Actos combined with Digoxin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Fibrillation Death 10/15/2005 76 Male 1/5/2006 Physician Japan
Primary
Concomitant
Vision Blurred Required Intervention 10/1/2002 68 Female 130 lb 1/17/2006 United States
Primary
Concomitant
Death Other Serious 12/25/2004 74 Male 1/20/2006 Pharmacist United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2003 66 Male 231 lb 2/16/2006 Lawyer United States
Primary
Concomitant
Prescribed Overdose Other Serious 1/1/1999 71 Female 146 lb 2/17/2006 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 1/26/2006 72 Male 2/16/2006 Physician United States
Primary
Concomitant
Blood Glucose Increased 1/1/2006 Male 2/27/2006 Consumer United States
Primary
Concomitant
Overdose Other Serious 12/18/2000 71 Female 146 lb 4/4/2006 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 78 Male 4/5/2006 France
Primary
Concomitant
Urinary Tract Infection Other Serious 5/29/2000 71 Female 146 lb 4/19/2006 Physician Puerto Rico
Primary
Concomitant
Orthostatic Hypotension Other Serious 3/1/2006 78 Male 5/1/2006 Consumer United States
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 3/24/2003 63 Male 298 lb 5/11/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased 5/11/2005 90 Male 205 lb 5/30/2006 Consumer United States
Primary
Concomitant
Orthostatic Hypotension Other Serious 3/1/2006 78 Male 5/31/2006 Consumer United States
Primary
Secondary
Concomitant
Coma Other Serious 5/1/2005 75 Male 7/19/2006 Consumer United States
Primary
Concomitant
Renal Disorder Other Serious 7/1/2006 Male 7/31/2006 Pharmacist United States
Primary
Concomitant
Fatigue Male 8/1/2006 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 4/1/2006 85 Female 208 lb 7/31/2006 United States
Primary
Concomitant
Medication Residue Other Serious 1/1/2002 72 Female 128 lb 8/4/2006 United States
Primary
Concomitant
Pharmaceutical Product Complaint 1/1/2002 72 Female 128 lb 8/14/2006 United States
Primary
Concomitant
Orthostatic Hypotension Other Serious 3/1/2006 78 Male 8/18/2006 Physician United States
Primary
Secondary
Concomitant
Renal Disorder Other Serious 7/1/2006 Male 284 lb 8/29/2006 Pharmacist United States
Primary
Concomitant
Streptococcal Infection Hospitalization 10/8/2005 66 Female 163 lb 8/18/2006 Other Health Professional United States
Primary
Concomitant
Streptococcal Infection Hospitalization 10/8/2005 66 Female 163 lb 9/12/2006 Other Health Professional United States
Primary
Concomitant
Injection Site Pain 3/1/2006 49 Female 280 lb 7/19/2006 Consumer United States
Primary
Concomitant
Streptococcal Infection Hospitalization 10/8/2005 66 Female 9/13/2006 United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2006 Female 11/3/2006 Physician United States
Primary
Secondary
Concomitant
Skin Lesion Hospitalization 6/1/2004 76 Male 200 lb 8/29/2006 Physician United States
Primary
Concomitant
Muscle Rigidity 55 Male 11/13/2006 Other Health Professional United States
Primary
Concomitant
Chest Pain Hospitalization 11/9/2006 50 Male 11/17/2006 United States
Primary
Concomitant
Fatigue Male 11/28/2006 Consumer United States
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 11/1/2006 50 Male 12/7/2006 United States
Primary
Concomitant
Systemic Lupus Erythematosus Hospitalization 8/26/2006 77 Male 130 lb 10/26/2006 Pharmacist United States
Primary
Concomitant
Swelling Death Male 2/20/2007 United States
Primary
Concomitant
Blood Glucose Increased Other Serious 1/1/2007 Male 206 lb 3/20/2007 Consumer United States
Primary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 1/1/2007 Male 206 lb 4/18/2007 Physician United States
Primary
Concomitant
Wound Other Serious 3/1/2006 80 Female 4/26/2007 Pharmacist Brazil
Primary
Secondary
Concomitant
Pemphigus Other Serious 3/1/2006 80 Female 4/26/2007 Pharmacist Brazil
Primary
Secondary
Concomitant
Polyp 12/11/2006 80 Male 225 lb 4/30/2007 Consumer United States
Primary
Concomitant
Oedema Other Serious 68 Female 5/2/2007 Korea, Republic Of
Primary
Concomitant
Weight Increased Hospitalization 1/1/2007 62 Female 290 lb 5/10/2007 Consumer United States
Primary
Concomitant
Diverticulitis Life Threatening 4/24/2007 Male 173 lb 5/15/2007 Physician United States
Primary
Secondary
Concomitant
Diverticulitis Life Threatening 4/24/2007 Male 173 lb 5/24/2007 Physician United States
Primary
Secondary
Concomitant
Vitamin D Decreased Required Intervention 5/29/2006 71 Female 141 lb 2/7/2007 Physician United States
Primary
Concomitant
Diverticulitis Life Threatening 4/24/2007 Male 173 lb 5/31/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting 10/27/2006 81 Female 143 lb 5/17/2007 Physician United States
Primary
Concomitant
Renal Impairment Other Serious 5/2/2007 Female 200 lb 6/12/2007 Consumer United States
Primary
