Alendronate Sodium combined with Clonazepam

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Trismus Other Serious 1/5/2006 Male 176 lb 2/2/2006 Pharmacist United States
Primary
Concomitant
Rash Life Threatening 11/13/2005 45 Female 140 lb 2/7/2006 United States
Primary
Concomitant
Psychotic Disorder Other Serious 2/2/2006 56 Female 167 lb 4/12/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 3/5/2003 52 Female 5/1/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Rash Required Intervention 11/13/2005 45 Female 140 lb 5/2/2006 United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 3/5/2003 52 Female 5/11/2006 Canada
Primary
Secondary
Concomitant
Ventricular Extrasystoles Life Threatening 8/4/2005 56 Female 243 lb 6/14/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 1/1/2006 68 Female 9/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Infection Hospitalization 8/17/2006 Female 148 lb 9/25/2006 Physician Czech Republic
Primary
Concomitant
Tendon Rupture Hospitalization 3/1/2006 Female 210 lb 10/6/2006 Consumer United States
Primary
Concomitant
Portal Vein Thrombosis Death 6/10/2006 66 Female 126 lb 10/18/2006 Physician Japan
Primary
Concomitant
Speech Disorder Other Serious 6/1/2006 Female 148 lb 11/17/2006 Physician Czech Republic
Primary
Concomitant
Hypoglycaemia Hospitalization 12/16/2006 58 Male 2/15/2007 Pharmacist United States
Primary
Secondary
Concomitant
Speech Disorder Other Serious 6/1/2006 Female 139 lb 2/23/2007 Physician Czech Republic
Primary
Concomitant
Thrombocytopenia Other Serious 6/1/2006 Female 139 lb 2/26/2007 Physician Czech Republic
Primary
Concomitant
Basal Cell Carcinoma Required Intervention 1/26/2006 56 Female 117 lb 2/22/2007 Other Health Professional United States
Primary
Concomitant
Basal Cell Carcinoma Required Intervention 12/2/2005 56 Female 117 lb 3/9/2007 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 12/19/2006 Female 141 lb 4/5/2007 Belgium
Primary
Concomitant
Thrombocytopenia Hospitalization 12/19/2006 Female 141 lb 4/18/2007 Belgium
Primary
Concomitant
Delirium Hospitalization 7/28/2007 62 Male 141 lb 9/27/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Death 9/29/2007 63 Male 10/18/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/28/2007 62 Male 141 lb 11/2/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/28/2007 62 Male 141 lb 11/9/2007 Physician Japan
Primary
Secondary
Concomitant
Road Traffic Accident Other Serious 57 Male 11/28/2007
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 80 Female 11/29/2007 Finland
Primary
Concomitant
Transaminases Increased Other Serious 80 Female 11/30/2007
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/28/2007 62 Male 141 lb 11/26/2007 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Hypertension Death Female 187 lb 12/4/2007 United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/10/2004 52 Female 134 lb 1/16/2008 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 7/28/2007 62 Male 141 lb 3/5/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombosis Other Serious 1/22/2008 Female 151 lb 5/2/2008 Brazil
Primary
Concomitant
Joint Contracture 3/13/2008 Female 186 lb 6/12/2008 Consumer United States
Primary
Concomitant
Somnolence Other Serious 7/10/2008 60 Male 7/21/2008 Physician Guatemala
Primary
Concomitant
Drug Level Decreased Other Serious 6/29/2008 64 Male 8/15/2008 Other Health Professional France
Primary
Concomitant
Interacting
Pruritus 5/1/2008 Female 222 lb 8/29/2008 Consumer United States
Primary
Concomitant
Pain Other Serious 10/2/2008 Female 10/15/2008 Pharmacist Canada
Primary
Concomitant
Myalgia Other Serious 10/19/2008 Female 109 lb 11/11/2008 Lawyer United States
Primary
Concomitant
Cerebrovascular Accident Death 1/1/2007 58 Female 11/7/2008 Physician United States
Primary
Concomitant
