Adriacin combined with Endoxan

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Red Blood Cell Count Decreased Other Serious 9/2/2005 23 Male 1/6/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Life Threatening 4/18/2005 10 Female 1/18/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Tumour Ulceration Other Serious 8/8/2005 60 Female 130 lb 3/4/2006 Physician Japan
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 7/14/2005 64 Female 3/14/2006 Physician Japan
Primary
Concomitant
Precursor T-lymphoblastic Lymphoma/leukaemia Other Serious 10 Female 3/14/2006 Consumer United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 4/1/2005 76 Male 3/18/2006 Pharmacist Japan
Primary
Concomitant
Treatment Related Secondary Malignancy Other Serious 1/1/2004 64 Male 3/23/2006 Consumer United States
Primary
Concomitant
Treatment Related Secondary Malignancy Death 2/9/2000 62 Male 3/24/2006 Consumer United States
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Death 5/21/2003 36 Male 3/24/2006 Consumer United States
Primary
Secondary
Concomitant
Cardiomyopathy Death 48 Male 3/24/2006 Consumer United States
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Death 3/1/2005 42 Female 3/28/2006 Consumer United States
Primary
Concomitant
Hepatic Neoplasm Malignant Recurrent Hospitalization 7/14/2005 64 Female 4/4/2006 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Recurrent Hospitalization 7/14/2005 64 Female 4/13/2006 Physician Japan
Primary
Concomitant
Chronic Eosinophilic Leukaemia Hospitalization 12/1/2000 43 Male 5/5/2006 Consumer United States
Primary
Secondary
Concomitant
Chronic Eosinophilic Leukaemia Hospitalization 12/1/2000 43 Male 5/12/2006 Consumer United States
Primary
Secondary
Concomitant
Hepatitis Hospitalization 70 Female 5/16/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 8/31/2001 48 Male 6/1/2006 Consumer United States
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Life Threatening 5/11/2005 56 Male 6/1/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 11/29/2005 72 Female 6/20/2006 Physician Japan
Primary
Concomitant
Treatment Related Secondary Malignancy Life Threatening 5/11/2005 56 Male 7/7/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 7/20/2007 68 Female 104 lb 11/2/2007 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 1/1/2007 28 Female 11/5/2007 Consumer United States
Primary
Secondary
Toothache Other Serious 11/1/2006 65 Female 108 lb 11/14/2007 Japan
Primary
Secondary
Concomitant
Acute Lymphocytic Leukaemia Other Serious 12/22/2005 4 Male 11/19/2007 Consumer Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 9/4/2007 65 Male 11/19/2007 Physician Japan
Primary
Secondary
Clostridium Difficile Colitis Death 70 Female 11/19/2007 Japan
Primary
Secondary
Hepatitis C Hospitalization 7/4/2007 Female 107 lb 2/28/2008 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 9/4/2007 Male 110 lb 2/29/2008 Physician Japan
Primary
Secondary
Concomitant
Myalgia Other Serious 5/25/2007 Female 141 lb 5/2/2008 Physician Japan
Primary
Concomitant
Interacting
Myalgia Other Serious 6/23/2007 Female 112 lb 5/2/2008 Physician Japan
Primary
Concomitant
Interacting
Neuropathy Peripheral Other Serious 7/17/2007 Male 152 lb 5/2/2008 Physician Japan
Primary
Concomitant
Interacting
Tumour Lysis Syndrome Life Threatening 1/1/1997 27 Male 5/6/2008 Consumer United States
Primary
Secondary
Pancytopenia Hospitalization 5/22/2007 49 Female 5/14/2008 Japan
Primary
Secondary
Multi-organ Failure Hospitalization 2/1/2005 32 Male 5/27/2008 Consumer United States
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 3/1/2006 32 Male 5/27/2008 Consumer United States
Primary
Secondary
Concomitant
Toothache Other Serious 11/1/2006 Female 108 lb 6/4/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening Male 6/21/2008 Physician Japan
Primary
Concomitant
Aids Encephalopathy Disability 1/22/2008 35 Male 7/7/2008 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/8/2008 Male 110 lb 7/8/2008 Physician Japan
Primary
Secondary
Concomitant
Aids Encephalopathy Disability 1/22/2008 35 Male 8/5/2008 Other Health Professional Japan
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 4/7/2008 34 Male 172 lb 9/2/2008 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 7/12/2005 78 Female 112 lb 10/8/2008 Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Death 21 Male 10/28/2008 Other Health Professional Japan
Primary
Concomitant
Diabetes Insipidus Other Serious 5/30/2008 Male 117 lb 11/5/2008 Physician Japan
Primary
Concomitant
Bone Sarcoma Other Serious 10/1/2007 12 Male 11/7/2008 Japan
Primary
Secondary
Tooth Extraction Other Serious 3/1/2008 Female 104 lb 11/11/2008 Physician Japan
Primary
Secondary
Concomitant
Protein Urine Present Other Serious 12/17/2007 Male 11/20/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonitis Other Serious 12/12/2008 Other Health Professional
Primary
Secondary
