Alemtuzumab combined with Fludarabine Phosphate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pneumonia Death Unknown 12/21/2005 Physician United States
Primary
Secondary
Concomitant
Cardiomyopathy Death Unknown 12/21/2005 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 12/21/2005 Physician United States
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Death 12/21/2005 Physician United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Death 12/21/2005 Physician United States
Primary
Secondary
Concomitant
Dementia Death 12/21/2005 Physician United States
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 12/21/2005 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Disease Death 12/21/2005 Physician United States
Primary
Secondary
Concomitant
Complications Of Transplant Surgery Death 12/21/2005 Physician United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Death 12/21/2005 Physician United States
Primary
Secondary
Concomitant
Pneumonia Death Unknown 12/21/2005 Physician United States
Primary
Secondary
Concomitant
Stem Cell Transplant Death Unknown 12/21/2005 Physician United States
Primary
Secondary
Concomitant
Lymphoma Transformation Hospitalization 9/1/2005 57 Male 2/15/2006 United Kingdom
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 11/15/2007 Germany
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 11/21/2007 Germany
Primary
Secondary
Concomitant
Weight Decreased Death 25 Male 11/13/2007 United Kingdom
Primary
Secondary
Obliterative Bronchiolitis Death 25 Male 12/7/2007 Physician United Kingdom
Primary
Secondary
Weight Decreased Other Serious 25 Male 12/11/2007 Other Health Professional United Kingdom
Primary
Secondary
Transplant Failure Other Serious 32 Male 1/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Proteinuria Hospitalization 12/17/2007 63 Male 150 lb 1/22/2008 Physician Germany
Primary
Secondary
Concomitant
Respiratory Moniliasis Hospitalization 61 Male 4/25/2008 Physician United Kingdom
Primary
Secondary
Respiratory Moniliasis Death 55 Female 4/25/2008 Physician United Kingdom
Primary
Secondary
Pyrexia Other Serious 4/24/2008 70 Female 168 lb 5/8/2008 Physician Germany
Primary
Secondary
Concomitant
Vertigo Death Male 5/2/2008 Germany
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 1/1/2004 Male 5/15/2008 Other Health Professional Germany
Primary
Secondary
Thrombocytopenia Other Serious 5/12/2008 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious Unknown 5/12/2008 Physician United States
Primary
Concomitant
Bone Marrow Failure Other Serious 5/12/2008 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious Unknown 5/12/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 4/9/2008 United States
Primary
Secondary
Concomitant
Vulval Cancer Other Serious 5/20/2008 United States
Primary
Secondary
Concomitant
Vulval Cancer Other Serious 5/22/2008 United States
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Death 5/30/2008 United Kingdom
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Death 6/2/2008 United Kingdom
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 7/17/2008 United States
Primary
Secondary
Concomitant
Tuberculosis Other Serious 31 Female 7/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 3 Female 7/24/2008 United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 9/29/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Pyrexia Death 7/9/2008 Other Health Professional Denmark
Primary
Secondary
Immune Reconstitution Syndrome Hospitalization 31 Female 10/14/2008 Consumer United States
Primary
Secondary
Concomitant
Neutropenia Other Serious Female 10/15/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Neutropenia Other Serious Male 10/15/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Sinus Congestion Other Serious 62 Male 10/16/2008 United Kingdom
Primary
Secondary
Neutropenia Other Serious Male 10/21/2008 Other Health Professional Denmark
Primary
Secondary
Neutropenia Other Serious Male 10/22/2008 Other Health Professional Denmark
Primary
Secondary
Pancytopenia Other Serious 1/1/2008 74 Female 10/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/28/2008 74 Female 10/21/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Oropharyngeal Pain Other Serious 5/1/2008 68 Male 161 lb 10/24/2008 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/7/2006 43 Male 671 lb 9/22/2008 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 74 Female 11/7/2008 United Kingdom
Primary
Secondary
Concomitant
Fungal Infection Other Serious 52 Female 11/10/2008 Other Health Professional United States
Primary
Concomitant
Multiple Sclerosis Death 47 Female 11/10/2008 Other Health Professional United States
Primary
Concomitant
Leukaemia Recurrent Death 46 Male 11/10/2008 Other Health Professional United States
Primary
Concomitant
Leukaemia Recurrent Death 41 Male 11/10/2008 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 8/28/2008 74 Female 11/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 74 Female 11/18/2008 United Kingdom
Primary
Secondary
Concomitant
Splenectomy Hospitalization 7 Female 11/24/2008
Primary
Secondary
Concomitant
Disease Progression Death 67 Male 12/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Rash Papular Other Serious 17 Female 12/15/2008 Other Health Professional United States
Primary
Secondary
Transplant Rejection Other Serious 2 Female 12/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Cytomegalovirus Infection Other Serious 50 Male 12/22/2008 Other Health Professional South Africa
Primary
Concomitant
Pancytopenia Other Serious 25 Male 12/22/2008 Other Health Professional South Africa
Primary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Hospitalization 24 Male 12/23/2008 Germany
Primary
Secondary
Rheumatoid Factor Positive Other Serious 1/1/2005 36 Female 1/8/2009 Consumer United Kingdom
Primary
Secondary
Aspartate Aminotransferase Increased Other Serious 1/15/2009 63 Female 143 lb 2/11/2009 United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 12/28/2008 48 2/20/2009 Physician Netherlands
Primary
Secondary
Thrombocytopenia Other Serious 1/1/2005 36 Female 2/27/2009 Consumer United Kingdom
Primary
Secondary
Weight Decreased Other Serious 2/1/2008 74 Female 3/13/2009 Physician Germany
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/1/2007 63 Male 150 lb 3/13/2009 Physician Germany
Primary
Secondary
Concomitant
Shock Other Serious 8/1/2008 41 Male 3/20/2009 Physician Germany
Primary
Secondary
Concomitant