Cerebrovascular Accident Death 1/1/2007 58 Female 11/24/2008 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection 6/10/2008 Female 180 lb 12/12/2008 Physician United States
Primary
Secondary
Concomitant
Cyanosis Other Serious 7/19/2008 55 Female 129 lb 12/8/2008 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 12/19/2006 Female 141 lb 12/18/2008 Belgium
Primary
Concomitant
Vomiting Hospitalization 10/1/2008 Female 12/26/2008 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 114 lb 12/26/2008 Pharmacist United States
Primary
Concomitant
Arterial Occlusive Disease Hospitalization 2/3/2009 Female 170 lb 2/20/2009 Other Health Professional Canada
Primary
Concomitant
Spinal Disorder Hospitalization 12/1/2007 87 Male 2/26/2009 Consumer Mexico
Primary
Concomitant
Vasculitis Hospitalization 2/1/2009 Female 170 lb 3/2/2009 Other Health Professional Canada
Primary
Concomitant
Anaemia Other Serious 66 Female 132 lb 7/31/2009 Physician United Kingdom
Primary
Concomitant
Visual Impairment Other Serious 1/21/2008 Female 137 lb 8/24/2009 Brazil
Primary
Concomitant
Haemoglobin Decreased Other Serious 4/8/2009 66 Female 132 lb 9/2/2009 Physician United Kingdom
Primary
Concomitant
Anaemia Other Serious 66 Female 132 lb 9/2/2009 Physician United Kingdom
Primary
Concomitant
Anaemia Other Serious 66 Female 132 lb 9/2/2009 Physician United Kingdom
Primary
Concomitant
Joint Contracture 3/13/2008 Female 186 lb 9/12/2009 Consumer United States
Primary
Concomitant
Vasculitis Hospitalization 2/1/2009 Female 170 lb 9/18/2009 Other Health Professional Canada
Primary
Concomitant
Vasculitis Hospitalization 9/21/2009 46 Female 161 lb 10/1/2009 Pharmacist United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/10/2009 Female 132 lb 10/19/2009 Physician Japan
Primary
Concomitant
Hypersomnia Other Serious 54 Female 11/20/2009 Canada
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/10/2009 Female 132 lb 12/23/2009 Physician Japan
Primary
Concomitant
Intestinal Adenocarcinoma Other Serious 11/26/2009 59 Female 178 lb 1/21/2010 Physician Canada
Primary
Secondary
Concomitant
Intestinal Adenocarcinoma Other Serious 11/26/2009 59 Female 178 lb 1/25/2010 Physician Canada
Primary
Secondary
Concomitant
Sputum Discoloured Other Serious 1/1/2008 Female 180 lb 2/26/2010 United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/10/2009 Female 132 lb 3/4/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Death 2/20/2010 50 Male 157 lb 4/5/2010 Physician Japan
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/21/2008 63 Female 137 lb 7/2/2010 Other Health Professional Brazil
Primary
Concomitant
Wound Infection Other Serious 11/26/2009 59 Female 178 lb 7/6/2010 Physician Canada
Primary
Secondary
Concomitant
Wound Infection Other Serious 11/26/2009 59 Female 178 lb 7/8/2010 Physician Canada
Primary
Secondary
Concomitant
Vomiting Other Serious 52 Male 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vascular Graft Hospitalization 8/23/2010 71 Female 173 lb 10/11/2010 Other Health Professional Canada
Primary
Concomitant
Vascular Graft Hospitalization 10/1/2010 71 Female 173 lb 11/4/2010 Other Health Professional Canada
Primary
Concomitant
Wound Infection Other Serious 1/1/2010 73 Female 126 lb 12/17/2010 Physician Brazil
Primary
Secondary
Concomitant
Wound Infection Other Serious 1/1/2010 73 Female 126 lb 12/27/2010 Physician Brazil
Primary
Secondary
Concomitant
Femoral Artery Occlusion Hospitalization 8/23/2010 71 Female 173 lb 1/28/2011 Other Health Professional Canada
Primary
Concomitant
Bronchitis 12/1/2009 82 Female 102 lb 1/28/2011 Physician United States
Primary
Concomitant
Fall Other Serious 1/1/2010 73 Female 126 lb 2/9/2011 Consumer Brazil
Primary
Secondary
Concomitant
Thrombosis Other Serious 1/1/2010 73 Female 126 lb 2/11/2011 Consumer Brazil
