Actos combined with Carvedilol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Decreased Required Intervention 11/1/2005 76 Female 2/7/2006 Physician United States
Primary
Secondary
Concomitant
Hepatotoxicity Death 2/15/2006 60 Male 5/22/2006 Germany
Primary
Concomitant
Pyrexia Hospitalization 3/31/2006 Female 5/26/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/31/2006 Female 6/7/2006 Physician Japan
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 7/1/2006 59 Male 7/14/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Death 2/15/2006 60 Male 11/6/2006 Germany
Primary
Concomitant
Urinary Incontinence Hospitalization 7/1/2006 59 Male 12/26/2006 Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 10/1/2006 63 Male 4/25/2007 Austria
Primary
Concomitant
Proteinuria Hospitalization 10/15/2003 5 Male 4/26/2007 Korea, Republic Of
Primary
Concomitant
Urinary Retention Hospitalization 5/1/2007 60 Male 204 lb 5/11/2007 Physician Germany
Primary
Concomitant
Renal Impairment Hospitalization 10/15/2003 61 Male 5/24/2007 Korea, Republic Of
Primary
Concomitant
Urinary Retention Hospitalization 5/1/2007 60 Male 204 lb 6/6/2007 Other Health Professional Germany
Primary
Concomitant
Renal Impairment Hospitalization 10/15/2003 5 Male 6/8/2007 Korea, Republic Of
Primary
Concomitant
Sudden Death Death 10/10/2003 61 Female 7/16/2007 Korea, Republic Of
Primary
Concomitant
Urinary Retention Hospitalization 5/1/2007 60 Male 204 lb 7/13/2007 Other Health Professional Germany
Primary
Concomitant
Urinary Retention Hospitalization 5/1/2007 60 Male 204 lb 7/13/2007 Other Health Professional Germany
Primary
Concomitant
Renal Impairment Hospitalization 10/15/2003 61 Male 7/31/2007 Korea, Republic Of
Primary
Concomitant
Urinary Retention Hospitalization 5/1/2007 60 Male 204 lb 8/10/2007 Other Health Professional Germany
Primary
Concomitant
Torsade De Pointes Hospitalization 7/20/2007 74 Female 250 lb 8/13/2007 Physician United States
Primary
Secondary
Concomitant
Pancytopenia 6/18/2007 67 Female 10/22/2007 Japan
Primary
Concomitant
Urinary Retention Hospitalization 5/1/2007 60 Male 204 lb 11/12/2007 Germany
Primary
Concomitant
Proctitis Haemorrhagic Other Serious 8/20/2007 62 Male 11/28/2007 Germany
Primary
Concomitant
Respiratory Tract Infection Hospitalization 9/1/2006 57 Female 2/12/2008 Consumer United States
Primary
Concomitant
Weight Increased 8/27/2007 72 Female 2/13/2008 Consumer United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 5/1/2007 60 Male 204 lb 3/17/2008 Physician Germany
Primary
Concomitant
Verbal Abuse Other Serious 3/20/2008 Female 200 lb 4/2/2008 United States
Primary
Concomitant
Osteolysis Hospitalization 3/27/2007 63 Male 4/29/2008 Italy
Primary
Concomitant
Ventricular Tachycardia Life Threatening 4/19/2008 72 Female 119 lb 6/5/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/25/2008 66 Male 6/20/2008 Consumer Japan
Primary
Secondary
Concomitant
Chromaturia 7/31/2008 Female 8/21/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 7/25/2008 72 Male 9/29/2008 Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/25/2008 72 Male 10/1/2008 Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 7/26/2006 Female 10/17/2008 Physician United States
Primary
Secondary
Concomitant
Photophobia 3/1/2008 Female 11/13/2008 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Hospitalization 1/1/2007 Female 220 lb 11/13/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral 9/1/2008 70 Female 11/14/2008 United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 7/1/2008 Male 11/14/2008 United States
Primary
Concomitant
Gastritis Hospitalization 7/26/2006 Female 12/10/2008 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 1/1/2007 Male 190 lb 12/11/2008 Consumer United States
Primary
Concomitant
Urine Output Decreased Other Serious 11/12/2008 Male 200 lb 12/23/2008 Consumer United States
Primary
Concomitant
Macular Degeneration Other Serious 1/1/2007 Female 220 lb 1/27/2009 Physician United States
Primary
Concomitant
Pericardial Effusion Hospitalization 12/10/2008 70 Female 1/26/2009 Japan
Primary
Concomitant
Blood Potassium Increased 71 Female 190 lb 2/18/2009 Consumer United States
Primary
Concomitant
Pruritus Female 2/24/2009 United States
Primary
Concomitant
Oedema Peripheral 9/1/2008 70 Female 183 lb 2/16/2009 United States
Primary
Secondary
Concomitant
Gastritis Hospitalization 7/26/2006 Female 3/4/2009 Physician United States
Primary
Concomitant
Dyspnoea 3/21/2009 Male 4/7/2009 Consumer
Primary
Concomitant
