Alemtuzumab combined with Cyclosporine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tracheostomy Other Serious 65 Male 2/15/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 11/15/2007 Germany
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 11/21/2007 Germany
Primary
Secondary
Concomitant
Obliterative Bronchiolitis Death 25 Male 12/7/2007 Physician United Kingdom
Primary
Secondary
Weight Decreased Other Serious 25 Male 12/11/2007 Other Health Professional United Kingdom
Primary
Secondary
Thrombotic Microangiopathy Hospitalization 2/21/2007 46 Female 12/12/2007 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 2/21/2007 46 Female 12/14/2007 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 25 Male 1/8/2008 Other Health Professional United Kingdom
Primary
Secondary
Sepsis Life Threatening 27 Female 2/15/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 33 Male 2/15/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 53 Male 2/18/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Death 15 Male 2/18/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 27 Female 2/18/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
No Therapeutic Response Death 33 Male 2/19/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Death 15 Male 2/20/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 53 Male 2/20/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 27 Female 2/20/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Death 57 Male 2/20/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Disease Progression Death 3/21/2008 United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious Male 3/27/2008 Other Health Professional Germany
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious Male 3/31/2008 Other Health Professional Germany
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death Male 4/2/2008 Germany
Primary
Secondary
Tuberculosis Other Serious 4/14/2008 United Kingdom
Primary
Concomitant
Human Herpesvirus 6 Infection Other Serious 11 Female 4/16/2008 Physician Austria
Primary
Secondary
Vertigo Death Male 5/2/2008 Germany
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 1/1/2004 Male 5/15/2008 Other Health Professional Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 5/30/2008 United Kingdom
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Death 6/2/2008 United Kingdom
Primary
Secondary
Concomitant
Streptococcal Sepsis Other Serious 6/5/2008 Germany
Primary
Secondary
Concomitant
Streptococcal Sepsis Other Serious 6/9/2008 Germany
Primary
Secondary
Concomitant
Urosepsis Other Serious 6/25/2008 Colombia
Primary
Secondary
Concomitant
Rash Life Threatening 7/14/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Rash Life Threatening 7/15/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Tuberculosis Other Serious 31 Female 7/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 3 Female 7/24/2008 United States
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 1 Male 7/25/2008 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 31 Female 8/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Hospitalization 31 Female 8/13/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 31 Female 8/21/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 31 Female 8/28/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 31 Female 9/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Human Herpesvirus 6 Infection Other Serious 7/9/2002 11 Female 9/2/2008 Other Health Professional Austria
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 9/29/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2 Female 10/3/2008 United Kingdom
Primary
Concomitant
Immune Reconstitution Syndrome Hospitalization 31 Female 10/14/2008 Consumer United States
Primary
Secondary
Concomitant
Epstein-barr Virus Infection Hospitalization 61 Female 10/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Epstein-barr Virus Infection Other Serious 61 Female 10/29/2008 United Kingdom
Primary
Secondary
Pyrexia Hospitalization 13 Female 11/11/2008 Philippines
Primary
Secondary
Concomitant
Fungal Infection Other Serious 52 Female 11/10/2008 Other Health Professional United States
Primary
Concomitant
Multiple Sclerosis Death 47 Female 11/10/2008 Other Health Professional United States
Primary
Concomitant
Leukaemia Recurrent Death 46 Male 11/10/2008 Other Health Professional United States
Primary
Concomitant
Leukaemia Recurrent Death 41 Male 11/10/2008 Other Health Professional United States
Primary
Concomitant
Stem Cell Transplant Other Serious 9 11/14/2008 United Kingdom
Primary
Secondary
Splenectomy Hospitalization 7 Female 11/24/2008
Primary
Secondary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Other Serious 1/1/2006 8 12/16/2008 United Kingdom
Primary
Secondary
Pyrexia Other Serious 61 Female 12/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Transplant Rejection Other Serious 2 Female 12/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 61 Female 12/22/2008 Consumer United Kingdom
Primary
Secondary
Cytomegalovirus Infection Other Serious 50 Male 12/22/2008 Other Health Professional South Africa
Primary
Concomitant
Pancytopenia Other Serious 25 Male 12/22/2008 Other Health Professional South Africa
Primary
Concomitant
Candida Sepsis Other Serious 37 Female 12/22/2008 Other Health Professional South Africa
Primary
Secondary
Rheumatoid Factor Positive Other Serious 1/1/2005 36 Female 1/8/2009 Consumer United Kingdom
Primary
Secondary
Rheumatoid Factor Positive Other Serious 1/1/2005 36 Female 1/21/2009 Consumer United Kingdom
Primary
Secondary
Rheumatoid Factor Positive Hospitalization 1/1/2005 36 Female 2/2/2009 Physician United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious 1/1/2005 36 Female 2/27/2009 Consumer United Kingdom
Primary
Secondary
Pyrexia Death 12/20/2006 Female 3/30/2009 Other Health Professional Korea, Republic Of
Primary
Secondary
Upper Respiratory Tract Infection Other Serious 16 Male 4/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 8 4/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Factor Positive Hospitalization 1/1/2005 36 Female 5/1/2009 Physician United Kingdom
Primary
Secondary
Rheumatoid Factor Positive Hospitalization 1/1/2005 36 Female 5/1/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Multi-organ Failure Death 20 5/4/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 11/4/2006 Male 5/4/2009 Other Health Professional Korea, Republic Of
Primary
Concomitant
