Alendronate Sodium combined with Hydrochlorothiazide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Erythema Hospitalization 11/1/2005 Female 2/15/2006 Germany
Primary
Concomitant
Syncope Hospitalization 11/10/2005 Female 2/21/2006 Pharmacist United States
Primary
Concomitant
Knee Arthroplasty Hospitalization 2/28/2006 Female 3/24/2006 Consumer Canada
Primary
Concomitant
Erythema Hospitalization 11/1/2005 Female 3/28/2006 Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 3/14/2006 72 Male Pharmacist United States
Primary
Secondary
Concomitant
Angioneurotic Oedema Life Threatening 6/9/2006 72 Female 144 lb 6/14/2006 Other Health Professional United States
Primary
Concomitant
Oesophagitis Hospitalization 4/23/2006 84 Male 137 lb 7/23/2006 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 2/1/2003 Female 178 lb 7/26/2006 Consumer United States
Primary
Concomitant
Bone Density Decreased Other Serious 84 Female 97 lb 8/1/2006 Physician United States
Primary
Concomitant
Visual Disturbance Life Threatening 1/1/2004 83 Female 8/10/2006 Physician Germany
Primary
Concomitant
Transplant Rejection Hospitalization 4/17/2006 55 Male 261 lb 5/10/2006 Pharmacist United States
Primary
Concomitant
Sepsis Other Serious 10/16/2003 Female 121 lb 9/1/2006 Physician United States
Primary
Concomitant
Ventricular Arrhythmia Life Threatening 2/22/2006 Female 9/21/2006 Physician Germany
Primary
Concomitant
Vestibular Disorder Hospitalization 9/19/2006 57 Male 269 lb 10/6/2006 Other Health Professional United States
Primary
Concomitant
Sedation Hospitalization 9/19/2006 57 Male 269 lb 10/9/2006 Other Health Professional United States
Primary
Concomitant
Restless Legs Syndrome Hospitalization 9/19/2006 57 Male 269 lb 10/23/2006 Other Health Professional United States
Primary
Concomitant
Cervical Vertebral Fracture Hospitalization Female 100 lb 11/22/2006 Consumer Canada
Primary
Concomitant
Viral Infection Hospitalization 9/19/2006 57 Male 269 lb 11/10/2006 Other Health Professional United States
Primary
Concomitant
Erythema Hospitalization 11/1/2005 Female 12/26/2006 Germany
Primary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 1/8/2007
Primary
Secondary
Concomitant
Infection Hospitalization Female 100 lb 1/17/2007 Consumer Canada
Primary
Concomitant
Vomiting Other Serious 10/16/2003 Female 121 lb 2/12/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 10/16/2003 Female 121 lb 2/16/2007 Physician United States
Primary
Concomitant
Plasma Cells Increased Other Serious 12/1/2006 74 Male 2/13/2007 Physician United States
Primary
Secondary
Concomitant
Plasma Cells Increased Other Serious 12/1/2006 74 Male 2/28/2007 Physician United States
Primary
Secondary
Concomitant
Eosinophilia Hospitalization 11/1/2005 Female 3/2/2007 Germany
Primary
Concomitant
Respiratory Failure Hospitalization 2/9/2007 Female 101 lb 3/15/2007 Brazil
Primary
Concomitant
Yellow Skin Hospitalization 3/16/2007 81 Male 134 lb 3/29/2007 Pharmacist United States
Primary
Concomitant
Multi-organ Failure Hospitalization 2/21/2007 Female 101 lb 4/6/2007 Brazil
Primary
Concomitant
Syncope Other Serious 5/14/2007 76 Female 6/15/2007 Canada
Primary
Concomitant
Hip Arthroplasty Hospitalization 6/20/2007 Female 110 lb 7/18/2007 Canada
Primary
Concomitant
Yawning Other Serious 3/1/2007 Female 122 lb 7/23/2007 Physician United States
Primary
Concomitant
Hip Arthroplasty Hospitalization 6/20/2007 Female 110 lb 7/30/2007 Canada
Primary
Concomitant
Eosinophilia Hospitalization 11/1/2005 Female 8/10/2007 Germany
Primary
Concomitant
Multi-organ Failure Hospitalization 2/21/2007 Female 101 lb 9/10/2007 Brazil
Primary
Concomitant
Visual Disturbance Hospitalization 8/28/2007 73 Female 256 lb 9/19/2007 Consumer Brazil
Primary
Secondary
Concomitant
Blood Glucose Decreased Hospitalization 4/15/2007 75 Male 8/22/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 8/9/2007 58 Male 206 lb 9/28/2007 Consumer United States
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 9/10/2007 72 Female 194 lb 10/9/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/9/2007 58 Male 206 lb 10/3/2007 Consumer United States
Primary
Secondary
Concomitant
Skin Discolouration Hospitalization 9/25/2007 53 Male 10/26/2007 Consumer Brazil
Primary
Secondary
Concomitant
Pruritus Hospitalization 9/29/2007 79 Female 139 lb 11/28/2007 Pharmacist United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 9/10/2007 72 Female 194 lb 12/6/2007 Physician United States
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 2/9/2007 Female 101 lb 12/17/2007 Brazil
Primary
Concomitant
Pulmonary Embolism Life Threatening 1/26/2008 Male 97 lb 2/8/2008 United States
Primary
Concomitant
Renal Failure Hospitalization 1/1/2008 61 Female 169 lb 2/25/2008 France
Primary
Secondary
Concomitant
