Actos combined with Gemfibrozil

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Protein Urine Other Serious 8/1/2005 54 Male 190 lb 12/30/2005 Other Health Professional United States
Primary
Secondary
Concomitant
High Density Lipoprotein Decreased Other Serious 7/25/2005 57 Male 185 lb 1/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ischaemia Hospitalization 11/8/2005 59 Male 311 lb 1/30/2006 Physician United States
Primary
Concomitant
Fat Tissue Increased Hospitalization 12/15/2003 53 Female 1/25/2006 Netherlands
Primary
Concomitant
Cerebrovascular Accident Hospitalization 4/21/2004 58 Male 238 lb 4/13/2006 Lawyer United States
Primary
Concomitant
Fatigue Hospitalization 4/21/2004 58 Male 238 lb 5/1/2006 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 10/1/2005 59 Male 311 lb 5/16/2006 Physician United States
Primary
Concomitant
Therapeutic Response Unexpected 5/13/2006 63 Male 226 lb 7/19/2006 Consumer United States
Primary
Concomitant
Muscle Spasms Hospitalization 9/23/2006 52 Male 10/2/2006 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Chronic Required Intervention 1/1/2002 42 Male 250 lb 11/14/2006 United States
Primary
Concomitant
Skin Discolouration Required Intervention 1/1/2002 42 Male 250 lb 12/27/2006 Physician United States
Primary
Concomitant
Restlessness 5/5/2006 59 Male 220 lb 12/29/2006 Consumer United States
Primary
Concomitant
Sleep Disorder 47 Male 248 lb 11/1/2006 United States
Primary
Concomitant
Muscular Weakness Other Serious 1/1/2006 Male 200 lb 3/7/2007 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 1/29/2007 74 Male 230 lb 3/21/2007 United States
Primary
Secondary
Concomitant
Early Satiety 10/30/2006 68 Male 1/12/2007 Consumer United States
Primary
Concomitant
Malaise Other Serious 1/12/2007 62 Male 273 lb 4/23/2007 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 10/25/2006 54 Male 1/12/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/28/2006 Male 5/7/2007 Physician Australia
Primary
Secondary
Concomitant
Blood Bilirubin Increased Hospitalization 5/13/2007 Female 183 lb 5/14/2007 United States
Primary
Concomitant
Blood Bilirubin Increased Hospitalization 5/13/2007 Female 183 lb 5/16/2007 United States
Primary
Concomitant
Weight Decreased Hospitalization 5/13/2007 Female 183 lb 5/17/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/29/2007 67 Female 183 lb 5/17/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/29/2007 67 Female 183 lb 5/17/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/13/2007 67 Female 183 lb 5/22/2007 Physician United States
Primary
Concomitant
Malaise Other Serious 1/12/2007 62 Male 273 lb 6/8/2007 Other Health Professional United States
Primary
Concomitant
Asthenia Hospitalization 5/30/2007 54 Male 6/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 5/13/2007 Female 183 lb 6/12/2007 United States
Primary
Concomitant
Dizziness Hospitalization 5/30/2007 54 Male 207 lb 6/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting 1/1/2006 55 Male 7/11/2007 Consumer United States
Primary
Concomitant
Dysphagia 10/1/2006 9/21/2007 Consumer United States
Primary
Concomitant
Metabolic Acidosis Hospitalization 7/19/2007 60 Male 131 lb 10/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 1/1/2007 Male 316 lb 10/26/2007 Physician United States
Primary
Secondary
Concomitant
Throat Irritation 5/13/2007 68 Male 238 lb 5/17/2007 Consumer United States
Primary
Concomitant
Nausea Hospitalization 7/31/2007 60 Male 131 lb 3/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/31/2007 Male 131 lb 4/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Required Intervention 1/1/2007 73 Male 195 lb 7/7/2008 Consumer United States
Primary
Concomitant
Pathological Gambling Male 6/12/2008 United States
Primary
Concomitant
Suicidal Ideation 1/1/1999 Male 236 lb 7/17/2008 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased 9/1/2007 Male 7/25/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased Required Intervention 1/1/2007 73 195 lb 8/5/2008 Consumer United States
Primary
Concomitant
Weight Decreased 2/1/2008 60 Female 213 lb 7/7/2008 Consumer United States
Primary
Concomitant
Tooth Infection 5/9/2008 68 Male 7/7/2008 Consumer United States
Primary
Concomitant
Vision Blurred 1/1/2003 36 Female 226 lb 9/23/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 6/29/2007 58 Male 250 lb 1/22/2009 Consumer United States
Primary
Concomitant
Hallucination 66 Female 3/18/2009 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/20/2000 43 Female 291 lb 4/21/2009 United States
Primary
Concomitant
Pruritus 2/3/2009 Female 195 lb 5/27/2009 Consumer United States
