/2008 United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Acute Life Threatening 10/30/2007 Female 150 lb 3/11/2008 Physician Japan
Primary
Concomitant
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 3/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Sinus Congestion 1/17/2008 Female 3/15/2008 United States
Primary
Concomitant
Rash Hospitalization 11/13/2007 Male 4/18/2008 Physician Japan
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Other Serious 2/26/2008 Female 4/24/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 4/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Other Serious 2/26/2008 Female 4/30/2008 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 82 Female 5/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 82 Female 4/30/2008 United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 82 Female 5/2/2008 United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Other Serious 82 Female 5/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Hospitalization 7/2/2007 Male 5/30/2008 United Kingdom
Primary
Concomitant
Glomerulonephritis Membranous Hospitalization 1/1/2008 Male 99 lb 6/4/2008 Physician Japan
Primary
Concomitant
Lower Limb Fracture Hospitalization 12/22/2007 Female 134 lb 6/9/2008 United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 6/2/2000 51 Female 6/18/2008 United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Other Serious 12/15/2007 Female 117 lb 6/24/2008 United Kingdom
Primary
Concomitant
Rash Hospitalization 11/13/2007 Male 6/27/2008 Physician Japan
Primary
Concomitant
Surgery Other Serious 12/1/2003 Female 106 lb 6/30/2008 United States
Primary
Concomitant
Somnolence Other Serious 7/10/2008 60 Male 7/21/2008 Physician Guatemala
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 7/2/2008 82 Female 7/25/2008 Physician Japan
Primary
Concomitant
Tuberculous Pleurisy Hospitalization 4/1/2007 Female 130 lb 8/1/2008 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 4/22/2008 Female 181 lb 8/8/2008 United Kingdom
Primary
Concomitant
Neuropathy Peripheral Other Serious 7/12/2008 39 Male 218 lb 8/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Death 9/1/2007 Male 8/11/2008 Consumer Ireland
Primary
Concomitant
International Normalised Ratio Decreased Other Serious Female 8/28/2008
Primary
Secondary
Concomitant
Pruritus 5/1/2008 Female 222 lb 8/29/2008 Consumer United States
Primary
Concomitant
Pruritus 7/6/2008 Female 8/29/2008 United States
Primary
Concomitant
Renal Failure Hospitalization 1/3/2006 51 Female 8/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Dyskinesia Other Serious 5/4/2008 Male 125 lb 9/5/2008 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 75 Female 9/12/2008 Other Health Professional United States
Primary
Concomitant
Interacting
Skin Tightness 7/1/2008 Female 256 lb 9/12/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 7/23/2008 Female 9/12/2008 United States
Primary
Concomitant
Tinnitus Hospitalization 6/1/2008 Female 140 lb 9/13/2008 Other Health Professional United States
Primary
Concomitant
Device Related Infection Hospitalization 5/5/2008 Female 9/17/2008 Consumer United Kingdom
Primary
Concomitant
Interstitial Lung Disease Life Threatening 8/6/2008 Female 9/19/2008 Pharmacist Japan
Primary
Concomitant
Serotonin Syndrome Other Serious 8/28/2008 Female 10/1/2008 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 8/6/2008 Female 10/6/2008 Physician Japan
Primary
Concomitant
Interacting
Prostatitis Hospitalization 9/1/2008 Male 143 lb 10/7/2008 Physician Japan
Primary
Secondary
Concomitant
Encephalitis Hospitalization 5/13/2008 Female 170 lb 10/8/2008 United Kingdom
Primary
Concomitant

Drug Data