Acyclovir combined with Phenytoin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urine Abnormality Other Serious 9/30/2006 60 Male 10/10/2006 Consumer United States
Primary
Concomitant
Vaginal Cellulitis Required Intervention 11/17/2006 26 Female 1/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/24/2007 30 Male 202 lb 1/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vasculitis Life Threatening 32 Male 8/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hypertension Life Threatening 32 Male 9/11/2007 United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Life Threatening 32 Male 9/28/2007 United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 47 Female 10/4/2007 Other Health Professional Germany
Primary
Concomitant
Nephritis Interstitial Other Serious 40 Male 141 lb 10/27/2007 Pharmacist United States
Primary
Secondary
Concomitant
Nephritis Interstitial Other Serious 40 Male 11/14/2007 Pharmacist United States
Primary
Secondary
Concomitant
Nephritis Interstitial 40 Male 141 lb 11/21/2007 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization Female 1/3/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/13/2007 71 Female 1/14/2008 Physician United States
Primary
Concomitant
Vaginal Candidiasis Hospitalization 11/13/2007 61 Female 170 lb 1/31/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Supraventricular Extrasystoles Required Intervention 3/13/2007 70 Female 1/24/2008 Other Health Professional United States
Primary
Concomitant
Infection Death 2/19/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 1/15/2008 79 Female 220 lb 2/19/2008 Consumer United Kingdom
Primary
Concomitant
Adenocarcinoma Death 2/21/2008 Canada
Primary
Secondary
Concomitant
Sepsis Other Serious 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Sepsis Other Serious 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Sepsis Other Serious 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Other Serious 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Other Serious 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Other Serious 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Death 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Death 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Death 2/22/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Death 2/22/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Arrhythmia Death 2/22/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Death 2/22/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Encephalopathy Death 2/22/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 2/22/2008 Canada
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 2/22/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 1/15/2008 79 Female 220 lb 2/29/2008 Consumer United Kingdom
Primary
Concomitant
Sacroiliitis Other Serious 11/9/2007 42 Male 3/14/2008 Physician Finland
Primary
Concomitant
Neurogenic Bladder Other Serious 9/2/2007 63 Female 117 lb 3/10/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/13/2007 71 Female 3/14/2008 Physician United States
Primary
Concomitant
Pyrexia Other Serious 11 Male 3/25/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 41 Female 4/9/2008 Physician Canada
Primary
Secondary
Concomitant
Skin Test Positive Other Serious 62 Male 4/8/2008 Spain
Primary
Secondary
Concomitant
Wound Infection Hospitalization 4/7/2008 Female 207 lb 4/14/2008 United States
Primary
Concomitant
Neurogenic Bladder Other Serious 9/2/2007 63 Female 117 lb 4/21/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/31/2008 17 Male 121 lb 6/5/2008 Physician United States
Primary
Concomitant
Vulvovaginal Candidiasis Hospitalization 11/13/2007 61 Female 170 lb 7/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urine Ketone Body Present Required Intervention 9/30/2006 60 Male 7/3/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 41 Female 7/7/2008 Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 41 Female 7/17/2008 Canada
Primary
Concomitant
Tremor Other Serious 5/1/2008 Male 7/25/2008 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 6/5/2008 51 Male 7/25/2008 Japan
Primary
Concomitant
Serotonin Syndrome Life Threatening 8/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 2/12/2008 Canada
Primary
Secondary
Concomitant
False Negative Laboratory Result Other Serious 47 Female 10/23/2008 Physician Belgium
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 12/14/2007 Male 52 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Status Epilepticus Required Intervention 3/13/2007 70 Female 11/7/2008 Other Health Professional United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 11/8/2008 18 Female 121 lb 12/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 11/8/2008 18 Female 121 lb 12/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 11/1/2008 18 Female 121 lb 12/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 46 Female 12/4/2008
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 11/8/2008 18 Female 121 lb 12/5/2008 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 11/8/2008 18 Female 12/8/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 11/8/2008 18 Female 12/8/2008 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 11/8/2008 18 Female 12/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 11/8/2008 18 Female 121 lb 12/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 1/2/2008 15 Male 166 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 2/6/2008 14 Female 97 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 6/9/2008 60 Male 249 lb 12/22/2008 Physician United States
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 9/1/2004 59 Female 1/13/2009
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 6/9/2008 60 Male 249 lb 1/13/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 8/29/2008 45 Female 132 lb 1/12/2009 Pharmacist United States
Primary
Concomitant
Status Epilepticus Hospitalization 9/1/2004 59 Female 1/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Intentional Overdose Death 78 Female 2/6/2009 Physician United States
Primary
Concomitant
Pneumonia Death 78 Female 3/23/2009 United States
Primary
Secondary
Concomitant
Drug Toxicity Death 68 Female 3/23/2009 United States
Primary
Secondary
Concomitant
Pneumonia Death 78 Female 4/2/2009 United States
Primary
Secondary
Speech Disorder Death 3 Male 4/15/2009 Consumer Turkey
Primary
Concomitant
Hepatomegaly Other Serious 13 Female 110 lb 5/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 3 Male 5/19/2009 Physician Turkey
Primary
Concomitant
