Alendronate Sodium combined with Azathioprine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Serotonin Syndrome 75 Female 12/30/2005 United Kingdom
Primary
Concomitant
Osteonecrosis Other Serious 7/18/2005 41 Female 1/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Disability 12/6/2005 75 Female 1/9/2006 United Kingdom
Primary
Concomitant
Visual Disturbance Hospitalization 6/21/2003 Male 2/14/2006 Sweden
Primary
Concomitant
Oral Candidiasis Death 10/31/2005 Female 125 lb 3/1/2006 Physician United States
Primary
Concomitant
Osteomyelitis Other Serious 5/24/2005 Female 154 lb 3/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Osteomyelitis Other Serious 5/24/2005 35 Female 4/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Osteomyelitis Other Serious 5/24/2005 35 Female 4/20/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 3/5/2003 52 Female 5/1/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 3/5/2003 52 Female 5/11/2006 Canada
Primary
Secondary
Concomitant
Cardiac Failure Death 4/15/2006 60 Male 128 lb 6/14/2006 Physician Spain
Primary
Concomitant
Arteriosclerosis Death 4/17/2006 Female 112 lb 7/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Osteomyelitis Other Serious 5/24/2005 35 Female 8/8/2006 Denmark
Primary
Secondary
Concomitant
Wound Hospitalization 7/14/2006 Male 242 lb 8/25/2006 Pharmacist United States
Primary
Concomitant
Hypoaesthesia Hospitalization 6/15/2006 Female 11/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Breast Cancer Death 12/21/2005 Female 143 lb 11/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Disorder Other Serious 42 Male 11/6/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Death Female 154 lb 11/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Death Female 154 lb 11/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Death Female 154 lb 11/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Death Female 154 lb 11/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Death Female 154 lb 11/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 42 Male 12/4/2006 United Kingdom
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 68 Female 12/7/2006 Canada
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 6/25/2006 37 Female 121 lb 12/30/2006 Physician Colombia
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 6/25/2006 37 Female 121 lb 1/8/2007 Other Health Professional Colombia
Primary
Concomitant
Urinary Tract Infection Life Threatening 6/25/2006 Female 121 lb 1/18/2007 Physician Colombia
Primary
Secondary
Concomitant
Sepsis Death Female 154 lb 1/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Other Serious 5/24/2005 Female 154 lb 1/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urosepsis Life Threatening 6/25/2006 37 Female 121 lb 1/25/2007 Other Health Professional Colombia
Primary
Concomitant
Renal Tubular Disorder Other Serious 23 Male 5/18/2007 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 5/24/2005 36 Female 6/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Other Serious 5/24/2005 36 Female 6/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Drug Interaction Hospitalization 73 Male 8/13/2007
Primary
Secondary
Concomitant
Visual Disturbance Hospitalization 6/21/2003 Male 8/14/2007 Sweden
Primary
Concomitant
Pulmonary Fibrosis Life Threatening Male 8/31/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Asthma Hospitalization 3/19/2007 Female 9/4/2007 Pharmacist Switzerland
Primary
Concomitant
Post Procedural Haemorrhage Death 61 Male 9/18/2007 Other Health Professional United States
Primary
Concomitant
Melaena Hospitalization 9/13/2007 Male 10/8/2007 Other Health Professional Japan
Primary
Concomitant
Vomiting Death 9/29/2007 63 Male 10/18/2007 Other Health Professional United States
Primary
Concomitant
Transplant Rejection Death 2/14/2006 61 Male 10/23/2007 Other Health Professional United States
Primary
Concomitant
Injection Site Pain 7/1/2007 Female 105 lb 12/14/2007 Consumer United States
Primary
Concomitant
Anaemia Other Serious 70 Male 12/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaemia Other Serious 70 Male 12/21/2007 United Kingdom
Primary
Secondary
Concomitant
Anaemia Other Serious 70 Male 12/21/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/1/2008 61 Female 169 lb 2/25/2008 France
Primary
Secondary
Concomitant
Swelling 7/1/2007 Female 105 lb 3/14/2008 United States
Primary
Concomitant
Pain 11/1/2007 Female 142 lb 3/15/2008 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 12/1/2007 Female 150 lb 6/27/2008 Brazil
Primary
Concomitant
Lung Disorder Hospitalization 2/7/2001 Male 209 lb 7/31/2008 Physician Australia
Primary
Secondary
Concomitant
International Normalised Ratio Decreased Other Serious Female 8/28/2008
Primary
Secondary
Concomitant
Injection Site Nodule 8/27/2008 Female 120 lb 9/13/2008 Consumer United States
