Aldactone combined with Warfarin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hepatic Function Abnormal Other Serious 10/1/2005 71 Male 1/3/2006 Physician Japan
Primary
Concomitant
Basedow's Disease Hospitalization 34 Female 2/2/2006 Consumer United States
Primary
Secondary
Concomitant
Oliguria Other Serious 12/7/2005 61 Male 291 lb 2/21/2006 Physician Canada
Primary
Concomitant
Somnolence Other Serious 1/1/2003 79 Male 77 lb 3/11/2006 Physician Japan
Primary
Concomitant
Somnolence Other Serious 1/1/2003 79 Male 77 lb 3/21/2006 Physician Japan
Primary
Concomitant
Vision Blurred Life Threatening 6/1/2003 16 Female 102 lb 3/20/2006 Japan
Primary
Concomitant
Oral Intake Reduced Life Threatening 1/2/2006 80 Female 114 lb 3/21/2006 Physician Japan
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/1/2005 83 Female 3/30/2006 Pharmacist Canada
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/1/2006 83 Female 4/4/2006 Pharmacist Canada
Primary
Concomitant
Pericardial Effusion Life Threatening 1/23/2006 12 Female 66 lb 4/14/2006 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 7/29/2005 77 Male 225 lb 6/8/2006 Consumer France
Primary
Secondary
Concomitant
Vomiting Other Serious 3/30/2006 59 Female 8/1/2006 Physician United States
Primary
Secondary
Concomitant
Asthma 1/1/2005 53 Female 249 lb 1/23/2007 Other Health Professional United States
Primary
Concomitant
Cardioversion Other Serious 3/1/2006 Male 143 lb 5/11/2007 Physician Australia
Primary
Concomitant
Somnolence Other Serious 1/1/2003 79 Male 77 lb 5/13/2007 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Death 1/1/2004 43 Male 5/13/2007 Other Health Professional United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Life Threatening 7/30/2007 70 Female 8/9/2007 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 9/14/2006 78 Male 8/16/2007 Physician Japan
Primary
Concomitant
Encephalopathy Life Threatening 10/20/2004 73 Male 8/17/2007 Other Health Professional Japan
Primary
Concomitant
Blood Creatinine Increased Other Serious 7/20/2007 87 Female 8/21/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 7/20/2007 87 Female 8/30/2007 Physician Japan
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Life Threatening 7/30/2007 70 Female 10/16/2007 Physician Japan
Primary
Concomitant
Portal Venous Gas Life Threatening 11/13/2008 12/11/2008 Other Health Professional Japan
Primary
Concomitant
Ventricular Tachycardia Hospitalization 12/4/2008 87 Female 116 lb 12/30/2008 Physician Japan
Primary
Concomitant
Suicidal Ideation Other Serious 9/1/2008 Male 1/1/2009 Physician Japan
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 11/28/2008 52 Male 1/6/2009 Physician Japan
Primary
Secondary
Concomitant
Mental Disorder Other Serious 11/6/2008 Female 4/27/2009 Physician Japan
Primary
Secondary
Concomitant
Portal Vein Thrombosis Hospitalization Male 4/28/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/17/2009 92 Male 156 lb 5/19/2009 Pharmacist United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 5/7/2009 89 Female 93 lb 6/19/2009 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 12/15/2008 76 Male 161 lb 7/2/2009 Physician Japan
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 5/7/2009 89 Female 93 lb 7/2/2009 Physician Japan
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 4/15/2009 Female 119 lb 7/6/2009 Physician Japan
Primary
Concomitant
Interacting
Interstitial Lung Disease Life Threatening 6/11/2009 76 Male 95 lb 7/10/2009 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Hospitalization Male 121 lb 8/10/2009 Physician Japan
Primary
Concomitant
Rash Generalised Other Serious 7/29/2009 58 Male 8/12/2009 Other Health Professional United States
Primary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 5/12/2009 69 8/12/2009 Japan
Primary
Concomitant
Unevaluable Event Hospitalization 47 Male 8/11/2009 United States
Primary
Concomitant
Hyperkalaemia Hospitalization 6/22/2005 Male 8/21/2009 Physician Canada
Primary
Concomitant
Rash 7/6/2009 Male 275 lb 8/23/2009 United States
Primary
Concomitant
Rash Generalised Other Serious 7/29/2009 58 Male 8/25/2009 Other Health Professional United States
Primary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 5/12/2009 69 8/28/2009 Japan
Primary
Concomitant
Hyperkalaemia Hospitalization 6/22/2005 Male 8/28/2009 Physician Canada
Primary
Concomitant
Pneumonia Aspiration Hospitalization 5/12/2009 69 9/4/2009 Japan
Primary
Concomitant
Surgery Hospitalization 47 Male 9/3/2009 United States
Primary
Concomitant
Vomiting Other Serious 82 Female 9/10/2009 United States
Primary
Concomitant
Ventricular Failure Hospitalization 49 Female 9/14/2009 United States
Primary
Concomitant
