Alendronate Sodium combined with Fosamax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Confusional State Other Serious 81 Female 3/8/2006 Physician Ireland
Primary
Concomitant
Confusional State Other Serious 9/1/2005 81 Female 3/14/2006 Physician Ireland
Primary
Concomitant
Rhabdomyolysis Life Threatening 3/5/2003 52 Female 5/1/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 3/5/2003 52 Female 5/11/2006 Canada
Primary
Secondary
Concomitant
Calcinosis Other Serious 5/1/2005 50 Female 6/16/2006 Pharmacist Netherlands
Primary
Secondary
Thyroid Adenoma Hospitalization 2/1/2004 75 Female 130 lb 7/11/2006 Consumer United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 7/4/2006 53 Female 99 lb 8/18/2006 Physician Japan
Primary
Secondary
Concomitant
Petit Mal Epilepsy Other Serious 73 Female 132 lb 3/20/2007 Consumer Brazil
Primary
Concomitant
Hypokinesia 3/2/2007 73 Female 132 lb 3/22/2007 Consumer Brazil
Primary
Concomitant
Petit Mal Epilepsy Other Serious 73 Female 132 lb 4/21/2007 Consumer Brazil
Primary
Concomitant
Raynaud's Phenomenon Hospitalization 1/1/2001 54 Female 7/2/2007 Other Health Professional Canada
Primary
Secondary
Raynaud's Phenomenon Hospitalization 1/1/2001 60 Female 8/30/2007 Physician Canada
Primary
Secondary
Concomitant
Chest Pain Hospitalization 6/15/2007 79 Female 9/5/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 11/9/2004 10/13/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 11/9/2004 11/15/2007 United States
Primary
Secondary
Concomitant
Rib Fracture Other Serious 9/1/2005 80 Female 146 lb 12/18/2007 Physician Australia
Primary
Concomitant
Dry Mouth 9/28/2007 Female 12/28/2007 Physician Japan
Primary
Concomitant
Toothache Other Serious 1/31/2008 51 Female 146 lb 1/31/2008 Consumer United States
Primary
Concomitant
Pain In Extremity Hospitalization 10/1/2007 67 Male 2/8/2008 Consumer United States
Primary
Secondary
Concomitant
Osteonecrosis Required Intervention 2/10/2008 54 Female 175 lb 4/18/2008 Consumer United States
Primary
Secondary
Oral Intake Reduced Other Serious 4/8/2008 78 Female 130 lb 5/24/2008 Consumer United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 10/1/2004 60 Male 175 lb 7/22/2008 Physician
Primary
Concomitant
Upper Limb Fracture Other Serious 5/30/2008 85 Female 7/25/2008 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 11/9/2004 8/20/2008 United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 84 Female 8/28/2008 Physician United Kingdom
Primary
Secondary
Osteonecrosis Disability 5/7/2008 Female 115 lb 8/21/2008 Other Health Professional United States
Primary
Secondary
Oesophagitis Hospitalization 84 Female 9/4/2008 United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 1/1/2003 9/15/2008 United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 84 Female 9/17/2008 Physician United Kingdom
Primary
Secondary
Upper Limb Fracture Other Serious 5/30/2008 85 Female 9/18/2008 Other Health Professional United States
Primary
Secondary
Muscle Spasms Other Serious 6/20/2008 Female 122 lb 9/24/2008 United States
Primary
Secondary
Pharmaceutical Product Complaint Hospitalization 84 Female 9/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Liver Function Test Abnormal Life Threatening 4/18/2008 Female 112 lb 10/1/2008 United States
Primary
Secondary
Oesophagitis Hospitalization 84 Female 9/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Tinnitus Other Serious 5/10/2007 55 Female 125 lb 1/25/2009 Consumer United States
Primary
Secondary
Product Quality Issue 10/1/2008 53 Female 140 lb 1/26/2009 Lawyer United States
Primary
Concomitant
Salivary Hypersecretion 12/27/2008 Female 2/9/2009 Consumer
Primary
Concomitant
Vision Blurred Other Serious 84 Female 119 lb 2/12/2009 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/6/2009 84 Female 119 lb 2/18/2009 Consumer United States
Primary
Concomitant
Salivary Hypersecretion 12/27/2008 Female 2/20/2009 Consumer
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2003 Female 155 lb 2/25/2009 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 6/20/2007 67 Female 138 lb 2/23/2009 Physician United States
Primary
Concomitant
Tooth Loss Required Intervention 73 Female 3/9/2009 United States
Primary
Secondary
Pathological Fracture Hospitalization 2/17/2009 78 Female 3/20/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Rib Fracture Other Serious 9/1/2005 Female 146 lb 4/9/2009 Physician Australia
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 7/9/2001 Female 119 lb 4/17/2009 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/6/2009 84 Female 119 lb 5/19/2009 Consumer United States
Primary
Concomitant
Product Substitution Issue Death 10/31/2008 68 Female 5/14/2009 Pharmacist United States
Primary
Concomitant
Pneumonia Necrotising Hospitalization 6/22/2008 71 Female 117 lb 5/27/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Hip Fracture Other Serious 1/1/2009 59 Female 6/29/2009 Physician Canada
