Alendronate Sodium combined with Digoxin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence Hospitalization 9/4/2005 89 Male 170 lb 1/10/2006 United States
Primary
Concomitant
Pruritus Death 7/22/2004 Male 187 lb 1/25/2006 United Kingdom
Primary
Concomitant
Cerebrovascular Accident Death 4/1/2005 Female 125 lb 2/2/2006 United States
Primary
Concomitant
Hyperglycaemia Hospitalization 1/25/2006 78 Female 196 lb 2/3/2006 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Hypertrophy Other Serious 7/3/2005 Female 195 lb 3/3/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2005 Female 129 lb 3/9/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 10/1/2004 94 Female 103 lb 12/27/2005 Consumer United States
Primary
Concomitant
Tinnitus Hospitalization 8/1/2001 78 Female 3/31/2006 Lawyer Poland
Primary
Concomitant
Tinnitus Hospitalization 8/1/2001 78 Female 4/7/2006 Physician Poland
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Required Intervention 12/1/2005 77 Female 12/2/2005 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 70 Female 5/22/2006 Other Health Professional Canada
Primary
Concomitant
Interacting
Tearfulness Hospitalization 3/8/2006 Female 6/30/2006 Other Health Professional France
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 3/14/2006 Female 148 lb 3/21/2006 Pharmacist United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2006 Female 11/3/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 Female 11/9/2006 Consumer Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/5/2006 91 Female 11/3/2006 Sweden
Primary
Secondary
Concomitant
Cardiac Murmur Hospitalization 4/24/2006 Female 160 lb 11/16/2006 Consumer Canada
Primary
Concomitant
Cardiomegaly Other Serious 4/24/2006 Female 160 lb 12/14/2006 Consumer Canada
Primary
Concomitant
Convulsion Hospitalization 10/15/2006 Male 141 lb 1/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/1/2006 Female 128 lb 8/17/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 8/1/2006 Female 128 lb 8/17/2006 Pharmacist United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 10/6/2006 77 Male 123 lb 12/12/2006 Pharmacist United States
Primary
Secondary
Concomitant
Drug Level Increased Hospitalization 12/3/2006 Male 138 lb 2/23/2007 Pharmacist Japan
Primary
Concomitant
Interacting
Thrombocytopenia Hospitalization 78 Male 4/30/2007 Other Health Professional United States
Primary
Concomitant
Surgery Hospitalization 4/1/2007 Female 190 lb 6/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Soft Tissue Infection Other Serious 1/17/2007 Male 271 lb 7/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 12/17/2006 Female 8/8/2007 Physician United States
Primary
Concomitant
Tibia Fracture Hospitalization 4/1/2006 76 Female 8/14/2007 Germany
Primary
Concomitant
Pneumonia Bacterial Hospitalization 12/17/2006 Female 8/15/2007 Physician United States
Primary
Concomitant
B-cell Lymphoma Death 1/15/2007 Male 185 lb 9/19/2007 United Kingdom
Primary
Secondary
Concomitant
Surgery Hospitalization 4/1/2007 Female 190 lb 12/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 8/6/2007 Male 145 lb 12/14/2007 Physician United States
Primary
Concomitant
Anaemia Other Serious 70 Male 12/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaemia Other Serious 70 Male 12/21/2007 United Kingdom
Primary
Secondary
Concomitant
Anaemia Other Serious 70 Male 12/21/2007 United Kingdom
Primary
Secondary
Concomitant
Malaise Hospitalization 7/2/2007 Male 1/21/2008 United Kingdom
Primary
Concomitant
Respiratory Tract Infection Viral Other Serious 12/15/2007 75 Female 129 lb 2/1/2008 Greece
Primary
Concomitant
Tibia Fracture Hospitalization 4/1/2006 76 Female 2/8/2008 Germany
Primary
Secondary
Concomitant
Metastatic Gastric Cancer Death 1/15/2007 Male 185 lb 2/22/2008 United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 11/1/2007 Female 160 lb 2/22/2008 Canada
Primary
Concomitant
Respiratory Tract Infection Viral Other Serious 12/15/2007 75 Female 129 lb 2/22/2008 Greece
Primary
Concomitant
Torsade De Pointes Hospitalization 2/8/2008 79 Female 3/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Streptococcal Sepsis Other Serious 4/1/2007 Female 190 lb 3/7/2008 United Kingdom
Primary
Secondary
Concomitant
Respiratory Tract Infection Viral Other Serious 12/15/2007 75 Female 129 lb 4/10/2008 Greece
Primary
Concomitant
Skin Exfoliation Hospitalization 3/1/2008 84 Female 5/5/2008 Physician Brazil
Primary
Concomitant
Pleural Effusion Hospitalization 5/1/2008 Female 5/20/2008 Physician Japan
Primary
Concomitant
