Alendronate Sodium combined with Alprazolam

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Ulcer Hospitalization 1/1/2005 Female 1/26/2006 Hungary
Primary
Concomitant
Vitamin A Increased Required Intervention 2/25/2006 41 Male 140 lb 3/15/2006 Pharmacist United States
Primary
Concomitant
Confusional State Other Serious 81 Female 3/8/2006 Physician Ireland
Primary
Concomitant
Confusional State Other Serious 9/1/2005 81 Female 3/14/2006 Physician Ireland
Primary
Concomitant
Stress Hospitalization 5/1/2006 60 Female 103 lb 6/1/2006 Consumer United States
Primary
Concomitant
Thrombophlebitis Other Serious 72 Female 6/28/2006 Spain
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2006 67 Female 8/1/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Poor Quality Drug Administered Other Serious 7/9/2006 77 Female 8/2/2006 United States
Primary
Concomitant
Drug Interaction Hospitalization 7/1/2006 68 Female 8/23/2006 Physician Switzerland
Primary
Concomitant
Interacting
Poor Quality Drug Administered Other Serious 7/9/2006 77 Female 8/28/2006 United States
Primary
Concomitant
Drug Interaction Hospitalization 7/1/2006 68 Female 8/31/2006 Physician Switzerland
Primary
Concomitant
Interacting
Panic Attack Hospitalization 4/11/2005 Female 128 lb 9/11/2006 Consumer Canada
Primary
Concomitant
Panic Attack Hospitalization 4/11/2005 Female 128 lb 9/14/2006 Consumer Canada
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/7/2006 Female 10/13/2006 Consumer United States
Primary
Concomitant
Sepsis Other Serious 1/1/2006 67 Female 10/19/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 8/24/2006 Female 189 lb 10/20/2006 Physician United States
Primary
Concomitant
Sepsis Other Serious 1/1/2006 67 Female 11/7/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Drug Interaction Other Serious 11/1/2006 Female 12/21/2006 Pharmacist France
Primary
Concomitant
Interacting
Paradoxical Drug Reaction Hospitalization 1/24/2007 78 Female 112 lb 1/26/2007 Pharmacist United States
Primary
Concomitant
Hypoaesthesia Hospitalization 11/1/2006 Female 150 lb 2/6/2007 Consumer United States
Primary
Concomitant
Hypoaesthesia Hospitalization 11/1/2006 Female 150 lb 2/14/2007 Physician United States
Primary
Concomitant
Drug Interaction Other Serious 11/1/2006 Female 4/14/2007 Pharmacist France
Primary
Concomitant
Interacting
T-cell Lymphoma Other Serious 3/17/2007 Female 170 lb 5/4/2007 Physician United States
Primary
Concomitant
Splenomegaly Other Serious 2/1/2007 Female 170 lb 5/15/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 2/1/2007 Female 170 lb 6/1/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 5/27/2007 Female 6/11/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 9/10/2006 49 Female 6/13/2007 Physician United States
Primary
Concomitant
Vascular Calcification Hospitalization 9/26/2006 9/6/2007 Consumer France
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 12/1/2007 Female 1/4/2008 United States
Primary
Concomitant
Rash Hospitalization 7/1/2004 77 Female 127 lb 11/29/2007 Consumer United States
Primary
Concomitant
Serum Sickness Hospitalization 1/1/2007 54 Male 179 lb 1/25/2008 Pharmacist United States
Primary
Concomitant
Tibia Fracture Other Serious 9/22/2007 Female 150 lb 3/6/2008 Canada
Primary
Concomitant
Pain 11/1/2007 Female 142 lb 3/15/2008 Consumer United States
Primary
Concomitant
Pain 2/1/2008 Female 147 lb 3/15/2008 Consumer United States
Primary
Concomitant
Acute Sinusitis 2/1/2008 Female 189 lb 3/15/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/1/2007 Female 170 lb 5/7/2008 Physician United States
Primary
Concomitant
Sleep Disorder Required Intervention 3/26/2008 54 Female 125 lb 5/15/2008 Consumer United States
Primary
Concomitant
Precancerous Skin Lesion Female 6/13/2008 Consumer United States
Primary
Concomitant
Nausea Hospitalization 7/21/2008 Female 154 lb 8/1/2008 Physician Austria
Primary
Concomitant
Nausea Hospitalization 7/21/2008 Female 154 lb 8/8/2008 Physician Austria
Primary
Concomitant
Myocardial Infarction Death 7/30/2008 Female 150 lb 8/15/2008 Canada
Primary
Concomitant
International Normalised Ratio Decreased Other Serious Female 8/28/2008
Primary
Secondary
Concomitant
Nervousness 6/20/2008 Female 146 lb 9/12/2008 United States
Primary
Concomitant
Joint Swelling 7/1/2008 Female 180 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 4/1/2003 Female 10/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 8/1/2007 Female 11/14/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 114 lb 12/26/2008 Pharmacist United States
Primary
Concomitant
Stomatitis Disability 75 Female 4/2/2009 Consumer United States
Primary
Concomitant
Foreign Body Trauma Other Serious 4/6/2009 65 Female 190 lb 4/14/2009 Consumer United States
