Actos combined with Fosamax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Decreased Hospitalization 12/1/2005 64 Female 350 lb 1/26/2006 Physician United States
Primary
Concomitant
Hip Fracture Hospitalization 1/1/2003 72 Female 3/2/2006 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 40 Female 3/3/2006 United States
Primary
Secondary
Concomitant
Weight Decreased 12/7/2005 63 Female 212 lb 3/20/2006 Physician United States
Primary
Concomitant
Overdose Other Serious 12/18/2000 71 Female 146 lb 4/4/2006 Lawyer United States
Primary
Concomitant
Syncope Hospitalization 2/20/2006 85 Female 4/6/2006 Physician United States
Primary
Secondary
Concomitant
Psychiatric Symptom Hospitalization 1/1/2003 59 Female 150 lb 4/14/2006 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/29/2000 71 Female 146 lb 4/19/2006 Physician Puerto Rico
Primary
Concomitant
Presenile Dementia Hospitalization 1/7/2003 59 Female 150 lb 5/1/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2006 53 Female 126 lb 6/8/2006 Physician United States
Primary
Concomitant
Pain 1/1/2006 64 Female 4/24/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2006 Female 251 lb 6/23/2006 Physician United States
Primary
Concomitant
Low Density Lipoprotein Increased Other Serious 5/2/2006 63 Male 184 lb 7/21/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2004 80 Female 200 lb 7/26/2006 United States
Primary
Secondary
Concomitant
Vasculitis Other Serious Female 8/29/2006 Physician United States
Primary
Secondary
Concomitant
Hypophosphataemia Hospitalization 8/8/2006 82 Male 128 lb 8/30/2006 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased 6/4/2006 68 Female 7/21/2006 Consumer United States
Primary
Concomitant
Hypophosphataemia Other Serious 8/8/2006 82 Male 128 lb 9/19/2006 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 151 lb 9/26/2006 Physician United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 3/1/2006 Female 11/3/2006 Physician United States
Primary
Concomitant
Fatigue Other Serious 2/1/2005 84 Female 8/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/9/2006 Female 134 lb 8/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 3/1/2005 68 Female 11/28/2006 United States
Primary
Concomitant
Skin Lesion Other Serious 1/1/2005 68 Female 298 lb 11/28/2006 Physician United States
Primary
Concomitant
Pain 1/1/2006 64 Female 10/23/2006 Physician United States
Primary
Concomitant
Troponin Increased Hospitalization 9/25/2002 66 Female 2/27/2007 Consumer United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 12/1/2006 60 Female 2/26/2007 Physician United States
Primary
Concomitant
Visual Acuity Reduced Required Intervention 1/1/2004 82 Female 197 lb 2/27/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 1/1/2006 58 Female 3/7/2007 Consumer United States
Primary
Concomitant
Proteinuria Life Threatening 3/1/2007 77 Female 137 lb 3/13/2007 Physician United States
Primary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Life Threatening 3/1/2007 77 Female 137 lb 3/27/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 1/28/2007 79 Male 3/29/2007 Physician United States
Primary
Secondary
Concomitant
Proteinuria Life Threatening 3/1/2007 77 Female 137 lb 4/5/2007 Physician United States
Primary
Concomitant
Weight Decreased 12/5/2006 68 Female 170 lb 1/12/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 Female 146 lb 4/23/2007 Consumer United States
Primary
Concomitant
Multiple Myeloma Life Threatening 3/1/2007 77 Female 137 lb 4/12/2007 Physician United States
Primary
Concomitant
Injection Site Haemorrhage 10/20/2006 69 Female 1/25/2007 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 6/1/2006 59 Female 5/10/2007 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2004 80 Female 200 lb 5/3/2007 Consumer United States
Primary
Secondary
Concomitant
Nausea 12/1/2006 52 Female 2/16/2007 United States
Primary
Concomitant
Vision Blurred Life Threatening 3/1/2007 78 Female 137 lb 5/8/2007 Physician United States
Primary
Secondary
Concomitant
Pruritus Other Serious 3/22/2007 74 Female 141 lb 5/10/2007 Other Health Professional United States
Primary
Concomitant
Blood Bilirubin Increased Hospitalization 5/13/2007 Female 183 lb 5/14/2007 United States
Primary
Concomitant
Blood Bilirubin Increased Hospitalization 5/13/2007 Female 183 lb 5/16/2007 United States
Primary
Concomitant
Weight Decreased Hospitalization 5/13/2007 Female 183 lb 5/17/2007 United States
Primary
Concomitant
Pyrexia Hospitalization 1/28/2007 79 Male 5/17/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/28/2007 79 Male 5/17/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/29/2007 67 Female 183 lb 5/17/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/13/2007 67 Female 183 lb 5/22/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 Female 146 lb 5/30/2007 Consumer United States
Primary
Concomitant
Unevaluable Event Life Threatening 3/1/2007 77 Female 137 lb 5/24/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased 3/6/2007 74 Male 319 lb 5/17/2007 Physician United States
