Alendronate Sodium combined with Isoniazid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rash Hospitalization 11/7/2005 Female 1/11/2006 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Other Serious 3/1/2005 Female 1/20/2006 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 8/25/2005 Male 2/15/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 11/10/2005 Male 121 lb 2/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
False Positive Laboratory Result Hospitalization 8/25/2005 Male 4/12/2006 Physician Japan
Primary
Secondary
Concomitant
Vasculitis Other Serious 11/15/2005 Female 111 lb 9/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 54 Female 11/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urticaria Hospitalization 12/28/2006 Male 1/30/2007 Physician Germany
Primary
Secondary
Concomitant
Erythema Multiforme Hospitalization 8/25/2005 63 Male 6/1/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 54 Female 5/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vasculitis Other Serious 11/15/2005 Female 111 lb 8/6/2007 Physician United Kingdom
Primary
Concomitant
Multiple Fractures Hospitalization 3/5/2004 Female 146 lb 12/7/2007 United Kingdom
Primary
Concomitant
Joint Contracture 3/13/2008 Female 186 lb 6/12/2008 Consumer United States
Primary
Concomitant
Pneumonia Mycoplasmal Hospitalization 5/15/2008 Female 93 lb 7/21/2008 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 7/10/2008 Female 104 lb 7/25/2008 Physician Japan
Primary
Secondary
Concomitant
Tuberculous Pleurisy Hospitalization 4/1/2007 Female 130 lb 8/1/2008 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 7/10/2008 Female 104 lb 8/5/2008 Physician Japan
Primary
Secondary
Concomitant
Injection Site Pain 1/1/2008 Female 191 lb 9/12/2008 Consumer United States
Primary
Concomitant
Enterocolitis Bacterial Hospitalization 12/9/2008 Female 79 lb 1/28/2009 Japan
Primary
Concomitant
Gait Disturbance Hospitalization 11/5/2008 Female 121 lb 4/24/2009 Japan
Primary
Concomitant
Gait Disturbance Hospitalization 11/5/2008 Female 121 lb 5/1/2009 Japan
Primary
Concomitant
Enterocolitis Bacterial Hospitalization 12/3/2008 Female 79 lb 6/3/2009 Japan
Primary
Concomitant
Paralysis Hospitalization 12/12/2008 Female 140 lb 6/9/2009 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/28/2009 61 Female 6/11/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/28/2009 61 Female 111 lb 6/19/2009 Consumer Japan
Primary
Secondary
Concomitant
Ligament Injury Hospitalization 5/14/2009 6/30/2009 Japan
Primary
Concomitant
Vomiting Hospitalization 5/28/2009 61 Female 111 lb 7/6/2009 Physician Japan
Primary
Secondary
Concomitant
Ligament Injury Hospitalization 5/14/2009 7/15/2009 Japan
Primary
Concomitant
Enterocolitis Bacterial Hospitalization 12/3/2008 Female 79 lb 7/30/2009 Japan
Primary
Concomitant
Enterocolitis Bacterial Hospitalization 12/3/2008 Female 79 lb 8/4/2009 Japan
Primary
Concomitant
Pneumonia Other Serious 7/25/2009 Female 150 lb 8/7/2009 Brazil
Primary
Concomitant
Pneumonia Other Serious 3/27/2009 Female 150 lb 9/3/2009 Brazil
Primary
Concomitant
Spondylolisthesis Hospitalization 8/27/2009 Female 121 lb 9/10/2009 Japan
Primary
Concomitant
Joint Contracture 3/13/2008 Female 186 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 1/1/2008 Female 191 lb 9/12/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 11/10/2007 78 Male 123 lb 9/17/2009 Consumer Japan
Primary
Concomitant
Paralysis Hospitalization 12/12/2008 Female 140 lb 9/25/2009 Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 5/25/2009 Female 82 lb 9/30/2009 Japan
Primary
Concomitant
Vomiting Hospitalization 5/28/2009 61 Female 111 lb 10/20/2009 Physician Japan
