Aldactone combined with Sildenafil Citrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Right Ventricular Failure Hospitalization 4/8/2005 33 Female 126 lb 3/22/2006 Consumer United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 6/29/2005 43 Male 180 lb 5/2/2006 Other Health Professional United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2006 9 Female 5/5/2006 Physician Brazil
Primary
Concomitant
Syncope Hospitalization 2/20/2006 67 Female 135 lb 5/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2006 9 Female 5/16/2006 Physician Brazil
Primary
Concomitant
Bronchitis Acute Hospitalization 53 Female 84 lb 5/23/2006 Physician Japan
Primary
Concomitant
Ventricular Hypokinesia Other Serious 11/1/2005 41 Male 289 lb 5/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Facial Palsy Other Serious 5/26/2003 36 Male 187 lb 7/24/2006 Physician Japan
Primary
Concomitant
Uterine Haemorrhage Hospitalization 11/16/2005 33 Female 115 lb 7/24/2006 Physician Japan
Primary
Concomitant
Right Ventricular Failure Other Serious 7/31/2004 26 Female 149 lb 7/24/2006 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 10/7/2004 51 Female 7/24/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/17/2006 44 Female 175 lb 7/31/2006 Physician United States
Primary
Concomitant
Right Ventricular Failure Death 4/1/2004 31 Female 128 lb 8/1/2006 Physician Japan
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 2/12/2005 34 Female 158 lb 8/22/2006 Consumer United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 11/1/2005 41 Male 8/23/2006 Physician United States
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 1/1/2006 9 Female 8/29/2006 Physician Brazil
Primary
Concomitant
Therapy Regimen Changed Other Serious 1/1/2003 9 Female 9/1/2006 Physician Brazil
Primary
Concomitant
Ventricular Failure Other Serious 1/1/2003 9 Female 10/25/2006 Physician Brazil
Primary
Concomitant
Off Label Use 36 Male 187 lb 11/30/2006 Physician Japan
Primary
Concomitant
Right Ventricular Failure 45 Female 115 lb 11/30/2006 Physician Japan
Primary
Concomitant
Uterine Haemorrhage Hospitalization 11/16/2005 33 Female 115 lb 11/30/2006 Physician Japan
Primary
Concomitant
Right Ventricular Failure Hospitalization 10/7/2004 51 Female 11/30/2006 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 7/31/2004 26 Female 149 lb 11/30/2006 Physician Japan
Primary
Secondary
Concomitant
Off Label Use 41 Female 115 lb 11/30/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Vein Stenosis Hospitalization 4/2/2006 53 Female 100 lb 11/30/2006 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure 32 Female 139 lb 11/30/2006 Physician Japan
Primary
Concomitant
Pulmonary Hypertension Hospitalization 4/20/2005 38 Female 101 lb 11/30/2006 Physician Japan
Primary
Concomitant
Right Ventricular Failure Death 4/1/2004 31 Female 128 lb 11/30/2006 Physician Japan
Primary
Concomitant
Weight Increased 22 Female 148 lb 11/30/2006 Physician Japan
Primary
Concomitant
Off Label Use Hospitalization 12/12/2005 53 Female 84 lb 11/30/2006 Physician Japan
Primary
Concomitant
Musculoskeletal Pain 6/1/2006 69 Male 182 lb 10/24/2006 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Other Serious 8/8/2006 64 Female 1/30/2007 Physician United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 10/7/2006 0 Female 9 lb 2/23/2007 Consumer Switzerland
Primary
Secondary
Concomitant
Red Blood Cell Schistocytes Present Other Serious 8/8/2006 64 Female 2/23/2007 Physician United States
Primary
Concomitant
Respiratory Disorder Hospitalization 3/1/2007 74 Male 3/20/2007 Pharmacist France
Primary
Concomitant
Fatigue 1/1/2005 50 Female 143 lb 1/23/2007 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 11/8/2006 55 Female 174 lb 1/23/2007 Consumer United States
Primary
Concomitant
Dizziness 10/23/2006 68 Female 235 lb 1/23/2007 Consumer United States
Primary
Concomitant
Renal Impairment 10/1/2006 43 Female 175 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Fatigue 56 Female 140 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 1/1/2006 Female 196 lb 4/25/2007 Physician France
Primary
Secondary
Concomitant
Sepsis Required Intervention 3/29/2007 58 Female 132 lb 5/8/2007 Physician Germany
Primary
Concomitant
Pleural Effusion Hospitalization 4/4/2007 Female 148 lb 8/10/2007 Physician United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 10/22/2007 Female 112 lb 11/27/2007 Physician Japan
Primary
Secondary
Thrombocytopenia Other Serious 11/5/2007 66 Male 11/29/2007 Physician France
Primary
Concomitant
Off Label Use Required Intervention 10/1/2007 67 Female 1/3/2008 Other Health Professional United States
Primary
Concomitant
Scleroderma Death 1/8/2004 66 Female 140 lb 2/29/2008 Physician United States
Primary
Concomitant
