Alendronate Sodium combined with Alfacalcidol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rash Hospitalization 11/7/2005 Female 1/11/2006 Physician Japan
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 1/1/2005 Female 1/26/2006 Hungary
Primary
Concomitant
Cholestasis Hospitalization 3/14/2006 Female 7/10/2006 Pharmacist Japan
Primary
Concomitant
Syncope Hospitalization 1/1/2006 Male 154 lb 11/16/2006 Physician United Kingdom
Primary
Concomitant
Soft Tissue Inflammation Hospitalization 9/22/2005 Female 157 lb 11/30/2006 Greece
Primary
Concomitant
Soft Tissue Inflammation Hospitalization 9/22/2005 Female 157 lb 12/13/2006 Greece
Primary
Concomitant
Pneumonia Other Serious 2/27/2006 62 Female 101 lb 12/6/2006 Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 74 Female 2/16/2007 Pharmacist Japan
Primary
Concomitant
Sepsis Hospitalization 12/19/2006 Female 141 lb 4/5/2007 Belgium
Primary
Concomitant
Thrombocytopenia Hospitalization 12/19/2006 Female 141 lb 4/18/2007 Belgium
Primary
Concomitant
Nausea Hospitalization 6/21/2007 59 Female 7/19/2007 Pharmacist Japan
Primary
Concomitant
Insulin Autoimmune Syndrome Other Serious 83 Male 12/17/2007 Pharmacist Japan
Primary
Concomitant
Insulin Autoimmune Syndrome Other Serious 83 Male 1/25/2008 Pharmacist Japan
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 1/25/2007 Female 97 lb 1/30/2008 Japan
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 4/23/2008 81 Female 6/20/2008 Pharmacist Japan
Primary
Concomitant
Interacting
Prothrombin Time Prolonged 4/23/2008 Female 8/27/2008 Pharmacist Japan
Primary
Concomitant
Interacting
Pain In Extremity Hospitalization 8/4/2008 60 Female 117 lb 10/14/2008 Consumer Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/19/2006 Female 141 lb 12/18/2008 Belgium
Primary
Concomitant
Pleurisy Hospitalization 11/25/2008 Male 1/2/2009 Japan
Primary
Concomitant
Drug Eruption Hospitalization 11/30/2008 Female 1/16/2009 Physician Japan
Primary
Secondary
Concomitant
Drug Eruption Hospitalization 11/30/2008 Female 1/27/2009 Physician Japan
Primary
Secondary
Concomitant
Pleurisy Hospitalization 11/25/2008 Male 1/27/2009 Japan
Primary
Concomitant
Enterocolitis Bacterial Hospitalization 12/9/2008 Female 79 lb 1/28/2009 Japan
Primary
Concomitant
Pleurisy Hospitalization 11/25/2008 Male 2/9/2009 Japan
Primary
Concomitant
Drug Eruption Hospitalization 11/30/2008 Female 2/10/2009 Physician Japan
Primary
Secondary
Concomitant
Paralysis Hospitalization 12/12/2008 Female 140 lb 2/12/2009 Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/25/2008 Male 2/19/2009 Japan
Primary
Concomitant
Pyrexia Hospitalization 11/25/2008 Male 3/5/2009 Japan
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 2/9/2009 76 Female 4/1/2009 Other Health Professional Japan
Primary
Concomitant
Pyrexia Hospitalization 11/25/2008 Male 4/7/2009 Japan
Primary
Concomitant
Peritonitis Death 1/1/2009 Female 93 lb 5/13/2009 Physician Japan
Primary
Concomitant
Peritonitis Death 1/1/2009 Female 93 lb 5/14/2009 Physician Japan
Primary
Concomitant
Foot Deformity Hospitalization 3/10/2009 Female 126 lb 5/19/2009 Japan
Primary
Concomitant
Enterocolitis Bacterial Hospitalization 12/3/2008 Female 79 lb 6/3/2009 Japan
Primary
Concomitant
Paralysis Hospitalization 12/12/2008 Female 140 lb 6/9/2009 Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/30/2009 Female 132 lb 6/19/2009 Japan
Primary
Concomitant
Septic Shock Death 4/11/2009 Female 93 lb 6/26/2009 Physician Japan
Primary
Concomitant
Foot Deformity Hospitalization 3/10/2009 Female 126 lb 7/8/2009 Japan
Primary
Concomitant