Primary
Secondary
Concomitant
Paralysis Hospitalization 12/12/2008 Female 140 lb 12/4/2009 Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 5/25/2009 Female 82 lb 12/4/2009 Japan
Primary
Concomitant
Ligament Injury Hospitalization 5/14/2009 12/9/2009 Japan
Primary
Concomitant
Pneumonia Hospitalization 6/26/2009 Female 2/2/2010 Physician Japan
Primary
Secondary
Concomitant
Spondylolisthesis Hospitalization 9/1/2009 Female 121 lb 2/5/2010 Japan
Primary
Concomitant
Liver Disorder Hospitalization 3/24/2009 Female 99 lb 2/9/2010 Physician Japan
Primary
Secondary
Concomitant
Spondylolisthesis Hospitalization 9/1/2009 Female 121 lb 3/9/2010 Japan
Primary
Concomitant
Vomiting Hospitalization 12/18/2009 Female 3/10/2010 Japan
Primary
Concomitant
Vomiting Hospitalization 5/28/2009 Female 111 lb 3/12/2010 Physician Japan
Primary
Concomitant
Pneumonia Primary Atypical Hospitalization 3/1/2010 65 Female 3/30/2010 Other Health Professional Japan
Primary
Concomitant
Pneumonia Pneumococcal Hospitalization 3/17/2010 65 Female 4/7/2010 Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 12/18/2009 68 Female 4/7/2010 Japan
Primary
Secondary
Concomitant
Urticaria Hospitalization 3/17/2010 65 Female 4/19/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 3/18/2010 86 Female 4/27/2010 Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 3/18/2010 86 Female 4/29/2010 Japan
Primary
Secondary
Concomitant
Productive Cough Hospitalization 3/19/2010 71 Female 75 lb 5/3/2010 Japan
Primary
Concomitant
Urticaria Hospitalization 3/17/2010 65 Female 4/27/2010 Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Hospitalization 3/19/2010 71 Female 75 lb 5/17/2010 Japan
Primary
Concomitant
Pneumonia Pneumococcal Hospitalization 12/18/2009 68 Female 5/10/2010 Japan
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 3/18/2010 86 Female 5/18/2010 Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Hospitalization 3/19/2010 71 Female 75 lb 5/19/2010 Japan
Primary
Concomitant
Urticaria Hospitalization 3/17/2010 65 Female 5/11/2010 Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 12/18/2009 68 Female 5/19/2010 Japan
Primary
Secondary
Concomitant
Urticaria Hospitalization 3/17/2010 65 Female 5/21/2010 Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Hospitalization 3/19/2010 71 Female 75 lb 5/28/2010 Japan
Primary
Concomitant
Metrorrhagia Hospitalization 5/19/2010 56 Female 6/1/2010 Japan
Primary
Concomitant
Endometrial Cancer Hospitalization 5/19/2010 56 Female 6/7/2010 Other Health Professional Japan
Primary
Concomitant
Pyrexia Other Serious 12/30/2009 72 Female 95 lb 6/14/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/30/2009 72 Female 95 lb 6/15/2010 Physician Japan
Primary
Secondary
Concomitant
Metrorrhagia Hospitalization 5/19/2010 56 Female 6/11/2010 Japan
Primary
Concomitant
Pyrexia Other Serious 12/30/2009 72 Female 95 lb 6/18/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/28/2009 61 Female 111 lb 6/10/2010 Physician Japan
Primary
Concomitant
Tuberculosis Hospitalization 2/17/2010 68 Male 119 lb 6/28/2010 Physician Japan
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 2/17/2010 68 Male 119 lb 6/30/2010 Physician Japan
Primary
Secondary
Concomitant
Endometriosis Hospitalization 5/19/2010 56 Female 7/1/2010 Japan
Primary
Concomitant
Vomiting Hospitalization 5/28/2009 61 Female 111 lb 7/1/2010 Physician Japan
Primary
Secondary
Concomitant
Endometriosis Hospitalization 5/19/2010 56 Female 7/1/2010 Japan
Primary
Concomitant
Uterine Leiomyoma Hospitalization 10/7/2009 56 Female 7/6/2010 Japan
Primary
Concomitant
Uterine Leiomyoma Hospitalization Female 8/10/2010 Japan
Primary
