Actos combined with Toprol-XL

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sudden Cardiac Death Other Serious 57 Male 225 lb 1/6/2006 United States
Primary
Secondary
Concomitant
Road Traffic Accident Hospitalization 1/1/2000 42 Female 168 lb 1/17/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Other Serious 11/1/2003 68 Female 251 lb 1/19/2006 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 10/1/2005 Female 1/20/2006 Physician United States
Primary
Secondary
Concomitant
Pubic Rami Fracture Other Serious 6/11/2005 60 Female 187 lb 1/10/2006 Physician United States
Primary
Concomitant
Drug Interaction Other Serious 2/1/2005 62 Male 1/24/2006 United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 8/1/2005 57 Male 1/27/2006 Physician United States
Primary
Secondary
Concomitant
Road Traffic Accident Other Serious 1/1/2000 53 Female 190 lb 2/3/2006 Physician United States
Primary
Concomitant
Scratch Other Serious 10/1/2004 80 Male 180 lb 2/1/2006 Physician United States
Primary
Concomitant
Weight Loss Poor Other Serious Female 2/3/2006 United States
Primary
Secondary
Concomitant
Rash Hospitalization 6/25/2005 Male 225 lb 11/4/2005 Pharmacist United States
Primary
Concomitant
Thyroid Disorder Hospitalization 11/1/2002 63 Female 190 lb 2/21/2006 Lawyer United States
Primary
Concomitant
Tremor Other Serious 10/1/2005 51 Male 2/23/2006 Consumer United States
Primary
Secondary
Concomitant
Muscle Spasms 1/1/2005 Female 1/20/2006 United States
Primary
Secondary
Concomitant
Dry Mouth 12/7/2005 83 Male 2/27/2006 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2005 Female 165 lb 3/1/2006 Consumer United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 2/2/2006 68 Female 181 lb 2/23/2006 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 5/1/2004 53 Female 3/3/2006 Physician United States
Primary
Concomitant
Syncope Vasovagal Other Serious 11/30/2002 52 Female 3/9/2006 Physician United States
Primary
Concomitant
Sudden Cardiac Death Death Female 278 lb 3/13/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Death 4/1/2004 61 Female 3/14/2006 Lawyer United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2000 53 Female 190 lb 3/15/2006 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 3/6/2003 80 Male 147 lb 3/13/2006 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2000 53 Female 190 lb 3/21/2006 Physician United States
Primary
Concomitant
Respiration Abnormal 1/1/2005 61 Male 1/20/2006 Consumer United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/1/2002 61 Female 198 lb 3/20/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/31/2003 68 Female 251 lb 3/24/2006 Lawyer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 3/10/2006 80 Male 3/27/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 5/28/2001 81 Female 146 lb 3/29/2006 Lawyer United States
Primary
Concomitant
Hypoglycaemia 10/13/2005 64 Male 267 lb 1/20/2006 Physician United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 5/1/2002 54 Male 3/27/2006 Lawyer United States
Primary
Concomitant
Vomiting 10/27/2005 73 Male 170 lb 1/20/2006 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 5/28/2001 81 Female 146 lb 4/4/2006 Physician United States
Primary
Concomitant
Weight Decreased 10/1/2005 69 Male 203 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 11/1/2005 72 Female 220 lb 1/20/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 10/24/2003 59 Male 4/10/2006 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious Female 3/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Myositis Hospitalization 2/21/2006 64 Male 165 lb 3/31/2006 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective 11/1/2005 71 Male 201 lb 1/20/2006 Other Health Professional United States
Primary
Concomitant
Road Traffic Accident Hospitalization 10/27/2000 42 Female 168 lb 4/12/2006 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious Female 4/6/2006 United States
Primary
Secondary
Concomitant
Stress Hospitalization 5/1/2004 53 Female 231 lb 4/17/2006 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 3/30/2006 51 Female 4/17/2006 Consumer United States
Primary
Concomitant
Tremor Female 4/20/2006 Consumer United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 10/24/2003 59 Male 4/28/2006 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2000 64 Male 4/19/2006 Consumer United States
Primary
Secondary
Concomitant
Medical Device Complication Other Serious 2/1/2006 Male 175 lb 5/9/2006 Consumer United States
Primary
Secondary
Concomitant
Ligament Disorder Hospitalization 2/1/2002 54 Female 209 lb 5/11/2006 Physician United States
Primary
Concomitant
Heart Rate Decreased Hospitalization 5/8/2006 65 Female 232 lb 5/12/2006 Other Health Professional United States
