Alendronate Sodium combined with Aspirin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Serotonin Syndrome 75 Female 12/30/2005 United Kingdom
Primary
Concomitant
Von Willebrand's Factor Multimers Abnormal Other Serious 8/1/2005 57 Female 150 lb 12/30/2005 Argentina
Primary
Concomitant
Serotonin Syndrome Disability 12/6/2005 75 Female 1/9/2006 United Kingdom
Primary
Concomitant
Somnolence Hospitalization 9/4/2005 89 Male 170 lb 1/10/2006 United States
Primary
Concomitant
Spinal Compression Fracture Hospitalization 9/26/2005 Female 1/17/2006 Belgium
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/15/2005 Female 159 lb 1/18/2006 Germany
Primary
Concomitant
Pruritus Death 7/22/2004 Male 187 lb 1/25/2006 United Kingdom
Primary
Concomitant
Lethargy Other Serious 12/27/2005 64 Female 253 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Hyperglycaemia Hospitalization 1/25/2006 78 Female 196 lb 2/3/2006 Other Health Professional United States
Primary
Concomitant
Oral Candidiasis Death 10/31/2005 Female 125 lb 3/1/2006 Physician United States
Primary
Concomitant
Tongue Disorder Other Serious 93 Female 3/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 32 Female 132 lb 3/9/2006 United States
Primary
Concomitant
Fall Hospitalization 82 Female 3/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Methaemoglobinaemia Hospitalization 1/1/2005 32 Female 3/29/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 3/2/2006 39 Female 4/5/2006 Spain
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 11/1/2005 Male 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Shock Life Threatening 1/21/2006 79 Female 5/4/2006 Japan
Primary
Secondary
Syncope Required Intervention 12/1/2005 77 Female 12/2/2005 Pharmacist United States
Primary
Concomitant
Ulcer Other Serious 12/5/2005 73 Male 194 lb 12/6/2005 Other Health Professional United States
Primary
Concomitant
Tearfulness Hospitalization 3/8/2006 Female 6/30/2006 Other Health Professional France
Primary
Secondary
Concomitant
Chest Pain Hospitalization 4/10/2004 69 Female 7/6/2006 Consumer Italy
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 7/15/2006 57 Female 212 lb 7/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/15/2006 57 Female 212 lb 7/19/2006 Pharmacist United States
Primary
Concomitant
Oesophagitis Hospitalization 4/23/2006 84 Male 137 lb 7/23/2006 Pharmacist United States
Primary
Concomitant
Granulocytopenia Required Intervention 4/7/2006 81 Female 5/23/2006 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 75 Female 6/27/2006 Consumer United States
Primary
Concomitant
Transplant Rejection Hospitalization 4/17/2006 55 Male 261 lb 5/10/2006 Pharmacist United States
Primary
Concomitant
Retroperitoneal Haemorrhage Other Serious 9/17/2004 74 Female 141 lb 8/28/2006 Australia
Primary
Secondary
Concomitant
Wound Hospitalization 7/14/2006 Male 242 lb 8/25/2006 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/10/2005 85 Female 8/25/2006 United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/10/2005 85 Female 8/28/2006 United Kingdom
Primary
Secondary
Concomitant
Vasculitis Other Serious 11/15/2005 Female 111 lb 9/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Face Hospitalization 5/24/2006 Female 9/7/2006 Physician United States
Primary
Concomitant
Panic Attack Hospitalization 4/11/2005 Female 128 lb 9/14/2006 Consumer Canada
Primary
Concomitant
Vomiting Hospitalization 61 Female 9/25/2006
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 8/3/2006 82 Female 9/27/2006 Consumer United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 4/15/2005 87 Male 134 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/28/2006 82 Male Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Death Female 123 lb 10/13/2006 Consumer United Kingdom
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/7/2006 Female 10/13/2006 Consumer United States
Primary
Concomitant
Vestibular Disorder Hospitalization 9/19/2006 57 Male 269 lb 10/6/2006 Other Health Professional United States
Primary
Concomitant
Sedation Hospitalization 9/19/2006 57 Male 269 lb 10/9/2006 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Required Intervention 7/27/2006 68 Male 232 lb 8/22/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 7/19/2006 85 Female 11/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Restless Legs Syndrome Hospitalization 9/19/2006 57 Male 269 lb 10/23/2006 Other Health Professional United States
Primary
Concomitant
Myocardial Ischaemia Death Female 126 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Viral Infection Hospitalization 9/19/2006 57 Male 269 lb 11/10/2006 Other Health Professional United States
Primary
Concomitant
Bone Marrow Failure Other Serious 68 Female 12/7/2006 Canada
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 4/15/2006 Male 12/22/2006 United Kingdom
Primary
Concomitant
Arthritis Bacterial Other Serious 12/20/2006 68 Female 1/4/2007 Consumer Argentina