Concomitant
Tuberculosis Hospitalization 2/17/2010 68 Male 119 lb 8/18/2010 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 3/10/2010 72 Female 108 lb 8/25/2010 Physician Japan
Primary
Secondary
Concomitant
Periodontitis Hospitalization 11/9/2009 76 Male 8/27/2010 Physician Japan
Primary
Concomitant
Paralysis Hospitalization 12/12/2008 68 Female 140 lb 9/14/2010 Physician Japan
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 2/17/2010 68 Male 119 lb 9/14/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Disorder Death 4/15/2010 54 Male 132 lb 9/20/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/28/2009 61 Female 111 lb 9/22/2010 Physician Japan
Primary
Secondary
Concomitant
Streptococcus Test Positive Death 4/15/2010 54 Male 132 lb 10/4/2010 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 3/10/2010 72 Female 108 lb 10/7/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/28/2009 61 Female 111 lb 10/5/2010 Consumer Japan
Primary
Secondary
Concomitant
Uterine Leiomyoma Hospitalization 5/19/2010 56 Female 10/20/2010 Other Health Professional Japan
Primary
Concomitant
Breast Cancer Female Life Threatening 4/8/2010 12/6/2010 Physician Japan
Primary
Concomitant
Urosepsis Hospitalization 5/28/2009 61 Female 111 lb 12/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Uterine Leiomyoma Other Serious 5/19/2010 56 Female 12/22/2010 Japan
Primary
Secondary
Concomitant
Computerised Tomogram Abnormal Hospitalization 2/17/2010 68 Male 119 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Joint Stiffness Hospitalization 2/17/2010 68 Male 119 lb 1/14/2011 Physician Japan
Primary
Secondary
Concomitant
Cough Other Serious 11/1/2002 51 Female 1/18/2011 Physician United States
Primary
Secondary
Concomitant
Arthralgia Hospitalization 2/17/2010 68 Male 119 lb 2/18/2011 Physician Japan
Primary
Secondary
Concomitant
Chest X-ray Abnormal Hospitalization 2/17/2010 68 Male 119 lb 2/23/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 10/30/2010 75 Female 2/24/2011 Physician Japan
Primary
Concomitant
Pneumonia Bacterial Hospitalization 3/19/2010 71 Female 75 lb 3/3/2011 Physician Japan
Primary
Concomitant
Hepatitis C Other Serious 10/30/2010 75 Female 3/17/2011 Physician Japan
Primary
Concomitant
Uterine Leiomyoma Other Serious 5/19/2010 56 Female 3/9/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Joint Stiffness Hospitalization 2/17/2010 68 Male 119 lb 3/25/2011 Physician Japan
Primary
Secondary
Concomitant
Immunosuppression Hospitalization 8/20/2010 72 Female 119 lb 3/30/2011 Physician Japan
Primary
Secondary
Concomitant
Lymphadenopathy Hospitalization 5/1/2010 63 Male 120 lb 4/5/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Arthralgia Hospitalization 11/29/2010 86 Female 75 lb 4/5/2011 Physician Japan
Primary
Secondary
Concomitant
Cataract Hospitalization 5/19/2010 56 Female 3/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Sudden Hearing Loss Other Serious 3/25/2011 38 Female 5/13/2011 Physician Japan
Primary
Concomitant
Sudden Hearing Loss Other Serious 3/25/2011 38 Female 117 lb 5/23/2011 Physician Japan
Primary
Concomitant
Post Herpetic Neuralgia Other Serious 1/1/2008 80 Male 134 lb 5/25/2011 Physician Japan
Primary
Secondary
Concomitant
Post Herpetic Neuralgia Other Serious 1/1/2008 80 Male 134 lb 5/26/2011 Physician Japan
Primary
Secondary
Concomitant
Pseudomonas Infection Other Serious 3/29/2011 60 Male 128 lb 6/9/2011 Physician Japan
Primary
Secondary
Concomitant
Corneal Graft Rejection Disability 6/21/2009 75 Female 6/16/2011 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 2/19/2009 61 Female 134 lb 6/17/2011 Physician Japan
Primary
Concomitant