Primary
Concomitant
Lung Disorder Other Serious 12/18/2008 Female 5/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Depression Other Serious 6/15/2009 Female 106 lb 7/22/2009 Other Health Professional Canada
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 9/8/2009 66 Female 229 lb 10/1/2009 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Required Intervention 8/27/2009 71 Female 96 lb 10/22/2009 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 57 Female 175 lb 10/22/2009 Consumer United States
Primary
Concomitant
Small Cell Lung Cancer Stage Unspecified Other Serious 1/1/2009 Female 11/19/2009 Consumer
Primary
Secondary
Concomitant
Drug Toxicity Hospitalization 11/2/2009 Female 90 lb 11/20/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Required Intervention 8/27/2009 71 Female 96 lb 11/17/2009 Physician United States
Primary
Concomitant
Small Cell Lung Cancer Stage Unspecified Other Serious 1/1/2009 Female 11/30/2009 Consumer
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2010 Female 174 lb 3/18/2010 Consumer United States
Primary
Concomitant
Renal Injury Other Serious 12/1/2008 Female 3/19/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 5/20/2009 Female 3/25/2010 Consumer United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Other Serious 2/1/2010 49 Female 137 lb 4/22/2010 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/26/2010 United States
Primary
Secondary
Concomitant
Drug Toxicity Hospitalization 11/2/2009 50 Female 90 lb 5/7/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 5/20/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 5/27/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/3/2010 United States
Primary
Secondary
Concomitant
Pain Other Serious 2/1/2010 49 Female 137 lb 6/7/2010 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/10/2010 United States
Primary
Secondary
Concomitant
Renal Injury Other Serious 7/24/2008 70 Female 189 lb 6/11/2010 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/14/2010 United States
Primary
Secondary
Concomitant
Pain In Extremity Disability 10/13/2007 44 Female 125 lb 6/18/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/23/2010 United States
Primary
Secondary
Concomitant
Cough Hospitalization 12/29/2009 60 Female 122 lb 7/2/2010 Physician Japan
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 7/7/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 8/2/2010 United States
Primary
Secondary
Concomitant
Cough Hospitalization 12/29/2009 60 Female 122 lb 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
Vertigo Other Serious Female 8/12/2010 Consumer United States
Primary
Concomitant
Kyphosis Hospitalization 12/29/2009 60 Female 122 lb 8/27/2010 Physician Japan
Primary
Secondary
Concomitant
Wound Infection Other Serious 1/1/2009 70 Female 112 lb 9/16/2010 Consumer Brazil
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 9/30/2010 United States
Primary
Secondary
Concomitant
Vomiting 1/1/2010 77 Female 10/7/2010 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 4/1/2005 12/16/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Abnormal 1/1/2007 12/20/2010 Physician United States
Primary
Concomitant
Urticaria Other Serious 11/1/2010 65 Female 139 lb 12/20/2010 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection 5/3/2010 12/21/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection 5/3/2010 12/22/2010 Other Health Professional United States
Primary
Concomitant
Oral Herpes 12/22/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 81 Female 132 lb 12/23/2010 Pharmacist Brazil
Primary
Concomitant
Dysphagia Other Serious 11/1/2010 65 Female 139 lb 3/9/2011 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Other Serious 10/1/2010 79 Female 110 lb 4/15/2011 Physician United States
Primary
Concomitant
Dyspepsia Life Threatening 3/27/2011 64 Female 147 lb 4/9/2011 Consumer United States
Primary
Concomitant
Off Label Use Other Serious 12/1/2008 49 191 lb 5/19/2011 Consumer United States
Primary
Concomitant
Decreased Appetite Other Serious 10/1/2010 79 Female 108 lb 5/26/2011 Physician United States
Primary
Concomitant
Meniscus Lesion Hospitalization 1/1/2008 63 Female 198 lb 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious Female 6/6/2011 Physician United States
Primary
Concomitant
Urinary Tract Infection 2/11/2011 60 Female 115 lb 5/11/2011 Consumer United States
Primary
Concomitant
Cataract Other Serious 12/1/2010 75 Female 6/13/2011 Consumer Brazil
Primary
Secondary
Concomitant
Vertigo Other Serious 5/1/2011 71 Female 6/16/2011 Consumer United States
Primary
Concomitant
Nasopharyngitis Other Serious 1/1/2000 61 Female 6/20/2011 Consumer United States
Primary
Concomitant
Wheezing 56 Female 215 lb 6/21/2011 Consumer United States
