Alendronate combined with Omeprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rectal Polyp Other Serious 5/15/2005 Male 181 lb 4/24/2009 United Kingdom
Primary
Concomitant
Product Substitution Issue Hospitalization 3/14/2009 Female 160 lb 4/21/2009 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Death 12/18/2008 79 Male 4/12/2009 Germany
Primary
Secondary
Concomitant
Chest Pain Hospitalization 68 Male 6/4/2009 Physician United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 10/28/2008 70 Male 183 lb 6/4/2009 Physician Israel
Primary
Concomitant
Malabsorption Female 6/22/2009 Consumer United States
Primary
Concomitant
Osteomyelitis Hospitalization 3/18/2008 62 Female 6/29/2009
Primary
Concomitant
Vomiting 11/5/2009 61 Female 200 lb 11/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting 11/5/2009 61 Female 200 lb 11/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 3/27/2009 Female 150 lb 11/17/2009 Brazil
Primary
Concomitant
Thirst 67 Female 161 lb 5/3/2010 United States
Primary
Concomitant
Drug Ineffective 3/28/2010 58 Female 175 lb 5/11/2010 Consumer United States
Primary
Concomitant
Renal Failure Life Threatening 3/11/2010 77 Female 170 lb 5/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2008 24 Female 5/25/2010 Pharmacist Canada
Primary
Concomitant
Renal Failure Life Threatening 3/11/2010 77 Female 170 lb 5/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nodule Other Serious 3/1/2010 74 Male 174 lb 5/27/2010 Physician United States
Primary
Concomitant
Vomiting 4/27/2010 65 Female 168 lb 6/1/2010 Consumer United States
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Life Threatening 5/28/2010 93 Female 179 lb 5/29/2010 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/1/2009 63 Male 6/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Other Serious 5/20/2010 63 Female 7/6/2010 Physician Czech Republic
Primary
Concomitant
Pneumonia Hospitalization 6/1/2010 67 Female 7/9/2010 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 5/20/2010 63 Female 7/13/2010 Physician Czech Republic
Primary
Concomitant
Visual Impairment Other Serious 1/1/2007 60 Female 139 lb 12/3/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 1/1/2007 60 Female 139 lb 12/3/2010 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 2/18/2008 68 Male 12/7/2010 Physician Canada
Primary
Concomitant
Cough 71 Female 180 lb 12/6/2010 United States
Primary
Concomitant
Prostatic Specific Antigen Increased 12/10/2010 77 Male 1/6/2011 Consumer
Primary
Concomitant
Infection Hospitalization 12/1/2010 77 Male 1/7/2011 Consumer Canada
Primary
Concomitant
Pneumonia Hospitalization Female 178 lb 1/12/2011 Physician United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 9/16/2010 54 Male 176 lb 2/4/2011 Physician United Kingdom
Primary
Concomitant
Prostatic Specific Antigen Increased 12/10/2010 77 Male 2/4/2011 Consumer
Primary
Concomitant
Weight Decreased Other Serious 10/24/2010 57 Male 150 lb 2/1/2011 Pharmacist United States
Primary
Concomitant
Tendon Rupture Disability 1/26/2011 78 Male 175 lb 2/9/2011 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Death Female 124 lb 2/15/2011 Other Health Professional United States
Primary
Concomitant
Depressed Level Of Consciousness 12/28/2010 81 Female 2/11/2011 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Hospitalization 12/3/2010 62 Female 80 lb 2/17/2011 Physician United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/1/2010 54 Female 2/22/2011 Physician United States
Primary
Concomitant
Hypovolaemic Shock Hospitalization 1/14/2010 72 Female 166 lb 4/1/2011 Physician United States
Primary
Secondary
