Acyclovir combined with Melphalan Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Febrile Neutropenia Other Serious 40 Male 165 lb 6/25/2009 Physician Spain
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 11/4/2007 56 Male 155 lb 7/31/2009 Physician United States
Primary
Secondary
Concomitant
Weight Bearing Difficulty Hospitalization 8/3/2009 79 Male 151 lb 8/11/2009 Physician United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/1999 Female 192 lb 9/2/2009 Physician United States
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 9/9/2008 Male 168 lb 9/9/2009 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 12/1/2005 Male 136 lb 1/15/2010 Physician United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/1999 Female 192 lb 1/15/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 1/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ureteric Obstruction Other Serious 10/4/2009 69 Male 154 lb 1/14/2010 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 7/6/2005 Male 1/21/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 7/30/2001 Female 115 lb 1/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 11/1/2005 Female 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 11/18/2009 Female 234 lb 1/27/2010 Physician United States
Primary
Secondary
Concomitant
Erythema Hospitalization 11/18/2009 69 Female 234 lb 2/3/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 2/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue Disability 1/19/2010 Female 2/4/2010 Physician Finland
Primary
Secondary
Concomitant
Arrhythmia Death 12/10/2009 Male 182 lb 2/5/2010 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 10/11/2004 Female 195 lb 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/1999 Female 192 lb 2/9/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/20/1999 Male 178 lb 2/11/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2000 Male 2/11/2010 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2007 Male 170 lb 2/11/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2000 Female 140 lb 2/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/9/2002 Male 136 lb 2/15/2010 Physician United States
Primary
Concomitant
Transaminases Increased Other Serious 2/16/2010 Physician Spain
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/20/1999 Male 178 lb 3/11/2010 Consumer United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 5/1/2009 3/18/2010 Physician Spain
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 3/18/2010 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2004 Female 195 lb 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2007 Male 170 lb 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Death Unknown 3/16/2010 Brazil
Primary
Secondary
Concomitant
Cardiotoxicity Death Unknown 3/16/2010 Brazil
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Death Unknown 3/16/2010 Brazil
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2000 Male 3/22/2010 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 Female 3/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/30/2001 Female 115 lb 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 12/1/2002 Male 178 lb 3/25/2010 Consumer United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 Female 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/2000 Female 140 lb 3/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 3/30/2010 Physician United States
Primary
Concomitant
Tremor Hospitalization 3/14/2010 67 Male 203 lb 4/1/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/22/2008 64 Male 4/5/2010 Other Health Professional United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 3/18/2010 56 Male 4/7/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/2/2000 Female 4/7/2010 Other Health Professional United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 40 Female 4/2/2010 Physician Japan
Primary
Concomitant
Oedema Peripheral Other Serious 3/6/2010 49 Male 184 lb 4/8/2010 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 6/22/2005 80 Female 181 lb 4/9/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 5/12/2005 60 Male 136 lb 4/9/2010 Other Health Professional United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2004 64 Female 195 lb 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Other Serious 3/17/2010 54 Female 165 lb 4/14/2010 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 4/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2/1/2010 59 Female 150 lb 4/23/2010 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 4/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2005 61 Male 245 lb 4/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Other Serious 3/17/2010 54 Female 165 lb 5/4/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 5/4/2010 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 9 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 5 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 9 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 11 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 11 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 5 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Venoocclusive Disease Death 13 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Venoocclusive Disease Death 1 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Sepsis Death 7 5/4/2010 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 2 5/4/2010 Physician United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 1/1/2007 65 Male 170 lb 5/12/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/2/2000 Female 5/12/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 44 Male 5/12/2010 United States
Primary
Secondary
Concomitant
