Alendronate Sodium combined with Amitriptyline Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Fibrosis Hospitalization 8/1/2005 Female 1/5/2006 Germany
Primary
Secondary
Concomitant
Septic Shock Other Serious 3/1/2005 Female 1/20/2006 Physician United Kingdom
Primary
Concomitant
Peripheral Vascular Disorder Hospitalization 6/15/2005 Male 2/2/2006 United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 11/4/2005 Female 2/9/2006 United Kingdom
Primary
Concomitant
Rash Life Threatening 11/13/2005 45 Female 140 lb 2/7/2006 United States
Primary
Concomitant
Peripheral Vascular Disorder Hospitalization 6/15/2005 Male 2/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Umbilical Hernia Other Serious 11/15/2005 Female 238 lb 2/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Drug Interaction Other Serious 55 Male 3/10/2006 Physician United Kingdom
Primary
Concomitant
Interacting
Oxygen Saturation Decreased Other Serious 32 Female 132 lb 3/9/2006 United States
Primary
Concomitant
Methaemoglobinaemia Hospitalization 1/1/2005 32 Female 3/29/2006 Physician United States
Primary
Secondary
Concomitant
Myopathy Other Serious 55 Male 4/10/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Swelling Face Other Serious 55 Male 4/17/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Myopathy Required Intervention 55 Male 4/13/2006 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 11/1/2005 Male 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rash Required Intervention 11/13/2005 45 Female 140 lb 5/2/2006 United States
Primary
Concomitant
Drug Interaction Other Serious 55 Male 5/9/2006 Physician United Kingdom
Primary
Concomitant
Interacting
Surgery Other Serious 6/15/2005 Male 6/16/2006 Consumer United Kingdom
Primary
Concomitant
Pemphigoid Other Serious 12/1/2005 69 Female 8/29/2006 Pharmacist United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 3/15/2006 Female 146 lb 11/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Venous Pressure Jugular Increased Other Serious Female 142 lb 11/30/2006 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Death 12/31/2006 Female 134 lb 1/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Venous Pressure Jugular Increased Other Serious 3/15/2006 Female 142 lb 1/24/2007 Physician United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 3/15/2006 Female 146 lb 1/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pharyngeal Oedema Other Serious 9/11/2006 73 Male 176 lb 9/18/2006 Pharmacist United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/6/2006 Female 212 lb 2/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Thymus Enlargement Hospitalization 1/1/2005 Female 118 lb 3/16/2007 Physician Canada
Primary
Concomitant
Diarrhoea Hospitalization 9/30/2005 Female 207 lb 3/30/2007 Consumer United Kingdom
Primary
Concomitant
Thymus Enlargement Hospitalization 1/1/2005 Female 118 lb 4/2/2007 Physician Canada
Primary
Concomitant
Surgery Death 12/31/2006 Female 134 lb 4/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sensory Disturbance Life Threatening 5/2/2007 63 Male 170 lb 5/24/2007 Physician
Primary
Concomitant
Venous Pressure Jugular Increased Other Serious 3/15/2006 Female 146 lb 6/14/2007 Physician United Kingdom
Primary
Concomitant
Venous Pressure Jugular Increased Other Serious 3/15/2006 Female 146 lb 6/19/2007 Physician United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 5/9/2007 Female 150 lb 6/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious Female 6/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 5/28/2006 Female 207 lb 7/13/2007 United Kingdom
Primary
Concomitant
Vomiting Other Serious Female 7/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hip Arthroplasty Hospitalization 6/20/2007 Female 110 lb 7/18/2007 Canada
Primary
Concomitant
Treatment Noncompliance Death 6/2/2007 7/13/2007 United Kingdom
Primary
Concomitant
Surgery Death 12/31/2006 Female 134 lb 7/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 11/4/2005 Male 7/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Stasis Dermatitis Hospitalization 11/9/2004 Male 192 lb 7/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hip Arthroplasty Hospitalization 6/20/2007 Female 110 lb 7/30/2007 Canada
Primary
Concomitant
Drug Interaction Hospitalization 73 Male 8/13/2007
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/1/2007 78 Female 8/21/2007 Consumer Germany
Primary
Concomitant
Premature Baby Other Serious 5/9/2002 Male 8/29/2007 United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 12/15/2006 Female 170 lb 9/10/2007 United Kingdom
Primary
Concomitant
Clavicle Fracture Hospitalization 12/21/2006 Male 130 lb 9/14/2007 United Kingdom
Primary
Concomitant
Somnolence Hospitalization 9/29/2006 70 Female 9/21/2007 New Zealand
Primary
Concomitant