Dizziness Other Serious 3/25/2011 38 Female 117 lb 6/21/2011 Physician Japan
Primary
Concomitant
Oxygen Saturation Decreased Life Threatening 6/29/2011 38 Female 117 lb 7/1/2011 Physician Japan
Primary
Concomitant
Nausea Other Serious 3/25/2011 38 Female 117 lb 7/1/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Infection Other Serious 8/20/2010 72 Female 119 lb 7/8/2011 Physician Japan
Primary
Secondary
Concomitant
Tinnitus Other Serious 3/25/2011 38 Female 112 lb 7/21/2011 Physician Japan
Primary
Concomitant
Myelitis Hospitalization 1/1/2009 59 Female 154 lb 7/25/2011 Physician Japan
Primary
Concomitant
Rash Generalised Other Serious 6/25/2011 38 Female 112 lb 7/25/2011 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 1/20/2010 77 Female 93 lb 7/25/2011 Physician Japan
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 10/10/2010 74 Female 101 lb 7/26/2011 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 11/5/2010 73 Female 127 lb 7/11/2011 Physician
Primary
Secondary
Concomitant
Myelitis Other Serious 1/1/2009 59 Female 154 lb 8/1/2011 Physician Japan
Primary
Concomitant
Rash Generalised Life Threatening 5/25/2011 38 Female 112 lb 8/8/2011 Physician Japan
Primary
Concomitant
Dizziness Other Serious 3/25/2011 38 Female 112 lb 8/8/2011 Physician Japan
Primary
Concomitant
Tachycardia Other Serious 3/1/2010 70 Female 86 lb 8/10/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Rash Generalised Life Threatening 5/25/2011 38 Female 112 lb 8/25/2011 Physician Japan
Primary
Concomitant
Dizziness Other Serious 3/25/2011 38 Female 112 lb 8/30/2011 Physician Japan
Primary
Concomitant
Lacunar Infarction Hospitalization 6/12/2011 74 Female 92 lb 9/8/2011 Physician Japan
Primary
Secondary
Concomitant
Back Pain Hospitalization 2/17/2010 68 Male 119 lb 9/15/2011 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Death 4/15/2010 54 Male 132 lb 9/21/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 7/4/2011 72 Female 9/21/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 8/22/2010 70 Female 9/23/2011 Physician Japan
Primary
Concomitant
Lacunar Infarction Hospitalization 6/12/2011 74 Female 92 lb 10/3/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 7/4/2011 72 Female 10/3/2011 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Death 4/15/2010 54 Male 132 lb 10/7/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 7/4/2011 72 Female 10/12/2011 Physician Japan
Primary
Secondary
Concomitant
Respiratory Disorder Death 4/15/2010 54 Male 132 lb 10/17/2011 Physician Japan
Primary
Secondary
Concomitant
Sputum Purulent Hospitalization 3/1/2010 83 Female 102 lb 10/19/2011 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 1/20/2011 61 Male 97 lb 10/24/2011 Physician Japan
Primary
Secondary
Concomitant
Sputum Increased Hospitalization 3/1/2010 83 Female 102 lb 10/27/2011 Physician Japan
Primary
Concomitant
Haemoptysis Other Serious 2/19/2009 76 Female 11/7/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 3/1/2010 70 Female 86 lb 12/8/2011 Japan
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Hospitalization 1/1/2011 69 Male 132 lb 12/12/2011 Physician Japan
Primary
Concomitant
Lumbar Spinal Stenosis Other Serious 2/19/2009 76 Female 12/14/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 2/5/2011 86 Female 12/19/2011 Consumer Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 4/14/2011 32 Female 110 lb 12/23/2011 Consumer Japan
Primary
Secondary
Concomitant
Insomnia Other Serious 11/17/2009 66 Female 110 lb 12/27/2011 Physician Japan
Primary
Concomitant
Epstein-barr Virus Infection Hospitalization 1/1/2011 69 Male 132 lb 12/30/2011 Physician Japan
Primary
Concomitant

Drug Data