Alendronate Sodium combined with Famotidine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Po2 Decreased Other Serious 11/24/2005 54 Male 149 lb 1/25/2006 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 4/20/2004 53 Female 95 lb 1/31/2006 Physician Japan
Primary
Concomitant
Pneumonitis Other Serious 11/24/2005 54 Male 149 lb 2/10/2006 Physician Japan
Primary
Concomitant
Nausea Other Serious 11/24/2005 54 Male 149 lb 2/16/2006 Physician Japan
Primary
Concomitant
Nausea Other Serious 11/24/2005 54 Male 149 lb 2/22/2006 Physician Japan
Primary
Concomitant
Ventricular Hypertrophy Other Serious 7/3/2005 Female 195 lb 3/3/2006 Physician United States
Primary
Concomitant
Respiratory Distress Other Serious 4/23/2005 50 Male 126 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Respiratory Disorder Other Serious 4/10/2006 61 Female 114 lb 6/28/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 4/10/2006 61 Female 114 lb 6/28/2006 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 2/1/2003 Female 178 lb 7/26/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/22/2005 65 Female 7/31/2006 Physician Japan
Primary
Secondary
Concomitant
Haemolytic Uraemic Syndrome Other Serious 70 Male 9/1/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Haemolytic Uraemic Syndrome Other Serious 70 Male 9/1/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Pruritus Generalised Hospitalization 8/10/2006 Female 9/21/2006 Pharmacist Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious 3/20/2006 55 Female 12/4/2006 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 3/20/2006 55 Female 2/1/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/9/2007 78 Male 1/30/2007 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 1/9/2007 78 Male 2/28/2007 Physician Japan
Primary
Concomitant
Protein Total Decreased Other Serious 1/9/2007 78 Male 4/9/2007 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 2/3/2007 65 Female 90 lb 7/9/2007 Physician Japan
Primary
Concomitant
Staphylococcal Infection Life Threatening 4/28/2003 Female 15 lb 8/7/2007 Physician Japan
Primary
Concomitant
Vomiting Other Serious 6/22/2006 80 Male 9/12/2007 Physician Japan
Primary
Concomitant
Vomiting Other Serious 6/22/2006 80 Male 10/12/2007 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 11/20/2006 Female 10/18/2007 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/4/2007 64 Male 139 lb 2/1/2008 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 10/19/2007 6 Female 2/6/2008 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 8/21/2007 46 Female 121 lb 3/20/2008 Physician Japan
Primary
Concomitant
Stress Other Serious 10/19/2007 6 Female 4/7/2008 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 3/5/2008 Female 107 lb 5/2/2008 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 3/25/2008 75 Female 5/16/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/30/2007 60 Male 234 lb 5/16/2008 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 3/5/2008 Male 107 lb 6/5/2008 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 3/25/2008 75 Female 6/26/2008 Physician Japan
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Hospitalization 6/7/2008 74 Female 119 lb 7/24/2008 Physician Japan
Primary
Concomitant
Pulmonary Oedema Hospitalization 6/24/2008 73 Female 8/18/2008 Japan
Primary
Concomitant
Haematoma Other Serious 65 Female 8/25/2008
Primary
Concomitant
Pulmonary Embolism Hospitalization Female 123 lb 10/10/2008 Israel
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/27/2008 Female 123 lb 10/16/2008 Israel
Primary
Secondary
Concomitant