Pyrexia Hospitalization 9/22/2008 Female 94 lb 7/8/2009 Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 1/30/2009 Female 132 lb 7/14/2009 Japan
Primary
Secondary
Concomitant
Enterocolitis Bacterial Hospitalization 12/3/2008 Female 79 lb 7/30/2009 Japan
Primary
Concomitant
Enterocolitis Bacterial Hospitalization 12/3/2008 Female 79 lb 8/4/2009 Japan
Primary
Concomitant
Pneumonia Hospitalization 3/28/2009 Female 119 lb 8/7/2009 Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 1/30/2009 Female 110 lb 8/21/2009 Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/22/2008 Female 94 lb 8/21/2009 Japan
Primary
Concomitant
Pneumonia Hospitalization 3/28/2009 Female 119 lb 8/21/2009 Japan
Primary
Concomitant
Visual Acuity Reduced Disability 6/26/2009 Female 90 lb 8/21/2009 Japan
Primary
Secondary
Concomitant
Visual Impairment Other Serious 6/26/2009 Female 90 lb 8/26/2009 Japan
Primary
Secondary
Concomitant
Tuberculous Pleurisy Hospitalization 1/20/2009 Female 126 lb 9/4/2009 Japan
Primary
Concomitant
Visual Impairment Other Serious 6/26/2009 Female 90 lb 9/11/2009 Japan
Primary
Secondary
Concomitant
Paralysis Hospitalization 12/12/2008 Female 140 lb 9/25/2009 Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 5/25/2009 Female 82 lb 9/30/2009 Japan
Primary
Concomitant
Pneumonia Hospitalization 3/28/2009 Female 119 lb 10/7/2009 Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 1/30/2009 Female 110 lb 10/8/2009 Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 9/15/2009 Female 128 lb 11/16/2009 Physician Japan
Primary
Secondary
Concomitant
Paralysis Hospitalization 12/12/2008 Female 140 lb 12/4/2009 Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 5/25/2009 Female 82 lb 12/4/2009 Japan
Primary
Concomitant
Herpes Virus Infection Hospitalization 1/25/2007 57 Female 97 lb 12/11/2009 Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 9/29/2009 Female 128 lb 1/5/2010 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 9/29/2009 Female 128 lb 1/13/2010 Physician Japan
Primary
Secondary
Concomitant
Intestinal Adenocarcinoma Other Serious 11/26/2009 59 Female 178 lb 1/21/2010 Physician Canada
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/5/2009 Female 1/22/2010 Japan
Primary
Concomitant
Intestinal Adenocarcinoma Other Serious 11/26/2009 59 Female 178 lb 1/25/2010 Physician Canada
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 6/22/2009 Male 117 lb 2/1/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/7/2009 Female 2/19/2010 Japan
Primary
Concomitant
Synovial Rupture Hospitalization 12/16/2009 Female 2/25/2010 Japan
Primary
Secondary
Concomitant
Synovial Rupture Hospitalization 12/16/2009 Female 3/2/2010 Japan
Primary
Secondary
Concomitant
Gastrointestinal Surgery Hospitalization 3/11/2010 Female 108 lb 3/22/2010 Physician Japan
Primary
Concomitant
Sick Sinus Syndrome Other Serious 2/1/2010 Male 126 lb 3/25/2010 Japan
Primary
Secondary
Concomitant
Sick Sinus Syndrome Other Serious 2/1/2010 61 Male 126 lb 4/5/2010 Japan
Primary
Secondary
Concomitant
Pneumonia Primary Atypical Hospitalization 3/1/2010 65 Female 3/30/2010 Other Health Professional Japan
Primary
Concomitant
Pneumonia Pneumococcal Hospitalization 3/17/2010 65 Female 4/7/2010 Japan
Primary
Secondary
Concomitant
Sick Sinus Syndrome Other Serious 2/1/2010 61 Male 126 lb 4/15/2010 Japan
Primary
Secondary
Concomitant
Urticaria Hospitalization 3/17/2010 65 Female 4/19/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Urticaria Hospitalization 3/17/2010 65 Female 4/27/2010 Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 8/7/2009 71 Female 89 lb 5/24/2010 Japan
Primary
Concomitant