Systemic Mycosis Death 17 5/7/2009 United Kingdom
Primary
Secondary
Concomitant
Engraft Failure Other Serious 5 5/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Resistance Death 17 5/8/2009 United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Other Serious 1 5/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 8 Male 5/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Engraft Failure Other Serious 5 5/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Systemic Mycosis Death 17 5/12/2009 United Kingdom
Primary
Secondary
Concomitant
Septic Shock Other Serious 21 Male 5/19/2009 Other Health Professional Hong Kong
Primary
Secondary
Concomitant
Systemic Mycosis Death 17 6/4/2009 United Kingdom
Primary
Secondary
Concomitant
Systemic Mycosis Death 17 6/5/2009 United Kingdom
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 1 6/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Cytomegalovirus Infection Other Serious 8 6/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Hypothyroidism Other Serious 16 6/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Suicidal Ideation Other Serious 17 Male 6/29/2009 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 17 Male 7/2/2009 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 17 Male 7/2/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 54 Female 7/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Encephalitis Viral Death 11/17/2006 63 7/7/2009 Other Health Professional Germany
Primary
Concomitant
Viral Myocarditis Other Serious 54 Female 8/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1 Female 8/24/2009 United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 2 Male 8/25/2009 United Kingdom
Primary
Secondary
Vomiting Other Serious 11/1/2004 44 Male 8/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 7/1/2006 64 Male 8/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2004 44 9/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 2/1/2006 45 Female 9/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 7/1/2007 56 Female 9/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 9/1/2006 52 Male 9/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 1 Female 9/10/2009 United Kingdom
Primary
Secondary
Stem Cell Transplant Other Serious 11/1/2006 34 Male 9/15/2009 United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 9/1/2006 52 Male 9/15/2009 United Kingdom
Primary
Secondary
Concomitant
Graft Versus Host Disease In Lung Other Serious 2/1/2006 45 Female 9/14/2009 United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Death 7/1/2006 64 Male 9/15/2009 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 4/1/2006 18 Male 9/15/2009 United Kingdom
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 5 Female 9/25/2009 United Kingdom
Primary
Secondary
Graft Versus Host Disease Other Serious 2 Female 9/25/2009 United Kingdom
Primary
Secondary
Sudden Death Death 59 10/1/2009 Consumer United Kingdom
Primary
Secondary
Graft Versus Host Disease Death 5 Male 10/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 2 Male 10/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Graft Versus Host Disease Other Serious 2 Female 10/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Graft Versus Host Disease Other Serious 2 Female 10/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Syncytial Virus Infection Other Serious 2 Male 10/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Graft Versus Host Disease Other Serious 4 Male 10/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Graft Versus Host Disease Other Serious 6 Female 10/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Graft Versus Host Disease Other Serious 2 Female 10/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Death 2 Female 10/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 2 Female 11/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 2 Female 11/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 2 Female 12/2/2009 United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 2 Female 11/24/2009 United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1 Female 11/30/2009 United Kingdom
Primary
Secondary
Renal Impairment Other Serious 2 Female 12/2/2009 United Kingdom
Primary
Secondary
Pemphigoid Other Serious 51 Male 2/3/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pemphigoid Other Serious 51 Male 2/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pemphigoid Other Serious 51 Male 2/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 31 Female 2/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 31 Female 2/26/2010 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 31 Female 4/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Neutropenia Death 75 Female 5/4/2010 Italy
Primary
Secondary
Concomitant
Neutropenia Death 75 Female 5/5/2010 Italy
Primary
Secondary
Concomitant
Sepsis Other Serious 2 Male 5/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 24 Male 5/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 87 Female 5/11/2010 Italy
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 87 Female 5/12/2010 Italy
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 6/17/2010 United Kingdom
Primary
Secondary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Death 6/24/2010 United Kingdom
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Death 6/24/2010 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 4 Male 8/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Encephalopathy Death 8/20/2010 United Kingdom
Primary
Secondary
Encephalopathy Death 8/24/2010 United Kingdom
Primary
Secondary
Transplant Failure Other Serious 7 Male 8/27/2010 Other Health Professional Jordan
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious Male 9/8/2010 Physician United Kingdom
Primary
Concomitant
Cytomegalovirus Infection Other Serious Female 9/8/2010 Physician United Kingdom
Primary
Concomitant
Myeloproliferative Disorder Other Serious Female 9/8/2010 Physician United Kingdom
Primary
Concomitant
Myeloproliferative Disorder Other Serious Male 9/8/2010 Physician United Kingdom
Primary
Concomitant
Encephalitis Viral Death 11/17/2006 63 10/8/2010 Germany
Primary
Concomitant
Therapeutic Response Decreased Other Serious 4/1/2009 63 Female 11/30/2010 Other Health Professional United States
Primary
Concomitant
Disease Progression Death 45 Male 11/23/2010 Physician Poland
Primary
Concomitant
T-cell Prolymphocytic Leukaemia Death 26 Male 11/23/2010 Physician Poland
Primary
Concomitant

Drug Data