Concomitant
Blood Urea Increased 1/31/2007 50 Female 4/10/2007 Physician United States
Primary
Concomitant
Diverticulitis Life Threatening 4/24/2007 Male 173 lb 6/20/2007 Physician United States
Primary
Secondary
Concomitant
Cardiac Flutter Other Serious 3/1/2003 68 Female 6/21/2007 Consumer United States
Primary
Secondary
Concomitant
Tendon Injury Hospitalization 3/12/2007 60 Male 6/19/2007 Consumer United States
Primary
Concomitant
Sudden Death Death 10/10/2003 61 Female 7/16/2007 Korea, Republic Of
Primary
Concomitant
Weight Increased Hospitalization 7/2/2007 65 Male 7/24/2007 Japan
Primary
Concomitant
Multiple Fractures Hospitalization 1/1/2005 Female 7/25/2007 Australia
Primary
Concomitant
Drug Ineffective Other Serious 3/1/2003 68 Female 8/31/2007 Consumer United States
Primary
Secondary
Concomitant
Injection Site Haemorrhage 4/30/2007 73 Male 7/11/2007 Consumer United States
Primary
Concomitant
Sinusitis 3/1/2007 60 Female 7/11/2007 Consumer United States
Primary
Concomitant
Atrial Fibrillation Other Serious 12/30/2003 68 Female 9/7/2007 Korea, Republic Of
Primary
Concomitant
Pancreatic Disorder Life Threatening 83 Male 216 lb 9/24/2007 Physician United States
Primary
Secondary
Concomitant
Liver Tenderness Required Intervention Female 144 lb 9/18/2007 Physician United States
Primary
Concomitant
Abdominal Pain 73 Male 11/16/2007 Consumer United States
Primary
Concomitant
Peritonitis Other Serious 10/1/2006 64 Female 216 lb 10/22/2007 Other Health Professional United States
Primary
Concomitant
Pancreatitis Hospitalization 1/1/2007 Male 12/17/2007 Physician United States
Primary
Concomitant
Mixed Receptive-expressive Language Disorder Other Serious 9/3/2007 74 Female 12/11/2007 United Kingdom
Primary
Concomitant
Mixed Receptive-expressive Language Disorder Required Intervention 9/3/2007 74 Female 12/17/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 12/18/2007 48 Female 12/28/2007 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased 5/23/2007 66 Male 10/8/2007 Consumer United States
Primary
Concomitant
Hypertension Other Serious Female 1/1/2008 Consumer United States
Primary
Concomitant
Dysarthria Life Threatening 11/6/2007 71 Female 155 lb 1/7/2008 Pharmacist United States
Primary
Concomitant
Pancreatitis Hospitalization 1/1/2007 Male 3/3/2008 Physician United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 4/23/2007 81 Male 161 lb 4/24/2007 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 6/29/2007 Male 3/13/2008 Physician United States
Primary
Concomitant
Death Hospitalization 2/27/2008 Female 140 lb 3/14/2008 Pharmacist United States
Primary
Concomitant
Tremor Other Serious 12/18/2007 Female 212 lb 3/17/2008 Consumer United States
Primary
Secondary
Concomitant
Angioedema Other Serious 2/21/2008 Female 140 lb 3/19/2008 Pharmacist United States
Primary
Concomitant
Hypomagnesaemia Other Serious 2/20/2007 69 Male 3/28/2008 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 10/2/2007 69 Male 200 lb 3/31/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 10/2/2007 69 Male 200 lb 4/9/2008 Physician Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 10/2/2007 69 Male 200 lb 4/18/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Syncope Other Serious 5/1/2008 75 Male 5/19/2008 United States
Primary
Concomitant
Vertigo Hospitalization 4/2/2008 61 Female 5/19/2008 Consumer United States
Primary
Concomitant
Vomiting Death 1/16/2008 60 Male 200 lb 5/28/2008 United States
Primary
Concomitant
Pruritus Generalised Disability 1/1/2007 85 Male 6/11/2008 Consumer United States
Primary
Concomitant
Tremor 1/1/2007 72 Female 220 lb 4/10/2008 Consumer United States
Primary
Concomitant
Hypotension Required Intervention 1/25/2008 56 Male 245 lb 6/16/2008 United States
Primary
Concomitant
Vomiting Hospitalization 4/21/2008 63 Male 193 lb 6/26/2008 United States
Primary
Concomitant
Parotitis Hospitalization 7/6/2006 Male 146 lb 7/2/2008 United States
Primary
Concomitant
Renal Impairment Hospitalization 4/3/2008 89 Male 130 lb 6/28/2008 Pharmacist United States
Primary
Concomitant
Syncope Other Serious 4/24/2008 75 Male 150 lb 7/16/2008 United States
Primary
Concomitant
Tremor 1/1/2007 72 Female 7/7/2008 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Life Threatening 2/20/2008 77 Male 226 lb 8/15/2008 United States
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased 4/22/2008 Male 8/15/2008 Physician United States
Primary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 12/20/2007 79 Female 207 lb 8/22/2008 United States
Primary
Concomitant
Vomiting Hospitalization 7/24/2007 66 Female 150 lb 8/28/2008 Consumer United States
Primary
Concomitant
Joint Swelling Hospitalization 6/1/2008 79 Male 250 lb 9/17/2008 Consumer United States
Primary
Concomitant