Urticaria Hospitalization 3/17/2010 65 Female 5/21/2010 Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/30/2009 72 Female 95 lb 6/14/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/30/2009 72 Female 95 lb 6/15/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/30/2009 72 Female 95 lb 6/18/2010 Physician Japan
Primary
Secondary
Concomitant
Meningitis Other Serious 4/7/2010 44 Female 6/23/2010 Physician Japan
Primary
Concomitant
Tuberculosis Hospitalization 2/17/2010 68 Male 119 lb 6/28/2010 Physician Japan
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 2/17/2010 68 Male 119 lb 6/30/2010 Physician Japan
Primary
Secondary
Concomitant
Cough Hospitalization 12/29/2009 60 Female 122 lb 7/2/2010 Physician Japan
Primary
Secondary
Concomitant
Wound Infection Other Serious 11/26/2009 59 Female 178 lb 7/6/2010 Physician Canada
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 6/22/2009 66 Male 117 lb 7/6/2010 Physician Japan
Primary
Secondary
Concomitant
Wound Infection Other Serious 11/26/2009 59 Female 178 lb 7/8/2010 Physician Canada
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Other Serious 4/1/2004 63 Male 7/29/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 8/7/2009 71 Female 89 lb 8/4/2010 Physician Japan
Primary
Concomitant
Cough Hospitalization 12/29/2009 60 Female 122 lb 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 2/17/2010 68 Male 119 lb 8/18/2010 Physician Japan
Primary
Secondary
Concomitant
Kyphosis Hospitalization 12/29/2009 60 Female 122 lb 8/27/2010 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 7/1/2010 70 Female 9/3/2010 Physician Japan
Primary
Concomitant
Paralysis Hospitalization 12/12/2008 68 Female 140 lb 9/14/2010 Physician Japan
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 2/17/2010 68 Male 119 lb 9/14/2010 Physician Japan
Primary
Secondary
Concomitant
Femur Fracture Hospitalization 9/8/2010 79 Female 122 lb 9/20/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/15/2009 56 Female 86 lb 9/27/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 9/8/2010 79 Female 122 lb 10/18/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 12/17/2009 73 Female 117 lb 11/15/2010 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 8/7/2009 71 Female 89 lb 11/22/2010 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 2/19/2009 11/23/2010 Other Health Professional Japan
Primary
Concomitant
Renal Failure Acute Other Serious 8/7/2009 71 Female 89 lb 12/2/2010 Physician Japan
Primary
Concomitant
Occult Blood Positive Hospitalization 10/21/2010 56 Female 11/17/2010 Other Health Professional Japan
Primary
Concomitant
Viith Nerve Paralysis Hospitalization 10/23/2010 12/8/2010 Physician Japan
Primary
Concomitant
Sick Sinus Syndrome Other Serious 2/1/2010 61 Male 126 lb 12/13/2010 Physician Japan
Primary
Secondary
Concomitant
Viith Nerve Paralysis Hospitalization 10/23/2010 12/13/2010 Physician Japan
Primary
Concomitant
Vision Blurred Hospitalization 10/23/2010 12/23/2010 Physician Japan
Primary
Concomitant
Colon Adenoma Hospitalization 10/21/2010 56 Female 12/16/2010 Other Health Professional Japan
Primary
Concomitant
Subcutaneous Abscess Hospitalization 12/16/2009 56 Female 12/15/2010 Japan
Primary
Secondary
Concomitant
Computerised Tomogram Abnormal Hospitalization 2/17/2010 68 Male 119 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 12/7/2010 62 Female 12/29/2010 Other Health Professional Japan
Primary
Concomitant
Joint Stiffness Hospitalization 2/17/2010 68 Male 119 lb 1/14/2011 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 10/23/2010 63 Female 108 lb 2/7/2011 Other Health Professional Japan
Primary
Concomitant
