Actos combined with Pravastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Fall Death 3/4/2006 78 Female 3/9/2006 Japan
Primary
Concomitant
Sudden Cardiac Death Death 3/3/2006 78 Female 3/23/2006 Japan
Primary
Concomitant
Sudden Death Death 3/3/2006 78 Female 4/13/2006 Japan
Primary
Concomitant
Occult Blood Positive Other Serious 4/5/2006 78 Male 4/17/2006 Japan
Primary
Secondary
Concomitant
Metastases To Lymph Nodes Other Serious 4/5/2006 78 Male 4/24/2006 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 3/14/2006 57 Male 5/3/2006 Japan
Primary
Concomitant
Oedema Hospitalization 11/15/2005 78 Male 5/19/2006 Physician France
Primary
Concomitant
Weight Increased Hospitalization 5/12/2006 75 Male 6/6/2006 Physician Japan
Primary
Concomitant
Tongue Oedema Life Threatening 2/12/2006 79 Female 6/19/2006 France
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/10/2006 75 Male 7/5/2006 Physician Japan
Primary
Concomitant
Paraesthesia Hospitalization 7/14/2006 78 Male 210 lb 7/31/2006 Consumer United States
Primary
Secondary
Concomitant
Sensory Loss Hospitalization 7/14/2006 78 Male 210 lb 8/10/2006 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Required Intervention 6/30/2006 77 Female 8/25/2006 United Kingdom
Primary
Concomitant
Urticaria Generalised Other Serious 12/26/2006 63 Female 1/9/2007 Japan
Primary
Concomitant
Urticaria Other Serious 12/26/2006 64 Female 1/30/2007 Japan
Primary
Concomitant
Vision Blurred Other Serious 6/30/2006 77 Female 3/1/2007 United Kingdom
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 3/1/2007 65 Female 4/9/2007 Japan
Primary
Concomitant
Refractory Anaemia With An Excess Of Blasts Hospitalization 3/6/2007 65 Female 4/24/2007 Japan
Primary
Concomitant
Transient Ischaemic Attack Other Serious 6/1/2006 59 Female 5/10/2007 United States
Primary
Concomitant
Visual Disturbance Other Serious 3/27/2007 71 Female 5/7/2007 United Kingdom
Primary
Concomitant
Dyspnoea Exertional Hospitalization 3/12/2007 79 Female 6/29/2007 Japan
Primary
Concomitant
Pyrexia Hospitalization 11/13/2006 Female 137 lb 8/10/2007 Physician Japan
Primary
Concomitant
Acute Pulmonary Oedema Life Threatening 1/1/2007 73 Male 8/9/2007 France
Primary
Concomitant
Torsade De Pointes Hospitalization 7/20/2007 74 Female 250 lb 8/13/2007 Physician United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 8/15/2007 Male 318 lb 8/29/2007 United States
Primary
Concomitant
Pyrexia Life Threatening 6/19/2007 66 Female 9/20/2007 Other Health Professional Japan
Primary
Concomitant
Urticaria Other Serious 12/26/2006 64 Female 9/28/2007 Japan
Primary
Concomitant
Mitral Valve Incompetence Life Threatening 6/19/2007 66 Female 10/11/2007 Japan
Primary
Concomitant
Alveolitis Fibrosing Other Serious 1/1/2006 79 Male 10/18/2007 United Kingdom
Primary
Concomitant
Dysphonia 81 Female 10/26/2007 Consumer United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 8/1/2007 Male 318 lb 10/29/2007 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 10/1/2007 75 Male 10/31/2007 Physician Japan
Primary
Concomitant
Mitral Valve Incompetence Life Threatening 6/19/2007 66 Female 10/29/2007 Japan
Primary
Concomitant
Orthostatic Hypotension Hospitalization 8/1/2007 Male 318 lb 11/2/2007 United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 8/1/2007 Male 318 lb 11/13/2007 United States
Primary
Concomitant
Weight Increased Life Threatening 6/19/2007 66 Female 11/13/2007 Japan
Primary
Concomitant
Orthostatic Hypotension Hospitalization 8/1/2007 Male 318 lb 12/3/2007 United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 8/18/2007 66 Female 12/4/2007 Japan
Primary
Concomitant
Orthostatic Hypotension Hospitalization 8/1/2007 Male 318 lb 12/11/2007 United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 8/1/2007 Male 318 lb 12/18/2007 United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 8/1/2007 Male 318 lb 1/3/2008 United States
Primary
Concomitant
Cardiac Failure Acute Hospitalization 12/17/2007 82 Female 1/8/2008 Japan
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Female 184 lb 2/14/2008 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Life Threatening 5/1/2006 81 Female 2/20/2008 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 Male 148 lb 2/25/2008 Physician United States
Primary
Concomitant
Pulmonary Congestion Hospitalization 2/2/2008 82 Female 3/26/2008 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 263 lb 4/16/2008 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 4/25/2008 79 Male 201 lb 5/2/2008 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 4/25/2008 79 Male 201 lb 5/7/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 263 lb 5/7/2008 Physician United States