Pulmonary Hypertension Required Intervention 10/1/2007 67 Female 5/6/2008 Physician United States
Primary
Concomitant
Drug Ineffective Death 8/1/2006 Female 8/19/2008 Pharmacist France
Primary
Concomitant
Right Ventricular Failure Hospitalization Female 179 lb 9/25/2008 Physician United States
Primary
Concomitant
Hepatic Failure Death 5/5/2008 12/17/2008 Physician Japan
Primary
Concomitant
Syncope Hospitalization 8/29/2008 Female 244 lb 12/17/2008 Physician United States
Primary
Concomitant
Respiratory Failure Death 6/12/2008 12/23/2008 Physician Japan
Primary
Concomitant
Respiratory Failure Death 12/4/2008 12/31/2008 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/29/2008 Female 244 lb 1/5/2009 Physician United States
Primary
Concomitant
Death Death 7/16/2008 Female 86 lb 1/6/2009 Physician Japan
Primary
Concomitant
Vomiting Death 8/26/2008 29 Female 133 lb 12/17/2008 Physician United States
Primary
Concomitant
Respiratory Failure Death 12/4/2008 1/22/2009 Physician Japan
Primary
Concomitant
Respiratory Failure Death 11/17/2008 2/3/2009 Physician Japan
Primary
Concomitant
Cardiac Failure Other Serious 7/22/2008 Female 88 lb 2/17/2009 Physician Japan
Primary
Concomitant
Death Death 3/4/2009 3/23/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 5/12/2008 3/23/2009 Physician Japan
Primary
Concomitant
Urinary Retention Hospitalization 9/30/2008 3/24/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Death Death 3/4/2009 3/31/2009 Physician Japan
Primary
Concomitant
Syncope Hospitalization 5/31/2004 Female 95 lb 4/10/2009 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 5/31/2004 Female 95 lb 4/16/2009 Physician United States
Primary
Concomitant
Urinary Retention Other Serious 9/30/2008 Male 4/20/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 3/9/2009 66 5/14/2009 Physician India
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 3/9/2009 66 5/25/2009 Physician India
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 5/12/2008 32 6/1/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 5/12/2008 32 6/1/2009 Physician Japan
Primary
Concomitant
Pancreatitis Hospitalization Female 123 lb 7/6/2009 Physician United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 7/21/2009 Male 8/11/2009 Physician France
Primary
Concomitant
Renal Failure Life Threatening 5/25/2009 65 8/18/2009 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 5/12/2009 66 8/19/2009 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 5/25/2009 65 8/27/2009 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 4/29/2008 29 9/2/2009 Physician Japan
Primary
Concomitant
Death Death 5/1/2009 80 9/8/2009 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 4/29/2008 29 9/15/2009 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 5/12/2009 66 9/23/2009 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 5/12/2009 66 10/12/2009 Physician Japan
Primary
Secondary
Concomitant
Death Death 5/1/2009 80 10/14/2009 Physician Japan
Primary
Concomitant
Tongue Disorder Other Serious 1/1/2009 30 Female 104 lb 11/24/2009 Consumer Brazil
Primary
Concomitant
Pulmonary Oedema Hospitalization 11/10/2009 80 Female 11/25/2009 Jordan
Primary
Concomitant
Pulmonary Oedema Hospitalization 80 Female 12/1/2009 Jordan
Primary
Concomitant
Hyperkalaemia Hospitalization 3/9/2009 66 Male 132 lb 12/9/2009 Physician India
Primary
Secondary
Concomitant
Atrial Flutter Hospitalization 6/1/2004 Female 160 lb 12/23/2009 Consumer United States
Primary
Secondary
Concomitant
Death Death 75 Female 101 lb 12/29/2009 Physician Japan
Primary
Concomitant
Restlessness Other Serious 3/4/2009 Male 6 lb 1/5/2010 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Death 75 Female 101 lb 12/31/2009 Physician Japan
Primary
Concomitant
Death Death 7/9/2009 1 Male 7 lb 1/15/2010 Physician Japan
Primary
Concomitant
Restlessness Other Serious 3/4/2009 0 Male 6 lb 1/25/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/28/2010 Female 11 lb 2/11/2010 Consumer Philippines
Primary
Concomitant
Death Death 12/20/2009 45 Female 86 lb 2/16/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Death 7/9/2009 1 Male 7 lb 2/16/2010 Physician Japan
Primary
Concomitant
Pulmonary Veno-occlusive Disease Other Serious 7/31/2008 32 Male 129 lb 2/23/2010 Physician Japan
Primary
Concomitant
Right Ventricular Failure Other Serious 12/20/2009 45 Female 86 lb 3/2/2010 Physician Japan
Primary
Concomitant
Pulmonary Hypertension Other Serious 70 Female 110 lb 3/16/2010 Physician Japan
Primary
Concomitant
Pulmonary Oedema Other Serious 7 Male 5/21/2010 Other Health Professional United States
Primary
Concomitant
Death Death 2/26/2010 17 Female 74 lb 6/1/2010 Physician Japan
Primary
Concomitant
Cardiac Failure Death 17 Female 74 lb 6/11/2010 Physician Japan