Arthralgia Hospitalization 2/17/2010 68 Male 119 lb 2/18/2011 Physician Japan
Primary
Secondary
Concomitant
Chest X-ray Abnormal Hospitalization 2/17/2010 68 Male 119 lb 2/23/2011 Physician Japan
Primary
Secondary
Concomitant
Femur Fracture Hospitalization 9/8/2010 79 Female 123 lb 3/25/2011 Consumer United States
Primary
Concomitant
Joint Stiffness Hospitalization 2/17/2010 68 Male 119 lb 3/25/2011 Physician Japan
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 12/17/2009 73 Female 117 lb 4/5/2011 Physician Japan
Primary
Concomitant
Arthralgia Hospitalization 11/29/2010 86 Female 75 lb 4/5/2011 Physician Japan
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 7/23/2008 36 Female 139 lb 4/7/2011 Physician Japan
Primary
Concomitant
Spinal Compression Fracture Other Serious 2/3/2010 74 Female 5/11/2011 Japan
Primary
Concomitant
Pneumonia Hospitalization 9/27/2009 74 Female 94 lb 5/23/2011 Physician Japan
Primary
Secondary
Concomitant
Dizziness Other Serious 9/27/2009 74 Female 94 lb 5/24/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Arterial Hypertension Hospitalization 2/24/2007 28 Female 5/26/2011 Physician Japan
Primary
Concomitant
Patella Fracture Hospitalization 12/16/2009 64 Female 82 lb 6/3/2011 Physician Japan
Primary
Concomitant
Rheumatoid Factor Increased Hospitalization 9/27/2009 74 Female 94 lb 6/8/2011 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Other Serious 2/3/2010 74 Female 6/9/2011 Physician Japan
Primary
Concomitant
Spinal Compression Fracture Hospitalization 2/3/2010 74 Female 6/17/2011 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 2/19/2009 61 Female 134 lb 6/17/2011 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 2/3/2010 74 Female 6/30/2011 Physician Japan
Primary
Concomitant
Haematuria Hospitalization 4/1/2004 63 Male 7/28/2011 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Hospitalization 2/3/2010 74 Female 8/2/2011 Physician Japan
Primary
Concomitant
Hallucination Other Serious 8/1/2011 75 Female 8/12/2011 Pharmacist Japan
Primary
Concomitant
Cardiac Disorder Death 2/3/2010 74 Female 8/17/2011 Physician Japan
Primary
Concomitant
Alanine Aminotransferase Increased Death 12/28/2010 83 Female 99 lb 8/26/2011 Physician Japan
Primary
Concomitant
Chills Hospitalization 2/15/2007 28 Female 9/6/2011 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/7/2011 Male 99 lb 9/8/2011 Physician Japan
Primary
Concomitant
Back Pain Hospitalization 2/17/2010 68 Male 119 lb 9/15/2011 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 4/1/2004 63 Male 9/20/2011 Physician Namibia
Primary
Secondary
Concomitant
Decubitus Ulcer Other Serious 12/16/2009 64 Female 82 lb 9/21/2011 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 12/16/2009 64 Female 82 lb 10/18/2011 Japan
Primary
Concomitant
Arthralgia Hospitalization 1/20/2009 65 Female 126 lb 10/19/2011 Physician Japan
Primary
Concomitant
Hyperkalaemia Other Serious 2/1/2010 61 Male 126 lb 10/21/2011 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 12/28/2010 83 Female 99 lb 10/21/2011 Physician Japan
Primary
Concomitant
Pneumothorax Other Serious 2/1/2010 61 Male 126 lb 11/2/2011 Physician Japan
Primary
Secondary
Concomitant
Dermal Cyst Hospitalization 4/1/2004 63 Male 11/30/2011 Japan
Primary
Secondary
Concomitant
Antibody Test Abnormal Other Serious 7/20/2011 82 Female 123 lb 12/14/2011 Physician Japan
Primary
Concomitant
Pulmonary Embolism Death 8/31/2010 54 Female 117 lb 12/14/2011 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 2/7/2011 Male 99 lb 12/28/2011 Physician Japan
Primary
Concomitant
Dehydration Life Threatening Male 154 lb 1/13/2012 Pharmacist Ireland
Primary
Concomitant

Drug Data