Alendronate Sodium combined with Allopurinol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Po2 Decreased Other Serious 11/24/2005 54 Male 149 lb 1/25/2006 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 4/20/2004 53 Female 95 lb 1/31/2006 Physician Japan
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2005 48 Female 82 lb 2/8/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonitis Other Serious 11/24/2005 54 Male 149 lb 2/10/2006 Physician Japan
Primary
Concomitant
Nausea Other Serious 11/24/2005 54 Male 149 lb 2/16/2006 Physician Japan
Primary
Concomitant
Nausea Other Serious 11/24/2005 54 Male 149 lb 2/22/2006 Physician Japan
Primary
Concomitant
Ventricular Hypertrophy Other Serious 7/3/2005 Female 195 lb 3/3/2006 Physician United States
Primary
Concomitant
Renal Failure Other Serious 3/2/2006 39 Female 4/5/2006 Spain
Primary
Secondary
Concomitant
Urinary Tract Infection Required Intervention 3/16/2006 74 Male 5/9/2006 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 5/3/2005 49 Male 216 lb 5/17/2006 Physician United States
Primary
Secondary
Concomitant
Constipation Required Intervention 8/1/2006 80 Male 175 lb 8/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 4/17/2006 55 Male 261 lb 5/10/2006 Pharmacist United States
Primary
Concomitant
Retroperitoneal Haemorrhage Other Serious 9/17/2004 74 Female 141 lb 8/28/2006 Australia
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 3/16/2006 Male 9/15/2006 Physician Germany
Primary
Concomitant
Pneumonia Other Serious 2/27/2006 62 Female 101 lb 10/6/2006 Japan
Primary
Concomitant
Pulmonary Infarction Life Threatening 1/18/2007 61 Female 3/1/2007 Physician Japan
Primary
Concomitant
Henoch-schonlein Purpura Hospitalization 11/8/2006 Female 134 lb 4/26/2007 Physician Japan
Primary
Concomitant
Henoch-schonlein Purpura Hospitalization 11/8/2006 Female 134 lb 5/7/2007 Physician Japan
Primary
Concomitant
Rectal Haemorrhage Life Threatening 3/14/2007 79 Male 5/8/2007 Pharmacist United States
Primary
Concomitant
Pulmonary Infarction Life Threatening 1/18/2007 61 Female 5/17/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Tubular Disorder Other Serious 23 Male 5/18/2007 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Life Threatening 1/18/2007 61 Female 6/1/2007 Physician Japan
Primary
Secondary
Concomitant
Intestinal Haemorrhage Hospitalization 5/3/2007 70 Female 115 lb 5/31/2007 Consumer Brazil
Primary
Concomitant
Syncope Other Serious 5/14/2007 76 Female 6/15/2007 Canada
Primary
Concomitant
Henoch-schonlein Purpura Hospitalization 11/8/2006 Female 134 lb 7/25/2007 Physician Japan
Primary
Concomitant
Diabetes Mellitus Hospitalization 2/20/2007 Female 7/25/2007 Physician Japan
Primary
Concomitant
Renal Pain Other Serious 6/15/2004 Male 185 lb 7/25/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Rib Fracture Hospitalization 7/18/2007 76 Female 238 lb 8/31/2007 Consumer United Kingdom
Primary
Concomitant
Vascular Calcification Hospitalization 9/26/2006 9/6/2007 Consumer France
Primary
Secondary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 9/6/2007 Consumer United Kingdom
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 9/18/2007 Physician United Kingdom
Primary
Concomitant
Nausea Hospitalization 11/7/2006 61 Female 132 lb 9/17/2007 Austria
Primary
Concomitant
Delirium Hospitalization 7/28/2007 62 Male 141 lb 9/27/2007 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 12/18/2006 61 Female 110 lb 10/4/2007 Physician Japan
Primary
Secondary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 10/12/2007 Physician United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 7/17/2007 68 110 lb 10/23/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/28/2007 62 Male 141 lb 11/2/2007 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 7/17/2007 68 110 lb 11/8/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/28/2007 62 Male 141 lb 11/9/2007 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 7/17/2007 68 Unknown 110 lb 11/19/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/28/2007 62 Male 141 lb 11/26/2007 Physician Japan
Primary
Secondary
Concomitant
Injection Site Swelling 9/1/2006 Female 12/14/2007 United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 2/20/2007 Female 12/19/2007 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 11/23/2007 Female 68 lb 2/1/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/15/2008 Consumer United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/22/2008 United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/27/2008 United Kingdom
Primary
Secondary
Thrombocytopenia Life Threatening 11/28/2007 Female 68 lb 2/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Toxic Skin Eruption 1/2/2008 72 Male 3/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 3/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Pyrexia Hospitalization 7/28/2007 62 Male 141 lb 3/5/2008 Physician Japan
