Actos combined with Metoprolol

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
High Density Lipoprotein Decreased Other Serious 7/25/2005 57 Male 185 lb 1/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 12/12/2005 Female 126 lb 1/31/2006 Physician United States
Primary
Concomitant
Skin Discolouration Other Serious 12/12/2005 66 Female 146 lb 2/9/2006 Physician United States
Primary
Concomitant
Polyuria Other Serious 1/1/2005 66 Female 3/8/2006 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 5/28/2001 81 Female 146 lb 3/29/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2002 63 Male 176 lb 3/29/2006 Lawyer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 5/28/2001 81 Female 146 lb 4/4/2006 Physician United States
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 12/13/1999 59 Male 176 lb 4/7/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 3/1/2003 53 Female 231 lb 5/3/2006 Lawyer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 3/21/2006 60 Female 172 lb 5/22/2006 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 3/30/2006 65 Female 5/12/2006 United States
Primary
Concomitant
Injection Site Haemorrhage 3/1/2006 63 Male 256 lb 4/17/2006 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 8/1/2005 73 Male 7/25/2006 Canada
Primary
Concomitant
Temperature Intolerance 68 Male 161 lb 8/1/2006 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2006 54 Female 240 lb 8/14/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/22/2006 68 Male 9/11/2006 Physician Germany
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 151 lb 9/26/2006 Physician United States
Primary
Concomitant
Drug Effect Decreased 1/1/2006 62 Female 269 lb 10/2/2006 Consumer United States
Primary
Concomitant
Bladder Spasm Hospitalization 8/1/2006 79 Male 10/2/2006 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 10/11/2006 64 Female 298 lb 10/24/2006 Physician United States
Primary
Concomitant
Interacting
Rash Pruritic Other Serious 2/1/2007 58 Female 183 lb 3/1/2007 Other Health Professional United States
Primary
Concomitant
Fluid Retention Other Serious 10/1/2007 Female 255 lb 10/23/2007 United States
Primary
Concomitant
Coronary Artery Disease Required Intervention 10/24/2007 81 Female 174 lb 10/25/2007 Physician United States
Primary
Concomitant
Rash Pruritic 5/24/2007 52 Female 300 lb 11/16/2007 Physician United States
Primary
Concomitant
Constipation 9/16/2007 64 Male 2/15/2008 United States
Primary
Concomitant
Weight Decreased Life Threatening 5/20/2008 Male 177 lb 5/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 1/14/2008 84 Male 6/20/2008 Consumer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 1/1/2007 Male 226 lb 6/13/2008 Consumer United States
Primary
Concomitant
Visual Impairment Hospitalization 72 Male 7/2/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 6/24/2008 Male 194 lb 6/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Decreased 7/27/2007 65 Male 201 lb 7/29/2008 Other Health Professional United States
Primary
Concomitant
Pruritus 75 Female 239 lb 8/15/2008 Physician United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 10/29/2007 84 Female 9/17/2008 Physician United States
Primary
Concomitant
Renal Cyst Hospitalization 8/27/2007 84 Female 121 lb 10/14/2008 Physician United States
Primary
Concomitant
Renal Cyst Hospitalization 8/27/2007 84 Female 121 lb 10/27/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 2/8/2002 66 Male 196 lb 11/24/2008 Lawyer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 7/1/2008 Female 131 lb 11/21/2008 Physician United States
Primary
Concomitant
Tenderness Hospitalization 12/10/2008 Female 140 lb 12/12/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 1/21/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 1/27/2009 Consumer United States
Primary
Secondary
Concomitant
Ovarian Cancer Other Serious 1/1/2009 69 Female 2/5/2009 Hungary
Primary
Concomitant
Myalgia 11/5/2008 Male 344 lb 2/24/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 3/13/2009 Consumer United States
Primary
Secondary
Concomitant
Laryngeal Cancer Hospitalization 2/1/2008 Male 309 lb 4/3/2009 Physician Germany
Primary
Concomitant
Myelitis Hospitalization 1/1/2009 61 Female 5/7/2009 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 7/15/2005 60 Female 240 lb 5/14/2009 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2006 52 Male 160 lb 5/18/2009 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 5/9/2000 52 Female 190 lb 5/21/2009 United States
Primary
