Alemtuzumab combined with Cyclophosphamide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tracheostomy Other Serious 65 Male 2/15/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Lymphoma Transformation Hospitalization 9/1/2005 57 Male 2/15/2006 United Kingdom
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 11/15/2007 Germany
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 11/21/2007 Germany
Primary
Secondary
Concomitant
Rhinorrhoea Other Serious 55 Male 12/6/2007 Other Health Professional United States
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 2/21/2007 46 Female 12/12/2007 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 2/21/2007 46 Female 12/14/2007 Physician Japan
Primary
Concomitant
Rhinorrhoea Other Serious 55 Male 12/14/2007 Other Health Professional United States
Primary
Concomitant
Transplant Failure Other Serious 32 Male 1/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Proteinuria Hospitalization 12/17/2007 63 Male 150 lb 1/22/2008 Physician Germany
Primary
Secondary
Concomitant
Stenotrophomonas Infection Other Serious 2/19/2008 United States
Primary
Secondary
Drug Eruption Hospitalization 1/2/2008 58 Male 174 lb 2/28/2008 Physician Germany
Primary
Secondary
Concomitant
Disease Progression Death 3/21/2008 United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious Male 3/27/2008 Other Health Professional Germany
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious Male 3/31/2008 Other Health Professional Germany
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death Male 4/2/2008 Germany
Primary
Secondary
Weight Decreased Hospitalization 2/1/2008 74 Female 4/3/2008 Physician Germany
Primary
Secondary
Concomitant
Respiratory Moniliasis Hospitalization 61 Male 4/25/2008 Physician United Kingdom
Primary
Secondary
Respiratory Moniliasis Death 55 Female 4/25/2008 Physician United Kingdom
Primary
Secondary
Pyrexia Other Serious 4/24/2008 70 Female 168 lb 5/8/2008 Physician Germany
Primary
Secondary
Concomitant
Vertigo Death Male 5/2/2008 Germany
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 1/1/2004 Male 5/15/2008 Other Health Professional Germany
Primary
Secondary
Thrombocytopenia Other Serious 5/12/2008 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious Unknown 5/12/2008 Physician United States
Primary
Concomitant
Bone Marrow Failure Other Serious 5/12/2008 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious Unknown 5/12/2008 Physician United States
Primary
Concomitant
Vulval Cancer Other Serious 5/20/2008 United States
Primary
Secondary
Concomitant
Vulval Cancer Other Serious 5/22/2008 United States
Primary
Secondary
Concomitant
Sepsis Death 62 Male 6/5/2008 Other Health Professional Austria
Primary
Secondary
Sepsis Death 62 Male 6/10/2008 Other Health Professional Austria
Primary
Secondary
Respiratory Failure Other Serious 64 Female 6/13/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Zygomycosis Death 62 Male 6/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Zygomycosis Death 62 Male 6/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Viraemia Other Serious 6/20/2008 South Africa
Primary
Secondary
Concomitant
Viraemia Other Serious 6/23/2008 South Africa
Primary
Secondary
Concomitant
T-cell Lymphoma Other Serious 11/1/2006 41 Male 7/10/2008 Netherlands
Primary
Secondary
Concomitant
T-cell Lymphoma Recurrent Other Serious 8/1/2006 32 Female 7/11/2008 Netherlands
Primary
Secondary
Concomitant
T-cell Lymphoma Recurrent Other Serious 8/1/2006 32 Female 7/14/2008 Netherlands
Primary
Secondary
Concomitant
Tuberculosis Other Serious 31 Female 7/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 31 Female 8/7/2008 United Kingdom
Primary
Secondary
Vomiting Other Serious 31 Female 8/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Hospitalization 31 Female 8/13/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 31 Female 8/13/2008 United Kingdom
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Other Serious 12/1/2006 41 Male 8/21/2008 Other Health Professional Netherlands
Primary
Secondary
Vomiting Other Serious 31 Female 8/21/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 31 Female 8/22/2008 United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 9/29/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Hospitalization 31 Female 10/14/2008 Consumer United States
Primary
Secondary
Concomitant
Oropharyngeal Pain Other Serious 5/1/2008 68 Male 161 lb 10/22/2008 Physician Germany
Primary
Secondary
Concomitant
Pancytopenia Other Serious 1/1/2008 74 Female 10/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/28/2008 74 Female 10/21/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Oropharyngeal Pain Other Serious 5/1/2008 68 Male 161 lb 10/24/2008 Physician Germany
Primary
Secondary
Concomitant
Pancytopenia Other Serious 74 Female 11/7/2008 United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/28/2008 74 Female 11/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 9 11/14/2008 United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious 74 Female 11/18/2008 United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/22/2008 56 Female 12/1/2008 Physician Germany
Primary
Secondary
Concomitant
Circulatory Collapse Hospitalization 11/19/2008 69 Female 12/1/2008 Physician Germany
Primary
Secondary
Concomitant
Disease Progression Death 67 Male 12/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Epstein-barr Virus Associated Lymphoproliferative Disorder Other Serious 1/1/2006 8 12/16/2008 United Kingdom
Primary
Secondary
Cytomegalovirus Infection Other Serious 50 Male 12/22/2008 Other Health Professional South Africa
Primary
Concomitant
Pancytopenia Other Serious 25 Male 12/22/2008 Other Health Professional South Africa
Primary
Concomitant
Pulmonary Mycosis Hospitalization 11/1/2008 69 Female 1/15/2009 Physician Germany
Primary
Secondary
Concomitant
B-cell Lymphoma Hospitalization 59 Male 1/27/2009 Germany
Primary
Secondary
Concomitant
B-cell Lymphoma Death 63 Female 1/27/2009 Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/28/2008 48 2/20/2009 Physician Netherlands
Primary
Secondary
Weight Decreased Other Serious 2/1/2008 74 Female 3/13/2009 Physician Germany
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/1/2007 63 Male 150 lb 3/13/2009 Physician Germany
Primary
Secondary
Concomitant
Haematuria Hospitalization 1/24/2009 64 Female 3/16/2009 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/22/2008 56 Female 3/16/2009 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/22/2008 56 Female 3/16/2009 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Mycosis Hospitalization 11/19/2008 69 Female 3/16/2009 Physician Germany