Skin Ulcer Other Serious 1/27/2009 76 Male 4/27/2009 United States
Primary
Concomitant
Tremor Death 2/15/2009 90 Female 5/6/2009 United States
Primary
Concomitant
Dyspnoea 3/21/2009 Male 5/20/2009 Consumer
Primary
Concomitant
Rash Pruritic Female 5/27/2009 United States
Primary
Concomitant
Blood Glucose Increased Male 260 lb 5/27/2009 United States
Primary
Concomitant
Renal Impairment Life Threatening 4/8/2009 84 Male 132 lb 5/27/2009 Japan
Primary
Secondary
Concomitant
Osteoporosis Required Intervention 7/1/2008 29 Female 6/22/2009 Germany
Primary
Concomitant
Intentional Overdose Required Intervention 4/10/2009 61 Male 6/5/2009 Pharmacist United States
Primary
Secondary
Concomitant
Nausea Other Serious 6/15/2009 7/17/2009 Pharmacist Japan
Primary
Concomitant
Pleural Effusion Other Serious 4/14/2009 67 Female 7/14/2009 United Kingdom
Primary
Concomitant
Hyperkalaemia Life Threatening 4/8/2009 Male 7/17/2009 Japan
Primary
Secondary
Hyperkalaemia Life Threatening 4/8/2009 84 Male 7/21/2009 Japan
Primary
Secondary
Dyspnoea Exertional Hospitalization 7/18/2009 Female 212 lb 7/29/2009 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 72 Female 7/22/2009 United States
Primary
Concomitant
Pain Death 1/22/2008 57 Male 7/30/2009 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 7/17/2009 58 Female 8/20/2009 Consumer United States
Primary
Concomitant
Dyspnoea Exertional Hospitalization 7/18/2009 Female 212 lb 8/21/2009 Physician United States
Primary
Secondary
Concomitant
Blood Glucose Increased 4/2/2009 Male 8/22/2009 United States
Primary
Concomitant
Flushing 3/15/2009 Male 8/22/2009 United States
Primary
Concomitant
Wheezing Hospitalization 65 Female 8/20/2009 United States
Primary
Concomitant
Social Problem Hospitalization 1/20/2006 73 Male 163 lb 9/15/2009 United States
Primary
Concomitant
Weight Increased 12/1/2000 50 Male 275 lb 9/23/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/1/2009 Male 170 lb 9/25/2009 United States
Primary
Concomitant
Vomiting Hospitalization 1/22/2008 46 Male 9/21/2009 Lawyer United States
Primary
Concomitant
Vision Blurred Other Serious 67 Female 326 lb 2/3/2009 United States
Primary
Concomitant
Unemployment Hospitalization 1/20/2006 73 Male 163 lb 9/22/2009 United States
Primary
Concomitant
Ventricular Fibrillation Death 1/22/2008 57 Male 10/9/2009 United States
Primary
Concomitant
Ventricular Fibrillation Death 1/22/2008 57 Male 10/16/2009 United States
Primary
Concomitant
Wheezing Hospitalization 65 Female 10/16/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 65 Female 10/22/2009 Consumer United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 1/22/2008 57 Male 11/4/2009 United States
Primary
Concomitant
Skin Ulcer Other Serious 1/27/2009 76 Male 11/16/2009 United States
Primary
Concomitant
Blood Glucose Increased Male 234 lb 11/25/2009 United States
Primary
Concomitant
Vomiting Hospitalization 1/22/2008 57 Male 11/16/2009 United States
Primary
Concomitant
X-ray Limb Abnormal Other Serious 72 Male 11/16/2009 United States
Primary
Concomitant
Vision Blurred Hospitalization 72 Male 11/20/2009 United States
Primary
Concomitant
Vomiting Hospitalization 1/22/2008 57 Male 11/20/2009 United States
Primary
Concomitant
Dyspnoea Exertional Hospitalization 7/18/2009 Female 212 lb 12/9/2009 Physician United States
Primary
Secondary
Concomitant
Sinusitis 1/1/2009 Male 12/16/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 12/11/2009 United States
Primary
Concomitant
Dyspnoea Exertional Hospitalization 7/18/2009 Female 212 lb 12/18/2009 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 73 Female 12/23/2009 Lawyer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 11/2/2009 65 Male 146 lb 1/5/2010 Japan
Primary
Secondary
Concomitant
Dyspnoea Exertional Hospitalization 7/18/2009 Female 212 lb 1/8/2010 Physician United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/6/2010 46 Male 476 lb 1/8/2010 Pharmacist United States
Primary
Concomitant
Macular Degeneration Other Serious 1/1/2009 Female 190 lb 1/18/2010 Consumer United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 1/22/2008 57 Male 1/7/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 72 Male 201 lb 1/11/2010 United States
Primary
Concomitant
Sleep Disorder Life Threatening 10/1/2009 48 Male 353 lb 1/22/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 1/13/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 72 Male 201 lb 1/20/2010 United States
Primary
Concomitant
Dialysis Other Serious Male 190 lb 2/2/2010 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 66 Female 234 lb 1/27/2010 United States