Concomitant
Flank Pain Hospitalization 3/28/2011 62 Male 185 lb 4/5/2011 Physician United States
Primary
Secondary
Concomitant
Drug Administration Error Other Serious 76 Female 4/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Jaundice Cholestatic Hospitalization 4/2/2012 80 Male 165 lb 6/7/2012 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 1/14/2010 72 Female 166 lb 7/3/2013 Physician Us
Primary
Secondary
Concomitant
Synovitis Death 9/27/2010 74 Female 113 lb 8/2/2013 Other Health Professional Us
Primary
Concomitant
Tremor Other Serious 2003 Male 185 lb 10/12/2012 Lawyer Us
Primary
Concomitant
Suprapubic Pain Hospitalization 12/12/2010 74 Female 3/12/2013 Physician Country Not Specified
Primary
Concomitant
Prostate Cancer Other Serious 3/2012 74 Male 8/29/2012 Consumer Ca
Primary
Secondary
Concomitant
Pneumonia Other Serious Female 7/12/2013 Consumer Br
Primary
Concomitant
Rheumatoid Arthritis 4/2013 43 Female 7/26/2013 Us
Primary
Secondary
Concomitant
Pain In Extremity Other Serious Female 310 lb 10/15/2013 Us
Primary
Secondary
Concomitant
Rheumatoid Arthritis Death 70 Female 112 lb 9/7/2012 Other Health Professional Gb
Primary
Concomitant
Visual Acuity Reduced Hospitalization 2009 60 Female 130 lb 9/4/2012 Physician Br
Primary
Secondary
Concomitant
Weight Bearing Difficulty Hospitalization 2011 Female 12/11/2012 Other Health Professional Country Not Specified
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 4/5/2012 72 Male 128 lb 6/3/2013 Consumer Us
Primary
Concomitant
Stress Fracture Other Serious 1/2009 79 Female 7/12/2013 Us
Primary
Secondary
Concomitant
Syncope Hospitalization 8/13/2008 62 Female 194 lb 11/22/2013 Physician Br
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 68 Female 185 lb 9/7/2012 Physician Us
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/23/2012 59 Female 12/26/2012 Other Health Professional Ie
Primary
Concomitant
Hyperammonaemia Other Serious 64 Male 10/8/2012 Consumer Gb
Primary
Concomitant
Pulmonary Congestion Hospitalization 7/2012 65 Female 159 lb 10/29/2013 Consumer Us
Primary
Concomitant
Vitamin B12 Deficiency Hospitalization 80 Female 10/11/2012 Us
Primary
Secondary
Concomitant
Middle Insomnia Other Serious 26 Female 177 lb 10/18/2012 Other Health Professional Br
Primary
Concomitant
Rheumatoid Arthritis Other Serious Male 209 lb 10/19/2012 Consumer Ca
Primary
Concomitant
Multi-organ Failure Death 8/4/2012 77 Female 119 lb 11/15/2012 Other Health Professional Country Not Specified
Primary
Concomitant
Pyrexia Hospitalization 12/16/2011 59 Female 142 lb 10/22/2012 Pharmacist Br
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 10/10/2012 72 Female 150 lb 10/26/2012 Pharmacist Us
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 1/2010 Male 167 lb 12/11/2012 Physician Au
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 3/1/2012 37 Male 10/25/2012 Physician Gb
Primary
Concomitant
Menstruation Irregular 46 Female 10/25/2012 Physician Us
Primary
Concomitant
Pneumonia 1/23/2012 66 Male 60 lb 10/26/2012 Physician Us
Primary
Concomitant
Vomiting Life Threatening 4/28/2012 71 Female 4/22/2013 Consumer Us
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 12/13/2011 76 Male 176 lb 2/8/2013 Physician Gb
Primary
Concomitant
Thoracic Vertebral Fracture Death 9/2012 Female 162 lb 11/16/2012 Other Health Professional Country Not Specified
Primary
Concomitant
Weight Decreased Other Serious 83 Male 11/2/2012 Other Health Professional Nz
Primary
Concomitant
Urine Analysis Abnormal Other Serious 10/22/2012 58 Female 160 lb 12/13/2012 Other Health Professional Us
Primary
Concomitant