Viral Infection Other Serious 1/9/2008 Female 154 lb 3/13/2008 Consumer Brazil
Primary
Concomitant
Pulmonary Embolism Life Threatening 1/26/2008 Male 97 lb 4/4/2008 United States
Primary
Concomitant
Social Avoidant Behaviour Other Serious 79 Female 5/9/2008 United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 1/26/2008 Male 97 lb 5/21/2008 United States
Primary
Concomitant
Pain 4/1/2008 66 Female 6/24/2008 Consumer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 5/19/2008 80 Female 116 lb 6/30/2008 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral 4/1/2008 69 Female 148 lb 7/30/2008 Physician United States
Primary
Concomitant
Alopecia 1/1/2003 Female 118 lb 9/12/2008 Physician United States
Primary
Concomitant
Injection Site Irritation 6/27/2008 Female 165 lb 9/12/2008 United States
Primary
Concomitant
Muscle Atrophy Other Serious 59 Female 10/23/2008 Consumer United States
Primary
Concomitant
Myalgia 9/1/2008 Female 11/26/2008 United States
Primary
Concomitant
Injection Site Pain 5/1/2008 Female 115 lb 12/12/2008 Consumer United States
Primary
Concomitant
Vision Blurred 8/1/2007 Male 250 lb 12/12/2008 Consumer United States
Primary
Secondary
Concomitant
Bicytopenia Other Serious 11/25/2008 Male 192 lb 12/18/2008 Physician Canada
Primary
Concomitant
Pruritus Other Serious 12/15/2008 66 Female 150 lb 1/7/2009 Other Health Professional United States
Primary
Concomitant
Myelofibrosis Other Serious 11/25/2008 Male 192 lb 1/26/2009 Physician Canada
Primary
Concomitant
Salivary Hypersecretion 12/27/2008 Female 2/9/2009 Consumer
Primary
Concomitant
Platelet Count Decreased Other Serious Female 2/11/2009 Consumer United States
Primary
Concomitant
Myelofibrosis Other Serious 11/25/2008 Male 192 lb 2/17/2009 Physician Canada
Primary
Concomitant
Salivary Hypersecretion 12/27/2008 Female 2/20/2009 Consumer
Primary
Concomitant
Platelet Count Decreased Other Serious Female 161 lb 2/26/2009 Physician United States
Primary
Concomitant
Cough 12/1/2008 79 Male 3/2/2009 Consumer
Primary
Secondary
Concomitant
Speech Disorder 9/20/2008 Female 3/12/2009 Consumer United States
Primary
Concomitant
Weight Decreased Life Threatening 75 Female 183 lb 3/16/2009 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/5/2009 Male 141 lb 3/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 75 Female 183 lb 3/13/2009 Pharmacist United States
Primary
Secondary
Concomitant
Myalgia Other Serious 77 Female 3/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Cough 12/1/2008 79 Male 4/3/2009 Consumer
Primary
Secondary
Concomitant
Stomatitis Disability 75 Female 4/2/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 75 Female 183 lb 4/2/2009 Pharmacist United States
Primary
Secondary
Concomitant
Myelofibrosis Other Serious 11/25/2008 Male 192 lb 4/16/2009 Physician Canada
Primary
Concomitant
Breast Cancer Female Other Serious 7/9/2001 Female 119 lb 4/17/2009 United States
Primary
Secondary
Concomitant
Urine Analysis Abnormal Other Serious 8/20/2008 Male 169 lb 4/20/2009 United States
Primary
Concomitant
Product Substitution Issue Other Serious 2/13/2009 Female 135 lb 4/10/2009 Other Health Professional United States
Primary
Concomitant
Nausea Other Serious 12/18/2008 Female 119 lb 6/29/2009 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Other Serious 75 Female 183 lb 7/13/2009 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 75 Female 183 lb 8/12/2009 Pharmacist United States
Primary
Secondary
Concomitant
Exostosis Hospitalization 1/1/2009 46 Female 8/21/2009 Consumer Germany
Primary
Secondary
Concomitant
Joint Swelling 8/1/2008 Female 8/21/2009 United States
Primary
Concomitant
Flushing Female 118 lb 8/22/2009 United States
Primary
Concomitant
Gastrooesophageal Reflux Disease 6/1/2009 Female 160 lb 8/22/2009 United States
Primary
Concomitant
Incorrect Dose Administered 10/12/2006 Female 132 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 1/2/2007 Female 138 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 4/23/2007 Female 98 lb 9/11/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 5/1/2008 Female 115 lb 9/12/2009 Consumer United States
Primary
Concomitant
Osteonecrosis Other Serious 5/1/2006 68 Female 9/4/2009 Physician United States
Primary
Concomitant
Eye Haemorrhage Other Serious 73 Female 168 lb 10/1/2009 Consumer United States
Primary
Concomitant
Prosthesis Implantation Other Serious Female 119 lb 10/8/2009 Brazil
Primary
Concomitant
Weight Increased Other Serious 4/19/2001 Female 11/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/19/2001 Female 11/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rib Fracture 6/17/2008 Female 194 lb 12/3/2009 Physician United States
Primary
Concomitant
Rheumatoid Arthritis 3/1/2009 Female 189 lb 12/8/2009 Physician United States
Primary
Concomitant
Fall 1/1/2009 81 Female 117 lb 12/23/2009 Consumer United States