Primary
Concomitant
Blood Glucose Fluctuation 3/21/2007 67 Female 5/17/2007 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 Female 146 lb 6/13/2007 Physician United States
Primary
Concomitant
Pain In Extremity 63 Female 195 lb 6/14/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/28/2007 Female 265 lb 6/12/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 5/13/2007 Female 183 lb 6/12/2007 United States
Primary
Concomitant
Weight Decreased 12/1/2006 72 Female 234 lb 4/10/2007 United States
Primary
Concomitant
Weight Decreased 71 Female 275 lb 4/10/2007 Consumer United States
Primary
Concomitant
Eye Haemorrhage Required Intervention 6/11/2003 83 Female 6/19/2007 Consumer United States
Primary
Concomitant
Tongue Black Hairy Other Serious 1/1/2000 63 Female 238 lb 8/7/2007 Other Health Professional United States
Primary
Concomitant
Urosepsis Other Serious 7/25/2007 57 Female 8/17/2007 Other Health Professional United States
Primary
Concomitant
Malaise Hospitalization 6/28/2007 76 Female 154 lb 8/17/2007 Physician France
Primary
Concomitant
Urosepsis Other Serious 7/25/2007 57 Female 8/21/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased 1/1/2006 68 Female 192 lb 7/11/2007 Consumer United States
Primary
Concomitant
Application Site Pruritus 9/1/2006 Female 8/27/2007 Consumer United States
Primary
Concomitant
Tongue Black Hairy Other Serious 10/29/1999 56 Female 238 lb 9/5/2007 Other Health Professional United States
Primary
Concomitant
Weight Increased 1/1/2006 59 Female 9/6/2007 Consumer United States
Primary
Concomitant
Skin Laceration 9/1/2007 Female 9/12/2007 Consumer United States
Primary
Concomitant
Restlessness Other Serious Female 170 lb 9/13/2007 Consumer United States
Primary
Concomitant
Upper Limb Fracture Other Serious 5/1/2006 68 Female 9/19/2007 Physician United States
Primary
Concomitant
Upper Limb Fracture Other Serious 5/1/2006 68 Female 9/20/2007 Physician United States
Primary
Concomitant
Dizziness 12/11/2006 77 Female 114 lb 8/16/2007 Physician United States
Primary
Concomitant
Haematemesis 6/11/2007 69 Female 8/16/2007 United States
Primary
Secondary
Concomitant
Malaise Hospitalization 6/28/2007 76 Female 154 lb 9/28/2007 Physician France
Primary
Concomitant
Venous Thrombosis Limb Other Serious 10/29/1999 56 Female 238 lb 10/11/2007 Other Health Professional United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 58 Female 132 lb 10/22/2007 Physician United States
Primary
Concomitant
Weight Decreased 7/1/2007 78 Female 397 lb 10/8/2007 Consumer United States
Primary
Concomitant
Vomiting 1/1/2007 72 Female 186 lb 10/9/2007 Consumer United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 58 Female 132 lb 12/18/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 10/11/2002 68 Female 11/28/2007 United States
Primary
Concomitant
Osteonecrosis Other Serious 3/1/2007 53 Female 250 lb 11/28/2007 Other Health Professional United States
Primary
Concomitant
Vision Blurred Hospitalization 8/28/2005 Male 182 lb 1/11/2008 Consumer United States
Primary
Concomitant
Anosmia Disability 2/16/2007 50 Female 12/26/2007 United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 57 Female 132 lb 1/24/2008 Physician United States
Primary
Concomitant
Insomnia 10/1/2007 Male 1/31/2008 Consumer United States
Primary
Concomitant
Venous Thrombosis Limb Other Serious 10/29/1999 56 Female 238 lb 2/4/2008 Other Health Professional United States
Primary
Concomitant
Venous Thrombosis Limb Other Serious 10/29/1999 56 Female 238 lb 2/18/2008 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Required Intervention 1/24/2007 77 Female 1/16/2008 Other Health Professional United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 57 Female 132 lb 2/28/2008 Physician United States
Primary
Concomitant
Viral Upper Respiratory Tract Infection Other Serious 3/1/2008 Female 181 lb 4/10/2008 Consumer United States
Primary
Concomitant
Diarrhoea Hospitalization 4/1/2008 Female 4/25/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 239 lb 4/25/2008 Consumer United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 8/1/2003 73 Female 5/6/2008 Physician United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 8/1/2003 73 Female 5/9/2008 Physician United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 8/1/2003 73 Female 203 lb 7/1/2008 Physician United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 8/1/2003 73 Female 203 lb 7/21/2008 Physician United States
Primary
Secondary
Concomitant
Upper Limb Fracture Other Serious 5/1/2006 68 Female 7/24/2008 Physician United States
Primary
Concomitant
Chest Discomfort Female 7/24/2008 Consumer United States
Primary
Concomitant
Gastric Varices Hospitalization 7/7/2008 Male 7/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Visual Impairment Required Intervention 8/20/2003 71 Female 168 lb 7/21/2008 Physician United States
Primary
Concomitant