Weight Increased Other Serious 31 Male 9/15/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 79 Male 12/11/2009 United States
Primary
Concomitant
Urticaria Other Serious 10/10/2009 64 Male 146 lb 12/31/2009 Physician Japan
Primary
Secondary
Concomitant
Shock Other Serious 12/1/2007 71 Male 322 lb 12/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperuricaemia Other Serious 10/26/2009 82 Male 136 lb 1/22/2010 Physician Japan
Primary
Concomitant
Cardiac Disorder Hospitalization 11/1/2009 Male 165 lb 1/25/2010 Consumer Brazil
Primary
Concomitant
Weight Increased Other Serious 12/1/2007 74 Female 163 lb 2/3/2010 Other Health Professional United States
Primary
Concomitant
Skin Tightness Death 1/1/2004 43 Male 115 lb 2/15/2010 United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 2/4/2010 Male 2/28/2010 Physician Japan
Primary
Concomitant
Anaphylactic Shock Other Serious 2/22/2010 82 Female 3/16/2010 Japan
Primary
Concomitant
Anaphylactic Shock Other Serious 2/22/2010 82 Female 3/25/2010 Japan
Primary
Concomitant
Weight Decreased Hospitalization 8/4/2009 61 Female 134 lb 5/6/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 11/19/2007 71 Male 5/7/2010 Other Health Professional United States
Primary
Concomitant
Injection Site Warmth Hospitalization 8/27/2008 70 Male 5/17/2010 Japan
Primary
Concomitant
Injection Site Warmth 8/27/2008 70 Male 6/2/2010 Other Health Professional Japan
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 30 Male 226 lb 6/1/2010 United States
Primary
Concomitant
Localised Infection Other Serious 1/1/2005 50 Female 154 lb 6/8/2010 Consumer Brazil
Primary
Secondary
Concomitant
Thrombosis Other Serious 2/13/2008 75 Female 170 lb 6/10/2010 Lawyer United States
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2008 71 Male 154 lb 6/11/2010 Consumer Brazil
Primary
Secondary
Concomitant
Cardiac Failure Death 4/19/2010 86 Male 6/12/2010 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 4/1/2009 57 Female 86 lb 6/16/2010 Physician Japan
Primary
Concomitant
Urine Output Decreased Other Serious 1/6/2010 47 Male 132 lb 6/24/2010 Physician Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 2/26/2010 68 Female 106 lb 6/24/2010 Other Health Professional Japan
Primary
Concomitant
Interacting
Oedema Other Serious 6/4/2010 86 Female 6/22/2010 Consumer Japan
Primary
Secondary
Oedema Other Serious 6/4/2010 86 Female 6/24/2010 Consumer Japan
Primary
Secondary
Pneumonia Other Serious 1/1/2008 76 Male 112 lb 7/5/2010 Physician Japan
Primary
Concomitant
Haematuria Other Serious Female 7/5/2010 Pharmacist Japan
Primary
Concomitant
Platelet Count Decreased Male 7/7/2010 United States
Primary
Concomitant
Alopecia Other Serious 11/21/2009 69 Male 108 lb 7/9/2010 Physician
Primary
Concomitant
Hypokalaemia Other Serious 6/22/2010 66 Male 143 lb 7/15/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 55 Male 254 lb 7/8/2010 United States
Primary
Concomitant
Mouth Haemorrhage Disability 5/1/2009 77 Female 95 lb 7/26/2010 Physician Japan
Primary
Concomitant
Interacting
Urine Output Decreased Other Serious 1/6/2010 47 Male 132 lb 7/26/2010 Physician Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 6/16/2010 42 Female 8/4/2010 Physician Japan
Primary
Concomitant
Interacting
Vomiting Other Serious 3/1/2008 26 Male 8/5/2010 Lawyer United States
Primary
Concomitant
Staphylococcal Infection Other Serious 2/1/2008 75 Female 170 lb 8/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/10/2009 50 Female 84 lb 8/6/2010 Physician Japan
Primary
Concomitant
Interacting
Liver Disorder Hospitalization 11/28/2008 54 Male 8/10/2010 Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 11/28/2008 54 Male 8/11/2010 Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 11/28/2008 54 Male 8/16/2010 Physician Japan
Primary
Secondary
Concomitant
Death Death 2/16/2009 56 Male 118 lb 8/26/2010 Physician Japan
Primary
Concomitant
Renal Impairment Death 6/17/2010 60 Male 9/8/2010 Pharmacist Japan
Primary
Concomitant
Hepatitis Acute Hospitalization 11/27/2008 52 Male 9/9/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Malaise Other Serious 2/26/2010 68 Female 106 lb 9/9/2010 Other Health Professional Japan
Primary
Concomitant
Interacting
Hepatitis Acute Other Serious 11/27/2008 52 Male 130 lb 9/9/2010 Physician
Primary
Secondary
Death Death 8/11/2010 49 Male 139 lb 9/9/2010 Physician Japan
Primary
Concomitant
Syncope Other Serious 7/1/2010 78 Male 154 lb 9/10/2010 Physician Japan
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 2/16/2009 56 Male 118 lb 9/13/2010 Physician Japan
Primary
Concomitant
Hepatitis Acute Other Serious 11/27/2008 52 Male 9/14/2010 Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 5/5/2010 75 Female 90 lb 8/27/2010 Japan