Concomitant
Blood Glucose Abnormal Female 5/27/2009 United States
Primary
Concomitant
Hot Flush 1/1/2007 Male 350 lb 5/27/2009 Consumer United States
Primary
Concomitant
Middle Insomnia 4/1/2009 Male 150 lb 5/27/2009 United States
Primary
Concomitant
Tubulointerstitial Nephritis Life Threatening 1/1/2009 65 Male 5/29/2009 Physician United States
Primary
Concomitant
Tubulointerstitial Nephritis Life Threatening 5/1/2009 65 Male 6/19/2009 Physician United States
Primary
Concomitant
Tubulointerstitial Nephritis Life Threatening 5/1/2009 65 Male 6/26/2009 Physician United States
Primary
Concomitant
Post-thoracotomy Pain Syndrome Other Serious 1/1/2008 Male 7/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Cyst Hospitalization 8/27/2007 84 Female 121 lb 7/2/2009 Physician United States
Primary
Concomitant
Off Label Use Other Serious 2/5/2004 7/7/2009 Physician United States
Primary
Secondary
Concomitant
Tardive Dyskinesia Hospitalization 10/1/2008 61 Female 247 lb 8/12/2009 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 8/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Streptococcal Infection Other Serious 1/1/2008 54 Male 210 lb 8/14/2009 Physician United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 10/3/2006 65 Male 213 lb 8/20/2009 Other Health Professional United States
Primary
Concomitant
Flushing Male 8/22/2009 United States
Primary
Concomitant
Flushing Male 8/22/2009 United States
Primary
Concomitant
Flushing 2/23/2009 Male 8/22/2009 United States
Primary
Concomitant
Muscle Spasms Female 8/22/2009 United States
Primary
Concomitant
Hyperhidrosis 12/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Rash 12/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Pruritus Generalised 4/16/2009 Male 248 lb 8/22/2009 United States
Primary
Concomitant
Myalgia 6/1/2009 Male 225 lb 8/23/2009 United States
Primary
Concomitant
Night Sweats 1/1/2008 Male 188 lb 8/23/2009 United States
Primary
Concomitant
Influenza Like Illness 3/24/2009 66 Male 246 lb 8/14/2009 Physician United States
Primary
Secondary
Concomitant
Hot Flush 1/1/2007 Male 375 lb 8/29/2009 Consumer United States
Primary
Concomitant
Transplant Failure Other Serious 2/5/2004 9/1/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/21/2007 78 Female 9/11/2009 Lawyer United States
Primary
Concomitant
Optic Ischaemic Neuropathy Other Serious 1/31/2005 Male 9/18/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 61 Female 9/15/2009 United States
Primary
Concomitant
Wound Dehiscence Hospitalization 4/2/2009 68 Female 179 lb 9/18/2009 Physician Germany
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 9/17/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 12/1/2008 52 Female 9/21/2009 Lawyer United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 10/3/2006 65 Male 213 lb 10/2/2009 Other Health Professional United States
Primary
Concomitant
In-stent Coronary Artery Restenosis Hospitalization 7/1/2009 Male 260 lb 10/2/2009 Physician United States
Primary
Concomitant
Renal Disorder Other Serious Female 140 lb 10/2/2009 Physician United States
Primary
Concomitant
Unemployment Hospitalization 1/20/2006 73 Male 163 lb 9/22/2009 United States
Primary
Concomitant
Blood Urea Increased 73 Male 10/6/2009 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 10/3/2006 65 Male 213 lb 10/7/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 4/29/2006 Female 138 lb 10/8/2009 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 48 Female 280 lb 10/15/2009 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 11/5/2005 74 Female 147 lb 10/15/2009 Pharmacist United States
Primary
Concomitant
Wheezing Hospitalization 12/1/2008 55 Female 10/17/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/21/2007 79 Female 10/22/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/21/2007 79 Female 10/26/2009 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1998 40 Female 189 lb 11/4/2009 United States
Primary
Concomitant
Skin Ulcer Other Serious 1/1/2006 Male 380 lb 11/4/2009 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 77 Female 10/26/2009 United States
Primary
Concomitant
Pancreatitis Other Serious 57 Male 11/5/2009 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 10/30/2009 Female 280 lb 11/6/2009 Physician United States
Primary
Concomitant
Tobacco User Other Serious 1/1/2009 Male 270 lb 11/10/2009 Consumer
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/21/2007 79 Female 11/4/2009 Consumer United States
Primary
Concomitant