Tooth Extraction Other Serious 3/1/2008 Female 104 lb 12/17/2008 Physician Japan
Primary
Secondary
Concomitant
Protein Urine Present Other Serious 12/17/2007 Male 12/17/2008 Physician Japan
Primary
Secondary
Concomitant
Diabetes Insipidus Other Serious 5/30/2008 Male 117 lb 12/22/2008 Physician Japan
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 10/22/2006 Female 12/24/2008 Physician Japan
Primary
Secondary
Concomitant
Protein Urine Present Other Serious 12/17/2007 Male 1/8/2009 Physician Japan
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 10/22/2006 Female 1/30/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumonitis Other Serious 6/19/2007 2/9/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Cerebral Infarction Life Threatening 11/21/2008 46 Female 90 lb 2/19/2009 Other Health Professional Japan
Primary
Concomitant
Gamma-glutamyltransferase Increased Death 12/19/2008 Female 88 lb 2/24/2009 Physician Japan
Primary
Secondary
Concomitant
Convulsion Hospitalization 12/24/2008 Female 2/25/2009 Physician Japan
Primary
Concomitant
Bone Marrow Failure Death 1/22/2007 Male 3/4/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Death 12/19/2008 Female 88 lb 3/10/2009 Physician Japan
Primary
Secondary
Concomitant
Bone Marrow Failure Death 1/22/2007 3/12/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatitis B Death 4/28/2009 Other Health Professional Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 11/4/2008 55 Female 119 lb 4/29/2009 Pharmacist Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 10/22/2008 Male 5/1/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 5/23/2008 Female 95 lb 5/11/2009 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/23/2008 Female 95 lb 5/20/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Life Threatening 10/17/2008 Female 5/26/2009 Other Health Professional Japan
Primary
Concomitant
Cardiac Failure Other Serious 5/1/2009 43 Male 5/29/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/13/2009 43 Male 6/23/2009 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 5/13/2009 Female 121 lb 7/13/2009 Physician Japan
Primary
Concomitant
Vomiting Other Serious 21 Male 7/13/2009 Other Health Professional Japan
Primary
Concomitant
Myalgia Other Serious 6/23/2007 Female 112 lb 7/22/2009 Other Health Professional Japan
Primary
Concomitant
Interacting
Neoplasm Malignant Death 12/1/2008 60 7/23/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Myalgia Other Serious 7/17/2007 Male 152 lb 7/24/2009 Other Health Professional Japan
Primary
Concomitant
Interacting
Myalgia Other Serious 5/25/2007 Female 141 lb 7/24/2009 Other Health Professional Japan
Primary
Concomitant
Interacting
Myalgia Other Serious 6/3/2007 Female 123 lb 7/24/2009 Other Health Professional Japan
Primary
Concomitant
Interacting
Uterine Leiomyoma Hospitalization 7/21/2009 51 Female 148 lb 7/28/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 21 Male 7/31/2009 Other Health Professional Japan
Primary
Concomitant
Intestinal Obstruction Hospitalization 60 8/5/2009 Other Health Professional Japan
Primary
Secondary
Uterine Leiomyoma Hospitalization 7/21/2009 51 Female 148 lb 8/13/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/26/2009 Male 8/14/2009 Physician Japan
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 68 8/20/2009 Other Health Professional Japan
Primary
Secondary
Sepsis Other Serious 63 8/20/2009 Other Health Professional Japan
Primary
Secondary
Myelodysplastic Syndrome Death 68 9/1/2009 Physician Japan
Primary
Secondary
Bone Marrow Failure Other Serious 63 9/1/2009 Physician Japan
Primary
Secondary
Uterine Leiomyoma Hospitalization 7/21/2009 51 Female 148 lb 9/8/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/13/2009 43 Male 108 lb 9/15/2009 Physician Japan
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 60 9/22/2009 Other Health Professional Japan
Primary
Secondary
Interstitial Lung Disease Other Serious 89 10/7/2009 Other Health Professional Japan
Primary
Secondary
Melaena Other Serious 85 Male 11/4/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Ureteric Cancer Other Serious 64 Male 11/4/2009 Other Health Professional Japan
Primary
Secondary
Neoplasm Malignant Other Serious 82 Male 11/4/2009 Other Health Professional Japan
Primary
Secondary
Neoplasm Malignant Other Serious 70 Male 11/4/2009 Other Health Professional Japan
Primary
Secondary
Neoplasm Malignant Other Serious 49 Male 11/4/2009 Other Health Professional Japan
Primary
Secondary
Neoplasm Malignant Other Serious 49 Male 11/30/2009 Other Health Professional Japan
Primary
Secondary
Ureteric Cancer Other Serious 64 Male 11/30/2009 Other Health Professional Japan
Primary
Secondary
Neoplasm Malignant Other Serious 70 Male 11/30/2009 Other Health Professional Japan
Primary
Secondary
Neoplasm Malignant Other Serious 82 Male 11/30/2009 Other Health Professional Japan
Primary
Secondary
