Actos combined with Amlodipine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Other Serious 69 Female 1/11/2005 Canada
Primary
Concomitant
Dyspnoea Hospitalization 10/1/2003 70 Male 6/30/2005 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Other Serious 2/3/2006 78 Female 3/23/2006 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 2/3/2006 78 Female 4/13/2006 Physician Japan
Primary
Secondary
Concomitant
Hypertension Other Serious 65 Female 12/4/2006 Pharmacist Japan
Primary
Concomitant
Hypertension Other Serious 65 Female 12/19/2006 Pharmacist Japan
Primary
Concomitant
Hypertension Other Serious 65 Female 12/22/2006 Pharmacist Japan
Primary
Concomitant
Renal Failure Acute Other Serious 10/3/2006 Female 247 lb 3/12/2007 Physician France
Primary
Concomitant
Pyrexia Life Threatening 12/31/2006 58 Male 236 lb 3/19/2007 Physician France
Primary
Concomitant
Fibula Fracture Hospitalization 6/1/2006 81 Female 7/6/2007 Physician Belgium
Primary
Concomitant
Vomiting Hospitalization 4/18/2007 73 Female 231 lb 7/23/2007 Germany
Primary
Concomitant
Facial Palsy Other Serious 5/24/2007 53 Male 187 lb 8/3/2007 Physician Netherlands
Primary
Concomitant
Nausea Required Intervention 68 Male 9/7/2007 United Kingdom
Primary
Concomitant
Vascular Graft Required Intervention 69 Female 165 lb 9/20/2007 Physician United States
Primary
Concomitant
Radius Fracture Hospitalization 12/1/2006 59 Female 10/19/2007 Germany
Primary
Concomitant
Rash Erythematous Other Serious 1/1/2007 78 Female 179 lb 11/13/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 9/20/2007 33 Female 11/16/2007 United Kingdom
Primary
Concomitant
Vomiting Other Serious 9/20/2007 33 Female 11/28/2007 United Kingdom
Primary
Concomitant
Angina Pectoris Other Serious 2/4/2008 72 Male 2/28/2008 Other Health Professional Germany
Primary
Concomitant
Rash Erythematous Other Serious 1/1/2007 78 Female 179 lb 3/21/2008 Consumer United States
Primary
Concomitant
Weight Increased Life Threatening 10/1/2007 50 Male 4/8/2008 Physician Germany
Primary
Concomitant
Skin Irritation Other Serious 9/29/2007 34 Female 4/15/2008 United Kingdom
Primary
Concomitant
Weight Increased Life Threatening 10/1/2007 50 Male 4/22/2008 Germany
Primary
Concomitant
Personality Change Other Serious 11/1/2007 Female 5/16/2008 Physician United States
Primary
Concomitant
Lacrimation Increased 4/16/2008 79 Male 201 lb 5/29/2008 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral 1/1/2006 52 Male 161 lb 6/30/2008 Consumer United States
Primary
Secondary
Concomitant
No Adverse Event 2/12/2008 80 Female 174 lb 7/24/2008 Consumer United States
Primary
Concomitant
Blood Glucose Increased 10/15/2007 Male 230 lb 7/25/2008 Consumer United States
Primary
Concomitant
Glossodynia 9/15/2007 Female 182 lb 7/25/2008 Consumer United States
Primary
Secondary
Concomitant
Thoracic Vertebral Fracture Disability 4/29/2008 49 Female 7/23/2008 United Kingdom
Primary
Concomitant
Weight Increased Required Intervention 1/1/2008 61 Female 293 lb 9/30/2008 Other Health Professional United States
Primary
Concomitant
Incorrect Dose Administered 7/1/2008 75 Male 205 lb 9/30/2008 Consumer United States
Primary
Concomitant
Hypoaesthesia Other Serious 1/1/2008 74 Female 110 lb 10/7/2008 United States
Primary
Concomitant
Heart Rate Irregular Hospitalization 7/1/2008 Female 131 lb 9/30/2008 Consumer United States
Primary
Concomitant
Diarrhoea Hospitalization 9/10/2008 Male 10/9/2008 Physician United States
Primary
Concomitant
Myopathy Hospitalization 57 Female 10/13/2008 Physician Japan
Primary
Concomitant
Photophobia 3/1/2008 Female 11/13/2008 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 7/1/2008 Female 131 lb 11/21/2008 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 9/17/2008 64 Male 12/1/2008 Physician United States
Primary
Concomitant
Cough Other Serious 68 Male 12/12/2008 United Kingdom
Primary
Secondary
Concomitant
Somnolence 74 Male 12/10/2008 Consumer United States
Primary
Concomitant
Swelling Face Hospitalization 9/1/2006 77 Male 1/29/2009 Japan
Primary
Concomitant
Ventricular Extrasystoles Other Serious 11/20/2008 Male 143 lb 1/29/2009 Physician Japan
Primary
Concomitant
International Normalised Ratio Decreased Other Serious 12/15/2008 88 Female 1/26/2009 United Kingdom
Primary
Secondary
Concomitant
Completed Suicide Death 50 Male 2/4/2009 Physician United States
Primary
Secondary
Pancreatitis Acute Hospitalization 2/3/2009 Male 2/12/2009 Pharmacist Japan
Primary
Concomitant
Urticaria Hospitalization 1/1/2008 Female 220 lb 2/12/2009 Consumer United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 4/1/2004 81 Male 180 lb 2/23/2009 Consumer United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 2/3/2009 70 Male 2/23/2009 Pharmacist Japan