Primary
Concomitant
Muscle Spasms Other Serious 10/1/2010 79 Female 108 lb 6/28/2011 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 5/16/2011 56 Female 172 lb 7/5/2011 Consumer United States
Primary
Concomitant
Lichenoid Keratosis Other Serious 1/1/2003 56 Female 155 lb 7/7/2011 Pharmacist United States
Primary
Secondary
Concomitant
Excessive Granulation Tissue Hospitalization 1/1/2003 56 Female 155 lb 8/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Feeling Cold 9/21/2010 63 Female 160 lb 8/5/2011 Consumer United States
Primary
Secondary
Concomitant
Flushing Female 165 lb 8/5/2011 Consumer United States
Primary
Concomitant
Dysplastic Naevus Other Serious 1/1/2003 56 Female 155 lb 8/11/2011 United States
Primary
Secondary
Concomitant
Nasopharyngitis Other Serious 1/1/2000 61 Female 8/18/2011 United States
Primary
Concomitant
Fatigue Other Serious 1/1/2003 56 Female 155 lb 8/20/2011 Consumer United States
Primary
Secondary
Concomitant
Tendon Disorder Other Serious 1/1/2003 56 Female 155 lb 8/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Anger Other Serious 1/1/2011 71 Female 10/7/2011 Consumer United States
Primary
Concomitant
Escherichia Test Positive Hospitalization 9/27/2011 62 Female 10/18/2011 Physician Japan
Primary
Secondary
Haemorrhoids Other Serious 10/31/2007 35 Female 116 lb 10/19/2011 Consumer United States
Primary
Concomitant
Fractured Sacrum Hospitalization 6/19/2007 82 Female 10/21/2011 Physician United States
Primary
Secondary
Concomitant
Cough 1/1/2008 81 Female 10/24/2011 Consumer United States
Primary
Concomitant
Periodontal Infection Other Serious 9/19/2004 64 Female 11/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Female 11/27/2011 Consumer United States
Primary
Concomitant
Interacting
Hypotension Death 84 Male 12/8/2011 Lawyer United States
Primary
Concomitant
Dry Skin Hospitalization 9/27/2011 62 Female 12/19/2011 Physician Japan
Primary
Secondary
Decreased Appetite Hospitalization 10/1/2010 79 Female 108 lb 12/20/2011 Physician United States
Primary
Concomitant
Completed Suicide Death 1/1/2010 77 Female 12/22/2011 Physician United States
Primary
Secondary
Completed Suicide Death 77 Female 1/3/2012 Physician United States
Primary
Secondary
Tinnitus Hospitalization 1/1/2003 56 Female 155 lb 1/5/2012 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 77 Female 1/6/2012 Physician United States
Primary
Secondary
Pancreatitis Acute Other Serious 12/1/2008 49 191 lb 11/17/2011 Lawyer United States
Primary
Concomitant
Completed Suicide Death 77 Female 1/12/2012 Physician United States
Primary
Secondary
Pain In Jaw Other Serious 1/1/2003 56 Female 155 lb 1/14/2012 Consumer United States
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2010 77 Female 1/10/2012 Physician United States
Primary
Secondary
Completed Suicide Death 77 Female 1/13/2012 United States
Primary
Secondary
Completed Suicide Death 77 Female 1/17/2012 Other Health Professional Denmark
Primary
Secondary
Cryptococcosis Hospitalization 8/20/2011 72 Female 90 lb 1/27/2012 Consumer Japan
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2010 77 Female 1/21/2012 Physician United States
Primary
Secondary
Disseminated Intravascular Coagulation Death 8/20/2011 72 Female 90 lb 2/2/2012 Physician Japan
Primary
Secondary
Concomitant
Hand Fracture Other Serious 1/1/2003 56 Female 155 lb 2/8/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Completed Suicide Death 77 Female 2/8/2012 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2010 77 Female 3/2/2012 Physician United States
Primary
Secondary
Death Death 6/22/2011 65 Female 111 lb 3/23/2012 Physician United States
Primary
Concomitant
Cryptococcosis Hospitalization 8/20/2011 72 Female 90 lb 3/27/2012 Physician Japan
Primary
Secondary
Concomitant
Completed Suicide Death 77 Female 4/4/2012 Other Health Professional United States
Primary
Secondary
Dyspnoea Hospitalization 7/30/2009 72 Female 224 lb 5/28/2010 Physician United States
Primary
Concomitant
Chemical Burn Of Skin Other Serious 3/30/2012 57 Female 137 lb 4/15/2012 Consumer United States
Primary
Concomitant
Abnormal Dreams Other Serious 4/9/2012 62 Female 270 lb 4/12/2012 Pharmacist United States
Primary
Concomitant
Stomatitis Hospitalization 9/1/2009 77 Female 4/19/2012 Consumer United States
Primary
Concomitant
Osteonecrosis Other Serious 6/1/2006 52 Female 300 lb 4/24/2012 Physician United States
Primary
Secondary
Concomitant
Bladder Disorder Other Serious 6/1/2011 61 Male 300 lb 4/27/2012 Consumer United States
Primary
Secondary
Concomitant
Completed Suicide Death 77 Female 4/27/2012 Other Health Professional United States
Primary
Secondary
Peptic Ulcer Other Serious Female 4/30/2012 Consumer United States
Primary
Concomitant

Drug Data