Primary
Concomitant
Anaemia Hospitalization 4/9/2009 60 Female 108 lb 7/1/2010 Physician Japan
Primary
Secondary
Concomitant
Death Death 2/16/2009 56 Male 118 lb 8/26/2010 Physician Japan
Primary
Concomitant
Myocardial Ischaemia Death 2/16/2009 56 Male 118 lb 9/13/2010 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Other Serious 7/13/2008 14 Female 79 lb 9/16/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 83 Female 108 lb 9/3/2010 United States
Primary
Concomitant
Right Ventricular Failure Other Serious 18 Male 9/28/2010 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 11/12/2009 56 Female 10/19/2010 Physician Japan
Primary
Concomitant
Death Death 23 Male 112 lb 10/28/2010 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Other Serious 7/13/2008 14 Female 79 lb 11/3/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 11/12/2009 56 Female 11/5/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/1/2010 67 Male 11/5/2010 Other Health Professional France
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 18 Male 11/10/2010 Physician Japan
Primary
Concomitant
Myocardial Ischaemia Death 2/16/2009 56 Male 118 lb 11/11/2010 Physician Japan
Primary
Concomitant
Death Death 3/24/2007 12/6/2010 Physician United States
Primary
Concomitant
Atrial Flutter Hospitalization 6/1/2004 58 Female 160 lb 12/23/2009 Consumer United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Death 11/8/2010 76 Female 73 lb 1/12/2011 Physician Japan
Primary
Concomitant
Qrs Axis Abnormal Death 7/13/2008 14 Female 79 lb 1/13/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Arterial Hypertension Death 67 Female 2/3/2011 Other Health Professional Australia
Primary
Concomitant
Right Ventricular Failure Death 67 Female 2/3/2011 Other Health Professional Australia
Primary
Concomitant
Gait Disturbance Other Serious 11/30/2010 5 Female 24 lb 2/24/2011 Physician Japan
Primary
Concomitant
Shock Haemorrhagic Life Threatening 5/24/2010 73 Male 115 lb 3/15/2011 Physician Japan
Primary
Concomitant
Circulatory Collapse Life Threatening 5/24/2010 73 Male 115 lb 3/18/2011 Physician Japan
Primary
Concomitant
Shock Haemorrhagic Life Threatening 5/24/2010 73 Male 115 lb 3/23/2011 Physician Japan
Primary
Concomitant
Pulmonary Hypertension Life Threatening 11/16/2010 15 Male 68 lb 3/30/2011 Physician Japan
Primary
Concomitant
Death Death 12/1/2010 76 Male 138 lb 4/18/2011 Physician Japan
Primary
Concomitant
Cyanosis Hospitalization 1/28/2010 Female 11 lb 4/26/2011 Physician Philippines
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 7/29/2010 71 Female 84 lb 5/17/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 5/13/2011 5/24/2011 Pharmacist United States
Primary
Concomitant
Umbilical Hernia, Obstructive Death 12/24/2010 76 Male 138 lb 5/27/2011 Physician Japan
Primary
Concomitant
Respiratory Distress Hospitalization 1/28/2010 Female 11 lb 5/31/2011 Consumer Philippines
Primary
Concomitant
Death Hospitalization 5/27/2010 57 Female 126 lb 5/30/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Death 11/20/2010 15 Male 68 lb 6/3/2011 Physician Japan
Primary
Concomitant
Tachycardia Hospitalization 7/29/2010 71 Female 84 lb 6/6/2011 Physician Japan
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 5/1/2011 6/10/2011 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 11/1/2009 1 Female 15 lb 6/29/2011 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 5/13/2011 6/29/2011 Physician United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 11/1/2009 1 Female 15 lb 7/8/2011 Physician Japan
Primary
Concomitant
Pulmonary Hypertension Hospitalization 5/27/2010 57 Female 126 lb 7/21/2011 Physician Japan
Primary
Concomitant
Scar Other Serious 3/1/2007 55 Male 291 lb 8/1/2011 Lawyer United States
Primary
Secondary
Concomitant
Labyrinthitis Other Serious 70 Female 9/1/2011 Physician Canada
Primary
Concomitant
Flushing Other Serious 9/19/2011 9/29/2011 Physician United States
Primary
Concomitant
Diarrhoea Other Serious 9/19/2011 10/5/2011 Physician United States
Primary
Concomitant
Constipation Hospitalization 9/18/2011 52 Female 201 lb 10/18/2011 Physician Germany
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 5/28/2011 Female 10/31/2011 Physician Germany
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 1/10/2011 78 Female 100 lb 11/22/2011 Physician Japan
Primary
Concomitant
Anaemia Hospitalization 4/9/2009 60 Female 108 lb 12/5/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 10/8/2011 2 Female 23 lb 12/29/2011 Physician Japan
Primary
Concomitant
Urine Output Decreased Other Serious 1/10/2011 78 Female 100 lb 12/30/2011 Physician Japan
Primary
Secondary
Concomitant
Headache Hospitalization 6/13/2009 10 Female 48 lb 12/30/2011 Physician Japan
Primary
Concomitant

Drug Data