Hepatomegaly Other Serious 13 Female 6/18/2009 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 18 Female 7/2/2009 Pharmacist United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 18 Female 7/24/2009 United States
Primary
Secondary
Concomitant
Urinary Incontinence Death 32 Male 7/31/2009 United Kingdom
Primary
Concomitant
Wound Haemorrhage Death 69 Female 137 lb 8/11/2009 Other Health Professional Netherlands
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 6 Female 9/1/2009 Physician Spain
Primary
Secondary
Respiratory Failure Hospitalization 4/1/2009 17 Female 9/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/1/2009 17 Female 9/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 5/9/1996 Male 9/23/2009 Physician
Primary
Secondary
Respiratory Failure Hospitalization 4/20/2009 17 Female 9/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 5/9/1996 Male 10/7/2009 Physician
Primary
Secondary
Respiratory Failure Hospitalization 4/1/2009 17 Female 10/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/1/2009 17 Female 10/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 4/20/2009 17 Female 11/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Death 78 Female 11/4/2009 Physician United States
Primary
Secondary
Concomitant
Bone Marrow Failure Hospitalization 11/11/2009 60 Female 194 lb 1/5/2010 Pharmacist United States
Primary
Secondary
Nervous System Disorder Other Serious 1/11/2010 Consumer Spain
Primary
Concomitant
Weight Increased Hospitalization Male 1/11/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Male 1/11/2010 Consumer United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 40 Male 141 lb 3/18/2010 Pharmacist United States
Primary
Concomitant
Respiratory Tract Inflammation Other Serious 4/1/2010 64 Male 6/28/2010 Physician United States
Primary
Concomitant
Respiratory Tract Inflammation Other Serious 4/1/2010 64 Male 7/7/2010 Physician United States
Primary
Concomitant
Respiratory Tract Inflammation Other Serious 4/1/2010 64 Male 7/13/2010 Physician United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 7/14/2010 26 Female 176 lb 7/26/2010 Physician Portugal
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 7/7/2010 26 Female 176 lb 8/2/2010 Physician Portugal
Primary
Secondary
Concomitant
Tremor Other Serious 5/1/2008 52 Male 8/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 8/26/2010 Korea, Republic Of
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Death 8/31/2010 45 Male 10/8/2010 Physician Puerto Rico
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Death 8/31/2010 45 Male 10/29/2010 Physician Puerto Rico
Primary
Secondary
Concomitant
Paraesthesia Required Intervention 11/3/2010 89 Male 11/3/2010 Pharmacist United States
Primary
Concomitant
Urinary Retention Other Serious 2/16/2004 63 Male 11/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Normal Newborn Hospitalization 26 Female 12/29/2010 Other Health Professional Japan
Primary
Concomitant
Hypertension Hospitalization 10/22/2010 47 Male 2/9/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Hyperbilirubinaemia Hospitalization 10/4/2010 47 Male 295 lb 3/24/2011 Other Health Professional Canada
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 4/15/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Hyperbilirubinaemia Hospitalization 10/4/2010 47 Male 295 lb 4/21/2011 Other Health Professional Canada
Primary
Concomitant
Mucosal Inflammation Hospitalization 10/4/2010 47 Male 295 lb 4/22/2011 Physician Canada
Primary
Secondary
Concomitant
Erythema Other Serious 4/4/2011 2 Male 24 lb 4/29/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pallor Other Serious 4/4/2011 2 Male 5/9/2011 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Disability 1/1/2011 2 Male 5/6/2011 Physician United Kingdom
Primary
Concomitant
Encephalitis Hospitalization 38 Male 5/23/2011 Other Health Professional Japan
Primary
Concomitant
Bk Virus Infection Other Serious 10/4/2010 47 Male 295 lb 5/25/2011 Other Health Professional Canada
Primary
Concomitant
Rhabdomyolysis Other Serious 5/13/2011 15 Male 5/31/2011 Physician Australia
Primary
Secondary
Encephalitis Hospitalization 38 Male 6/1/2011 Other Health Professional Japan
Primary
Concomitant
Hyperplasia Other Serious 2/16/2004 63 Male 6/2/2011 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 5/13/2011 15 Male 6/6/2011 Physician Australia
Primary
Secondary
Cystitis Haemorrhagic Other Serious 10/4/2010 47 Male 295 lb 6/8/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Bk Virus Infection Hospitalization 10/4/2010 47 Male 295 lb 6/27/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/4/2010 47 Male 295 lb 6/29/2011 Other Health Professional Canada
Primary
Concomitant
Respiratory Failure Death 10/4/2010 47 Male 295 lb 7/1/2011 Other Health Professional Canada
Primary
Concomitant
Dehydration Hospitalization 10/4/2010 47 Male 295 lb 7/5/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Hypertension Life Threatening 4/22/2010 13 Male 90 lb 7/5/2011 Physician Japan
Primary
Concomitant
Mucosal Inflammation Other Serious 10/4/2010 47 Male 295 lb 7/26/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 5/18/2011 15 Male 8/5/2011 Physician Australia
Primary
Secondary
Rhabdomyolysis Other Serious 5/18/2011 15 Male 8/9/2011 Physician Australia
Primary
Secondary
Bedridden Life Threatening 22 Female 8/10/2011 Other Health Professional China
Primary
Concomitant
Cardiac Murmur Hospitalization 65 Male 8/16/2011 United States
Primary
Concomitant
Cytomegalovirus Test Positive Other Serious 8/31/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 65 Male 9/8/2011 Other Health Professional United States
Primary
Concomitant
Toxicity To Various Agents Hospitalization 65 Male 9/9/2011 Other Health Professional United States
Primary
Concomitant
Blood Pressure Increased Hospitalization 65 Male 9/21/2011 Other Health Professional United States
Primary
Concomitant
Lung Consolidation Other Serious 1/19/2011 3 Male 35 lb 9/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 33 lb 9/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 65 Male 9/23/2011 Other Health Professional United States
Primary
Concomitant
Periorbital Oedema Life Threatening 1/27/2011 6 Female 40 lb 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cytomegalovirus Infection Life Threatening 1/19/2011 3 Male 35 lb 10/3/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Deep Vein Thrombosis Death 12/7/2010 6 Female 40 lb 10/4/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 35 lb 10/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 1/1/2011 4 Male 37 lb 10/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 6 Female 40 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data