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 3/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Platelet Count Decreased Other Serious 8/21/2007 46 Female 121 lb 3/20/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/21/2007 63 Female 4/2/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Life Threatening 1/16/2008 Female 4/24/2008 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Death 1/1/1990 Female 103 lb 5/8/2008 United States
Primary
Concomitant
Renal Failure Death 1/1/1990 Female 103 lb 5/15/2008 United States
Primary
Concomitant
Thrombin-antithrombin Iii Complex Abnormal Other Serious 12/18/2006 61 Female 110 lb 5/9/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/30/2007 60 Male 234 lb 5/16/2008 Physician Japan
Primary
Concomitant
Persecutory Delusion Hospitalization 2/24/2008 62 Male 5/28/2008 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Death 1/1/1990 Female 103 lb 5/30/2008 United States
Primary
Concomitant
Renal Failure Death 1/1/1990 Female 103 lb 7/15/2008 United States
Primary
Concomitant
Respiratory Failure Other Serious 12/18/2006 61 Female 110 lb 7/18/2008 Physician Japan
Primary
Secondary
Concomitant
Skin Oedema Hospitalization 77 Female 7/31/2008 Other Health Professional France
Primary
Secondary
Concomitant
Tongue Coated Hospitalization 3/16/2006 Male 8/7/2008 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 7/8/2008 71 Male 8/15/2008 Other Health Professional United States
Primary
Concomitant
Pruritus 5/1/2008 Female 222 lb 8/29/2008 Consumer United States
Primary
Concomitant
Electrocardiogram T Wave Inversion Other Serious 2/11/2008 Male 9/30/2008 Other Health Professional Australia
Primary
Concomitant
Gastrointestinal Haemorrhage Death 9/28/2008 Male 10/3/2008 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 12/18/2006 61 Female 11/18/2008 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 9/28/2008 Male 1/6/2009 Physician United States
Primary
Concomitant
Hypotension Other Serious 12/16/2008 70 Female 1/20/2009 Physician United Kingdom
Primary
Concomitant
Hypotension Other Serious 12/16/2008 70 Female 1/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 10/17/2008 Male 254 lb 1/16/2009 Pharmacist United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 9/28/2008 Male 1/28/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 73 Male 287 lb 5/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 72 Male 6/30/2009 Lawyer United States
Primary
Concomitant
Renal Impairment Other Serious 4/1/2009 75 7/15/2009 Pharmacist Japan
Primary
Concomitant
Renal Impairment Other Serious 4/1/2009 75 7/21/2009 Japan
Primary
Concomitant
Rectal Haemorrhage Other Serious 4/1/2009 72 Male 155 lb 7/16/2009
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 7/31/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Cell Carcinoma Life Threatening 5/5/2009 Male 214 lb 8/10/2009 Other Health Professional New Zealand
Primary
Concomitant
Weight Decreased Hospitalization 4/26/2008 85 Female 8/3/2009 Lawyer United States
Primary
Concomitant
Thrombosis Hospitalization 7/20/2009 87 Male 8/7/2009 United Kingdom
Primary
Concomitant
Melaena Hospitalization 7/20/2009 87 Male 8/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/26/2008 85 Female 8/10/2009 Lawyer United States
Primary
Concomitant
Melaena Hospitalization 7/20/2009 87 Male 8/13/2009 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/26/2008 85 Female 8/26/2009 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 7/20/2009 87 Male 8/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 79 Female 9/8/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 79 Female 9/8/2009 United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 72 Male 9/18/2009 Consumer United Kingdom
Primary
Secondary
Ventricular Hypokinesia Life Threatening 7/30/2009 48 Male 157 lb 9/18/2009 Physician Japan
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 9/8/2009 66 Female 229 lb 10/1/2009 Pharmacist United States
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 7/30/2009 48 Male 157 lb 10/6/2009 Physician Japan
Primary
Concomitant
Pulmonary Hypertension Death 9/23/2009 Female 10/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 79 Female 11/18/2009 United States
Primary
Concomitant
Pulmonary Hypertension Death 9/23/2009 Female 12/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 4/26/2008 85 Female 12/1/2009 United States
Primary
Concomitant
Shock Death 7/8/2009 53 Male 127 lb 12/29/2009 Pharmacist United States
Primary
Concomitant
Malignant Neoplasm Progression Death 7/25/2009 Female 1/21/2010 Pharmacist United States
Primary
Concomitant
Pulmonary Congestion Other Serious 2/1/2009 48 Male 139 lb 1/20/2010 Physician Japan