Primary
Concomitant
Myocardial Infarction Death 12/24/2009 Female 275 lb 2/18/2010 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased Male 190 lb 3/1/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 7/1/2008 Male 162 lb 3/8/2010 Physician United States
Primary
Concomitant
Renal Impairment Life Threatening 9/10/2008 79 Female 3/26/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious Male 190 lb 3/26/2010 Consumer United States
Primary
Concomitant
Blood Glucose Increased Other Serious 1/1/2010 Female 3/24/2010 Other Health Professional United States
Primary
Concomitant
Hyperkeratosis 1/1/2009 Female 190 lb 3/30/2010 Physician United States
Primary
Concomitant
Malaise Hospitalization 3/21/2010 80 Female 3/29/2010 Consumer Canada
Primary
Concomitant
Weight Decreased Hospitalization 58 Male 4/6/2010 Lawyer United States
Primary
Concomitant
Skin Ulcer Other Serious 1/27/2009 76 Male 5/10/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 66 Female 234 lb 5/6/2010 United States
Primary
Concomitant
Thrombosis Death 12/23/2009 27 Female 275 lb 5/12/2010 Physician United States
Primary
Concomitant
Speech Disorder Hospitalization 1/1/2010 80 Female 5/13/2010 Consumer Canada
Primary
Concomitant
Pneumonia Hospitalization 1/9/2010 71 Male 5/21/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Hospitalization 1/22/2008 57 Male 5/21/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 79 Male 142 lb 5/26/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 73 Female 5/28/2010 United States
Primary
Concomitant
Hyperkalaemia Other Serious 9/7/2009 72 Male 6/2/2010 Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 66 Female 234 lb 6/3/2010 United States
Primary
Concomitant
Paraesthesia 1/1/2009 65 Male 145 lb 6/29/2010 Pharmacist United States
Primary
Concomitant
Abdominal Discomfort 10/1/2009 58 Male 245 lb 7/1/2010 Consumer United States
Primary
Concomitant
Speech Disorder Hospitalization 1/1/2010 80 Female 6/30/2010 Physician Canada
Primary
Concomitant
Weight Increased Hospitalization 1/22/2008 57 Male 7/19/2010 United States
Primary
Concomitant
Vomiting Other Serious 8/2/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 7/9/2010 8/6/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 3/16/2010 77 Female 8/12/2010 Physician United States
Primary
Concomitant
Syncope Other Serious 79 Male 261 lb 8/20/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2007 40 Female 174 lb 8/26/2010 Lawyer United States
Primary
Concomitant
Pain Male 240 lb 8/27/2010 United States
Primary
Concomitant
Urticaria 3/1/2010 Male 8/29/2010 Consumer United States
Primary
Concomitant
Pruritus 3/1/2010 57 Male 285 lb 8/29/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 77 Male 201 lb 8/27/2010 United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/9/2010 71 Male 9/9/2010 Other Health Professional United States
Primary
Concomitant
Transplant Failure Other Serious 4/14/2006 44 Male 9/14/2010 Physician Japan
Primary
Secondary
Concomitant
Malaise Other Serious Female 10/2/2010 Consumer United States
Primary
Concomitant
Pulmonary Congestion Other Serious 8/23/2010 81 Female 10/8/2010 Japan
Primary
Secondary
Concomitant
Swelling Other Serious 10/18/2007 40 Female 227 lb 10/15/2010 Other Health Professional United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2008 53 Female 250 lb 10/21/2010 Consumer United States
Primary
Concomitant
Cardiovascular Disorder Hospitalization 1/20/2010 72 Male 202 lb 11/2/2010 Physician Germany
Primary
Concomitant
Urticaria Other Serious 8/23/2010 81 Female 10/27/2010 Japan
Primary
Secondary
Concomitant
Malaise Female 11/11/2010 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious 4/14/2006 44 Male 11/5/2010 Physician Japan
Primary
Secondary
Concomitant
Shock Hospitalization 10/25/2004 57 Female 125 lb 11/10/2010 Lawyer United States
Primary
Concomitant
Dizziness 79 Male 11/23/2010 Physician United States
Primary
Concomitant
Transplant Failure Other Serious 4/14/2006 44 Male 11/16/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 62 Male 11/17/2010 United States
Primary
Concomitant
Pancytopenia Life Threatening 8/18/2010 68 Female 12/10/2010 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/1/2010 68 Female 12/20/2010 Consumer United States
Primary
Concomitant
Haemorrhoidal Haemorrhage Hospitalization 6/26/2010 64 Male 224 lb 7/9/2010 Pharmacist United States
Primary
Secondary
Concomitant
Hiccups 12/8/2010 81 Male 1/5/2011 Consumer
Primary
Concomitant

Drug Data