Primary
Concomitant
Drug Interaction Hospitalization 73 Male 8/6/2007 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/1/2007 Female 150 lb 10/7/2008 Brazil
Primary
Concomitant
Visual Impairment Required Intervention 1/9/2008 21 Female 106 lb 10/7/2008 Pharmacist United States
Primary
Secondary
Concomitant
Osteomyelitis Other Serious 5/24/2005 35 Female 10/22/2008 Denmark
Primary
Secondary
Concomitant
Rash Maculo-papular Life Threatening 3/26/2005 Male 177 lb 2/13/2009 Physician United States
Primary
Secondary
Concomitant
Lung Disorder Other Serious 1/16/2009 Female 3/11/2009 Physician United Kingdom
Primary
Concomitant
Asthenia Other Serious Male 183 lb 3/19/2009 Other Health Professional Canada
Primary
Concomitant
Musculoskeletal Stiffness 6/13/2008 58 Male 158 lb 1/8/2009 United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 12/18/2008 79 Male 151 lb 4/7/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Lung Disorder Other Serious 1/16/2009 Female 4/8/2009 Physician United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Death 12/18/2008 Male 151 lb 4/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 12/18/2008 79 Male 151 lb 4/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 12/18/2008 79 Male 4/22/2009 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 12/18/2008 79 Male 4/25/2009 United Kingdom
Primary
Secondary
Concomitant
Pain In Jaw 1/23/2009 60 Female 145 lb 5/15/2009 Consumer United States
Primary
Concomitant
Blood Pressure Decreased Other Serious Male 183 lb 8/21/2009 Other Health Professional Canada
Primary
Concomitant
Lymphocyte Count Decreased Disability 1/4/2009 63 Male 154 lb 9/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Wrong Technique In Drug Usage Process 8/27/2008 Female 120 lb 9/12/2009 Consumer United States
Primary
Concomitant
Resorption Bone Increased Hospitalization 12/31/2008 Male 190 lb 9/16/2009 Consumer
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/10/2007 78 Male 123 lb 9/17/2009 Consumer Japan
Primary
Concomitant
Weight Decreased Hospitalization 10/1/2009 Male 155 lb 10/11/2009 Other Health Professional United States
Primary
Concomitant
Headache 4/4/2008 54 Female 154 lb 10/24/2008 Canada
Primary
Secondary
Concomitant
Femur Fracture Other Serious 61 Female 11/13/2009 Sweden
Primary
Concomitant
Pyrexia Hospitalization 8/1/2006 22 Female 12/18/2009 Brazil
Primary
Concomitant
Hypotonia Other Serious 6/1/2008 67 Male 1/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Toxic Epidermal Necrolysis Death 12/18/2008 79 Male 151 lb 1/19/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Dysphagia Hospitalization 1/1/2010 Female 222 lb 1/26/2010 Other Health Professional United States
Primary
Concomitant
Urinary Incontinence Hospitalization 1/1/2006 22 Female 1/26/2010 Brazil
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 12/18/2008 1/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotonia Other Serious 67 Male 1/21/2010 United Kingdom
Primary
Secondary
Toxic Epidermal Necrolysis Death 12/18/2008 79 Male 150 lb 2/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myopericarditis Hospitalization 9/4/2009 Female 130 lb 2/4/2010 Consumer United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Death 12/18/2008 79 Male 2/1/2010 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 12/18/2008 79 Male 2/1/2010 United Kingdom
Primary
Secondary
Concomitant
Leukopenia Other Serious 46 Female 3/4/2010
Primary
Secondary
Concomitant
Myopericarditis Hospitalization 9/4/2009 Female 130 lb 3/15/2010 Consumer United Kingdom
Primary
Concomitant
Vomiting Other Serious 1/1/2006 22 Female 3/18/2010 Brazil
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 5/7/2009 Male 198 lb 3/19/2010 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Female 143 lb 3/30/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Infusion Related Reaction Hospitalization 3/1/2010 64 Male 175 lb 4/8/2010 Other Health Professional United States
Primary
Concomitant
Mania Other Serious 60 Male 4/16/2010 Physician Switzerland
Primary
Concomitant
Liver Transplant Rejection Other Serious 12/16/2008 4/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 29 Female 143 lb 5/20/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 29 Female 143 lb 6/4/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 5/9/2010 82 Male 6/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gallbladder Operation Hospitalization 5/18/2010 33 Female 6/29/2010 Brazil
Primary
Concomitant
Oedema Peripheral Hospitalization 6/26/2010 25 Female 198 lb 7/23/2010 Consumer United States
Primary
Concomitant
Tendon Rupture Other Serious 6/6/2010 49 Female 8/9/2010 United Kingdom
Primary
Concomitant
Emphysema Hospitalization 1/1/2008 63 Male 165 lb 9/30/2010 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Death 12/18/2008 79 Male 10/11/2010 United Kingdom