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 6/1/2008 54 Male 285 lb 6/9/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2009 Female 172 lb 6/12/2009 Physician United States
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 11/1/2007 71 Female 142 lb 6/19/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/12/2000 53 Female 328 lb 7/7/2009 United States
Primary
Concomitant
Diabetes Mellitus Female 189 lb 7/22/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 7/1/2004 42 Male 189 lb 7/24/2009 United States
Primary
Concomitant
Hypoglycaemia Other Serious 4/2/2004 50 Male 208 lb 7/29/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/15/2007 51 Male 8/17/2009 United States
Primary
Concomitant
Flushing Male 270 lb 8/22/2009 United States
Primary
Concomitant
Flushing 5/30/2009 Male 8/22/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/14/2004 49 Female 178 lb 9/11/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2009 Female 172 lb 9/19/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/15/2007 51 Male 9/15/2009 United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 10/1/2003 26 Male 385 lb 9/23/2009 United States
Primary
Secondary
Concomitant
Diabetic Coma Other Serious 1/1/2002 40 Male 190 lb 9/23/2009 United States
Primary
Concomitant
Schizophrenia Hospitalization 1/1/2004 31 Female 200 lb 9/23/2009 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Required Intervention 8/1/2008 56 Male 200 lb 9/17/2009 Consumer United States
Primary
Concomitant
Ulcer 1/1/2005 51 Female 162 lb 9/23/2009 United States
Primary
Concomitant
Vision Blurred Required Intervention 8/1/2008 56 Male 200 lb 9/23/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 5/14/2002 60 Female 210 lb 10/15/2009 United States
Primary
Concomitant
Ill-defined Disorder Disability Female 215 lb 10/16/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 51 Male 10/15/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 51 Male 10/16/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 51 Male 11/4/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Male 260 lb 11/18/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 5/14/2002 60 Female 210 lb 11/26/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 51 Male 11/20/2009 United States
Primary
Concomitant
Anxiety 62 Female 256 lb 12/9/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 12/11/2009 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 1/13/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 77 Female 1/22/2010 United States
Primary
Concomitant
Stomatitis Hospitalization 11/19/2008 27 Female 471 lb 2/26/2010 Consumer United States
Primary
Concomitant
No Therapeutic Response Other Serious Male 246 lb 3/10/2010 Other Health Professional United States
Primary
Concomitant
Pancreatitis Hospitalization 3/15/2010 65 Male 187 lb 3/17/2010 Pharmacist United States
Primary
Concomitant
Renal Impairment Other Serious 11/6/2006 Male 246 lb 3/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 11/6/2006 69 Male 246 lb 4/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Injury Hospitalization 1/1/2006 38 Female 260 lb 6/23/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2008 67 Male 251 lb 6/29/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2003 36 Female 226 lb 7/7/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/14/2004 49 Female 178 lb 7/9/2010 United States
Primary
Concomitant
Cardiovascular Disorder Hospitalization 59 Male 285 lb 7/15/2010 Other Health Professional United States
Primary
Concomitant
Nervousness 11/20/2007 57 Male 271 lb 7/17/2010 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Required Intervention 64 Female 165 lb 7/27/2010 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 8/1/2009 73 Male 246 lb 7/28/2010 Consumer United States
Primary
Concomitant
Skin Exfoliation 1/1/2008 64 Male 196 lb 8/3/2010 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 59 Male 285 lb 8/23/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 58 Male 8/19/2010 United States
Primary
Concomitant
Feeling Hot 11/5/2009 66 Female 8/28/2010 United States
Primary
Concomitant
Sensory Disturbance 2/1/2010 61 Male 240 lb 8/28/2010 Other Health Professional United States
Primary
Concomitant
Cardiac Disorder Hospitalization 65 Male 9/1/2010 Consumer United States
Primary
Concomitant
Medication Residue 6/1/2009 82 Male 9/15/2010 Consumer United States
Primary
Concomitant
Leg Amputation Other Serious 9/1/2010 81 Male 198 lb 10/6/2010 Consumer United States
Primary
Concomitant
Renal Failure Other Serious Male 272 lb 10/5/2010 Consumer United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/21/2010 49 Female 324 lb 10/29/2010 Other Health Professional United States
Primary