Weight Increased Other Serious 29 Female 120 lb 10/18/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Fluctuation Other Serious 29 Female 11/17/2008 Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 Female 60 lb 11/18/2008 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 6/24/2008 73 Female 11/14/2008 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/12/2007 6 Female 11/21/2008 Physician Japan
Primary
Concomitant
Oedema Hospitalization 12/7/2008 83 Female 117 lb 12/26/2008 Consumer Germany
Primary
Concomitant
Pulmonary Oedema Hospitalization 6/24/2008 73 Female 2/17/2009 Physician Japan
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 12/7/2008 83 Female 117 lb 3/13/2009 Other Health Professional Germany
Primary
Concomitant
Urine Output Decreased Hospitalization 12/7/2008 83 Female 117 lb 3/23/2009 Other Health Professional Germany
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 1/23/2009 Female 132 lb 4/6/2009 Japan
Primary
Concomitant
Visual Impairment Other Serious 1/23/2009 Female 132 lb 4/17/2009 Japan
Primary
Concomitant
Visual Impairment Other Serious 1/23/2009 Female 132 lb 4/22/2009 Japan
Primary
Concomitant
Visual Impairment Other Serious 1/23/2009 Female 132 lb 4/22/2009 Japan
Primary
Concomitant
Non-small Cell Lung Cancer Hospitalization 1/21/2009 Male 101 lb 4/24/2009 United States
Primary
Concomitant
Non-small Cell Lung Cancer Hospitalization 1/21/2009 Female 101 lb 4/30/2009 United States
Primary
Concomitant
Visual Impairment Other Serious 1/23/2009 Female 132 lb 5/4/2009 Japan
Primary
Concomitant
Non-small Cell Lung Cancer Hospitalization 1/21/2009 Female 101 lb 5/6/2009 United States
Primary
Concomitant
Foot Deformity Hospitalization 3/10/2009 Female 126 lb 5/19/2009 Japan
Primary
Concomitant
Visual Impairment Other Serious 1/23/2009 Female 132 lb 6/5/2009 Japan
Primary
Concomitant
Foot Deformity Hospitalization 3/10/2009 Female 126 lb 7/8/2009 Japan
Primary
Concomitant
Urinary Tract Infection Life Threatening 2/18/2009 Female 77 lb 8/3/2009 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 6/26/2009 Female 106 lb 8/6/2009 Japan
Primary
Concomitant
Pyrexia Hospitalization 6/26/2009 Female 106 lb 8/13/2009 Japan
Primary
Concomitant
Non-small Cell Lung Cancer Hospitalization 1/21/2009 Female 101 lb 8/17/2009 United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 2/18/2009 Female 77 lb 8/18/2009 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 6/26/2009 Female 106 lb 8/20/2009 Japan
Primary
Concomitant
Non-small Cell Lung Cancer Hospitalization 1/21/2009 Female 104 lb 8/24/2009 United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/14/2009 Female 132 lb 8/26/2009 Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/26/2009 Female 106 lb 8/27/2009 Japan
Primary
Concomitant
Spondylolisthesis Hospitalization 8/27/2009 Female 121 lb 9/10/2009 Japan
Primary
Concomitant
Ventricular Hypokinesia Life Threatening 7/30/2009 48 Male 157 lb 9/18/2009 Physician Japan
Primary
Concomitant
Wheelchair User Hospitalization 6/29/2009 78 Female 9/24/2009 Physician Japan
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 9/8/2009 66 Female 229 lb 10/1/2009 Pharmacist United States
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 7/30/2009 48 Male 157 lb 10/6/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 6/4/2007 64 Male 139 lb 10/13/2009 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 2/18/2009 Female 77 lb 10/22/2009 Physician Japan
Primary
Concomitant
Urinary Tract Infection Life Threatening 2/18/2009 Female 77 lb 10/26/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 6/4/2007 64 Male 139 lb 10/24/2009 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 9/15/2009 Female 128 lb 11/16/2009 Physician Japan
Primary
Secondary
Concomitant
