Aldactone combined with Nexavar

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Nausea Hospitalization 3/28/2007 63 Male 192 lb 4/19/2007 Physician France
Primary
Concomitant
Rash Generalised Other Serious 2/1/2007 62 Female 4/27/2007 Other Health Professional United States
Primary
Concomitant
Rash Generalised Other Serious 2/1/2007 62 Female 6/21/2007 Other Health Professional United States
Primary
Concomitant
Hepatic Failure Hospitalization 4/6/2007 77 Female 7/9/2007 Physician Spain
Primary
Concomitant
Hepatic Failure Hospitalization 4/6/2007 77 Female 7/18/2007 Physician Spain
Primary
Concomitant
Thrombocytopenia Other Serious 7/8/2007 75 Male 8/7/2007 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/8/2007 75 Male 10/5/2007 Physician United States
Primary
Concomitant
Renal Failure Other Serious 5/6/2008 63 Male 128 lb 6/24/2008 Consumer Egypt
Primary
Concomitant
Hepatic Failure Hospitalization 10/9/2008 69 Male 10/31/2008 Physician Austria
Primary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 5/21/2008 64 Female 97 lb 12/9/2008 Physician Japan
Primary
Concomitant
Cardiac Disorder Death Male 159 lb 1/27/2009 Germany
Primary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 5/21/2008 64 Female 97 lb 2/2/2009 Physician Japan
Primary
Concomitant
Cardiac Disorder Death Male 159 lb 2/11/2009 Germany
Primary
Concomitant
Death Death 1/19/2009 74 Male 159 lb 2/16/2009 Germany
Primary
Concomitant
Angioedema Hospitalization 8/10/2008 68 Male 3/3/2009 Physician Germany
Primary
Secondary
Concomitant
Angioedema Hospitalization 8/10/2008 68 Male 3/10/2009 Other Health Professional
Primary
Secondary
Concomitant
Sepsis Death 1/19/2009 74 Male 159 lb 4/3/2009 Germany
Primary
Concomitant
Hepatic Encephalopathy Other Serious 7/25/2008 72 Male 179 lb 4/8/2009 Physician Japan
Primary
Concomitant
Skin Exfoliation Other Serious 2/9/2009 56 Male 5/5/2009 United States
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 1/1/2009 57 Male 5/11/2009 Physician United States
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 4/26/2009 57 Male 5/29/2009 Physician United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 6/23/2008 76 Male 101 lb 6/12/2009 Physician Japan
Primary
Concomitant
Confusional State Hospitalization 6/1/2009 66 Male 6/26/2009 Netherlands
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 4/26/2009 57 Male 7/1/2009 Physician United States
Primary
Concomitant
Lung Disorder Life Threatening 7/11/2009 80 Female 7/17/2009 Physician Japan
Primary
Concomitant
Acute Respiratory Distress Syndrome Death 7/11/2009 81 Female 7/27/2009 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 6/5/2009 80 Male 8/11/2009 Physician Japan
Primary
Concomitant
Cardiac Failure Death 6/27/2009 52 Female 88 lb 8/11/2009 Physician Japan
Primary
Concomitant
Sinus Bradycardia Life Threatening 6/23/2009 69 Male 157 lb 8/14/2009 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 7/14/2009 79 Male 163 lb 8/17/2009 Physician Japan
Primary
Concomitant
Hepatic Failure Life Threatening 6/26/2009 77 Male 115 lb 8/18/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 6/26/2009 58 Male 143 lb 8/20/2009 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Death 8/6/2009 67 Male 121 lb 8/24/2009 Physician Japan
Primary
Concomitant
Nausea Death 7/30/2009 80 Male 97 lb 8/27/2009 Physician Japan
Primary
Concomitant
Neoplasm Progression Other Serious 1/1/2009 66 Male 8/27/2009 Netherlands
Primary
Secondary
Concomitant
Insomnia Life Threatening 7/10/2009 81 Female 115 lb 8/31/2009 Physician Japan
Primary
Concomitant
Renal Failure Life Threatening 7/13/2009 66 Female 106 lb 9/3/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 5/11/2009 44 Male 176 lb 9/8/2009 Other Health Professional United States
Primary
Concomitant
Liver Disorder Life Threatening 7/6/2009 48 Male 170 lb 9/8/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/29/2009 72 Male 130 lb 9/9/2009 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 8/21/2009 80 Female 9/9/2009 Physician Japan
Primary
Concomitant
Hepatic Failure Life Threatening 6/26/2009 77 Male 115 lb 9/9/2009 Physician Japan
Primary
Concomitant
Supraventricular Tachycardia Other Serious 5/22/2009 59 Male 134 lb 9/10/2009 Physician Japan
Primary
Concomitant
Hypophosphataemia Hospitalization 7/27/2009 73 Male 132 lb 9/11/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2009 79 Female 9/16/2009 Physician Japan
Primary
Concomitant
Rash Hospitalization 7/1/2009 66 Male 117 lb 9/17/2009 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 7/3/2009 72 Male 104 lb 9/18/2009 Physician Japan
Primary
Concomitant
Malaise Hospitalization 8/19/2009 56 Male 168 lb 9/21/2009 Physician Japan
Primary
Concomitant