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 1/8/2007
Primary
Secondary
Concomitant
Arthritis Other Serious 12/20/2006 68 Female 1/11/2007 Consumer Argentina
Primary
Secondary
Concomitant
Pneumonia Other Serious 7/5/2006 152 lb 1/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Synovial Cyst Other Serious 1/1/2006 Female 111 lb 1/19/2007 Physician United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2006 Male 190 lb 1/27/2007 Consumer Canada
Primary
Concomitant
Troponin Increased Hospitalization 11/10/2006 Female 2/2/2007 Physician Belgium
Primary
Concomitant
Prescribed Overdose Other Serious 1/1/2006 Male 317 lb 2/2/2007 Pharmacist Denmark
Primary
Interacting
Hypoaesthesia Hospitalization 11/1/2006 Female 150 lb 2/6/2007 Consumer United States
Primary
Concomitant
Ankle Fracture Hospitalization 8/17/2004 Female 112 lb 2/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Treatment Noncompliance Hospitalization 10/6/2006 77 Male 123 lb 12/12/2006 Pharmacist United States
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 7/5/2006 152 lb 2/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hypoglycaemia Hospitalization 12/16/2006 58 Male 2/15/2007 Pharmacist United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Required Intervention 10/10/2006 83 Male 135 lb 10/24/2006 Pharmacist United States
Primary
Concomitant
Arterial Occlusive Disease Hospitalization 5/3/2005 Male 181 lb 3/7/2007 Consumer United Kingdom
Primary
Concomitant
Vasculitis Hospitalization 12/1/2005 Female 132 lb 3/8/2007 Consumer United Kingdom
Primary
Concomitant
Yellow Skin Hospitalization 3/16/2007 81 Male 134 lb 3/29/2007 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/23/2006 Male 110 lb 3/11/2007 Pharmacist United States
Primary
Concomitant
Oesophageal Ulcer Haemorrhage Other Serious 63 Female 4/30/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 2/21/2007 77 Female 5/2/2007 Spain
Primary
Secondary
Concomitant
Hypotension Hospitalization 10/20/2004 Male 6/22/2007 Pharmacist United States
Primary
Secondary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious 5/9/2007 Female 151 lb 6/25/2007 Physician United Kingdom
Primary
Concomitant
Tremor Hospitalization 3/14/2006 77 Male 6/27/2007 Physician Finland
Primary
Concomitant
Tremor Hospitalization 3/14/2006 77 Male 6/15/2007 United Kingdom
Primary
Concomitant
Tremor Hospitalization 3/14/2006 77 Male 6/15/2007 United Kingdom
Primary
Concomitant
Sinusitis Other Serious 3/1/2005 52 Male 261 lb 7/12/2007 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 6/11/2007 Male 101 lb 7/13/2007 Physician United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 7/5/2006 Male 152 lb 7/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Wheezing Disability 1/29/2007 Female 7/25/2007 Pharmacist United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 4/28/2004 Male 203 lb 7/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Syringomyelia Death 2/15/2005 Male 154 lb 7/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vasculitis Other Serious 11/15/2005 Female 111 lb 8/6/2007 Physician United Kingdom
Primary
Concomitant
Drug Interaction Hospitalization 73 Male 8/13/2007
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3/9/2007 70 Male 8/15/2007 Germany
Primary
Concomitant
Sepsis Other Serious 11/4/2004 Female 8/21/2007 Other Health Professional Sweden
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/18/2007 Female 168 lb 8/24/2007 Physician Germany
Primary
Concomitant
Urinary Tract Infection Enterococcal Hospitalization 4/19/2007 Female 154 lb 8/24/2007 Physician Germany
Primary
Concomitant
Raynaud's Phenomenon Hospitalization 1/1/2001 60 Female 8/30/2007 Physician Canada
Primary
Secondary
Concomitant
Pharyngeal Oedema Hospitalization Female 9/5/2007 Pharmacist New Zealand
Primary
Concomitant
Vision Blurred 60 Female 7/20/2007 United States
Primary
Concomitant
Regurgitation Hospitalization 6/6/2007 81 Female 103 lb 9/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/21/2007 84 Male 119 lb 9/14/2007 Physician Australia
Primary
Concomitant
Tremor Hospitalization 3/14/2006 77 Male 9/19/2007 Physician Finland
Primary
Concomitant
B-cell Lymphoma Death 1/15/2007 Male 185 lb 9/19/2007 United Kingdom
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 73 Female 9/24/2007 Pharmacist United States
Primary
Concomitant
Interacting
Post Procedural Haemorrhage Death 61 Male 9/18/2007 Other Health Professional United States
Primary
Concomitant
Tremor Hospitalization 3/14/2006 77 Male 9/11/2007 United Kingdom
Primary
Concomitant
Blood Glucose Decreased Hospitalization 4/15/2007 75 Male 8/22/2007 Consumer United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 8/29/2007 52 Female 321 lb 9/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 5/31/2006 73 Female 10/3/2007 Other Health Professional France
Primary
Concomitant
Interacting