Venous Thrombosis Limb Other Serious 10/29/1999 56 Female 238 lb 8/11/2008 Other Health Professional United States
Primary
Concomitant
Gastric Varices Hospitalization 7/7/2008 Male 8/26/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Varices Hospitalization 7/7/2008 Male 9/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Thyroid Neoplasm Other Serious 8/1/2003 73 Female 203 lb 10/9/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2006 Female 185 lb 10/9/2008 Physician United States
Primary
Concomitant
Gastric Varices Hospitalization 7/7/2008 Male 10/14/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2006 Female 185 lb 11/4/2008 Physician United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 8/1/2003 73 Female 203 lb 12/3/2008 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 10/1/2002 36 Female 276 lb 12/5/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 10/11/2002 66 Female 312 lb 11/26/2008 United States
Primary
Concomitant
Hypoglycaemia Hospitalization 11/29/2008 71 Female 12/15/2008 Pharmacist United States
Primary
Concomitant
Malaise Hospitalization 6/28/2007 76 Female 154 lb 1/30/2009 Physician France
Primary
Concomitant
Malaise Hospitalization 6/28/2007 76 Female 154 lb 2/2/2009 Physician France
Primary
Concomitant
Respiratory Disorder Other Serious 1/17/2009 55 Female 2/11/2009 Consumer France
Primary
Secondary
Concomitant
Wheezing Hospitalization 12/1/2008 85 Female 3/19/2009 Physician United States
Primary
Concomitant
Benign Breast Neoplasm Other Serious 1/1/2006 Female 170 lb 4/9/2009 Consumer United States
Primary
Secondary
Concomitant
Precancerous Cells Present Other Serious Female 180 lb 4/30/2009 Consumer United States
Primary
Concomitant
Pharyngeal Oedema 5/10/2008 77 Female 173 lb 5/15/2009 Physician United States
Primary
Concomitant
Overdose Hospitalization 1/1/2006 73 Female 5/28/2009 Consumer United States
Primary
Concomitant
Rectal Cancer Other Serious 3/13/2009 Female 146 lb 5/29/2009 Physician United States
Primary
Secondary
Concomitant
Insulin-requiring Type 2 Diabetes Mellitus Other Serious 4/29/2002 50 Female 388 lb 6/1/2009 United States
Primary
Concomitant
Rectal Cancer Other Serious 3/13/2009 Female 146 lb 6/8/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/1/2009 Female 172 lb 6/12/2009 Physician United States
Primary
Concomitant
Necrotising Retinitis Other Serious 9/1/2008 Female 114 lb 6/17/2009 Physician United States
Primary
Concomitant
Aplasia Pure Red Cell Hospitalization 3/3/2009 Male 6/19/2009 Physician Japan
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 10/1/2002 36 Female 276 lb 6/26/2009 United States
Primary
Concomitant
Aplasia Pure Red Cell Life Threatening 3/3/2009 Male 6/30/2009 Physician Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 1/1/1999 40 Female 134 lb 7/16/2009 United States
Primary
Concomitant
Urinary Retention Hospitalization 6/1/2009 64 Male 7/21/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 12/18/2008 68 Male 168 lb 8/6/2009 Physician United States
Primary
Concomitant
Pruritus Generalised 12/10/2008 Female 140 lb 8/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Flushing 7/1/2008 Male 8/22/2009 United States
Primary
Concomitant
No Adverse Event 5/8/2009 74 Female 129 lb 8/14/2009 Other Health Professional United States
Primary
Concomitant
Torsade De Pointes Hospitalization 7/23/2009 83 Female 203 lb 8/31/2009 Physician Switzerland
Primary
Secondary
Concomitant
Venous Thrombosis Limb Other Serious 10/29/1999 56 Female 238 lb 9/1/2009 Other Health Professional United States
Primary
Concomitant
Torsade De Pointes Hospitalization 7/23/2009 83 Female 9/3/2009 Switzerland
Primary
Secondary
Concomitant
Dysuria Hospitalization 6/1/2009 64 Male 139 lb 9/17/2009 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 3/1/2009 Female 172 lb 9/19/2009 Physician United States
Primary
Concomitant
Torticollis 10/31/2003 52 Female 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious Female 223 lb 9/23/2009 United States
Primary
Concomitant
Nerve Compression 1/1/2008 78 Female 195 lb 10/2/2009 United States
Primary
Concomitant
Vomiting Hospitalization 12/18/2008 68 Male 168 lb 10/8/2009 Physician United States
Primary
Concomitant
Dysuria Hospitalization 6/3/2009 64 Male 139 lb 10/21/2009 Physician Japan
Primary
Concomitant
Venous Thrombosis Limb Other Serious 10/29/1999 56 Female 238 lb 11/24/2009 Other Health Professional United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 5/31/2006 60 Female 11/25/2009 United States
Primary
Secondary
Concomitant
Venous Thrombosis Limb Other Serious 10/29/1999 56 Female 238 lb 12/18/2009 Other Health Professional United States
Primary
Concomitant
Pancreatic Carcinoma Hospitalization 1/1/2007 Female 1/15/2010 Physician United States
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/2006 60 Female 3/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 10/2/2008 28 Female 112 lb 3/4/2010 Physician Japan
Primary
Secondary
Concomitant

Drug Data