Primary
Secondary
Concomitant
Shock Other Serious 8/1/2008 41 Male 3/20/2009 Physician Germany
Primary
Secondary
Concomitant
Shock Other Serious 8/1/2008 41 Male 3/23/2009 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8 4/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 4/3/2009 United States
Primary
Secondary
Pancytopenia Other Serious 1/1/2008 74 Female 4/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/1/2007 63 Male 150 lb 4/22/2009 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/6/2008 55 Male 163 lb 4/23/2009 Physician Germany
Primary
Secondary
Concomitant
Shock Other Serious 8/1/2008 41 Male 4/23/2009 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/6/2008 55 Male 161 lb 5/4/2009 Physician Germany
Primary
Secondary
Concomitant
Engraft Failure Other Serious 5 5/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 1 5/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 8 Male 5/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Engraft Failure Other Serious 5 5/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypothyroidism Other Serious 15 5/12/2009 United Kingdom
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 59 Male 5/18/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 18 6/1/2009 Other Health Professional United Kingdom
Primary
Secondary
Haematuria Hospitalization 1/24/2009 64 Female 6/5/2009 Physician Germany
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 1 6/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Cytomegalovirus Infection Other Serious 8 6/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Hypothyroidism Other Serious 16 6/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Polyomavirus-associated Nephropathy Hospitalization 50 Male 6/15/2009 Other Health Professional United States
Primary
Secondary
Suicidal Ideation Other Serious 17 Male 6/29/2009 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 17 Male 7/2/2009 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 17 Male 7/2/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/11/2009 43 Male 6/30/2009 Pharmacist United States
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 7/9/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 7/9/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 7/9/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 7/9/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 7/9/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 7/9/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 7/9/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 7/9/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Sepsis Other Serious 7/9/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 5/11/2009 70 Male 198 lb 8/5/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Tenderness Other Serious 63 Male 8/13/2009 Physician United States
Primary
Secondary
Renal Impairment Other Serious 1 Female 8/24/2009 United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 2 Male 8/25/2009 United Kingdom
Primary
Secondary
Stem Cell Transplant Other Serious 1 Female 9/10/2009 United Kingdom
Primary
Secondary
Stem Cell Transplant Other Serious 11/1/2006 34 Male 9/15/2009 United Kingdom
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 5 Female 9/25/2009 United Kingdom
Primary
Secondary
Graft Versus Host Disease Other Serious 2 Female 9/25/2009 United Kingdom
Primary
Secondary
Epstein-barr Virus Associated Lymphoproliferative Disorder Death 53 Male 9/28/2009 Italy
Primary
Secondary
Sudden Death Death 59 10/1/2009 Consumer United Kingdom
Primary
Secondary
Graft Versus Host Disease Death 5 Male 10/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 2 Male 10/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Graft Versus Host Disease Other Serious 2 Female 10/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Graft Versus Host Disease Other Serious 2 Female 10/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Syncytial Virus Infection Other Serious 2 Male 10/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Graft Versus Host Disease Other Serious 4 Male 10/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Graft Versus Host Disease Other Serious 6 Female 10/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Graft Versus Host Disease Other Serious 2 Female 10/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Death 2 Female 10/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Pyrexia Hospitalization 48 Female 11/13/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Pyrexia Hospitalization 48 Female 11/18/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2 Female 11/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 2 Female 11/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 2 Female 12/2/2009 United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 2 Female 11/24/2009 United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1 Female 11/30/2009 United Kingdom
Primary
Secondary
Renal Impairment Other Serious 2 Female 12/2/2009 United Kingdom
Primary
Secondary
Weight Decreased Other Serious 40 Male 12/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Gene Mutation Other Serious 7/25/2007 52 Male 12/29/2009 Czech Republic
Primary
Concomitant
Gene Mutation Other Serious 11/22/2006 60 Female 12/29/2009 Czech Republic
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 10/1/2009 Male 198 lb 12/31/2009 Physician United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 5/1/2008 Male 172 lb 2/4/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 31 Female 2/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 31 Female 2/26/2010 United Kingdom
Primary
Secondary
Concomitant
Pyrexia 10/22/2008 56 Female 6/12/2009 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Mycosis 11/19/2008 69 Female 6/12/2009 Physician Germany
Primary
Secondary
Concomitant
Viral Test Positive Other Serious 1/1/2010 62 Male 3/18/2010 Physician Germany
Primary
Secondary
Concomitant
Viral Test Positive Other Serious 1/1/2010 62 Male 3/19/2010 Physician Germany
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 10/1/2009 Male 198 lb 3/26/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 3/1/2005 79 Male 4/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 3/20/2010 60 Male 192 lb 4/6/2010 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 31 Female 4/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Vertigo Hospitalization 3/20/2010 60 Male 4/7/2010 Physician Norway
Primary
Secondary
Concomitant
Vertigo Hospitalization 3/20/2010 60 Male 4/8/2010 Physician Norway
Primary
Secondary
Concomitant

Drug Data