Small Intestine Ulcer Hospitalization 5/15/2009 Female 114 lb 12/2/2009 Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 2/3/2007 65 Female 90 lb 12/17/2009 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 9/29/2009 Female 128 lb 1/5/2010 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 9/29/2009 Female 128 lb 1/13/2010 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 2/1/2009 48 Male 139 lb 1/20/2010 Physician Japan
Primary
Concomitant
Spondylolisthesis Hospitalization 9/1/2009 Female 121 lb 2/5/2010 Japan
Primary
Concomitant
Septic Shock Hospitalization 12/9/2008 Male 2/12/2010 Physician Japan
Primary
Secondary
Concomitant
Synovial Rupture Hospitalization 12/16/2009 Female 2/25/2010 Japan
Primary
Secondary
Concomitant
Spondylolisthesis Hospitalization 9/1/2009 Female 121 lb 3/9/2010 Japan
Primary
Concomitant
Synovial Rupture Hospitalization 12/16/2009 Female 3/2/2010 Japan
Primary
Secondary
Concomitant
Urine Abnormality Other Serious 8/11/2008 Female 123 lb 3/19/2010 Physician Japan
Primary
Secondary
Concomitant
Volvulus Of Small Bowel Hospitalization 10/16/2009 Female 108 lb 3/22/2010 Physician Japan
Primary
Concomitant
Septic Shock Hospitalization 12/9/2008 Male 132 lb 3/23/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 6/30/2007 70 Male 3/16/2010 Other Health Professional Japan
Primary
Concomitant
Tachycardia Other Serious 2/2/2010 27 Male 119 lb 3/30/2010 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 2/24/2010 69 Male 86 lb 4/5/2010 Physician Japan
Primary
Concomitant
Retroperitoneal Abscess Hospitalization 10/10/2009 78 Female 4/8/2010 Physician Japan
Primary
Concomitant
Shock Hospitalization 2/24/2010 74 Female 97 lb 4/9/2010 Physician Japan
Primary
Concomitant
Herpes Zoster Hospitalization 10/24/2008 78 Female 123 lb 4/13/2010 Physician Japan
Primary
Secondary
Concomitant
Asthma Hospitalization 8/23/2009 75 Female 130 lb 4/26/2010 Physician Japan
Primary
Concomitant
Cardiac Failure Hospitalization 2/1/2010 67 Female 90 lb 5/24/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 6/26/2009 49 Female 106 lb 6/18/2010 Physician Japan
Primary
Concomitant
Cardiac Failure Hospitalization 2/1/2010 67 Female 90 lb 6/30/2010 Physician Japan
Primary
Concomitant
Cerebellar Infarction Hospitalization 3/2/2010 66 Male 7/12/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 6/26/2009 49 Female 106 lb 7/19/2010 Physician Japan
Primary
Concomitant
Hypersensitivity Hospitalization 2/1/2010 67 Female 150 lb 5/18/2010 United States
Primary
Concomitant
Tendon Rupture Hospitalization 3/25/2009 66 Female 127 lb 8/3/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebellar Infarction Hospitalization 3/2/2010 66 Male 8/16/2010 Physician Japan
Primary
Concomitant
Tendon Rupture Hospitalization 3/25/2009 66 Female 127 lb 8/16/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/26/2009 49 Female 106 lb 8/17/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 6/26/2009 49 Female 106 lb 8/30/2010 Physician Japan
Primary
Concomitant
Tendon Rupture Hospitalization 3/25/2009 66 Female 127 lb 9/2/2010 Physician Japan
Primary
Secondary
Concomitant
Tendon Rupture Hospitalization 3/25/2009 66 Female 127 lb 9/10/2010 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Other Serious 6/17/2010 67 Female 9/14/2010 Other Health Professional Japan
Primary
Concomitant
Pain Life Threatening 5/9/2010 79 Male 205 lb 9/22/2010 Physician Germany
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 6/17/2010 67 Female 10/4/2010 Other Health Professional Japan
Primary
Concomitant
Encephalitis Hospitalization 9/20/2010 11/17/2010 Physician Japan
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2010 69 Female 12/6/2010 Physician Japan
Primary
Secondary
Myocardial Infarction Life Threatening 1/1/2010 69 Female 12/13/2010 Physician Japan
Primary
Concomitant