Primary
Concomitant
Pleural Effusion Hospitalization 1/7/2008 Male 200 lb 2/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/1/2008 Female 220 lb 2/25/2009 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 2/9/2009 75 Female 2/23/2009 Physician Japan
Primary
Concomitant
Nervousness 10/17/2008 50 Male 2/16/2009 United States
Primary
Secondary
Concomitant
Sputum Discoloured Hospitalization 2/25/2009 Male 198 lb 2/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Aortic Dissection Life Threatening 2/4/2009 73 Male 2/25/2009 Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 2/3/2009 70 Male 3/18/2009 Pharmacist Japan
Primary
Concomitant
Sinus Tachycardia Hospitalization 1/7/2009 Male 200 lb 3/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization Female 3/31/2009
Primary
Secondary
Sepsis Other Serious 8/19/2008 4/3/2009 Physician Japan
Primary
Secondary
Concomitant
Laryngeal Cancer Hospitalization 2/1/2008 Male 309 lb 4/3/2009 Physician Germany
Primary
Concomitant
Loss Of Consciousness Hospitalization 3/12/2009 Female 104 lb 4/28/2009 Physician
Primary
Secondary
Concomitant
Mobility Decreased Other Serious 3/10/2009 76 Female 4/24/2009 United Kingdom
Primary
Concomitant
Hypoglycaemia Hospitalization 8/1/2007 Female 4/29/2009
Primary
Concomitant
Chest Pain Hospitalization 4/21/2009 Female 196 lb 5/14/2009 Physician United States
Primary
Secondary
Concomitant
Blood Glucose Increased 1/1/2009 Female 146 lb 5/27/2009 United States
Primary
Concomitant
Bladder Transitional Cell Carcinoma Hospitalization 4/10/2009 66 Male 368 lb 5/28/2009 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 1/7/2009 Male 200 lb 6/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Aortic Dissection Life Threatening 2/4/2009 73 Male 6/5/2009 Japan
Primary
Concomitant
Swollen Tongue Other Serious 3/25/2009 54 Female 260 lb 6/16/2009 Physician United Kingdom
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 5/13/2009 Male 115 lb 6/22/2009 Physician Japan
Primary
Concomitant
Intentional Overdose Required Intervention 4/10/2009 61 Male 6/5/2009 Pharmacist United States
Primary
Secondary
Concomitant
Diabetic Retinopathy Other Serious 12/24/2007 79 Female 6/30/2009 United States
Primary
Concomitant
Dysgeusia 1/20/2009 Male 6/30/2009 United States
Primary
Concomitant
Nausea Other Serious 6/15/2009 7/17/2009 Pharmacist Japan
Primary
Concomitant
Rectal Ulcer Haemorrhage Hospitalization 5/26/2009 Female 205 lb 7/22/2009 Pharmacist Japan
Primary
Concomitant
Renal Impairment Hospitalization 6/1/2009 79 Male 243 lb 7/30/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 6/8/2009 83 8/3/2009 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization Female 176 lb 8/4/2009 Physician United States
Primary
Concomitant
Swelling 2/1/2009 82 Male 8/13/2009 Consumer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 8/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Flushing Female 8/22/2009 United States
Primary
Concomitant
Flushing 4/1/2009 Male 8/22/2009 United States
Primary
Concomitant
Feeling Hot Male 8/23/2009 United States
Primary
Concomitant
Night Sweats 1/1/2008 Male 188 lb 8/23/2009 United States
Primary
Concomitant
Flushing Male 256 lb 8/29/2009 United States
Primary
Concomitant
Pruritus 6/1/2009 Male 250 lb 8/29/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/23/2009 Lawyer United States
Primary
Concomitant
Tibia Fracture Other Serious Female 9/1/2009 United Kingdom
Primary
Concomitant
Infusion Related Reaction Other Serious 9/10/2009 75 Male 214 lb 9/10/2009 Pharmacist United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 1/1/2005 46 Male 245 lb 9/23/2009 United States
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged 7/27/2009 Female 9/23/2009 Physician Japan
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 9/17/2009 United States
Primary
Concomitant
Death Death Male 10/7/2009 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 5/13/2009 Male 115 lb 10/27/2009 Physician Japan
Primary
Secondary
Concomitant
Bladder Transitional Cell Carcinoma Hospitalization 4/10/2009 66 Male 368 lb 11/6/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2009 Male 215 lb 11/11/2009 Physician United States
Primary
Concomitant
Death Death Male 11/24/2009 Consumer United States
Primary
Concomitant
Flushing 8/14/2009 Male 275 lb 11/25/2009 United States
Primary
Concomitant
X-ray Limb Abnormal Other Serious 72 Male 11/16/2009 United States
Primary
Concomitant
Pancreas Lipomatosis Hospitalization 11/1/2009 70 Female 11/23/2009 Japan
