Aflibercept combined with Docetaxel

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyrexia Hospitalization 7/26/2006 57 Male 176 lb 10/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/26/2006 57 Male 176 lb 11/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 9/19/2006 44 Male 166 lb 11/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 11/2/2007 65 Male 225 lb 11/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 11/2/2007 65 Male 225 lb 11/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 11/2/2007 65 Male 225 lb 1/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Life Threatening 11/2/2007 65 Male 225 lb 2/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Life Threatening 11/2/2007 65 Male 225 lb 2/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 4/10/2008 62 Male 4/21/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Epistaxis Death 4/10/2008 62 Male 6/9/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 9/1/2008 74 Male 115 lb 9/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Cerebrovascular Accident Death 11/4/2008 77 Male 11/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 11/14/2008 72 Male 141 lb 11/24/2008 Other Health Professional Germany
Primary
Secondary
Small Intestinal Perforation Death 11/14/2008 72 Male 141 lb 12/3/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Peripheral Ischaemia Hospitalization 11/18/2008 65 Male 181 lb 12/11/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 11/25/2008 73 Male 161 lb 12/22/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Peripheral Ischaemia Hospitalization 11/18/2008 65 Male 181 lb 12/22/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Syncope Life Threatening 11/2/2007 65 Male 225 lb 1/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vaginal Fistula Other Serious 6/10/2008 48 Female 187 lb 1/15/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 11/25/2008 73 Male 161 lb 1/29/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Cerebrovascular Accident Death 11/4/2008 77 Male 150 lb 2/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Intestinal Perforation Other Serious 11/4/2008 77 Male 150 lb 2/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Intestinal Perforation Other Serious 11/4/2008 77 Male 150 lb 2/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 1/12/2009 82 Male 140 lb 3/17/2009 Other Health Professional Chile
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 1/12/2009 82 Male 140 lb 3/17/2009 Other Health Professional Chile
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 1/24/2009 50 Male 161 lb 3/23/2009 Other Health Professional France
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 12/12/2008 70 Male 171 lb 3/31/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 12/12/2008 70 Male 171 lb 4/6/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombosis Death 4/12/2009 66 Male 251 lb 4/20/2009 Other Health Professional Argentina
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/21/2006 74 Male 175 lb 4/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 11/3/2008 51 Female 134 lb 4/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombosis Death 4/12/2009 66 Male 251 lb 5/4/2009 Other Health Professional Argentina
Primary
Secondary
Concomitant
Thrombosis Hospitalization 4/12/2009 66 Male 251 lb 5/6/2009 Other Health Professional Argentina
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 9/1/2008 74 Male 115 lb 5/13/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Necrotising Hospitalization 5/13/2009 59 Male 135 lb 5/27/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Pneumonia Necrotising Hospitalization 6/22/2008 71 Female 117 lb 5/27/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Pigmentary Glaucoma Other Serious 12/12/2008 61 Male 149 lb 6/1/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Supraventricular Tachycardia Death 5/29/2009 70 Male 6/8/2009 Other Health Professional Turkey
Primary
Secondary
Concomitant
Pneumonia Necrotising Hospitalization 5/13/2009 59 Male 135 lb 6/15/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Supraventricular Tachycardia Death 5/29/2009 70 Male 6/19/2009 Other Health Professional Turkey
Primary
Secondary
Concomitant
Pneumonia Necrotising Hospitalization 5/13/2009 59 Male 135 lb 6/22/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Infarction Hospitalization 5/15/2009 67 Male 129 lb 6/23/2009 Other Health Professional Singapore
Primary
Secondary
Concomitant
Infarction Hospitalization 5/15/2009 67 Male 129 lb 6/25/2009 Other Health Professional Singapore
Primary
Secondary
Concomitant
Pneumonia Necrotising Hospitalization 5/13/2009 59 Male 135 lb 6/25/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 9/1/2008 74 Male 115 lb 7/24/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Corneal Erosion Other Serious 7/6/2009 80 Male 168 lb 8/3/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/21/2006 74 Male 175 lb 8/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Proteinuria Other Serious 6/30/2009 80 Male 168 lb 8/25/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 7/13/2009 79 Male 151 lb 8/28/2009 Other Health Professional South Africa
Primary
Secondary
Concomitant