Malaise Hospitalization 7/2/2007 Male 5/30/2008 United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 5/1/2008 Female 6/3/2008 Physician Japan
Primary
Concomitant
Pain In Extremity Other Serious 6/1/2008 Female 160 lb 6/27/2008 Canada
Primary
Concomitant
Carcinoma In Situ Of Skin Other Serious 4/4/2007 Female 137 lb 7/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hypertension Death 3/23/2008 Female 139 lb 8/15/2008 United Kingdom
Primary
Concomitant
Hypertension Death 3/23/2008 Female 139 lb 8/15/2008 United Kingdom
Primary
Concomitant
Sinus Bradycardia Hospitalization 5/15/2008 73 Female 8/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 83 Female 9/12/2008 United States
Primary
Concomitant
Oesophageal Ulcer Hospitalization 5/15/2008 73 Female 119 lb 9/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 5/18/2008 108 lb 9/30/2008 Japan
Primary
Concomitant
Serotonin Syndrome Other Serious 8/28/2008 Female 10/1/2008 Physician Japan
Primary
Secondary
Concomitant
Sarcoidosis Other Serious 2/1/2008 Female 130 lb 10/3/2008 United Kingdom
Primary
Concomitant
Heart Rate Irregular Other Serious 81 Female 132 lb 10/1/2008 United States
Primary
Concomitant
Cardiac Failure Death 5/18/2008 Female 108 lb 10/10/2008 Japan
Primary
Concomitant
Serotonin Syndrome Hospitalization 8/29/2008 Female 10/10/2008 Physician Japan
Primary
Secondary
Concomitant
Interacting
Metastatic Gastric Cancer Death 1/15/2007 Male 185 lb 11/19/2008 United Kingdom
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Death 1/15/2007 72 Male 185 lb 11/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 6/1/2008 Female 160 lb 11/20/2008 Canada
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 10/21/2008 86 Female 11/28/2008 United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/29/2008 Male 1/13/2009 United Kingdom
Primary
Concomitant
Infection Hospitalization 8/19/2007 Male 1/13/2009 United Kingdom
Primary
Concomitant
Infective Exacerbation Of Chronic Obstructive Airways Disease Hospitalization 8/19/2007 Male 1/14/2009 United Kingdom
Primary
Concomitant
Sarcoidosis Other Serious 2/1/2008 Female 130 lb 1/19/2009 United Kingdom
Primary
Concomitant
Atrial Fibrillation Required Intervention 5/7/2008 85 Male 175 lb 5/8/2008 Pharmacist United States
Primary
Concomitant
Vision Blurred Hospitalization 6/20/2007 67 Female 138 lb 2/23/2009 Physician United States
Primary
Concomitant
Pleural Effusion Other Serious 3/25/2009 65 Female 190 lb 4/3/2009 Pharmacist United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/14/2009 75 5/18/2009 United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/14/2009 75 143 lb 6/1/2009 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/14/2009 75 5/27/2009 Consumer United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/14/2009 75 6/8/2009 United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 1/9/2009 Female 148 lb 6/22/2009 Physician United Kingdom
Primary
Concomitant
Osteonecrosis Hospitalization 72 Male 6/30/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/9/2009 80 Female 7/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/26/2008 85 Female 8/3/2009 Lawyer United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/31/2007 93 Female 8/5/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 4/26/2008 85 Female 8/10/2009 Lawyer United States
Primary
Concomitant
Sepsis Hospitalization 2/1/2007 84 Female 8/19/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/1/2007 84 Female 8/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Wrist Fracture Hospitalization 1/31/2007 93 Female 8/13/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 8/18/2009 Lawyer United States
Primary
Concomitant
Diabetes Mellitus Death 8/6/2009 84 Male 9/1/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 4/26/2008 85 Female 8/26/2009 United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/31/2007 93 Female 8/31/2009 United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/31/2007 93 Female 9/4/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 79 Female 9/8/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Death 8/6/2009 84 Male 9/14/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 79 Female 9/8/2009 United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/31/2007 93 Female 9/8/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 9/21/2009 United States
Primary
Concomitant
Pneumonia Hospitalization 4/8/2009 90 Female 88 lb 8/31/2009 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Other Serious Male 10/19/2009 United States