Rash Generalised Life Threatening 8/18/2009 54 Male 119 lb 9/24/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 8/11/2009 61 Male 161 lb 10/2/2009 Physician Japan
Primary
Concomitant
Supraventricular Tachycardia Other Serious 5/22/2009 59 Male 134 lb 10/2/2009 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 6/5/2009 80 Male 10/5/2009 Physician Japan
Primary
Concomitant
Rash Hospitalization 7/1/2009 66 Male 117 lb 10/6/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/19/2009 69 Male 168 lb 10/7/2009 Physician Japan
Primary
Concomitant
Shock Death 9/1/2009 73 Male 97 lb 10/9/2009 Physician Japan
Primary
Concomitant
Liver Disorder Life Threatening 8/14/2009 60 Female 110 lb 10/9/2009 Physician Japan
Primary
Concomitant
Pancreatitis Hospitalization 8/31/2009 58 Male 130 lb 10/9/2009 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 6/1/2009 52 Male 10/13/2009 United States
Primary
Concomitant
Rash Other Serious 6/6/2009 46 Male 152 lb 10/14/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 6/26/2009 58 Male 143 lb 10/16/2009 Physician Japan
Primary
Concomitant
Monoplegia Disability 8/21/2009 62 Male 10/16/2009 Physician Japan
Primary
Concomitant
Rash Hospitalization 7/1/2009 66 Male 117 lb 10/16/2009 Physician Japan
Primary
Concomitant
Shock Death 9/1/2009 73 Male 97 lb 10/19/2009 Physician Japan
Primary
Concomitant
Shock Haemorrhagic Death 9/1/2009 73 Male 97 lb 10/20/2009 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Hospitalization 6/23/2008 76 Male 101 lb 10/21/2009 Physician Japan
Primary
Concomitant
Liver Disorder Life Threatening 8/14/2009 60 Female 110 lb 10/23/2009 Physician Japan
Primary
Concomitant
Nausea Life Threatening 7/30/2009 80 Male 97 lb 10/28/2009 Physician Japan
Primary
Concomitant
Pancreatitis Hospitalization 8/31/2009 58 Male 130 lb 10/29/2009 Physician Japan
Primary
Concomitant
Rash Death 8/4/2009 76 Male 121 lb 10/29/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/14/2009 54 Male 176 lb 10/30/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/2/2009 74 Female 10/30/2009 Physician Japan
Primary
Concomitant
Rash Life Threatening 8/18/2009 54 Male 119 lb 11/5/2009 Physician Japan
Primary
Concomitant
Rash Hospitalization 7/3/2009 77 Male 121 lb 11/5/2009 Physician Japan
Primary
Concomitant
Sinus Bradycardia Life Threatening 6/9/2009 69 Male 157 lb 11/9/2009 Physician Japan
Primary
Concomitant
Hyperammonaemia Disability 9/8/2009 60 Male 119 lb 11/11/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 8/11/2009 61 Male 161 lb 11/12/2009 Physician Japan
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 10/1/2009 62 Male 229 lb 11/18/2009 Physician United States
Primary
Concomitant
Pyrexia Other Serious 1/1/2009 66 Female 121 lb 11/20/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/29/2009 72 Male 130 lb 11/23/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/10/2009 80 Male 128 lb 11/24/2009 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 6/24/2009 78 Male 121 lb 11/25/2009 Physician Japan
Primary
Concomitant
Shock Haemorrhagic Death 8/2/2009 63 Male 134 lb 11/27/2009 Japan
Primary
Concomitant
Peritonitis Bacterial Hospitalization 6/19/2009 78 Female 121 lb 11/30/2009 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 7/14/2009 79 Male 163 lb 11/30/2009 Physician Japan
Primary
Concomitant
Pancreatitis Hospitalization 8/31/2009 58 Male 130 lb 12/1/2009 Physician Japan
Primary
Concomitant
Hyperammonaemia Disability 9/8/2009 60 Male 119 lb 12/1/2009 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 11/23/2009 79 Male 12/1/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/10/2009 80 Male 128 lb 12/2/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/28/2009 73 Female 117 lb 12/3/2009 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 7/14/2009 79 Male 163 lb 12/8/2009 Physician Japan
Primary
Concomitant
Sinus Bradycardia Life Threatening 6/9/2009 69 Male 157 lb 12/10/2009 Physician Japan
Primary
Concomitant
Oesophageal Ulcer Life Threatening 5/28/2008 78 Male 12/11/2009 Consumer France
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Death 10/9/2009 88 Male 130 lb 12/14/2009 Physician Japan
Primary
Concomitant
Monoplegia Disability 8/21/2009 62 Male 12/14/2009 Physician Japan
Primary
Concomitant
Splenomegaly Other Serious 6/1/2009 55 Male 12/15/2009 Physician United States
Primary
Concomitant
Shock Haemorrhagic Death 8/2/2009 63 Male 134 lb 12/18/2009 Pharmacist Japan
Primary
Concomitant
Rash Other Serious 7/2/2009 66 Female 112 lb 12/18/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/1/2009 67 Female 123 lb 12/18/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 1/13/2009 74 Male 12/22/2009 Consumer France
Primary
Concomitant
Renal Failure Acute Hospitalization 11/9/2009 71 Male 12/22/2009 Physician Japan