Stress Fracture Other Serious 10/5/2011 61 Female 11/1/2012 Physician Us
Primary
Secondary
Concomitant
Melaena Hospitalization 10/16/2012 62 Female 161 lb 11/16/2012 Other Health Professional Gb
Primary
Concomitant
Skin Fissures Hospitalization 1/27/2012 70 Female 139 lb 11/21/2012 Physician Gb
Primary
Secondary
Concomitant
Vomiting Life Threatening 4/28/2012 71 Female 11/28/2012 Consumer Us
Primary
Secondary
Concomitant
Diarrhoea Other Serious 69 Female 160 lb 12/6/2012 Consumer Us
Primary
Concomitant
Neutrophilia Hospitalization 83 Male 12/17/2012 Other Health Professional Country Not Specified
Primary
Secondary
Concomitant
Joint Destruction Hospitalization Male 174 lb 12/26/2012 Consumer Ca
Primary
Concomitant
Infusion Related Reaction Other Serious 8/30/2012 53 Female 143 lb 1/7/2013 Pharmacist Br
Primary
Concomitant
Wheelchair User Other Serious 6/2012 Female 3/1/2013 Physician Us
Primary
Concomitant
Medication Error Disability 12/2/2012 91 Female 117 lb 1/9/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Blister 12/2012 76 Female 133 lb 2/6/2013 Physician Us
Primary
Concomitant
Medication Error Hospitalization 12/2/2012 91 Female 117 lb 1/15/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Thrombosis Hospitalization 2012 Female 5/7/2013 Consumer Us
Primary
Concomitant
Sinusitis 1/14/2012 67 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Vitamin D Decreased 10/2011 40 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Foot Fracture Other Serious 12/15/2012 45 Female 165 lb 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Staphylococcal Infection 11/8/2012 68 Female 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Death Death Female 2/5/2013 Other Health Professional Ca
Primary
Concomitant
Femoral Neck Fracture Hospitalization 5/23/2012 Male 2/7/2013 Physician Gb
Primary
Concomitant
Joint Stiffness 3/2012 Female 113 lb 1/31/2013 Consumer Us
Primary
Concomitant
Skin Irritation 2/25/2012 40 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Injection Site Mass 5/24/2012 55 Male 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Pelvic Pain Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Sepsis Death 12/11/2012 86 Female 5/31/2013 Other Health Professional Gb
Primary
Concomitant
Hypoglycaemia Other Serious 12/2012 84 Male 1/31/2013 Other Health Professional Gb
Primary
Concomitant
Cerebrovascular Accident Disability 1/21/2013 81 Female 141 lb 2/23/2013 Physician Gb
Primary
Concomitant
Overdose Other Serious 1/2011 Female 2/25/2013 Consumer Us
Primary
Concomitant
Herpes Zoster 1/16/2013 55 Female 153 lb 3/5/2013 Other Health Professional Us
Primary
Concomitant
Foot Fracture Other Serious 1/29/2013 60 Female 205 lb 3/13/2013 Consumer Ca
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Hospitalization 2007 Female 161 lb 6/21/2013 Physician Us
Primary
Concomitant
Osteoporosis 2003 82 Female 121 lb 5/3/2013 Us
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 10/2012 Female 3/19/2013 Consumer Us
Primary
Concomitant
Malaise Hospitalization 2013 Female 125 lb 3/19/2013 Other Health Professional Us
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/19/2011 60 Female 136 lb 3/20/2013 Physician Mx
Primary
Concomitant
Pancreatitis Other Serious 2009 Male 196 lb 3/25/2013 Consumer Us
Primary
Concomitant
Diverticulum Hospitalization 10/18/2012 83 Female 161 lb 7/8/2013 Physician Gb
Primary
Concomitant
Rash Pruritic Other Serious 8/2012 80 Female 9/14/2012 Physician Us
Primary
Concomitant
Renal Failure Acute Hospitalization 4/23/2013 83 Female 136 lb 4/25/2013 Other Health Professional Us
Primary
Concomitant
Renal Failure Acute Hospitalization 4/24/2013 Female 9/23/2013 Physician Us