Pigmentary Glaucoma Other Serious 12/12/2008 61 Male 149 lb 8/31/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 7/13/2009 79 Male 151 lb 9/1/2009 Other Health Professional South Africa
Primary
Secondary
Concomitant
Vaginal Fistula Other Serious 6/10/2008 48 Female 187 lb 9/2/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pyrexia Death 1/24/2009 50 Male 161 lb 9/8/2009 Other Health Professional France
Primary
Secondary
Concomitant
Urethral Stenosis Hospitalization 79 Male 151 lb 9/11/2009 Other Health Professional South Africa
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 9/13/2009 74 Male 185 lb 9/21/2009 Other Health Professional United States
Primary
Secondary
Chest Pain Hospitalization 4/14/2008 75 Male 182 lb 10/2/2009 Other Health Professional Hungary
Primary
Secondary
Concomitant
Pneumonia Aspiration Life Threatening 9/13/2009 74 Male 185 lb 10/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Death 9/2/2009 62 Male 175 lb 10/14/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Sudden Death Death 9/2/2009 62 Male 175 lb 10/26/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Haemangioma Other Serious 8/23/2009 66 Male 160 lb 11/5/2009 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization 11/14/2008 72 Male 141 lb 11/17/2009 Consumer Germany
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/14/2009 63 Male 11/25/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 10/28/2009 43 Male 12/3/2009 Physician Turkey
Primary
Secondary
Concomitant
Lung Disorder Hospitalization 10/20/2009 69 Male 174 lb 12/4/2009 Physician Chile
Primary
Secondary
Concomitant
Death Death 11/6/2009 75 Male 150 lb 12/8/2009 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/14/2009 63 Male 244 lb 12/22/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Cholecystitis Acute Hospitalization 12/4/2009 66 Male 220 lb 12/22/2009 Physician Italy
Primary
Secondary
Concomitant
Haemangioma Other Serious 8/23/2009 66 Male 160 lb 12/22/2009 Consumer Korea, Republic Of
Primary
Secondary
Concomitant
Dehydration Hospitalization 12/15/2009 66 Male 202 lb 12/24/2009 Physician South Africa
Primary
Secondary
Concomitant
Haemangioma Other Serious 8/23/2009 66 Male 160 lb 1/4/2010 Consumer Korea, Republic Of
Primary
Secondary
Concomitant
Cholecystitis Acute Hospitalization 12/4/2009 66 Male 220 lb 1/4/2010 Physician Italy
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/18/2009 71 Female 112 lb 1/4/2010 Physician France
Primary
Secondary
Concomitant
Peripheral Ischaemia Hospitalization 11/18/2008 65 Male 181 lb 1/5/2010 Consumer Spain
Primary
Secondary
Concomitant
Dehydration Hospitalization 12/15/2009 66 Male 202 lb 1/8/2010 Physician South Africa
Primary
Secondary
Concomitant
Cholecystitis Acute Hospitalization 12/4/2009 66 Male 220 lb 1/11/2010 Physician Italy
Primary
Secondary
Concomitant
Proteinuria Other Serious 6/20/2009 80 Male 168 lb 1/11/2010 Consumer Sweden
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 10/27/2008 51 Female 134 lb 2/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 6/27/2008 61 Male 198 lb 2/11/2010 Consumer France
Primary
Secondary
Concomitant
Hepatomegaly Hospitalization 1/14/2010 66 Male 148 lb 2/16/2010 Physician Turkey
Primary
Secondary
Concomitant
Sudden Death Death 9/2/2009 62 Male 175 lb 2/19/2010 Consumer Denmark
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 1/21/2010 71 Male 2/22/2010 Physician Australia
Primary
Secondary
Concomitant
Impaired Healing Other Serious 43 Male 2/23/2010 France
Primary
Secondary
Febrile Neutropenia Death 2/8/2010 75 Male 146 lb 2/24/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Death Death 5/29/2009 70 Male 2/25/2010 Consumer Turkey
Primary
Secondary
Concomitant
Death Death 5/29/2009 70 Male 3/1/2010 Consumer Turkey
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 2/17/2010 47 Male 146 lb 3/2/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Febrile Neutropenia Death 2/8/2010 75 Male 146 lb 3/4/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Vomiting Life Threatening 11/6/2009 75 Male 150 lb 3/8/2010 Physician United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 2/17/2010 47 Male 146 lb 3/10/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Hypertension Life Threatening 3/5/2010 78 Male 163 lb 3/19/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 2/17/2010 47 Male 146 lb 3/24/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Hypertension Other Serious 3/5/2010 78 Male 163 lb 3/31/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Haemorrhagic Stroke Other Serious 3/5/2010 78 Male 163 lb 4/6/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Proteinuria Other Serious 6/20/2009 80 Male 168 lb 4/8/2010 Consumer Sweden
Primary
Secondary
Concomitant
Malaise Hospitalization 2/7/2010 77 Male 192 lb 4/9/2010 Physician Netherlands
Primary
Secondary
Concomitant
Hypertensive Crisis Hospitalization 1/13/2010 78 Male 132 lb 4/20/2010 Physician Hungary
Primary
Secondary
Concomitant
Malaise Hospitalization 2/7/2010 77 Male 192 lb 4/21/2010 Physician Netherlands
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 1/21/2010 71 Male 4/22/2010 Physician Australia
Primary
Secondary
Concomitant
Hypotension Life Threatening 11/6/2009 75 Male 150 lb 4/23/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/20/2009 69 Male 174 lb 4/26/2010 Physician Chile