Primary
Concomitant
Medical Device Complication Other Serious 2/1/2006 Male 175 lb 5/19/2006 Consumer United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 1/1/2005 61 Male 178 lb 5/16/2006 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 78 Female 5/17/2006 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/6/2003 75 Male 147 lb 5/17/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2006 53 Female 126 lb 6/8/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 2/1/2006 70 Female 225 lb 4/24/2006 Consumer United States
Primary
Concomitant
Myalgia Other Serious 70 Male 4/20/2006 Physician United States
Primary
Concomitant
Muscle Spasms 1/1/2005 Female 4/20/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/1/2006 Male 175 lb 6/16/2006 Physician United States
Primary
Secondary
Concomitant
Stomach Discomfort 2/1/2006 68 Female 160 lb 5/16/2006 United States
Primary
Concomitant
Disease Progression Hospitalization 4/17/2006 60 Female 6/28/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased 7/14/2005 49 Male 248 lb 4/17/2006 Consumer United States
Primary
Concomitant
Multiple Sclerosis Hospitalization 3/6/2006 57 Female 6/29/2006 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 1/1/2006 74 Female 205 lb 6/28/2006 United States
Primary
Concomitant
Renal Failure Hospitalization 1/1/2006 74 Female 205 lb 6/28/2006 United States
Primary
Concomitant
Blister 3/15/2006 53 Male 350 lb 4/17/2006 Consumer United States
Primary
Concomitant
Dizziness 2/14/2006 66 Male 218 lb 4/17/2006 United States
Primary
Concomitant
Swelling Other Serious 1/1/2005 61 Male 178 lb 6/30/2006 Physician United States
Primary
Concomitant
Albumin Urine Present 2/1/2006 59 Male 225 lb 4/17/2006 Consumer United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 3/30/2006 51 Female 7/19/2006 Consumer United States
Primary
Concomitant
Fatigue Male 8/1/2006 Consumer United States
Primary
Concomitant
Vertigo 1/1/2004 Female 279 lb 8/8/2006 Physician United States
Primary
Concomitant
Haematocrit Decreased 4/4/2005 Female 278 lb 8/8/2006 Physician United States
Primary
Concomitant
Platelet Count Increased 1/1/2005 63 Female 256 lb 8/9/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 2/1/2006 70 Female 225 lb 7/12/2006 United States
Primary
Concomitant
Therapeutic Response Unexpected 2/21/2006 47 Female 208 lb 7/19/2006 Consumer United States
Primary
Concomitant
Drug Ineffective Hospitalization 5/1/2006 73 Male 198 lb 8/28/2006 Consumer United States
Primary
Concomitant
Swelling Face Other Serious 8/17/2006 59 Male 175 lb 9/1/2006 Other Health Professional United States
Primary
Concomitant
Tremor 6/19/2006 33 Female 220 lb 7/19/2006 Consumer United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 7/1/2006 44 Female 220 lb 9/5/2006 Consumer United States
Primary
Concomitant
Urticaria Other Serious 8/17/2006 59 Male 175 lb 9/1/2006 Other Health Professional United States
Primary
Concomitant
Cyst Required Intervention 7/1/2005 50 Male 212 lb 9/20/2006 United States
Primary
Concomitant
Chromaturia 4/1/2006 67 Male 230 lb 7/19/2006 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected 5/13/2006 63 Male 226 lb 7/19/2006 Consumer United States
Primary
Concomitant
Hypertension Required Intervention 48 Male 10/3/2006 Consumer United States
Primary
Concomitant
Blood Creatinine Increased Other Serious 4/17/2006 79 Male 8/9/2006 Physician United States
Primary
Concomitant
Hypertension Other Serious Male 10/9/2006 Pharmacist United States
Primary
Secondary
Visual Acuity Reduced Other Serious 59 Male 10/25/2006 Consumer United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 2/2/2001 Male 261 lb 10/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 4/28/2006 70 Male 225 lb 10/30/2006 Physician Canada
Primary
Secondary
Concomitant
Dysphonia 4/1/2006 79 Male 10/30/2006 Consumer United States
Primary
Concomitant
Hypersensitivity Other Serious 8/17/2006 59 Male 170 lb 10/25/2006 Physician United States
Primary
Concomitant
Weight Decreased 8/1/2005 55 Male 285 lb 10/27/2006 Other Health Professional United States
Primary
Concomitant
Nervous System Disorder Other Serious 9/1/2006 63 Male 175 lb 11/3/2006 Physician United States
Primary
Concomitant
Drug Ineffective Hospitalization 1/1/2004 82 Male 165 lb 11/21/2006 Consumer United States
Primary
Concomitant
Fatigue Male 11/28/2006 Consumer United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 4/28/2006 70 Male 225 lb 12/5/2006 Physician Canada
Primary
Secondary
Concomitant
Acute Lymphocytic Leukaemia Other Serious 10/1/2005 44 Female 300 lb 11/28/2006 Other Health Professional United States
Primary
Concomitant
Myelodysplastic Syndrome Death 9/20/2006 73 Female 11/28/2006 Physician United States