Shock Other Serious 8/1/2008 41 Male 3/23/2009 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 4/3/2009 United States
Primary
Secondary
Pancytopenia Other Serious 1/1/2008 74 Female 4/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/6/2008 55 Male 163 lb 4/23/2009 Physician Germany
Primary
Secondary
Concomitant
Shock Other Serious 8/1/2008 41 Male 4/23/2009 Physician Germany
Primary
Secondary
Concomitant
Multi-organ Failure Death 20 5/4/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/6/2008 55 Male 161 lb 5/4/2009 Physician Germany
Primary
Secondary
Concomitant
Systemic Mycosis Death 17 5/7/2009 United Kingdom
Primary
Secondary
Concomitant
Drug Resistance Death 17 5/8/2009 United Kingdom
Primary
Secondary
Systemic Mycosis Death 17 5/12/2009 United Kingdom
Primary
Secondary
Concomitant
Septic Shock Other Serious 21 Male 5/19/2009 Other Health Professional Hong Kong
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 59 Male 5/18/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Systemic Mycosis Death 17 6/4/2009 United Kingdom
Primary
Secondary
Concomitant
Systemic Mycosis Death 17 6/5/2009 United Kingdom
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 17 Male 6/29/2009 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 17 Male 7/2/2009 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 17 Male 7/2/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 54 Female 7/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Parainfluenzae Virus Infection Other Serious 7/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Parainfluenzae Virus Infection Other Serious 7/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Hospitalization 5/11/2009 70 Male 198 lb 8/5/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Strongyloidiasis Other Serious 63 Male 8/14/2009 Physician United States
Primary
Secondary
Viral Myocarditis Other Serious 54 Female 8/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Viral Myocarditis Other Serious 54 Female 8/27/2009
Primary
Secondary
Vomiting Other Serious 11/1/2004 44 Male 8/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 7/1/2006 64 Male 8/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 10/1/2009 Male 198 lb 3/26/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 51 Female 4/1/2010 Consumer United Kingdom
Primary
Concomitant
Vertigo Hospitalization 3/20/2010 60 Male 192 lb 4/6/2010 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 31 Female 4/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Vertigo Hospitalization 3/20/2010 60 Male 4/7/2010 Physician Norway
Primary
Secondary
Concomitant
Vertigo Hospitalization 3/20/2010 60 Male 4/8/2010 Physician Norway
Primary
Secondary
Concomitant
Vertigo Hospitalization 3/20/2010 60 Male 4/27/2010 Physician Norway
Primary
Secondary
Concomitant
Vertigo Hospitalization Male 5/4/2010 Physician Norway
Primary
Secondary
Concomitant
Sepsis Other Serious 2 Male 5/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Paresis Life Threatening 4/10/2010 56 Male 5/7/2010 Physician Austria
Primary
Secondary
White Blood Cell Count Decreased Other Serious 24 Male 5/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 6/15/2010 United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 12/26/2009 64 Male 198 lb 7/14/2010 Physician Norway
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 1/1/2005 79 Male 7/16/2010 Physician United Kingdom
Primary
Secondary
Septic Shock Other Serious 8/1/2008 41 Male 7/26/2010 Physician United States
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/1/2007 63 Male 150 lb 7/26/2010 Physician Germany
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/1/2008 41 Male 7/27/2010 Physician United States
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/1/2007 63 Male 150 lb 7/27/2010 Physician Germany
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 79 Male 8/17/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 11/1/2009 49 Male 10/5/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Cytomegalovirus Viraemia Other Serious 16 12/21/2010 Other Health Professional Russian Federation
Primary
Concomitant
Enterocolitis Other Serious 12 12/21/2010 Other Health Professional Russian Federation
Primary
Concomitant
Perineal Ulceration Other Serious 0 6/30/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Convulsion Other Serious 0 7/1/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Convulsion Other Serious 0 7/6/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Convulsion Other Serious 0 7/6/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 1/1/2006 Female 8/3/2011 Other Health Professional United States
Primary
Secondary
Haemolysis Other Serious 29 Female 9/21/2011 Other Health Professional Germany
Primary
Concomitant
Cytomegalovirus Infection Other Serious 9/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Death 9/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 9/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 9/21/2011 Physician United States
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 9/21/2011 Physician United States
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 9/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 9/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Infection Hospitalization 9/22/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Epstein-barr Virus Infection Other Serious Male 9/26/2011 Other Health Professional Germany
Primary
Concomitant
Ischaemic Stroke Other Serious 9/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Other Serious 9/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 9/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 9/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 9/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 9/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Other Serious Male 10/3/2011 Other Health Professional Germany
Primary
Concomitant
Hepatitis B Other Serious 11/14/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/14/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 11/14/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Pneumonia Other Serious 11/14/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 11/14/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 11/14/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 11/14/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 11/14/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Pneumonia Other Serious 11/14/2011 Other Health Professional Italy
Primary
Secondary
Concomitant

Drug Data