Somnolence Other Serious 9/22/2007 45 Female 10/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pleurisy Hospitalization 5/9/2007 Male 214 lb 10/11/2007 United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 11/4/2005 Male 10/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Hospitalization 9/29/2006 70 Female 10/31/2007 New Zealand
Primary
Concomitant
Nodal Marginal Zone B-cell Lymphoma Other Serious 10/15/2007 Female 152 lb 11/7/2007 United States
Primary
Concomitant
Tremor Other Serious 9/22/2007 Female 141 lb 11/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Hospitalization 7/2/2007 Male 1/21/2008 United Kingdom
Primary
Concomitant
Rash Other Serious 8/1/2007 Female 170 lb 3/5/2008 United States
Primary
Concomitant
Streptococcal Sepsis Other Serious 4/1/2007 Female 190 lb 3/7/2008 United Kingdom
Primary
Secondary
Concomitant
Viral Infection Other Serious 1/9/2008 Female 154 lb 3/13/2008 Consumer Brazil
Primary
Concomitant
Ulcer Other Serious 5/10/2007 Female 112 lb 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Hospitalization 7/2/2007 Male 5/30/2008 United Kingdom
Primary
Concomitant
Gallbladder Cancer Life Threatening 4/30/2008 Male 192 lb 6/27/2008 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Death Female 132 lb 8/15/2008 United Kingdom
Primary
Concomitant
Septic Shock Other Serious 5/31/2008 69 Female 77 lb 8/14/2008 Physician Japan
Primary
Secondary
Concomitant
Hospitalisation Hospitalization Female 10/10/2008 Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 6/11/2008 60 Female 226 lb 10/20/2008 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/11/2008 60 Female 226 lb 10/31/2008 United States
Primary
Concomitant
Aphonia Other Serious 10/10/2008 76 Female 11/26/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 7/16/2008 Female 154 lb 11/30/2008 United Kingdom
Primary
Concomitant
Cerebrovascular Accident Death 1/1/2007 58 Female 11/24/2008 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 6/29/2008 Male 1/13/2009 United Kingdom
Primary
Concomitant
Infection Hospitalization 8/19/2007 Male 1/13/2009 United Kingdom
Primary
Concomitant
Infective Exacerbation Of Chronic Obstructive Airways Disease Hospitalization 8/19/2007 Male 1/14/2009 United Kingdom
Primary
Concomitant
Hypotension Other Serious 12/16/2008 70 Female 1/20/2009 Physician United Kingdom
Primary
Concomitant
Hypotension Other Serious 12/16/2008 70 Female 1/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral 12/1/2005 Female 212 lb 1/20/2009 Physician United States
Primary
Concomitant
Urinary Retention 10/15/2008 Female 212 lb 1/20/2009 Physician United States
Primary
Concomitant
Death Other Serious 61 Female 187 lb 1/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Disorder Other Serious 11/1/2008 Female 119 lb 2/5/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious Female 187 lb 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Osteonecrosis Other Serious 8/4/2008 94 Female 5/2/2009 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/24/2009 Female 6/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 55 Male 7/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Drug Interaction Other Serious 55 Male 7/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Ventricular Hypokinesia Life Threatening 7/30/2009 48 Male 157 lb 9/18/2009 Physician Japan
Primary
Concomitant
Pancytopenia Life Threatening 7/30/2009 48 Male 157 lb 10/6/2009 Physician Japan
Primary
Concomitant
Product Quality Issue 6/25/2009 60 Female 1/4/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 3/1/2008 Female 128 lb 1/22/2010 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2010 Female 132 lb 2/12/2010 Physician United Kingdom
Primary
Concomitant
Epistaxis Other Serious 1/22/2010 43 2/5/2010 United Kingdom
Primary
Concomitant
Myopericarditis Hospitalization 9/4/2009 Female 130 lb 3/15/2010 Consumer United Kingdom
Primary
Concomitant
Eczema Other Serious 12/9/2003 Female 128 lb 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Asthma Hospitalization 8/23/2009 75 Female 130 lb 4/26/2010 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 1/1/2009 64 Female 128 lb 8/31/2010 Physician Brazil
Primary
Concomitant
Muscular Weakness Hospitalization 11/20/2009 58 Female 143 lb 9/20/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vaginal Infection 6/1/2010 50 Female 124 lb 10/26/2010 Consumer United States
Primary
Concomitant
Alopecia 2/1/2010 64 Female 11/18/2010 Consumer United States
Primary
Concomitant
Madarosis 4/1/2010 52 Female 11/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Other Serious 1/1/2007 67 Female 163 lb 11/18/2010 Physician
Primary
Secondary
Concomitant
Wound Infection Hospitalization 9/25/2010 70 Female 11/29/2010 Other Health Professional Japan
Primary
Concomitant
Rash 6/22/2010 12/22/2010 Consumer United States
Primary
Concomitant
Panic Attack Other Serious 7/1/2007 67 Female 163 lb 12/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Casts Present Other Serious 1/1/2006 29 Female 143 lb 2/4/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 9/15/2010 70 Female 2/10/2011 Consumer United States