Primary
Concomitant
Chromaturia 11/1/2009 Female 1/24/2010 Other Health Professional United States
Primary
Concomitant
Vomiting 12/4/2009 Female 1/24/2010 Consumer United States
Primary
Concomitant
Pseudomembranous Colitis Hospitalization 80 Female 1/19/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/19/2001 Female 2/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/19/2001 Female 2/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/19/2001 Female 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/6/2009 65 Female 170 lb 3/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/6/2009 65 Female 170 lb 3/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Injury Other Serious 12/1/2008 Female 3/19/2010 Consumer United States
Primary
Concomitant
Embolic Stroke Hospitalization 79 Female 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/6/2009 65 Female 170 lb 4/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumothorax Required Intervention 4/8/2010 72 Female 4/13/2010 Pharmacist United States
Primary
Concomitant
Hypokalaemia Hospitalization 11/6/2009 65 Female 170 lb 4/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 3/21/2010 81 Male 142 lb 4/26/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Septic Shock Life Threatening 4/4/2010 82 Female 5/7/2010 Physician United States
Primary
Concomitant
Hyponatraemia Hospitalization 3/21/2010 81 Male 142 lb 6/8/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Tremor Other Serious 2/2/2010 75 Male 160 lb 6/23/2010 Physician United States
Primary
Concomitant
Urinary Retention 11/1/2005 68 Female 130 lb 6/30/2010 Consumer United States
Primary
Secondary
Concomitant
Myelofibrosis Other Serious 11/25/2008 76 Male 192 lb 7/12/2010 Physician Canada
Primary
Concomitant
Urticaria Hospitalization Female 6/30/2010 United States
Primary
Concomitant
Sleep Disorder Other Serious 12/1/2007 64 Male 165 lb 7/17/2010 Other Health Professional United States
Primary
Concomitant
Thyroid Cancer Other Serious 2/27/2010 56 Female 252 lb 7/28/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 4/19/2001 62 Female 7/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Myalgia 1/11/2007 77 Female 108 lb 7/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea 5/13/2008 80 Female 140 lb 8/3/2010 Consumer United States
Primary
Concomitant
Pseudomembranous Colitis Hospitalization 80 Female 8/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Column Stenosis Other Serious 2/1/2007 65 Female 157 lb 8/11/2010 Consumer United States
Primary
Concomitant
Thyroid Cancer Other Serious 2/27/2010 56 Female 252 lb 8/11/2010 Other Health Professional United States
Primary
Concomitant
Prostate Cancer Recurrent Other Serious 1/1/2005 66 Male 180 lb 8/13/2010 Consumer United States
Primary
Concomitant
Rash Pruritic 8/3/2010 58 Female 205 lb 8/16/2010 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 8/13/2010 62 Female 206 lb 8/25/2010 Consumer United States
Primary
Secondary
Concomitant
Rash 8/1/2009 74 Female 145 lb 8/28/2010 United States
Primary
Concomitant
Muscle Spasms 2/8/2010 67 Female 155 lb 8/28/2010 United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/1/2010 Female 9/9/2010 Physician United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 9/9/2010 80 Female 134 lb 9/23/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Sensory Disturbance Other Serious 85 Female 150 lb 9/27/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2010 71 Male 138 lb 9/29/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2010 71 Male 138 lb 10/14/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 10/19/2010 Other Health Professional United States
Primary
Concomitant
Erythema 1/1/2010 Female 10/26/2010 Consumer United States
Primary
Concomitant
Respiratory Tract Infection 85 Female 10/13/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2008 80 Male 140 lb 11/4/2010 Physician United States
Primary
Concomitant
Somnolence 10/7/2010 69 Female 147 lb 11/6/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2010 82 Male 140 lb 11/8/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/13/2010 62 Female 206 lb 11/13/2010 Physician United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 9/9/2010 80 Female 134 lb 11/22/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Shock Life Threatening 11/11/2010 58 Female 150 lb 11/23/2010 Physician United States
Primary
Secondary
Concomitant
Injection Site Pain 12/15/2010 Consumer United States
Primary
Concomitant
Nausea 10/24/2010 69 Female 161 lb 12/17/2010 Consumer United States
Primary
Concomitant
Hypokalaemia Hospitalization 11/6/2009 65 Female 170 lb 12/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea 2/1/2010 12/22/2010 Other Health Professional United States
Primary
Concomitant

Drug Data