Primary
Secondary
Concomitant
Pruritus Hospitalization 12/2012 67 Female 105 lb 5/8/2013 Other Health Professional Us
Primary
Concomitant
Pneumonitis Hospitalization 3/28/2013 77 Female 179 lb 6/26/2013 Physician Il
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization Female 159 lb 5/10/2013 Pharmacist Br
Primary
Concomitant
Malaise Life Threatening 5/9/2013 89 Female 149 lb 5/30/2013 Physician Us
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 73 Female 5/23/2013 Other Health Professional Country Not Specified
Primary
Secondary
Concomitant
Head Injury Other Serious 6/11/2013 62 Female 6/13/2013 Pharmacist Us
Primary
Concomitant
Constipation Female 229 lb 6/26/2013 Consumer Us
Primary
Concomitant
Chromatopsia Other Serious 6/17/2013 97 Male 179 lb 10/11/2013 Physician Us
Primary
Concomitant
Cardiomyopathy Death 10/9/2012 66 Male 6/27/2013 Physician Us
Primary
Concomitant
Osteomyelitis Hospitalization 9/2011 52 Female 136 lb 7/3/2013 Physician Country Not Specified
Primary
Concomitant
Dry Mouth 2010 Female 229 lb 7/9/2013 Consumer Us
Primary
Concomitant
Tardive Dyskinesia Disability 2005 Female Us
Primary
Concomitant
Throat Irritation Other Serious 7/10/2013 68 Female 7/14/2013 Us
Primary
Concomitant
Medication Residue Present 2013 Male 7/22/2013 Other Health Professional Us
Primary
Concomitant
Polychondritis Hospitalization 2007 48 Female 161 lb 7/26/2013 Consumer Br
Primary
Concomitant
Sensory Loss Other Serious 70 Female 141 lb 9/23/2013 Consumer Us
Primary
Concomitant
Pain Other Serious 2009 75 Female 150 lb 11/26/2013 Consumer Us
Primary
Concomitant
Myalgia 7/9/2013 57 Female 8/14/2013 Pharmacist Us
Primary
Concomitant
Pericardial Haemorrhage Hospitalization 5/11/2012 63 Male 240 lb 9/24/2013 Consumer Us
Primary
Concomitant
Cerebrovascular Accident Hospitalization 8/2013 85 Female 8/29/2013 Pharmacist Gb
Primary
Concomitant
Weight Bearing Difficulty Hospitalization 8/17/2013 73 Male 9/5/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Weight Bearing Difficulty Disability 8/17/2013 73 Male 9/10/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Interacting
Weight Bearing Difficulty Life Threatening 8/17/2013 73 Male 9/6/2013 Consumer Gb
Primary
Secondary
Concomitant
Weight Bearing Difficulty Disability 8/17/2013 73 Male 9/13/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/23/2013 57 Male 12/2/2013 Consumer Us
Primary
Concomitant
Weight Bearing Difficulty Hospitalization 8/17/2013 73 Male 9/16/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Weight Bearing Difficulty Disability 8/17/2013 73 Male 9/17/2013 Consumer Gb
Primary
Secondary
Concomitant
Weight Bearing Difficulty Life Threatening 8/17/2013 73 Male 9/18/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Pulmonary Thrombosis Other Serious 8/17/2013 81 Female 9/27/2013 Consumer Us
Primary
Concomitant
Respiratory Tract Infection Female 186 lb 10/1/2013 Physician Us
Primary
Concomitant
Respiratory Tract Infection Female 186 lb 10/1/2013 Physician Us
Primary
Concomitant
Therapeutic Response Decreased Female 220 lb 10/1/2013 Physician Us
Primary
Concomitant
Visual Impairment Disability 1/2012 54 Male 188 lb 10/3/2013 Other Health Professional Gb
Primary
Concomitant
Cough 1/17/2013 55 Female 156 lb 10/4/2013 Physician Us
Primary
Concomitant
Nervousness Hospitalization 4/10/2013 71 Male 227 lb 10/24/2013 Consumer Country Not Specified
Primary
Concomitant
Visual Impairment Disability 1/2012 54 Male 188 lb 10/10/2013 Other Health Professional Gb
Primary
Concomitant
Pyrexia Hospitalization 12/3/2012 74 Male 161 lb 9/3/2013 Physician Au
Primary
Secondary
Concomitant

Drug Data