Primary
Secondary
Concomitant
Urethral Stenosis Hospitalization 11/14/2009 79 Male 150 lb 4/26/2010 Physician South Africa
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 1/15/2010 76 Male 192 lb 4/27/2010 Physician United States
Primary
Secondary
Concomitant
Malaise Hospitalization 2/7/2010 77 Male 192 lb 4/27/2010 Physician Netherlands
Primary
Secondary
Concomitant
Death Death 3/11/2010 77 Male 134 lb 4/30/2010 Physician Chile
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 1/21/2010 71 Male 5/4/2010 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/16/2010 77 Male 186 lb 5/6/2010 Physician Netherlands
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/13/2010 78 Male 132 lb 5/7/2010 Physician Hungary
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 2/9/2010 78 Male 119 lb 5/10/2010 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Urethral Stenosis Hospitalization 11/14/2009 79 Male 150 lb 5/12/2010 Physician South Africa
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/13/2010 78 Male 132 lb 5/17/2010 Physician Hungary
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 2/17/2010 47 Male 146 lb 5/17/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 4/22/2010 51 Male 132 lb 5/17/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/14/2009 67 Male 244 lb 5/26/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 4/22/2010 51 Male 132 lb 5/27/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/16/2010 77 Male 186 lb 6/1/2010 Physician Netherlands
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 1/21/2010 71 Male 6/4/2010 Physician Australia
Primary
Secondary
Concomitant
Death Death 4/1/2010 43 Male 157 lb 6/7/2010 Physician Brazil
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 9/1/2008 74 Male 115 lb 6/8/2010 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 1/15/2010 76 Male 192 lb 6/8/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/16/2010 77 Male 186 lb 6/9/2010 Physician Netherlands
Primary
Secondary
Concomitant
Infection Hospitalization 1/15/2010 60 Female 168 lb 6/11/2010 Physician United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 2/17/2010 47 Male 146 lb 6/15/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 2/17/2010 47 Male 146 lb 7/1/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Malaise Other Serious 2/7/2010 77 Male 192 lb 7/1/2010 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 3/16/2010 77 Male 186 lb 7/1/2010 Physician Netherlands
Primary
Secondary
Concomitant
Restrictive Cardiomyopathy Hospitalization 10/20/2009 69 Male 174 lb 7/9/2010 Physician Chile
Primary
Secondary
Concomitant
Autoimmune Thrombocytopenia Life Threatening 3/10/2008 72 Male 231 lb 7/12/2010 Consumer Czech Republic
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 2/9/2010 78 Male 119 lb 7/12/2010 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/14/2009 67 Male 244 lb 7/15/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 9/1/2008 74 Male 115 lb 7/19/2010 Physician Japan
Primary
Secondary
Concomitant
Supraventricular Tachycardia Life Threatening 5/29/2009 70 Male 7/29/2010 Consumer Turkey
Primary
Secondary
Concomitant
Pneumonia Necrotising Hospitalization 5/25/2010 66 Male 182 lb 8/10/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 2/17/2010 47 Male 146 lb 8/12/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 2/9/2010 78 Male 119 lb 8/23/2010 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Hypotension Life Threatening 11/6/2009 75 Male 150 lb 8/25/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/16/2010 77 Male 186 lb 8/30/2010 Physician Netherlands
Primary
Secondary
Concomitant
Pneumonia Necrotising Hospitalization 5/25/2010 66 Male 182 lb 8/30/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Disease Progression Death 3/11/2010 77 Male 134 lb 9/3/2010 Physician Chile
Primary
Secondary
Concomitant
Pigmentary Glaucoma Other Serious 12/12/2008 61 Male 149 lb 9/6/2010 Consumer Canada
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 2/9/2010 78 Male 119 lb 9/6/2010 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Pigmentary Glaucoma Other Serious 12/12/2008 61 Male 149 lb 9/7/2010 Consumer Canada
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 2/7/2010 77 Male 192 lb 9/10/2010 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 3/16/2010 77 Male 186 lb 9/13/2010 Physician Netherlands
Primary
Secondary
Concomitant
Death Hospitalization 4/14/2008 75 Male 182 lb 9/22/2010 Consumer Hungary
Primary
Secondary
Concomitant
Pneumonia Necrotising Hospitalization 5/25/2010 66 Male 182 lb 9/30/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 11/6/2009 75 Male 150 lb 10/1/2010 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/14/2009 67 Male 244 lb 10/1/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Dermatitis Bullous Other Serious 2/24/2009 75 Male 195 lb 10/1/2010 Physician Brazil
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization 11/14/2008 72 Male 141 lb 10/6/2010 Consumer Germany
Primary
Secondary
Concomitant
Venous Thrombosis Limb Hospitalization 4/12/2009 66 Male 251 lb 10/7/2010 Physician Argentina
Primary
Secondary
Concomitant

Drug Data