Primary
Secondary
Concomitant
Gastrointestinal Pain Hospitalization 6/11/2010 53 Female 132 lb 3/4/2011 Consumer Brazil
Primary
Concomitant
Ill-defined Disorder Other Serious 6/11/2010 53 Female 132 lb 3/8/2011 Consumer Brazil
Primary
Concomitant
Endophthalmitis Hospitalization 4/10/2011 75 Female 5/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious Female 124 lb 5/11/2011 Physician United States
Primary
Concomitant
Nephrogenic Anaemia Hospitalization 4/14/2009 72 Male 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Arrhythmia Other Serious 12/1/2010 47 Female 231 lb 7/5/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Malaise Disability 83 Female 165 lb 7/16/2011 Pharmacist Canada
Primary
Concomitant
Convulsion Other Serious 7/10/2011 51 Female 135 lb 7/22/2011 Consumer Canada
Primary
Concomitant
Pain Other Serious 5/28/2010 66 Female 148 lb 8/2/2011 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 5/17/2010 50 Male 159 lb 8/12/2011 Physician France
Primary
Secondary
Concomitant
Fall Hospitalization 12/9/2010 90 Female 143 lb 8/15/2011 Physician Japan
Primary
Concomitant
Impaired Gastric Emptying Disability Female 185 lb 8/18/2011 Consumer United States
Primary
Secondary
Concomitant
Arrhythmia Other Serious 12/1/2010 47 Female 231 lb 8/25/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 6/11/2010 53 Female 132 lb 8/31/2011 Consumer Brazil
Primary
Concomitant
Pulmonary Embolism Hospitalization 5/17/2010 50 Male 159 lb 9/12/2011 Physician France
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 1/1/2003 72 Female 9/16/2011 Venezuela
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/10/2009 71 Female 132 lb 10/3/2011 Physician Japan
Primary
Concomitant
Pulmonary Embolism Hospitalization 5/17/2010 50 Male 159 lb 10/6/2011 Physician France
Primary
Secondary
Concomitant
Hallucination Other Serious 9/1/2011 61 Female 132 lb 10/20/2011 United States
Primary
Secondary
Contusion Other Serious 10/3/2011 88 Female 10/21/2011 Physician Japan
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 10/31/2007 35 Female 116 lb 10/19/2011 Consumer United States
Primary
Concomitant
Drug Ineffective Hospitalization 1/1/2007 49 Female 185 lb 10/28/2011 Physician United States
Primary
Secondary
Concomitant
Joint Swelling Other Serious 1/1/2007 49 Female 185 lb 11/1/2011 United States
Primary
Secondary
Concomitant
Somnolence Other Serious 10/3/2011 88 Female 11/2/2011 Physician Japan
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 1/1/2007 49 Female 185 lb 11/2/2011 United States
Primary
Secondary
Concomitant
Neoplasm Progression Other Serious 7/10/2011 51 Female 135 lb 11/3/2011 Physician Canada
Primary
Concomitant
Disease Progression Other Serious 7/9/2011 51 Female 135 lb 11/7/2011 Physician Canada
Primary
Concomitant
Back Disorder Hospitalization 1/1/2004 68 Female 11/16/2011 Consumer United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 1/1/2004 68 Female 11/22/2011 Consumer United States
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 9/12/2011 82 Female 112 lb 12/20/2011 Pharmacist United States
Primary
Concomitant
Immune System Disorder Hospitalization 1/1/2007 49 Female 185 lb 12/21/2011 United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 5/17/2010 50 Male 159 lb 1/25/2012 Physician France
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 10/30/2011 84 Female 1/27/2012 Other Health Professional France
Primary
Secondary
Concomitant
Fall Hospitalization 1/1/2004 68 Female 1/27/2012 Consumer United States
Primary
Secondary
Concomitant
Immunodeficiency Other Serious 1/21/2008 63 Female 137 lb 2/3/2012 Other Health Professional Brazil
Primary
Concomitant
Fall Disability 10/3/2011 88 Female 2/9/2012 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2008 56 Female 137 lb 2/13/2012 Consumer Brazil