Primary
Secondary
Tumour Lysis Syndrome Hospitalization 8/20/2009 80 Female 75 lb 12/28/2009 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 10/8/2009 71 Male 117 lb 12/28/2009 Physician Japan
Primary
Concomitant
Confusional State Hospitalization 5/27/2009 55 Male 12/28/2009 Consumer France
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/31/2009 62 Female 128 lb 12/29/2009 Physician Japan
Primary
Concomitant
Pain Other Serious 11/16/2009 74 Male 152 lb 12/29/2009 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 11/18/2009 81 Female 95 lb 12/29/2009 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 11/18/2009 81 Female 95 lb 1/4/2010 Physician Japan
Primary
Secondary
Concomitant
Oesophageal Ulcer Life Threatening 5/28/2008 78 Male 1/6/2010 Consumer France
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Death 10/9/2009 88 Male 130 lb 1/6/2010 Physician Japan
Primary
Concomitant
Oesophageal Ulcer Life Threatening 5/28/2008 78 Male 1/7/2010 Consumer France
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/14/2009 79 Male 163 lb 1/7/2010 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 7/14/2009 79 Male 163 lb 1/8/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/3/2009 46 Male 152 lb 1/8/2010 Physician Japan
Primary
Concomitant
Hepatic Failure Death 12/18/2009 64 Male 1/8/2010 Physician Japan
Primary
Concomitant
Liver Carcinoma Ruptured Life Threatening 9/11/2009 72 Male 132 lb 1/8/2010 Physician Japan
Primary
Concomitant
Transaminases Increased Hospitalization 12/13/2009 71 Male 1/8/2010 Physician Italy
Primary
Concomitant
Transaminases Increased Hospitalization 12/13/2009 71 Male 1/11/2010 Physician Italy
Primary
Concomitant
Vomiting Other Serious 12/18/2009 64 Male 1/18/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 11/23/2009 62 Male 126 lb 1/19/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/18/2009 64 Male 1/19/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/2/2009 74 Female 1/20/2010 Physician Japan
Primary
Concomitant
Skin Hypertrophy Other Serious 7/30/2009 54 Male 198 lb 1/25/2010 Physician Japan
Primary
Concomitant
Hepatic Failure Death 11/21/2009 71 Male 1/25/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/18/2009 64 Male 1/25/2010 Physician Japan
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 7/10/2009 81 Female 115 lb 1/28/2010 Other Health Professional Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 11/9/2009 71 Male 2/1/2010 Physician Japan
Primary
Secondary
Interstitial Lung Disease Life Threatening 11/18/2009 81 Female 95 lb 2/1/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 11/19/2009 79 Male 172 lb 2/2/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Death 10/14/2009 69 Male 143 lb 2/2/2010 Physician Japan
Primary
Concomitant
Hyperammonaemia Death 12/24/2009 69 Male 2/4/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 1/10/2010 74 Female 106 lb 2/4/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 6/17/2009 62 Male 143 lb 2/8/2010 Physician Japan
Primary
Concomitant
Urinary Tract Infection Death 11/18/2009 79 Male 119 lb 2/9/2010 Physician Japan
Primary
Concomitant
Hyperammonaemia Death 12/24/2009 69 Male 2/9/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Life Threatening 1/4/2010 65 Male 101 lb 2/11/2010 Physician Japan
Primary
Concomitant
Transaminases Increased Hospitalization 12/13/2009 71 Male 2/11/2010 Physician Italy
Primary
Concomitant
Hepatic Failure Life Threatening 6/26/2009 77 Male 115 lb 2/11/2010 Physician Japan
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 2/11/2010 Physician United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/28/2009 73 Female 117 lb 2/12/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 7/13/2009 56 Male 154 lb 2/12/2010 Physician Japan
Primary
Concomitant
Peritonitis Bacterial Hospitalization 6/19/2009 78 Female 121 lb 2/18/2010 Physician Japan
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 2/18/2010 Physician United States
Primary
Concomitant
Stomatitis Other Serious 7/29/2009 72 Male 130 lb 2/23/2010 Physician Japan
Primary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 7/27/2009 73 Male 132 lb 2/23/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome 1/10/2010 74 Female 106 lb 2/23/2010 Physician Japan
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 2/26/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 3/2/2010 Physician United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 12/17/2009 61 Male 132 lb 3/3/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 7/2/2009 66 Female 112 lb 3/4/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/14/2009 54 Male 176 lb 3/5/2010 Physician Japan
Primary
Concomitant

Drug Data