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/1/2006 Male 160 lb 12/13/2006 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 59 Male 12/14/2006 Consumer United States
Primary
Secondary
Concomitant
Vitreous Floaters Required Intervention 12/5/2000 54 Male 236 lb 12/5/2006 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/13/2006 54 Female 220 lb 12/11/2006 Consumer United States
Primary
Concomitant
Anosmia 7/1/2005 83 Male 12/28/2006 Consumer United States
Primary
Secondary
Concomitant
Dry Mouth 12/7/2005 83 Male 12/28/2006 Consumer United States
Primary
Concomitant
Urine Flow Decreased Male 12/28/2006 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 8/9/2006 Female 134 lb 8/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/1/2006 Male 225 lb 1/3/2007 Other Health Professional United States
Primary
Concomitant
Treatment Noncompliance Required Intervention 7/1/2005 67 Female 180 lb 12/28/2006 United States
Primary
Concomitant
Purpura 1/1/2005 Male 10/12/2006 United States
Primary
Concomitant
Incorrect Dose Administered 61 Male 269 lb 1/9/2007 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma 6/17/2006 75 Female 180 lb 10/16/2006 Physician United States
Primary
Concomitant
Diarrhoea 7/23/2006 73 Male 276 lb 10/16/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 1/1/2005 69 Male 192 lb 10/16/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/1/2006 Male 175 lb 2/7/2007 Physician United States
Primary
Secondary
Concomitant
Low Density Lipoprotein Increased Other Serious 45 Male 8/19/2005 Physician United States
Primary
Secondary
Concomitant
Blood Uric Acid Increased Other Serious 5/25/2005 63 Male 274 lb 8/19/2005 United States
Primary
Concomitant
Overdose 71 Male 3/7/2007 Consumer United States
Primary
Concomitant
Fatigue 40 Male 3/7/2007 Consumer United States
Primary
Concomitant
Lung Neoplasm Malignant Death 76 Male 3/9/2007 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 1/28/2007 79 Male 3/29/2007 Physician United States
Primary
Secondary
Concomitant
Myasthenia Gravis Other Serious 10/17/2006 71 Male 182 lb 4/11/2007 United States
Primary
Secondary
Concomitant
Hypersomnia 10/19/2006 53 Female 205 lb 1/12/2007 Consumer United States
Primary
Concomitant
Stress 10/1/2006 65 Male 194 lb 1/12/2007 Consumer United States
Primary
Concomitant
Tremor 10/26/2006 62 Male 200 lb 1/12/2007 Consumer United States
Primary
Concomitant
Renal Function Test Abnormal 1/1/2006 68 Female 220 lb 1/12/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 12/5/2006 68 Female 170 lb 1/12/2007 Consumer United States
Primary
Concomitant
Weight Decreased 8/1/2006 59 Female 200 lb 1/12/2007 Consumer United States
Primary
Secondary
Concomitant
Medication Error Life Threatening 3/9/2007 69 Female 188 lb 3/13/2007 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 11/17/2006 71 Male 154 lb 5/3/2007 Physician United States
Primary
Concomitant
Blood Pressure Increased 11/22/2006 83 Male 1/23/2007 United States
Primary
Concomitant
Rash 12/11/2006 49 Female 217 lb 2/16/2007 Physician United States
Primary
Concomitant
Somnolence 12/31/2006 Male 2/16/2007 United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 2/15/2007 56 Female 5/9/2007 Consumer United States
Primary
Concomitant
Hyperglycaemia Other Serious 12/27/2004 67 Female 5/22/2007 Lawyer United States
Primary
Concomitant
Pyrexia Hospitalization 1/28/2007 79 Male 5/17/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/28/2007 79 Male 5/17/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/1/2006 66 Male 220 lb 5/31/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 61 Female 6/11/2007 Consumer United States
Primary
Concomitant
Syncope 1/1/2007 65 Male 5/17/2007 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 5/30/2007 71 Male 260 lb 6/6/2007 Consumer United States
Primary
Concomitant
Sensation Of Foreign Body Other Serious 1/1/2006 68 Female 6/12/2007 Consumer United States
Primary
Concomitant
Constipation 11/1/2006 79 Male 5/17/2007 United States
Primary
Concomitant
Blood Urea Increased 1/31/2007 50 Female 4/10/2007 Physician United States
Primary
Concomitant
Aplastic Anaemia Death 6/22/2005 73 Male 155 lb 6/13/2007 Physician United States
Primary
Concomitant
Oedema Peripheral Required Intervention 1/1/2003 64 Female 330 lb 6/14/2007 Consumer United States
Primary
Concomitant
Fatigue 12/1/2006 69 Female 230 lb 4/10/2007 Consumer United States
Primary
Concomitant
Dyspnoea 87 Female 210 lb 6/22/2007 Consumer United States
Primary
Concomitant
Vision Blurred 71 Male 200 lb 6/25/2007 United States
Primary
Concomitant
Respiratory Disorder 3/24/2006 79 Female 123 lb 6/25/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased 8/1/2006 59 Female 200 lb 6/25/2007 Consumer United States
Primary
Secondary
Concomitant

Drug Data