Primary
Secondary
Concomitant
Teratogenicity Congenital Anomaly 4/25/2009 10/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Teratogenicity 10/25/2010 United Kingdom
Primary
Secondary
Concomitant
Colon Cancer Hospitalization 1/1/2008 63 Male 165 lb 10/27/2010 Consumer United States
Primary
Concomitant
Teratogenicity Other Serious 10/28/2010 Other Health Professional
Primary
Secondary
Concomitant
Maternal Drugs Affecting Foetus Other Serious 10/28/2010 Other Health Professional
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 6/26/2010 25 Female 198 lb 11/12/2010 Physician United States
Primary
Concomitant
Teratogenicity Congenital Anomaly 4/25/2009 11/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Hospitalization 9/8/2010 61 Male 172 lb 1/12/2011 Physician United Kingdom
Primary
Concomitant
Drug Effect Decreased Hospitalization 12/16/2010 51 Female 1/10/2011 Other Health Professional Japan
Primary
Concomitant
Oral Pain 6/22/2010 72 Female 1/29/2011 Consumer United States
Primary
Concomitant
Tooth Infection 72 Female 1/30/2011 Consumer United States
Primary
Concomitant
Muscle Spasms 10/1/2010 47 Female 177 lb 1/30/2011 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 9/8/2010 61 Male 172 lb 1/31/2011 Physician United Kingdom
Primary
Concomitant
Renal Failure Chronic Life Threatening 9/8/2010 61 Male 172 lb 2/4/2011 Physician United Kingdom
Primary
Concomitant
Urinary Casts Present Other Serious 1/1/2006 29 Female 143 lb 2/4/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Life Threatening 9/8/2010 61 Male 172 lb 2/14/2011 Physician United Kingdom
Primary
Concomitant
Lung Disorder Hospitalization 3/1/2009 58 Female 134 lb 4/7/2011 Physician Germany
Primary
Concomitant
Fall Other Serious 3/16/2011 66 Male 3/29/2011 Consumer United States
Primary
Concomitant
Impaired Healing Hospitalization 9/6/2010 29 Male 4/18/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Aplastic Anaemia Hospitalization 3/2/2011 83 Female 5/3/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 11/30/2010 82 Female 5/12/2011 Physician United States
Primary
Concomitant
Haemoptysis Hospitalization 3/14/2011 42 Male 101 lb 6/1/2011 Physician Japan
Primary
Concomitant
Actinomycosis Other Serious 5/9/2011 59 Female 152 lb 6/2/2011 Physician United States
Primary
Concomitant
Haemoptysis Hospitalization 3/14/2011 42 Male 101 lb 6/14/2011 Physician Japan
Primary
Concomitant
Corneal Graft Rejection Disability 6/21/2009 75 Female 6/16/2011 Other Health Professional United Kingdom
Primary
Concomitant
Lymphadenopathy Other Serious 5/30/2011 35 Male 6/16/2011 Physician Belgium
Primary
Concomitant
Lymphadenopathy Hospitalization 5/30/2011 35 Male 6/17/2011 Physician Belgium
Primary
Concomitant
Groin Abscess Other Serious 5/30/2011 35 Male 143 lb 6/27/2011 Physician Belgium
Primary
Concomitant
Pyrexia Hospitalization 3/14/2011 42 Male 101 lb 7/6/2011 Physician Japan
Primary
Concomitant
Groin Abscess Hospitalization 5/30/2011 35 Male 143 lb 7/7/2011 Physician Belgium
Primary
Concomitant
Cardiac Arrest Life Threatening 9/8/2010 61 Male 172 lb 7/8/2011 Physician United Kingdom
Primary
Concomitant
Cardiac Arrest Life Threatening 9/8/2010 61 Male 172 lb 7/11/2011 Physician United Kingdom
Primary
Concomitant
Cardiac Arrest Hospitalization 9/8/2010 61 Male 172 lb 7/12/2011 Physician United Kingdom
Primary
Concomitant
Hallucination Other Serious 72 Male 7/13/2011 Consumer New Zealand
Primary
Concomitant
Atrial Fibrillation Hospitalization 9/8/2010 61 Male 172 lb 7/22/2011 Physician United Kingdom
Primary
Concomitant
Erythema Other Serious 6/21/2006 66 Male 165 lb 7/28/2011 Lawyer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/14/2011 42 Male 101 lb 8/10/2011 Physician Japan
Primary
Concomitant
Clostridium Test Positive Other Serious 26 Female 8/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Hallucination Other Serious 72 Male 9/12/2011 Physician New Zealand
Primary
Concomitant
Groin Abscess Hospitalization 5/30/2011 35 Male 143 lb 9/29/2011 Physician Belgium
Primary
Concomitant
Fistula Discharge Other Serious Male 200 lb 10/5/2011 Physician Canada
Primary
Concomitant
Pyrexia Hospitalization 3/14/2011 42 Male 101 lb 10/11/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 3/14/2011 42 Male 101 lb 10/19/2011 Physician Japan
Primary
Concomitant
Haemorrhoids Other Serious 10/31/2007 35 Female 116 lb 10/19/2011 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 9/17/2011 78 Male 172 lb 11/11/2011 Other Health Professional Germany
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/29/2009 60 Male 172 lb 12/9/2011 Physician United Kingdom
Primary
Concomitant
Convulsion Other Serious 11/25/2011 50 Male 12/14/2011 Physician Germany
Primary
Concomitant
Haemoptysis Hospitalization 5/6/2010 70 Female 1/3/2012 Physician Japan
Primary
Secondary
Concomitant

Drug Data