Diffuse Large B-cell Lymphoma Stage Iii Hospitalization 6/17/2010 67 Female 11/23/2010 Other Health Professional Japan
Primary
Concomitant
Nausea 10/6/2009 12/14/2010 Consumer United States
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 9/2/2010 67 Female 12/1/2010 Other Health Professional Japan
Primary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 9/2/2010 67 Female 12/16/2010 Other Health Professional Japan
Primary
Concomitant
Subcutaneous Abscess Hospitalization 12/16/2009 56 Female 12/15/2010 Japan
Primary
Secondary
Concomitant
Deafness Bilateral Other Serious 2/1/2010 68 Female 132 lb 1/12/2011 Physician Japan
Primary
Concomitant
Encephalitis Hospitalization 9/20/2010 1/21/2011 Physician Japan
Primary
Secondary
Concomitant
Haematocrit Decreased Hospitalization 1/1/2011 58 Female 1/13/2011 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2011 58 Female 1/18/2011 Other Health Professional Japan
Primary
Concomitant
Pain In Extremity Hospitalization 1/1/2011 58 Female 1/24/2011 Other Health Professional Japan
Primary
Concomitant
Red Blood Cell Count Decreased Life Threatening 1/1/2011 58 Female 2/8/2011 Other Health Professional Japan
Primary
Concomitant
Conjunctival Hyperaemia Life Threatening 1/1/2010 69 Female 3/15/2011 Physician Japan
Primary
Concomitant
Gamma-glutamyltransferase Increased Disability 1/1/2011 58 Female 3/4/2011 Other Health Professional Japan
Primary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 1/1/2011 58 Female 3/10/2011 Other Health Professional Japan
Primary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 9/2/2010 67 Female 3/14/2011 Other Health Professional Japan
Primary
Concomitant
Immunosuppression Hospitalization 8/20/2010 72 Female 119 lb 3/30/2011 Physician Japan
Primary
Secondary
Concomitant
Dyspnoea Required Intervention 3/30/2011 80 Female 3/30/2011 Pharmacist United States
Primary
Concomitant
Hepatic Enzyme Increased Death 6/4/2007 64 Male 139 lb 3/30/2011 Physician Japan
Primary
Secondary
Concomitant
Multiple Myeloma Death 4/3/2010 74 Female 4/12/2011 Pharmacist United States
Primary
Concomitant
Diffuse Large B-cell Lymphoma Stage Iii Other Serious 9/2/2010 67 Female 4/11/2011 Physician Japan
Primary
Concomitant
Interleukin-2 Receptor Increased Hospitalization 12/24/2010 76 Male 5/4/2011 Physician Japan
Primary
Concomitant
Radiation Pneumonitis Hospitalization 4/6/2011 60 Male 126 lb 5/18/2011 Consumer Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/27/2009 74 Female 94 lb 5/23/2011 Physician Japan
Primary
Secondary
Concomitant
Dizziness Other Serious 9/27/2009 74 Female 94 lb 5/24/2011 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Factor Increased Hospitalization 9/27/2009 74 Female 94 lb 6/8/2011 Physician Japan
Primary
Secondary
Concomitant
Deafness Bilateral Other Serious 2/1/2010 68 Female 132 lb 6/10/2011 Physician Japan
Primary
Concomitant
Non-hodgkin's Lymphoma Stage Iii Hospitalization 9/2/2010 67 Female 6/29/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Infection Other Serious 8/20/2010 72 Female 119 lb 7/8/2011 Physician Japan
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Stage Iii Hospitalization 9/2/2010 67 Female 7/14/2011 Physician Japan
Primary
Concomitant
Hyperamylasaemia Hospitalization 12/6/2008 32 Female 90 lb 7/21/2011 Physician Japan
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 5/9/2011 45 Female 117 lb 7/25/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 4/28/2011 84 Female 7/26/2011 Physician Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 11/1/2010 79 Male 88 lb 7/27/2011 Physician Japan
Primary
Concomitant
Interacting
Toxicity To Various Agents Death 7/15/2011 96 Male 163 lb 7/28/2011 Pharmacist United States
Primary
Concomitant

Drug Data