Tremor Other Serious 2/6/2003 66 Female 5/13/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2002 58 Female 115 lb 5/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/25/2010 43 Male 5/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/22/2010 55 Female 185 lb 5/19/2010 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 7/12/2007 39 Male 5/20/2010 Physician United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/1/2006 25 Male 172 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/25/2010 43 Male 6/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2004 64 Female 195 lb 6/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 10/4/2009 69 Male 150 lb 6/2/2010 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 5/22/2010 63 Female 123 lb 6/11/2010 Physician United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/1/2006 25 Male 172 lb 6/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/11/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2002 58 Female 115 lb 6/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/1/2006 25 Male 172 lb 6/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 5/31/2010 63 Female 131 lb 6/15/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/2/2000 Female 6/18/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2005 61 Male 245 lb 6/21/2010 United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 6/4/2010 63 Female 131 lb 6/22/2010 Physician United States
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/22/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 61 Male 245 lb 6/29/2010 United States
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/30/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/21/2010 63 Female 145 lb 6/30/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Life Threatening 48 Male 6/23/2010 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 7/1/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Death 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Death 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Death 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 7/5/2010 United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 6/22/2005 80 Female 181 lb 7/5/2010 United States
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 7/8/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/2000 52 Female 140 lb 7/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Restrictive Cardiomyopathy Other Serious 6/21/2010 63 Female 7/9/2010 Physician United States
Primary
Secondary
Concomitant
Viral Myocarditis Other Serious 55 Male 7/16/2010 Physician Japan
Primary
Concomitant
Venoocclusive Disease Other Serious 8/26/2010 Korea, Republic Of
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 8/26/2010 Korea, Republic Of
Primary
Secondary
Concomitant
Engraftment Syndrome Death Unknown 8/26/2010 Korea, Republic Of
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 12/27/2009 63 Male 9/16/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2000 Female 9/24/2010 Other Health Professional United States
Primary
Concomitant
Cataract Hospitalization 6/2/2010 9/30/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 1 Female 9/30/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 7 Female 9/30/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/10/2009 4 Female 31 lb 10/8/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/10/2009 4 Female 31 lb 10/11/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2000 Female 10/13/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2002 58 Female 115 lb 10/15/2010 United States
Primary
Secondary
Concomitant
Pruritus Hospitalization 9/30/2009 18 Female 137 lb 10/18/2010 Physician Japan
Primary
Concomitant
Leukaemia Recurrent Other Serious 3 Female 10/12/2010 Physician United States
Primary
Concomitant
Death Death 10/28/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Death Death 10/28/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 10/28/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Death 9/21/2009 62 Female 126 lb 11/3/2010 Physician Japan
Primary
Concomitant
Mucosal Inflammation Other Serious 11/12/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Death Death 11/12/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Death Death 11/12/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 12/1/2002 52 Male 178 lb 11/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 6/24/2009 15 Male 126 lb 11/23/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 2/11/2009 54 Male 152 lb 11/23/2010 Consumer Japan
Primary
Concomitant
Rash Other Serious 6/10/2010 2 Female 24 lb 11/24/2010 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 5/26/2010 Male 18 lb 11/24/2010 Physician Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 3/1/2009 54 Male 152 lb 11/24/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 5/14/2010 2 Female 24 lb 11/29/2010 Physician Japan
Primary
Concomitant
Hepatitis B Other Serious 10/11/2010 64 Female 161 lb 11/30/2010 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 6/8/2010 63 Female 192 lb 12/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Disorientation Death 4/13/2009 52 Male 117 lb 1/10/2011 Physician Japan
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 1 Female 2/7/2011 Physician Japan
Primary
Concomitant
Neutropenia Other Serious 7 Female 2/7/2011 Physician Japan
Primary
Concomitant
Asthenia 76 Female 2/28/2011 Consumer United States
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 7/2/2003 55 Male 187 lb 3/17/2011 United States
Primary
Secondary
Concomitant
Epistaxis Death 1/1/2010 75 Male 7/12/2010 Physician United States
Primary
Concomitant
Multi-organ Failure Death 4/25/2010 43 Male 168 lb 4/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 1/2/2011 5/11/2011 Consumer United States
Primary
Secondary
Concomitant
Atrial Fibrillation Death 12/28/2010 68 Female 5/10/2011 Pharmacist United States
Primary
Concomitant
Venoocclusive Disease Other Serious 5/16/2011 Physician Serbia
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 5/16/2011 Physician Serbia
Primary
Secondary
Concomitant
Chest Pain Hospitalization 4/21/2011 5/16/2011 Physician Italy
Primary
Secondary
Concomitant

Drug Data