Primary
Concomitant
Deafness Other Serious 5/1/2010 59 Female 161 lb 2/15/2012 Consumer Brazil
Primary
Concomitant
Wheezing Other Serious 7/1/2011 48 Male 160 lb 2/27/2012 Consumer United States
Primary
Concomitant
Cough Other Serious 7/1/2011 48 Male 160 lb 3/2/2012 Consumer United States
Primary
Concomitant
Aspiration Disability 1/3/2012 57 Female 3/15/2012 Other Health Professional United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/10/2009 71 Female 132 lb 3/22/2012 Physician Japan
Primary
Concomitant
Blood Pressure Decreased Other Serious 11/5/2010 56 Male 3/28/2012 Physician Japan
Primary
Concomitant
Impaired Work Ability Other Serious 2/20/2012 61 Female 142 lb 3/22/2012 Consumer United States
Primary
Concomitant
Impaired Work Ability Other Serious 2/20/2012 61 Female 142 lb 4/2/2012 Consumer United States
Primary
Concomitant
Body Height Decreased Other Serious 1/1/2008 56 Female 137 lb 4/10/2012 Consumer Brazil
Primary
Concomitant
Fatty Liver Alcoholic Other Serious 6/1/2006 43 Male 4/11/2012 Other Health Professional France
Primary
Secondary
Concomitant
Nausea 4/12/2012 Other Health Professional United States
Primary
Concomitant
Hepatic Cirrhosis Other Serious 6/1/2006 43 Male 4/13/2012 Physician France
Primary
Secondary
Concomitant
Hyperhidrosis Hospitalization 59 Female 5/6/2012 Consumer Brazil
Primary
Secondary
Concomitant
Fungal Infection Hospitalization Female 152 lb 5/21/2012 Lawyer United States
Primary
Concomitant
Tooth Fracture Disability 1/1/2002 61 Female 5/25/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Osteoarthritis Other Serious 1/1/2010 59 Female 183 lb 5/28/2012 United States
Primary
Concomitant
Bundle Branch Block Left Other Serious 1/1/2002 61 Female 5/31/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 68 Female 5/23/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 68 Female 5/25/2012 United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 12/25/2011 73 Female 156 lb 6/4/2012 Consumer United States
Primary
Concomitant
Foot Fracture Other Serious 1/1/2010 59 Female 183 lb 6/8/2012 United States
Primary
Concomitant
Pneumonia Aspiration Other Serious 12/25/2011 73 Female 156 lb 6/8/2012 Consumer United States
Primary
Concomitant
Blood Pressure Decreased Hospitalization 68 Female 185 lb 5/31/2012 Physician United States
Primary
Secondary
Concomitant
Apnoea Other Serious 68 Female 185 lb 6/4/2012 Physician United States
Primary
Secondary
Concomitant
Death Death 4/23/2012 66 Female 6/13/2012 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 4/23/2012 66 Female 6/18/2012 Physician United Kingdom
Primary
Concomitant
Osteoarthritis Other Serious 1/1/2010 59 Female 183 lb 6/19/2012 Lawyer United States
Primary
Concomitant
Mobility Decreased Hospitalization Female 176 lb 6/25/2012 Consumer Brazil
Primary
Concomitant
Death Death 4/23/2012 66 Female 6/25/2012 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 4/23/2012 66 Female 6/29/2012 Physician United Kingdom
Primary
Concomitant
Serotonin Syndrome Other Serious 68 Female 185 lb 7/12/2012 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 82 Female 121 lb 6/29/2012 Consumer Brazil
Primary
Secondary
Concomitant
Convulsion Other Serious 10/1/2010 75 Female 119 lb 7/20/2012 Consumer Brazil
Primary
Concomitant
Apparent Death Other Serious 12/25/2011 73 Female 156 lb 7/24/2012 Consumer United States
Primary
Concomitant
Rib Fracture 1/1/2011 67 Female 7/26/2012 Consumer United States
Primary
Concomitant
Serotonin Syndrome Other Serious 68 Female 185 lb 8/7/2012 Physician United States
Primary
Secondary
Cerebrovascular Accident Other Serious 1/1/2010 59 Female 183 lb 8/9/2012 Consumer United States
Primary
Concomitant
Injection Site Haematoma Other Serious 3/1/2011 74 Female 150 lb 8/13/2012 Physician United States
Primary
Concomitant

Drug Data