Primary
Concomitant
Vertigo Hospitalization 4/2/2008 61 Female 5/19/2008 Consumer United States
Primary
Concomitant
Syncope Life Threatening 5/2/2008 Male 6/25/2008 Physician United States
Primary
Concomitant
Retinal Artery Embolism 1/1/2006 59 Male 242 lb 4/10/2008 Consumer United States
Primary
Concomitant
Cerebral Infarction Hospitalization 2/1/2008 82 Female 7/7/2008 Japan
Primary
Concomitant
Myocardial Infarction Hospitalization 1/21/2005 56 Male 211 lb 7/25/2008 Consumer United States
Primary
Concomitant
Retinal Ischaemia 1/1/2006 59 Male 242 lb 7/7/2008 Consumer United States
Primary
Concomitant
Polypectomy Other Serious 12/1/2007 Female 235 lb 8/15/2008 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 3/6/2008 68 Male 212 lb 7/7/2008 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 6/6/2008 84 Female 76 lb 8/22/2008 Pharmacist Japan
Primary
Concomitant
Myocardial Infarction Hospitalization 1/21/2005 56 Male 211 lb 8/29/2008 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 6/6/2008 84 Female 76 lb 9/5/2008 Pharmacist Japan
Primary
Concomitant
Visual Impairment Other Serious 9/10/2008 77 Female 9/16/2008 United Kingdom
Primary
Concomitant
Hypoacusis Other Serious 1/1/2007 Female 168 lb 10/1/2008 Consumer United States
Primary
Concomitant
Weight Increased Required Intervention 1/1/2007 70 Female 191 lb 11/6/2008 Consumer United States
Primary
Concomitant
Prostate Cancer Recurrent Other Serious 11/3/2008 Male 200 lb 12/2/2008 United States
Primary
Concomitant
Restlessness Hospitalization 11/5/2008 74 Male 215 lb 12/8/2008 Consumer United States
Primary
Concomitant
Hepatitis Fulminant Hospitalization 10/1/2008 70 Male 12/9/2008 Japan
Primary
Secondary
Microcytic Anaemia Other Serious 4/1/2008 73 Female 12/23/2008 United Kingdom
Primary
Concomitant
Photophobia Hospitalization 10/1/2007 56 Female 1/5/2009 Germany
Primary
Concomitant
Hypochromic Anaemia Other Serious 4/1/2008 73 Female 1/12/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 10/1/2007 56 Female 1/14/2009 Other Health Professional Germany
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 175 lb 1/21/2009 Consumer United States
Primary
Concomitant
Drug Hypersensitivity Life Threatening 1/26/2009 Female 170 lb 1/26/2009 United States
Primary
Concomitant
Deafness 3/1/2009 66 Male 3/16/2009 Consumer United States
Primary
Concomitant
Pulmonary Congestion Hospitalization 1/1/2009 79 Female 4/2/2009 Japan
Primary
Concomitant
Retroperitoneal Haemorrhage Hospitalization 12/1/2008 71 Female 5/20/2009 Physician United States
Primary
Concomitant
Prothrombin Level Decreased Life Threatening 10/10/2008 65 Male 5/19/2009 Japan
Primary
Secondary
Type 2 Diabetes Mellitus Other Serious 3/21/2003 36 Female 188 lb 6/5/2009 United States
Primary
Concomitant
Wrist Fracture Required Intervention 1/1/2003 61 Female 220 lb 6/17/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 162 lb 6/23/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 Male 148 lb 6/30/2009 Physician United States
Primary
Concomitant
Scar Hospitalization 3/10/2009 78 Female 6/29/2009 Physician Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 3/29/2009 77 Female 7/14/2009 Japan
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 Male 148 lb 7/20/2009 Physician United States
Primary
Concomitant
Renal Impairment Other Serious 1/1/2004 Male 280 lb 8/18/2009 Consumer United States
Primary
Secondary
Concomitant
Pruritus Generalised 12/10/2008 Female 140 lb 8/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Flushing 12/1/2008 Female 8/22/2009 United States
Primary
Concomitant
Skin Burning Sensation Male 8/22/2009 United States
Primary
Concomitant
Muscle Spasms 7/1/2009 Female 8/23/2009 United States
Primary
Secondary
Concomitant
Feeling Hot Male 8/23/2009 United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 Male 148 lb 8/28/2009 Physician United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 1/1/2005 46 Male 245 lb 9/23/2009 United States
Primary
Secondary
Concomitant
Breast Pain 82 Female 212 lb 10/2/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 Male 148 lb 10/2/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 8/26/2009 48 Female 165 lb 9/30/2009 Pharmacist United States
Primary
Concomitant
Vision Blurred 8/1/2009 69 Male 11/5/2009 Consumer
Primary
Concomitant
Intracranial Tumour Haemorrhage Death 5/5/2009 76 Female 176 lb 11/25/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 11/5/2009 70 Female 202 lb 11/20/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 263 lb 12/1/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 162 lb 12/1/2009 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 6/1/2009 Female 250 lb 12/9/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 6/1/2009 Female 250 lb 12/10/2009 Other Health Professional United States