Primary
Secondary
Impaired Healing Other Serious 1/1/2008 71 Male 7/2/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 1/1/2008 71 Male 7/13/2009 Other Health Professional Sweden
Primary
Concomitant
Product Substitution Issue Hospitalization 84 Female 7/31/2009 United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 4/26/2008 85 Female 8/3/2009 Lawyer United States
Primary
Concomitant
Stress Fracture Hospitalization 5/13/2009 Female 128 lb 7/31/2009 Consumer United States
Primary
Secondary
Wrist Fracture Hospitalization 1/31/2007 93 Female 8/5/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 4/26/2008 85 Female 8/10/2009 Lawyer United States
Primary
Concomitant
Sepsis Hospitalization 2/1/2007 84 Female 8/19/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/1/2007 84 Female 8/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Exostosis Hospitalization 1/1/2009 46 Female 8/21/2009 Consumer Germany
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 2/1/2005 64 Female 8/26/2009 Physician United Kingdom
Primary
Secondary
Weight Decreased Hospitalization 4/26/2008 85 Female 8/26/2009 United States
Primary
Concomitant
Oesophageal Injury Disability 6/20/2009 77 Female 150 lb 7/18/2009 Consumer United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 84 Female 9/9/2009 United Kingdom
Primary
Concomitant
Osteonecrosis Other Serious 1/1/2008 71 Male 10/5/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 4/1/2009 67 Female 10/16/2009 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 4/1/2009 67 Female 10/21/2009 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 4/1/2009 67 Female 11/4/2009 Consumer United States
Primary
Secondary
Concomitant
Tension Hospitalization 4/1/2009 67 Female 11/30/2009 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 64 Male 11/24/2009 United States
Primary
Concomitant
Tendon Disorder Other Serious 4/1/2007 60 Female 135 lb 11/20/2009 Consumer United States
Primary
Secondary
Weight Decreased Hospitalization 4/26/2008 85 Female 12/1/2009 United States
Primary
Concomitant
Nausea Disability 5/1/2006 49 Female 11/25/2009 Other Health Professional United States
Primary
Concomitant
Aphonia 12/3/2009 Female 1/13/2010 Consumer
Primary
Concomitant
Osteonecrosis Other Serious 78 Female 1/21/2010 Other Health Professional Sweden
Primary
Secondary
Movement Disorder Hospitalization 1/3/2009 Male 152 lb 1/26/2010 Other Health Professional Canada
Primary
Concomitant
Dysphonia 12/3/2009 Female 1/27/2010 Physician
Primary
Concomitant
Pain In Extremity Other Serious 4/1/2009 67 Female 121 lb 2/3/2010 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 64 Male 1/22/2010 Lawyer United States
Primary
Concomitant
Pneumonia Hospitalization 12/24/2009 Female 2/12/2010 Consumer
Primary
Concomitant
Femur Fracture Required Intervention 3/31/2009 61 Female 229 lb 2/22/2010 United States
Primary
Secondary
Pneumonia Hospitalization 12/24/2009 Female 118 lb 3/3/2010 Physician
Primary
Concomitant
No Therapeutic Response Other Serious Male 246 lb 3/10/2010 Other Health Professional United States
Primary
Concomitant
Spinal Fracture Hospitalization 1/1/2003 60 Female 3/15/2010 Consumer United States
Primary
Secondary
Concomitant
Impaired Healing Hospitalization 12/28/2008 92 Female 135 lb 3/9/2010 Consumer United States
Primary
Secondary
Stress Fracture Required Intervention 9/14/2009 Female 190 lb 3/12/2010 Consumer United States
Primary
Secondary
Spinal Fracture Hospitalization 1/1/2003 60 Female 3/22/2010 Consumer United States
Primary
Secondary
Concomitant
Femur Fracture Hospitalization 8/20/2007 63 Female 145 lb 3/16/2010 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 Female 155 lb 3/23/2010 Physician United States
Primary
Secondary
Concomitant
Femur Fracture Required Intervention 2/10/2010 Female 130 lb 3/19/2010 United States
Primary
Secondary
Eczema Other Serious 12/9/2003 Female 128 lb 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 Female 155 lb 3/26/2010 Physician United States
Primary
Secondary
Concomitant
Femur Fracture Required Intervention 3/4/2010 Female 175 lb 3/25/2010 Consumer United States
Primary
Secondary
Renal Impairment Other Serious 11/6/2006 Male 246 lb 3/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Life Threatening 3/24/2010 3/31/2010 Pharmacist United States
Primary
Concomitant
Tachycardia Hospitalization 1/1/2004 62 Female 163 lb 3/31/2010 Physician United States
Primary
Secondary
Wheezing Hospitalization 69 Female 4/6/2010 Lawyer United States
Primary
Concomitant
Femur Fracture Hospitalization 2/12/2010 89 Female 4/13/2010 Consumer United States
Primary
Secondary