Concomitant
Cough 71 Male 10/13/2010 Consumer United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 70 Male 10/21/2010 United States
Primary
Concomitant
Penile Erythema 60 Male 11/16/2010 Consumer United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/21/2010 49 Female 324 lb 11/8/2010 Other Health Professional United States
Primary
Concomitant
Product Quality Issue 65 Male 1/7/2011 Consumer United States
Primary
Concomitant
Anticonvulsant Drug Level Below Therapeutic 82 Female 174 lb 1/27/2011 Pharmacist United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/21/2010 49 Female 324 lb 1/28/2011 Other Health Professional United States
Primary
Concomitant
Muscle Spasms 6/1/2010 54 Male 260 lb 1/29/2011 Consumer United States
Primary
Concomitant
Renal Oncocytoma Hospitalization 1/1/2010 64 Male 210 lb 2/7/2011 Physician United States
Primary
Concomitant
Faeces Hard 9/1/2010 80 Male 2/10/2011 Consumer United States
Primary
Concomitant
Drug Ineffective 12/15/2010 76 Female 2/25/2011 Other Health Professional United States
Primary
Concomitant
Anxiety Other Serious 11/16/2006 85 Male 220 lb 3/8/2011 Consumer United States
Primary
Concomitant
Fear Other Serious 11/16/2006 85 Male 220 lb 3/8/2011 Consumer United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/21/2010 49 Female 324 lb 2/16/2011 Other Health Professional United States
Primary
Concomitant
Drug Ineffective 9/1/2010 80 Male 3/28/2011 Consumer United States
Primary
Concomitant
Erectile Dysfunction Hospitalization 46 Male 250 lb 3/22/2011 United States
Primary
Concomitant
Drug Ineffective 9/1/2010 80 Male 4/14/2011 Consumer United States
Primary
Concomitant
Herpes Zoster Hospitalization 1/1/2011 54 Female 220 lb 4/22/2011 Consumer United States
Primary
Concomitant
Unevaluable Event Other Serious 11/16/2006 85 Male 220 lb 5/18/2011 Lawyer United States
Primary
Concomitant
Pain Other Serious 11/16/2006 85 Male 220 lb 5/24/2011 Other Health Professional United States
Primary
Concomitant
Diarrhoea 1/23/2011 71 Female 195 lb 5/26/2011 Consumer United States
Primary
Concomitant
Leukopenia Other Serious 10/11/2010 62 Male 206 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Death Death 10/21/2010 37 Female 6/22/2011 Physician United States
Primary
Concomitant
Death Death 6/17/2011 87 Female 6/28/2011 Consumer United States
Primary
Concomitant
Off Label Use Other Serious Male 272 lb 5/20/2011 Lawyer United States
Primary
Concomitant
Death Death 6/17/2011 87 Female 7/12/2011 Consumer United States
Primary
Concomitant
Emotional Distress Other Serious 8/1/2007 70 Male 207 lb 7/12/2011 Physician United States
Primary
Secondary
Concomitant
Renal Disorder Other Serious Male 272 lb 7/25/2011 Consumer United States
Primary
Concomitant
Death Death 6/17/2011 87 Female 7/25/2011 Consumer United States
Primary
Concomitant
Hepatic Neoplasm Malignant Death 6/17/2011 87 Female 8/4/2011 Other Health Professional United States
Primary
Concomitant
Erythema 4/29/2011 60 Male 8/6/2011 Consumer United States
Primary
Concomitant
Diarrhoea Hospitalization 1/1/2006 38 Female 260 lb 8/15/2011 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2010 36 Male 380 lb 9/22/2011 Physician United States
Primary
Concomitant
Impaired Gastric Emptying Disability 7/9/2009 42 Female 10/3/2011 Physician United States
Primary
Concomitant
Nasal Congestion Other Serious 7/9/2009 42 Female 10/7/2011 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 3/10/2010 63 Female 223 lb 10/7/2011 United States
Primary
Secondary
Concomitant
Rhinorrhoea Hospitalization 7/9/2009 42 Female 10/20/2011 Physician United States
Primary
Concomitant
Nasal Congestion Hospitalization 7/9/2009 42 Female 11/23/2011 Lawyer United States
Primary
Concomitant
Drug Interaction Other Serious 10/1/2011 Female 12/5/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Nicotine Dependence Other Serious 1/1/2006 48 Female 220 lb 12/8/2011 Lawyer United States
Primary
Concomitant
Renal Failure Acute Other Serious 10/1/2011 Female 12/19/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Blood Cholesterol Decreased 64 Male 12/20/2011 Consumer United States
Primary
Concomitant
Rhinorrhoea Hospitalization 7/9/2009 42 Female 1/1/2012 Lawyer United States
Primary
Concomitant
Renal Disorder Other Serious 70 Male 272 lb 11/17/2011 Lawyer United States
Primary
Concomitant
Carcinoma In Situ Death 7/9/2009 42 Female 1/6/2012 Lawyer United States
Primary
Concomitant
Pruritus 5/6/2011 63 Male 1/28/2012 Consumer United States
Primary
Concomitant
Fatigue 4/22/2011 63 Male 1/28/2012 Consumer United States
Primary
Concomitant
Muscular Weakness 4/1/2011 63 Male 1/28/2012 Consumer United States
Primary
Concomitant

Drug Data