Primary
Concomitant
Pulmonary Hypertension Death 9/23/2009 Female 10/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 79 Female 11/18/2009 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 11/16/2009 Lawyer United States
Primary
Concomitant
Venous Insufficiency Hospitalization 69 Female 11/18/2009 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 11/24/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 64 Male 11/24/2009 United States
Primary
Concomitant
Pulmonary Hypertension Death 9/23/2009 Female 12/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 4/26/2008 85 Female 12/1/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 11/27/2009 Female 170 lb 12/17/2009 Consumer United States
Primary
Secondary
Concomitant
Neutropenia Life Threatening 12/14/2009 Male 184 lb 1/20/2010 United States
Primary
Secondary
Concomitant
Death Death Female 150 lb 2/1/2010 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 64 Male 1/22/2010 Lawyer United States
Primary
Concomitant
Neutropenia Other Serious 12/14/2009 Male 184 lb 2/9/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2010 Female 132 lb 2/12/2010 Physician United Kingdom
Primary
Concomitant
Myasthenia Gravis Hospitalization 4/16/2009 Female 257 lb 2/16/2010 Physician South Africa
Primary
Secondary
Concomitant
Sudden Death Death 2/2/2010 81 Female 2/23/2010 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 12/1/2009 70 Female 100 lb 2/6/2010 Consumer United States
Primary
Concomitant
Urine Output Decreased Hospitalization 6/2/2009 Male 3/15/2010 United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 3/31/2010 United States
Primary
Concomitant
Wheezing Hospitalization 69 Female 4/6/2010 Lawyer United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 3/2/2010 82 Male 140 lb 3/23/2010 Physician United States
Primary
Concomitant
Septic Shock Death 4/1/2007 65 Female 4/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization Male 5/4/2010 United States
Primary
Concomitant
Septic Shock Life Threatening 4/4/2010 82 Female 5/7/2010 Physician United States
Primary
Concomitant
Cardiac Failure Hospitalization 2/1/2010 67 Female 90 lb 5/24/2010 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 6/7/2010 United States
Primary
Concomitant
Pain In Extremity Disability 10/13/2007 44 Female 125 lb 6/18/2010 Other Health Professional United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 3/2/2010 82 Male 140 lb 6/23/2010 Physician United States
Primary
Concomitant
Cardiac Failure Hospitalization 2/1/2010 67 Female 90 lb 6/30/2010 Physician Japan
Primary
Concomitant
Tachycardia Hospitalization 6/22/2010 71 Female 7/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mixed Liver Injury Hospitalization 6/28/2010 78 Female 7/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Myalgia 1/1/2009 80 Female 109 lb 7/31/2010 Consumer United States
Primary
Concomitant
Interacting
Klebsiella Test Positive Hospitalization 7/7/2010 82 Female 7/31/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/11/2010 64 Male 8/6/2010 United States
Primary
Concomitant
Insomnia Hospitalization 8/5/2008 80 Female 86 lb 8/23/2010 Physician Japan
Primary
Concomitant
International Normalised Ratio Decreased 2/1/2010 78 Female 160 lb 8/28/2010 United States
Primary
Concomitant
Wrist Fracture Other Serious 93 Female 9/9/2010 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Death 12/18/2008 79 Male 10/11/2010 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/15/2010 74 Male 11/16/2010 Pharmacist Ireland
Primary
Concomitant
Insomnia Hospitalization 8/5/2008 80 Female 86 lb 12/22/2010 Physician Japan
Primary
Concomitant
Pain In Extremity 7/15/2010 12/23/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/15/2010 74 Male 1/20/2011 Pharmacist Ireland
Primary
Concomitant
Stress Urinary Incontinence Hospitalization 4/26/2008 85 Female 100 lb 1/13/2011 Lawyer United States
Primary
Concomitant
Insomnia Other Serious 8/5/2008 80 Female 86 lb 3/15/2011 Physician Japan
Primary
Concomitant
Odynophagia 2/18/2011 82 Female 3/16/2011 Consumer United States
Primary
Concomitant
Hyperglycaemia Hospitalization 8/5/2008 80 Female 86 lb 4/8/2011 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 6/28/2010 75 Female 90 lb 4/12/2011 Other Health Professional United Kingdom
Primary
Concomitant
Muscular Weakness Hospitalization 77 Female 124 lb 4/29/2011 Consumer United States
Primary
Concomitant
Blood Creatinine Increased Other Serious 4/20/2011 75 Female 6/1/2011 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data