Primary
Secondary
Concomitant
Hepatitis Acute Other Serious 11/27/2008 53 Male 9/21/2010 Physician Italy
Primary
Secondary
Concomitant
Syncope Other Serious 7/1/2010 78 Male 154 lb 9/21/2010 Physician Japan
Primary
Secondary
Concomitant
Deep Vein Thrombosis Death 9/5/2010 49 Female 9/17/2010 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/9/2010 43 Male 143 lb 9/22/2010 Other Health Professional Japan
Primary
Concomitant
Deep Vein Thrombosis Hospitalization Female 9/23/2010 Physician United States
Primary
Concomitant
Hepatitis Acute Other Serious 11/27/2008 53 Male 9/24/2010 Physician Italy
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 6/22/2009 75 Female 9/27/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/1/2010 77 Male 153 lb 9/28/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 11/27/2008 52 Male 10/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 11/12/2009 56 Female 10/19/2010 Physician Japan
Primary
Concomitant
Pruritus Female 158 lb 10/21/2010 Consumer United States
Primary
Concomitant
Infection Hospitalization 7/1/2010 81 Female 88 lb 10/29/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 9/12/2010 79 Male 10/29/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious Male 11/2/2010 Physician Ireland
Primary
Concomitant
Ventricular Fibrillation Other Serious 11/19/2007 71 Male 11/2/2010 Lawyer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 9/15/2009 74 Male 11/5/2010 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 11/12/2009 56 Female 11/5/2010 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 9/27/2010 53 Male 157 lb 11/10/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 2/16/2009 56 Male 118 lb 11/11/2010 Physician Japan
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 76 Female 11/2/2010 United States
Primary
Concomitant
Urine Output Decreased Other Serious 1/6/2010 47 Male 132 lb 11/12/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Hospitalization 9/27/2010 80 Male 154 lb 11/18/2010 Physician Japan
Primary
Concomitant
Renal Impairment Death 6/17/2010 60 Male 11/19/2010 Pharmacist Japan
Primary
Concomitant
Torsade De Pointes Other Serious Male 11/30/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2010 68 Male 130 lb 11/30/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious Male 12/6/2010 Physician Ireland
Primary
Concomitant
Dysgeusia Other Serious Female 12/6/2010 Pharmacist Ireland
Primary
Concomitant
Pneumonia Aspiration Hospitalization 5/12/2009 69 Female 116 lb 12/3/2010 Japan
Primary
Concomitant
Cardiac Failure Chronic Other Serious 11/13/2010 84 Female 82 lb 12/10/2010 Physician Japan
Primary
Concomitant
Pain In Extremity Other Serious 12/21/2010 Physician Japan
Primary
Concomitant
Hyponatraemia Hospitalization 1/1/2010 75 Male 12/22/2010 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 10/28/2010 75 Female 12/23/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Dizziness Hospitalization 11/1/2009 88 Female 12/27/2010 Physician Japan
Primary
Secondary
Concomitant
Injection Site Haemorrhage Life Threatening 10/23/2010 88 Male 110 lb 12/29/2010 Physician Japan
Primary
Secondary
Concomitant
Hyperkalaemia Life Threatening 10/11/2010 78 Male 12/30/2010 Physician Slovenia
Primary
Secondary
Concomitant
Cardiac Arrest Death 9/1/2009 Female 88 lb 12/31/2010 Physician Japan
Primary
Concomitant
Diarrhoea Hospitalization 11/25/2010 65 Male 99 lb 1/5/2011 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Death 11/8/2010 76 Female 73 lb 1/12/2011 Physician Japan
Primary
Concomitant
Pruritus Female 158 lb 1/21/2011 Consumer United States
Primary
Concomitant
Blood Gastrin Increased Other Serious 10 Male 1/31/2011 Physician Japan
Primary
Concomitant
Right Ventricular Failure Other Serious 7/1/2010 43 Female 2/1/2011 Physician Japan
Primary
Concomitant
Torsade De Pointes Other Serious 10/13/2010 70 Male 195 lb 2/1/2011 Physician United States
Primary
Concomitant
Cardiac Arrest Death 9/1/2009 Female 88 lb 2/1/2011 Physician Japan
Primary
Concomitant
Apnoeic Attack Hospitalization 12/22/2010 77 Male 101 lb 2/3/2011 Physician Japan
Primary
Secondary
Concomitant
Hypotension Other Serious 2/1/2008 75 Female 170 lb 2/3/2011 Lawyer United States
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 1/1/2010 83 Male 2/7/2011 Physician United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 80 Male 1/28/2011 United States
Primary
Concomitant
Dizziness Death 10/9/2009 81 Male 2/14/2011 Physician Ireland
Primary
Concomitant
Pneumonia Hospitalization 12/21/2010 77 Male 101 lb 2/18/2011 Physician Japan
Primary
Secondary
Concomitant
Sick Sinus Syndrome Hospitalization 2/11/2011 75 Female 2/18/2011 Physician Japan
Primary
Concomitant

Drug Data