Primary
Concomitant
Tremor Other Serious 82 Female 4/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Septic Shock Hospitalization 5/31/2008 69 Female 77 lb 4/8/2011 Physician Japan
Primary
Secondary
Concomitant
Endophthalmitis Hospitalization 4/10/2011 75 Female 5/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Drug Interaction Hospitalization 82 Female 5/2/2011 Physician United States
Primary
Secondary
Concomitant
Seronegative Arthritis Other Serious 72 Male 6/1/2011 Other Health Professional New Zealand
Primary
Concomitant
Weight Decreased 12/24/2010 49 Female 293 lb 5/11/2011 Consumer United States
Primary
Concomitant
Hypoglycaemia Other Serious 6/11/2011 79 Male 7/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Asthenia Other Serious 2/25/2011 63 Male 7/14/2011 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 11/1/2010 79 Male 88 lb 7/27/2011 Physician Japan
Primary
Concomitant
Interacting
Tendonitis Disability 5/13/2011 73 Female 120 lb 7/12/2011 Other Health Professional United Kingdom
Primary
Concomitant
No Therapeutic Response Hospitalization 72 Male 8/3/2011 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Syncope Other Serious 11/1/2010 79 Male 88 lb 8/10/2011 Physician Japan
Primary
Concomitant
Interacting
Abscess Jaw Hospitalization 80 Female 8/4/2011 Other Health Professional United Kingdom
Primary
Concomitant
Oesophageal Stenosis Hospitalization 80 Female 8/5/2011 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 6/24/2011 59 Female 8/17/2011 Physician France
Primary
Secondary
Concomitant
Economic Problem Death Female 7/29/2011 Other Health Professional United States
Primary
Concomitant
Hyponatraemia Hospitalization 5/31/2008 69 Female 77 lb 8/18/2011 Physician Japan
Primary
Concomitant
Hypotension Hospitalization 6/10/2011 70 Female 143 lb 8/30/2011 Pharmacist United States
Primary
Concomitant
Blood Sodium Decreased Hospitalization 5/13/2011 68 Female 9/28/2011 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 49 Female 134 lb 10/12/2011 Pharmacist United States
Primary
Concomitant
Myalgia Hospitalization 72 Male 11/18/2011 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Asthma Hospitalization 8/23/2009 75 Female 130 lb 12/6/2011 Physician Japan
Primary
Concomitant
Seronegative Arthritis Disability 72 Male 12/6/2011 Other Health Professional New Zealand
Primary
Concomitant
Sinusitis Hospitalization 12/5/2010 56 Female 216 lb 12/12/2011 Physician United States
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 11/22/2011 79 Female 106 lb 12/14/2011 Physician Japan
Primary
Secondary
Concomitant
Femur Fracture Hospitalization 11/22/2011 72 Female 121 lb 12/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Traumatic Fracture Other Serious 11/22/2011 72 Female 121 lb 12/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 11/9/2011 75 Female 12/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Injury Hospitalization 11/22/2011 72 Female 121 lb 12/20/2011 Other Health Professional
Primary
Concomitant
Hyponatraemia Hospitalization 11/22/2011 79 Female 106 lb 12/28/2011 Physician Japan
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 10/30/2011 84 Female 1/27/2012 Other Health Professional France
Primary
Secondary
Concomitant
Culture Urine Positive Hospitalization 58 Female 3/5/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Anaphylactic Reaction Hospitalization 8/10/2011 60 Female 3/22/2012 Physician United States
Primary
Concomitant
Tooth Disorder Other Serious 37 Female 161 lb 4/2/2012 Consumer Brazil
Primary
Concomitant
Dyspnoea Hospitalization 7/30/2009 72 Female 224 lb 5/28/2010 Physician United States
Primary
Concomitant
Pathological Fracture Other Serious 1/1/2009 64 Female 5/3/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Bronchopneumonia Death 10/5/2002 71 Female 161 lb 6/4/2012 Other Health Professional United Kingdom
Primary
Concomitant
Anaemia Postoperative Hospitalization 1/1/2009 64 Female 5/28/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Asthenia Other Serious 2/25/2011 63 Male 7/14/2011 Other Health Professional United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 6/5/2012 69 Female 140 lb 6/28/2012 Other Health Professional United Kingdom
Primary
Concomitant
Cellulitis Hospitalization 5/24/2012 48 Male 215 lb 6/28/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 4/23/2012 66 Female 6/29/2012 Physician United Kingdom
Primary
Concomitant
Drug Ineffective Other Serious 38 Female 157 lb 7/3/2012 Consumer Brazil
Primary
Concomitant
Renal Failure Acute Hospitalization 6/7/2012 56 Male 110 lb 7/3/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/3/2012 7/23/2012 Physician Japan
Primary
Secondary
Concomitant
Tardive Dyskinesia Death 10/5/2002 71 Female 161 lb 7/26/2012 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 7/19/2011 75 Female 121 lb 8/3/2012 Physician Germany
Primary
Secondary
Concomitant

Drug Data