Unevaluable Event Other Serious 77 Female 11/4/2009 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1998 40 Female 189 lb 11/17/2009 United States
Primary
Concomitant
Urticaria 6/6/2008 Male 11/24/2009 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 7/21/2007 79 Female 11/18/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1998 40 Female 189 lb 11/27/2009 United States
Primary
Concomitant
Asthma Other Serious 11/12/2009 Female 270 lb 12/1/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1998 40 Female 189 lb 12/2/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 12/1/2008 47 Female 11/24/2009 Consumer United States
Primary
Concomitant
Tremor 9/28/2009 Female 170 lb 12/3/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 10/1/2006 Male 249 lb 12/1/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 48 Female 280 lb 12/4/2009 United States
Primary
Concomitant
Pancreatitis Hospitalization 10/8/2009 74 Female 194 lb 12/10/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2009 60 Male 224 lb 11/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pressure Of Speech 62 Male 249 lb 12/9/2009 Consumer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1998 40 Female 189 lb 12/15/2009 United States
Primary
Concomitant
Oral Pain 12/5/2009 Female 12/15/2009 Consumer
Primary
Concomitant
Somnolence Other Serious 1/1/2006 Male 380 lb 12/17/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious Female 175 lb 1/11/2010 Consumer United States
Primary
Concomitant
Overdose Hospitalization 11/4/2009 60 Male 260 lb 1/6/2010 Other Health Professional United States
Primary
Concomitant
Xerosis Other Serious 3/25/2003 72 Female 117 lb 1/18/2010 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 2/8/2002 66 Male 196 lb 1/18/2010 Lawyer United States
Primary
Concomitant
Xerosis Other Serious 3/25/2003 72 Female 117 lb 1/19/2010 Physician United States
Primary
Secondary
Concomitant
Dizziness Other Serious 7/1/2009 82 Male 1/22/2010 Consumer United States
Primary
Concomitant
Social Avoidant Behaviour Other Serious 77 Female 1/13/2010 United States
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/2006 60 Female 3/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Limb Fracture Other Serious 1/1/2006 60 Female 223 lb 3/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 10/2/2009 67 Male 185 lb 4/5/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1998 40 Female 189 lb 4/27/2010 United States
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/2005 59 Female 223 lb 5/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2010 68 Male 280 lb 5/5/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 59 Female 4/27/2010 United States
Primary
Concomitant
Vomiting Other Serious 8/1/2007 57 Female 5/10/2010 Lawyer United States
Primary
Concomitant
Vertigo Hospitalization 69 Male 5/11/2010 Lawyer United States
Primary
Concomitant
Muscular Weakness Other Serious Male 170 lb 5/25/2010 Consumer United States
Primary
Concomitant
White Clot Syndrome Other Serious 5/1/2008 57 Female 6/17/2010 Lawyer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/10/2007 68 Male 186 lb 6/28/2010 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Male 220 lb 6/29/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2008 67 Male 251 lb 6/29/2010 Consumer United States
Primary
Concomitant
Parosmia 1/1/2004 78 Female 180 lb 6/29/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 9/4/2009 69 Male 175 lb 6/29/2010 Consumer United States
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/2005 59 Female 223 lb 7/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertebroplasty Other Serious 4/19/2001 81 Male 165 lb 7/7/2010 United States
Primary
Concomitant
Myocardial Infarction Other Serious 7/31/2006 56 Male 214 lb 7/8/2010 Other Health Professional United States
Primary
Concomitant
Heart Rate Increased Hospitalization 5/29/2010 69 Male 7/13/2010 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious Male 170 lb 7/15/2010 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 74 Female 147 lb 7/16/2010 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 3/29/2010 65 Female 160 lb 7/16/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 39 Female 150 lb 7/16/2010 Consumer United States
Primary
Secondary
Concomitant
Rash 10/30/2007 48 Male 223 lb 7/16/2010 Consumer United States
Primary
Concomitant
Nervousness 11/20/2007 57 Male 271 lb 7/17/2010 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 48 Female 280 lb 7/21/2010 United States
Primary
Concomitant