Tremor Hospitalization 11/1/2004 85 Female 10/8/2007 Physician Australia
Primary
Concomitant
Melaena Hospitalization 9/13/2007 Male 10/8/2007 Other Health Professional Japan
Primary
Concomitant
Transplant Rejection Death 2/14/2006 61 Male 10/23/2007 Other Health Professional United States
Primary
Concomitant
Erythema Other Serious 6/20/2007 Female 139 lb 11/9/2007 Physician Poland
Primary
Concomitant
Rectal Haemorrhage Other Serious 11/4/2007 Female 11/12/2007 Consumer Canada
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 6/25/2007 85 Male 11/7/2007 Pharmacist United States
Primary
Secondary
Upper Gastrointestinal Haemorrhage Life Threatening 6/25/2007 85 Male 11/20/2007 Pharmacist United States
Primary
Secondary
Pruritus Hospitalization 9/29/2007 79 Female 139 lb 11/28/2007 Pharmacist United States
Primary
Concomitant
Myocardial Ischaemia Other Serious Male 168 lb 12/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Erythema 6/20/2007 Female 139 lb 1/3/2008 Physician Poland
Primary
Concomitant
Rectal Haemorrhage Life Threatening 12/22/2007 63 Female 1/10/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 53 Female 108 lb 1/24/2008 Physician Japan
Primary
Concomitant
Pancreatitis Hospitalization 4/14/2007 Male 225 lb 1/24/2008 United Kingdom
Primary
Concomitant
Rectal Haemorrhage Life Threatening 12/22/2007 63 Female 1/21/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemorrhage Intracranial Death 4/7/2005 79 Female 11/29/2007 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 1/26/2008 Male 97 lb 2/8/2008 United States
Primary
Concomitant
Pain In Extremity Hospitalization 10/1/2007 67 Male 2/8/2008 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3/9/2007 70 Male 2/8/2008 Germany
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 12/24/2007 66 Female 86 lb 2/11/2008 Consumer Japan
Primary
Concomitant
Diarrhoea Hospitalization 53 Female 108 lb 2/12/2008 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Other Serious 4/4/2006 Male 2/12/2008 United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 1/18/2008 85 Female 2/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 10/1/2007 Male 195 lb 2/19/2008 Physician United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 12/22/2007 63 Female 2/12/2008 United States
Primary
Secondary
Concomitant
Metastatic Gastric Cancer Death 1/15/2007 Male 185 lb 2/22/2008 United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 11/1/2007 Female 160 lb 2/22/2008 Canada
Primary
Concomitant
Factor Viii Deficiency Other Serious 12/15/2007 Female 117 lb 2/22/2008 United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage 1/21/2008 77 Male 170 lb 2/26/2008 Pharmacist United States
Primary
Secondary
Prostatic Specific Antigen Increased 1/1/2006 74 Male 212 lb 1/10/2008 Consumer United States
Primary
Concomitant
Rash Other Serious 8/1/2007 Female 170 lb 3/5/2008 United States
Primary
Concomitant
Torsade De Pointes Hospitalization 2/8/2008 79 Female 3/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Streptococcal Sepsis Other Serious 4/1/2007 Female 190 lb 3/7/2008 United Kingdom
Primary
Secondary
Concomitant
Pseudomonas Infection Disability 11/1/2005 Female 194 lb 3/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tuberculosis Gastrointestinal Other Serious Male 170 lb 3/14/2008 Canada
Primary
Concomitant
Muscular Weakness 1/1/2008 Female 146 lb 3/15/2008 United States
Primary
Concomitant
Immune Reconstitution Syndrome Other Serious 9/10/2007 27 Male 3/21/2008 Physician United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 11/4/2007 Female 3/25/2008 Physician Canada
Primary
Secondary
Concomitant
Tremor Hospitalization 3/14/2006 77 Male 4/3/2008 Physician Finland
Primary
Concomitant
Tremor Hospitalization 3/14/2006 77 Male 3/27/2008 United Kingdom
Primary
Concomitant
Immune Reconstitution Syndrome Other Serious 9/10/2007 27 Male 4/18/2008 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 4/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 82 Female 5/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wound Hospitalization 9/1/2006 Female 5/2/2008 Consumer United States
Primary
Concomitant
Neuropathy Peripheral Hospitalization 12/24/2007 66 Female 99 lb 5/5/2008 Consumer Japan
Primary
Concomitant
Pancreatitis Hospitalization 82 Female 5/2/2008 United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Other Serious 82 Female 5/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatitis Fulminant Other Serious 5/4/2008 75 Female 5/9/2008 Physician Japan
Primary
Concomitant
Haemophilia Hospitalization 12/1/2007 89 Female 5/20/2008 Physician Japan
Primary
Concomitant
Renal Failure Life Threatening 5/2/2008 75 Female 93 lb 5/27/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Life Threatening 5/2/2008 75 Female 93 lb 6/3/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Life Threatening 5/2/2008 75 Female 93 lb 6/4/2008 Physician Japan
Primary
Secondary
Concomitant

Drug Data