Primary
Concomitant
Weight Increased Other Serious 6/1/2009 Female 250 lb 12/9/2009 Other Health Professional United States
Primary
Concomitant
Pancreas Lipomatosis Hospitalization 11/1/2009 70 Female 12/2/2009 Japan
Primary
Concomitant
Hiatus Hernia Hospitalization 10/8/2009 85 Female 150 lb 10/16/2009 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 6/1/2009 Female 250 lb 12/10/2009 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 12/11/2009 United States
Primary
Concomitant
Vision Blurred Female 12/22/2009 Consumer United States
Primary
Concomitant
Cholestatic Liver Injury Hospitalization 4/23/2009 78 Male 1/6/2010 Physician Switzerland
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 1/1/2009 Male 1/7/2010 Physician United States
Primary
Concomitant
Macular Degeneration Other Serious 1/1/2008 74 Female 110 lb 1/19/2010 United States
Primary
Concomitant
Wheezing Hospitalization 12/14/2009 Female 1/19/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 72 Male 201 lb 1/11/2010 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 1/13/2010 United States
Primary
Concomitant
Eye Swelling 5/14/2009 55 Female 1/24/2010 Consumer United States
Primary
Concomitant
Tibia Fracture Other Serious Female 1/18/2010 United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 72 Female 1/7/2010 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/26/2009 73 Male 1/26/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 72 Male 201 lb 1/20/2010 United States
Primary
Concomitant
Weight Increased 9/19/2009 Male 350 lb 1/29/2010 United States
Primary
Concomitant
Left Ventricular Dysfunction Other Serious 1/13/2010 Male 170 lb 2/1/2010 Physician Germany
Primary
Secondary
Concomitant
Arthralgia 1/4/2010 74 Male 220 lb 2/18/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 6/1/2009 Female 266 lb 2/19/2010 Other Health Professional United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 2/1/2009 76 Female 2/9/2010 United Kingdom
Primary
Secondary
Concomitant
Wound Drainage Hospitalization 1/1/2009 Female 2/23/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 6/1/2009 Female 266 lb 2/25/2010 Other Health Professional United States
Primary
Concomitant
Pruritus Hospitalization 2/1/2009 76 Female 2/22/2010 United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Other Serious 1/10/2010 76 Female 66 lb 3/5/2010 Physician Japan
Primary
Concomitant
Retinal Haemorrhage Hospitalization 12/1/2009 61 Male 2/25/2010 France
Primary
Concomitant
Respiratory Failure Other Serious 1/25/2010 56 Male 580 lb 3/2/2010 Physician United States
Primary
Concomitant
Diarrhoea Other Serious 1/10/2010 76 Female 66 lb 3/10/2010 Physician Japan
Primary
Concomitant
Urinary Tract Infection Fungal Hospitalization 11/22/2009 73 Female 3/18/2010 Other Health Professional United States
Primary
Concomitant
White Clot Syndrome Other Serious 5/1/2008 57 Female 3/19/2010 Lawyer United States
Primary
Concomitant
Left Ventricular Failure Hospitalization 2/17/2010 81 Male 3/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 1/25/2010 56 Male 580 lb 3/15/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/25/2010 56 Male 580 lb 3/29/2010 Physician United States
Primary
Concomitant
Constipation Hospitalization 62 Male 212 lb 4/6/2010 Consumer United States
Primary
Concomitant
Umbilical Cord Around Neck Other Serious 9/23/2009 7 lb 4/9/2010 Other Health Professional Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 3/29/2010 65 Female 160 lb 4/8/2010 Consumer United States
Primary
Secondary
Concomitant
Arthralgia 1/1/2010 74 Male 223 lb 4/19/2010 Consumer United States
Primary
Concomitant
Skin Chapped Hospitalization 2/22/2010 65 Female 127 lb 4/19/2010 Physician Japan
Primary
Concomitant
Prostate Cancer Other Serious 1/18/2010 59 Male 176 lb 4/21/2010 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/29/2010 65 Female 160 lb 4/21/2010 Physician United States
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 1/18/2010 59 Male 176 lb 4/28/2010 Physician Germany
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/17/2010 84 Male 4/29/2010 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 6/1/2009 79 Male 243 lb 5/4/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 67 Male 5/4/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 5/5/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 5/19/2010 United States
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 2/23/2008 60 Female 5/13/2010 United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 5/6/2010 84 Male 5/20/2010 Physician Japan
Primary
Concomitant

Drug Data