Primary
Concomitant
Tremor Required Intervention 5/1/2009 65 Female 240 lb 11/17/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 Male 148 lb 1/21/2010 Physician United States
Primary
Concomitant
Left Ventricular Dysfunction Other Serious 1/13/2010 Male 170 lb 2/1/2010 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 6/1/2009 Female 266 lb 2/19/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 6/1/2009 Female 266 lb 2/25/2010 Other Health Professional United States
Primary
Concomitant
Psoriasis Other Serious 4/1/2009 Female 196 lb 3/12/2010 Consumer United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 8/1/2007 Male 318 lb 3/25/2010 Other Health Professional United States
Primary
Concomitant
Prostate Cancer Other Serious 1/18/2010 59 Male 176 lb 4/21/2010 Physician Germany
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 1/18/2010 59 Male 176 lb 4/28/2010 Physician Germany
Primary
Secondary
Concomitant
Pollakiuria Other Serious Male 245 lb 4/30/2010 Consumer United States
Primary
Concomitant
Blood Glucose Increased 72 Male 217 lb 5/3/2010 Other Health Professional United States
Primary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 5/13/2010 United States
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 1/18/2010 59 Male 176 lb 5/27/2010 Physician Germany
Primary
Secondary
Concomitant
Haemorrhoid Operation Hospitalization 3/24/2010 60 Female 5/26/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Papular Hospitalization 2/15/2010 52 Male 6/4/2010 France
Primary
Concomitant
Palpitations Other Serious 12/1/2009 56 Male 6/15/2010 Physician
Primary
Concomitant
Renal Failure Acute Hospitalization 5/18/2010 68 Female 6/14/2010 Japan
Primary
Secondary
Unresponsive To Stimuli Hospitalization 3/27/2010 76 Male 6/28/2010 Switzerland
Primary
Secondary
Concomitant
Weight Increased 1/1/2008 48 Female 341 lb 7/7/2010 Consumer United States
Primary
Concomitant
Headache 1/1/2007 73 Female 140 lb 7/16/2010 Consumer United States
Primary
Concomitant
Pain In Extremity 1/1/2008 66 Female 196 lb 7/19/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 12/1/2009 75 Female 146 lb 7/27/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2002 59 Male 212 lb 7/31/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 12/1/2009 75 Female 146 lb 8/13/2010 Other Health Professional United States
Primary
Concomitant
Palpitations Other Serious 12/1/2006 74 Female 170 lb 8/20/2010 Pharmacist Japan
Primary
Concomitant
Palpitations Other Serious 12/1/2006 74 Female 170 lb 8/31/2010 Pharmacist Japan
Primary
Concomitant
Psoriasis Other Serious 4/1/2009 66 Female 196 lb 9/1/2010 Physician United States
Primary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 9/3/2010 United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 48 Female 9/16/2010 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 44 Male 220 lb 9/17/2010 United States
Primary
Secondary
Concomitant
Obesity 62 Female 354 lb 9/20/2010 United States
Primary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 9/30/2010 United States
Primary
Secondary
Concomitant
Bladder Cancer Required Intervention 4/12/2009 72 Male 250 lb 9/29/2010 Other Health Professional United States
Primary
Concomitant
Renal Impairment Other Serious 9/1/2009 47 Female 210 lb 10/5/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 9/2/2010 48 Male 250 lb 9/30/2010 Physician United States
Primary
Concomitant
Renal Impairment Other Serious 9/1/2009 47 Female 210 lb 10/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 10/14/2010 United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 9/1/2009 47 Female 210 lb 10/15/2010 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 8/19/2009 54 Male 230 lb 10/18/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/7/2005 58 Male 174 lb 10/27/2010 United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 70 Male 10/21/2010 United States
Primary
Concomitant
Urinary Retention Other Serious 3/2/2010 67 Male 150 lb 11/5/2010 Physician Japan
Primary
Concomitant
Vomiting 76 Male 11/16/2010 Consumer United States
Primary
Secondary
Concomitant
Nervousness 67 Male 11/16/2010 Consumer United States
Primary
Concomitant
Renal Impairment Other Serious 9/1/2009 47 Female 210 lb 11/22/2010 Consumer United States
Primary
Secondary
Concomitant
Hallucinations, Mixed Other Serious Female 11/24/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/7/2005 58 Male 174 lb 12/24/2010 United States
Primary
Secondary
Concomitant
Death Death 7/30/2010 56 Female 155 lb 12/30/2010 Consumer United States
Primary
Concomitant

Drug Data