Throat Tightness Hospitalization 4/30/2007 79 Female 207 lb 10/10/2008 United States
Primary
Concomitant
Swollen Tongue Life Threatening 9/30/2008 72 Male 10/17/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 9/30/2008 72 Male 10/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tooth Infection Life Threatening 9/30/2008 72 Male 10/27/2008
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 9/30/2008 72 Male 11/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 11/29/2008 71 Female 12/15/2008 Pharmacist United States
Primary
Concomitant
Renal Impairment Hospitalization 1/1/2007 Male 190 lb 12/11/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 4/30/2008 71 Female 200 lb 12/12/2008 United States
Primary
Concomitant
Prothrombin Level Increased Other Serious 4/15/2008 65 Female 278 lb 1/6/2009 Pharmacist United States
Primary
Secondary
Concomitant
Memory Impairment Other Serious 1/1/1997 Female 200 lb 1/15/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased Other Serious 12/15/2008 88 Female 1/26/2009 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Pneumococcal Hospitalization 10/2/2007 Male 200 lb 2/9/2009 Canada
Primary
Secondary
Concomitant
Vascular Graft Hospitalization 6/1/2008 79 Male 250 lb 2/9/2009 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 10/1/2007 Female 135 lb 2/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 6/11/2006 65 Male 209 lb 2/23/2009 Physician Germany
Primary
Concomitant
Interacting
Ventricular Tachycardia Hospitalization 60 Female 135 lb 3/4/2009 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/13/2008 Male 225 lb 3/11/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 60 Female 135 lb 3/12/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Required Intervention 9/14/2008 73 Female 160 lb 3/10/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 60 Female 135 lb 4/3/2009 United States
Primary
Concomitant
Toothache Hospitalization 71 Female 4/15/2009 United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 8/1/2005 67 Male 4/27/2009 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 4/1/2005 56 Female 190 lb 5/6/2009 Consumer United States
Primary
Concomitant
Tremor Death 2/15/2009 90 Female 5/6/2009 United States
Primary
Concomitant
Cataract Other Serious 5/1/2007 Female 5/18/2009 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 5/12/1994 60 Female 5/15/2009 Lawyer United States
Primary
Concomitant
Product Quality Issue 57 Male 5/26/2009 Pharmacist United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 73 Female 5/24/2009 United States
Primary
Concomitant
Renal Failure Life Threatening 57 Female 6/17/2009 United States
Primary
Concomitant
Unevaluable Event Life Threatening 57 Female 7/1/2009 Lawyer United States
Primary
Concomitant
Renal Failure Chronic Other Serious 5/21/2000 46 Male 260 lb 7/10/2009 United States
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 5/26/2009 77 Male 7/9/2009 Germany
Primary
Concomitant
Unresponsive To Stimuli Death Female 150 lb 7/17/2009 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Other Serious 4/14/2009 67 Female 7/14/2009 United Kingdom
Primary
Concomitant
Trigger Finger Other Serious 5/1/2007 Female 7/20/2009 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 73 Female 7/16/2009 United States
Primary
Concomitant
Pain Hospitalization 66 Female 7/15/2009 United States
Primary
Concomitant
Visual Field Defect Hospitalization 61 Female 7/21/2009 United States
Primary
Concomitant
Weight Increased Life Threatening 57 Female 7/21/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Death Female 150 lb 7/29/2009 Other Health Professional United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 65 Male 7/27/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Hospitalization 66 Female 7/22/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 72 Female 7/22/2009 United States
Primary
Concomitant
Pain Death 1/22/2008 57 Male 7/30/2009 Lawyer United States
Primary
Concomitant
Weight Increased Life Threatening 57 Female 8/3/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/19/2005 85 Male 165 lb 8/12/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 66 Female 8/6/2009 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/26/2000 58 Female 293 lb 8/14/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 8/10/2009 United States
Primary
Concomitant
Visual Field Defect Hospitalization 61 Female 237 lb 8/10/2009 United States
Primary
Concomitant
Visual Field Defect Hospitalization 61 Female 237 lb 8/4/2009 United States
Primary
Concomitant
Weight Increased Life Threatening 57 Female 8/11/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 6/1/2009 Male 8/19/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 61 Female 8/16/2009 Lawyer United States
Primary
Concomitant

Drug Data