Eczema Other Serious 12/9/2003 67 Female 128 lb 4/7/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 11/6/2006 69 Male 246 lb 4/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Fracture Required Intervention 12/2/2009 63 Female 120 lb 4/8/2010 Consumer United States
Primary
Secondary
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/26/2010 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 1/1/2004 62 Female 163 lb 4/27/2010 Physician United States
Primary
Secondary
Low Turnover Osteopathy Hospitalization 4/1/2003 Female 5/13/2010 Consumer United States
Primary
Secondary
Tooth Disorder Other Serious 1/1/2009 70 Female 152 lb 5/13/2010 Physician United States
Primary
Secondary
Concomitant
Vulvovaginal Dryness Hospitalization 12/1/2009 69 Female 135 lb 5/12/2010 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 1/1/2004 62 Female 163 lb 5/20/2010 Physician United States
Primary
Secondary
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 5/20/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 5/27/2010 United States
Primary
Secondary
Concomitant
Low Turnover Osteopathy Other Serious 5/27/2010 Consumer United States
Primary
Secondary
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/3/2010 United States
Primary
Secondary
Concomitant
Tooth Extraction Hospitalization 1/1/2004 62 Female 163 lb 6/7/2010 Physician United States
Primary
Secondary
Pain In Extremity Other Serious 5/21/2010 62 Female 140 lb 6/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/10/2010 United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2000 57 Female 185 lb 6/11/2010 Physician United States
Primary
Secondary
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/14/2010 United States
Primary
Secondary
Concomitant
Femur Fracture Other Serious 5/1/2008 65 Female 6/15/2010 Lawyer United States
Primary
Secondary
Low Turnover Osteopathy Other Serious 5/1/2008 79 Female 6/15/2010 Consumer United States
Primary
Secondary
Low Turnover Osteopathy Other Serious 5/31/2008 65 Female 6/15/2010 Consumer United States
Primary
Secondary
Low Turnover Osteopathy Other Serious 1/1/2008 79 Female 6/17/2010 Lawyer United States
Primary
Secondary
Ventricular Tachycardia Other Serious 37 Male 6/7/2010 United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 10/1/2002 70 Female 128 lb 6/18/2010 Physician United States
Primary
Secondary
Retinal Tear Other Serious 8/24/2007 Female 6/18/2010 Lawyer United States
Primary
Secondary
Stress Fracture Other Serious 6/5/2008 6/18/2010 Lawyer United States
Primary
Secondary
Treatment Noncompliance Other Serious 1/1/2004 62 Female 163 lb 6/18/2010 Physician United States
Primary
Secondary
Ulcer Other Serious 9/14/2001 64 Female 148 lb 6/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Femur Fracture Other Serious 5/1/2008 65 Female 6/23/2010 Lawyer United States
Primary
Secondary
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/23/2010 United States
Primary
Secondary
Concomitant
Pain Other Serious 5/1/2008 Female 6/24/2010 Lawyer United States
Primary
Secondary
Pain Other Serious 1/1/2008 Female 6/25/2010 Lawyer United States
Primary
Secondary
Tooth Extraction 11/12/2009 70 Female 106 lb 6/12/2010 United States
Primary
Secondary
Transient Ischaemic Attack Hospitalization 1/1/2000 57 Female 185 lb 6/30/2010 Physician United States
Primary
Secondary
Pain In Jaw Disability 67 Female 152 lb 7/1/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 7/7/2010 United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 1/1/2004 62 Female 163 lb 7/12/2010 Physician United States
Primary
Secondary
Ventricular Extrasystoles Other Serious 10/1/2002 70 Female 128 lb 7/13/2010 Physician United States
Primary
Secondary
Wrong Drug Administered Other Serious 1/1/1999 56 Female 179 lb 7/15/2010 Physician United States
Primary
Concomitant
Stress Fracture Disability Female 7/20/2010 Lawyer United States
Primary
Secondary
Transient Ischaemic Attack Hospitalization 1/1/2000 57 Female 185 lb 7/20/2010 Physician United States
Primary
Secondary
Visual Impairment Other Serious 1/1/2001 55 Female 163 lb 7/20/2010 Physician United States
Primary
Secondary
Concomitant
Ulcer Other Serious 9/14/2001 64 Female 148 lb 7/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Other Serious 1/1/2000 57 Female 185 lb 7/22/2010 Physician United States
Primary
Secondary
Wrong Drug Administered Other Serious 1/1/1999 56 Female 179 lb 7/23/2010 Physician United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 10/1/2002 70 Female 128 lb 7/26/2010 Physician United States
Primary
Secondary
Wrong Drug Administered Other Serious 1/1/1999 56 Female 179 lb 8/2/2010 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 8/2/2010 United States
Primary
Secondary
Concomitant
Low Turnover Osteopathy Other Serious 8/5/2010 Consumer United States
Primary
Secondary
Ventricular Extrasystoles Other Serious 9/14/2001 59 Female 148 lb 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data