Interstitial Lung Disease Death 8/15/2009 71 Female 157 lb 12/16/2009 Physician Japan
Primary
Concomitant
Pulmonary Embolism Other Serious Male 2/2/2010 Other Health Professional Japan
Primary
Secondary
Peritonitis Life Threatening 10/30/2007 Male 2/2/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 8/15/2009 71 Female 157 lb 2/8/2010 Physician Japan
Primary
Concomitant
Pulmonary Embolism Other Serious Male 2/19/2010 Other Health Professional Japan
Primary
Secondary
Acute Lung Injury Death 9/24/2009 Male 2/25/2010 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Death 10/5/2009 67 Male 3/2/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 4/1/2006 Female 3/2/2010 Consumer Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 8/23/2004 53 Female 3/2/2010 Consumer Japan
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 5/1/2008 44 Female 3/8/2010 Physician Japan
Primary
Secondary
Concomitant
Acute Lung Injury Death 9/24/2009 Male 3/10/2010 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Death 10/5/2009 67 Male 3/12/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Atrioventricular Block Other Serious 1/1/2010 50 Female 110 lb 3/15/2010 Physician Japan
Primary
Secondary
Gamma-glutamyltransferase Increased Death 12/19/2008 81 Female 88 lb 4/26/2010 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 12/3/2008 69 Female 5/3/2010 Other Health Professional Japan
Primary
Concomitant
Cystitis Hospitalization 4/18/2010 40 Female 5/3/2010 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 12/3/2008 69 Female 5/11/2010 Other Health Professional Japan
Primary
Concomitant
Appendicitis Other Serious 42 Female 5/20/2010 Other Health Professional Japan
Primary
Secondary
Appendicitis Other Serious 42 Female 5/31/2010 Other Health Professional Japan
Primary
Secondary
Hepatitis B Disability 8/1/2004 47 Female 6/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Diffuse Large B-cell Lymphoma Stage Iii Life Threatening 7/1/2009 61 Female 137 lb 6/8/2010 Physician Japan
Primary
Secondary
Concomitant
Radial Nerve Palsy Other Serious 5/28/2010 73 Female 6/10/2010 Physician Japan
Primary
Concomitant
Appendicitis Other Serious 42 Female 6/21/2010 Other Health Professional Japan
Primary
Concomitant
Radial Nerve Palsy Other Serious 5/28/2010 73 Female 104 lb 6/29/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/2/2010 33 Female 7/9/2010 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 6/19/2010 52 Female 8/27/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 7/4/2007 61 Female 10/29/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Life Threatening 7/4/2007 61 Female 11/2/2010 Physician Japan
Primary
Secondary
Concomitant
Olfactory Nerve Disorder Disability 11/1/2010 57 Female 11/24/2010 Physician Japan
Primary
Secondary
Olfactory Nerve Disorder Disability 11/1/2010 57 Female 12/31/2010 Physician Japan
Primary
Secondary
Olfactory Nerve Disorder Disability 1/1/2010 57 Female 121 lb 1/6/2011 Physician Japan
Primary
Secondary
Respiratory Failure Other Serious 12/11/2009 56 Female 1/6/2011 Consumer Japan
Primary
Secondary
Pneumonia Hospitalization 1/11/2011 65 Male 1/19/2011 Physician Japan
Primary
Secondary
Pneumonia Hospitalization 1/11/2011 65 Male 1/26/2011 Physician Japan
Primary
Secondary
Febrile Neutropenia Hospitalization 2/12/2011 47 Male 3/1/2011 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 5/13/2009 43 Male 108 lb 3/4/2011 Consumer Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 2/12/2011 47 Male 3/11/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 8/7/2008 58 Male 134 lb 3/16/2011 Physician Japan
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 50 Female 3/25/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 2/14/2011 52 Female 4/1/2011 Other Health Professional Japan
Primary
Concomitant
Pancreatitis Acute Hospitalization 2/14/2011 52 Female 4/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/11/2011 65 Male 4/12/2011 Physician Japan
Primary
Secondary
Pyloric Stenosis Death 3/24/2009 71 Male 4/14/2011 Consumer Japan
Primary
Secondary
Pneumonia Hospitalization 1/11/2011 65 Male 4/21/2011 Physician Japan
Primary
Secondary
Pyloric Stenosis Death 3/24/2009 71 Male 4/21/2011 Consumer Japan
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 50 Female 4/27/2011 Physician Japan
Primary
Secondary
Concomitant
Mucosal Erosion Other Serious 85 Male 11/21/2012 Physician Jp
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 2/10/2011 47 Male 9/11/2012 Physician Jp
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/11/2011 Male 9/4/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Somnolence Other Serious 8/27/2012 53 Female 106 lb 9/14/2012 Physician Jp
Primary
Concomitant
Second Primary Malignancy Hospitalization 8/22/2011 65 Male 121 lb 10/15/2012 Physician Jp
Primary
Secondary
Stomatitis Hospitalization 1/2/2011 66 Male 8/31/2012 Physician Jp
Primary
Secondary
Concomitant

Drug Data