Primary
Concomitant
Septic Shock Hospitalization 12/9/2008 Male 2/12/2010 Physician Japan
Primary
Secondary
Concomitant
Disease Progression Death 9/28/2009 74 Male 3/6/2010 Pharmacist United States
Primary
Concomitant
Road Traffic Accident Other Serious 12/1/2009 68 Male 165 lb 3/16/2010 Consumer United States
Primary
Concomitant
Septic Shock Hospitalization 12/9/2008 Male 132 lb 3/23/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 11/6/2006 Male 246 lb 3/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 11/6/2006 69 Male 246 lb 4/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nodule Other Serious 3/1/2010 74 Male 4/27/2010 Consumer United States
Primary
Concomitant
Erythema Multiforme Hospitalization 4/7/2010 64 Female 86 lb 5/28/2010 Physician Japan
Primary
Secondary
Gastrointestinal Haemorrhage Death Male 128 lb 6/22/2010 Physician Canada
Primary
Concomitant
Pancytopenia Life Threatening 5/9/2010 82 Male 6/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/21/2007 63 Female 93 lb 6/28/2010 Physician Japan
Primary
Secondary
Concomitant
Erythema Multiforme Hospitalization 4/7/2010 64 Female 86 lb 7/8/2010 Physician Japan
Primary
Secondary
Weight Increased 1/1/2007 54 Female 7/16/2010 Other Health Professional United States
Primary
Interacting
Renal Failure Chronic Other Serious 7/1/2010 79 Male 7/26/2010 Consumer United States
Primary
Concomitant
Thyroid Cancer Other Serious 2/27/2010 56 Female 252 lb 7/28/2010 Consumer United States
Primary
Concomitant
Pain 12/1/2008 76 Male 165 lb 8/3/2010 Physician United States
Primary
Concomitant
Renal Failure Chronic Other Serious 5/7/2010 79 Male 220 lb 8/6/2010 Consumer United States
Primary
Concomitant
Thyroid Cancer Other Serious 2/27/2010 56 Female 252 lb 8/11/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Other Serious 5/7/2010 79 Male 220 lb 8/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 5/7/2010 79 Male 220 lb 8/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Whiplash Injury Other Serious 2/15/1997 47 Female 119 lb 9/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Whiplash Injury Other Serious 2/15/1997 47 Female 119 lb 12/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Whiplash Injury Other Serious 2/15/1997 47 Female 119 lb 12/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Macular Degeneration Other Serious 12/1/2010 82 Female 12/13/2010 Consumer United States
Primary
Concomitant
Azotaemia Hospitalization 2/15/1997 47 Female 119 lb 1/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Stress Urinary Incontinence Hospitalization 4/26/2008 85 Female 100 lb 1/13/2011 Lawyer United States
Primary
Concomitant
Herpes Zoster Hospitalization 3/21/2007 63 Female 93 lb 1/21/2011 Physician Japan
Primary
Secondary
Concomitant
Macular Degeneration Other Serious 12/1/2010 82 Female 3/1/2011 Consumer United States
Primary
Concomitant
Rash Erythematous 7/16/2009 79 Female 130 lb 3/17/2011 United States
Primary
Secondary
Concomitant
Renal Osteodystrophy Hospitalization 2/15/1997 47 Female 119 lb 3/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Required Intervention 3/30/2011 80 Female 3/30/2011 Pharmacist United States
Primary
Concomitant
Osteonecrosis Other Serious 12/22/2010 33 Female 4/15/2011 Other Health Professional India
Primary
Secondary
Concomitant
Respiratory Failure Death 12/9/2010 75 Male 130 lb 4/27/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 12/22/2010 33 Female 5/3/2011 Other Health Professional India
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/30/2010 82 Female 5/12/2011 Physician United States
Primary
Concomitant
Oral Disorder Disability 2/15/1997 47 Female 119 lb 5/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 4/20/2011 75 Female 6/1/2011 Other Health Professional United Kingdom
Primary
Concomitant
Seronegative Arthritis Other Serious 72 Male 6/1/2011 Other Health Professional New Zealand
Primary
Concomitant
Orthostatic Hypotension Hospitalization 4/5/2011 80 Male 6/30/2011 Physician Sweden
Primary
Secondary
Concomitant
Bile Duct Stone Death 12/26/2008 75 Male 139 lb 7/12/2011 Physician Japan
Primary
Concomitant
Pancytopenia Hospitalization 4/5/2011 79 Female 7/12/2011 Physician Japan
Primary
Secondary
Lactic Acidosis Death 3/31/2011 75 Female 7/20/2011 Physician Italy
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 3/31/2011 75 Female 7/21/2011 Consumer Italy
Primary
Concomitant
Hyperamylasaemia Hospitalization 12/6/2008 32 Female 90 lb 7/21/2011 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Death 1/1/2011 67 Female 7/21/2011 Other Health Professional Italy
Primary
Concomitant
Pneumonia Hospitalization 4/5/2011 79 Female 8/1/2011 Physician Japan
Primary
Secondary
Multi-organ Failure Hospitalization 4/5/2011 79 Male 8/5/2011 Other Health Professional Japan
Primary
Secondary

Drug Data