Actonel combined with Coumadin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wrist Fracture Other Serious 4/11/1999 75 Female 150 lb 1/3/2006 Physician United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 12/13/2005 81 Male 193 lb 1/5/2006 Physician United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 12/13/2005 81 Male 193 lb 1/23/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 3/26/2004 Male 110 lb 1/31/2006 Physician United States
Primary
Concomitant
Neoplasm Malignant Death Female 2/3/2006 Physician United States
Primary
Concomitant
Dyspnoea Life Threatening 1/7/2006 Female 126 lb 2/3/2006 Pharmacist United States
Primary
Concomitant
Haematuria Hospitalization 10/31/2005 Female 113 lb 1/10/2006 Pharmacist United States
Primary
Concomitant
Unresponsive To Pain Stimuli Hospitalization 1/11/2006 Female 2/23/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 3/26/2004 Male 110 lb 3/17/2006 Physician United States
Primary
Concomitant
Pain In Jaw Other Serious 1/19/2005 76 Male 178 lb 3/20/2006 Physician United States
Primary
Concomitant
Sudden Death Other Serious 10/20/2003 76 Female 4/4/2006 Physician United States
Primary
Concomitant
Venous Thrombosis Other Serious 1/1/2000 71 Female 11/4/2005 Physician United States
Primary
Secondary
Concomitant
Coronary Artery Occlusion Other Serious 3/27/2006 78 Female 140 lb 4/12/2006 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2005 78 Female 59 lb 5/19/2006 United States
Primary
Concomitant
Nausea Hospitalization 9/26/2004 65 Female 370 lb 5/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 12/27/2005 63 Female 127 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2005 78 Female 59 lb 6/21/2006 Physician United States
Primary
Concomitant
Headache 1/20/2006 94 Female 5/5/2006 Consumer United States
Primary
Concomitant
Diarrhoea 2/22/2006 82 Male 5/5/2006 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 12/27/2005 75 Female 160 lb 6/20/2006 Canada
Primary
Secondary
Concomitant
Somnolence Other Serious 3/1/2006 88 Female 136 lb 6/30/2006 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2005 60 Female 7/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Malaise Hospitalization 6/1/2005 63 Female 7/20/2006 United States
Primary
Concomitant
Pruritus 1/1/2005 70 Female 134 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Fluctuation Life Threatening 7/14/2005 67 Female 143 lb 8/1/2006 Physician United States
Primary
Concomitant
Interacting
Transient Ischaemic Attack Hospitalization 9/1/2005 70 Male 165 lb 8/1/2006 Consumer United States
Primary
Concomitant
Weight Increased 10/1/2005 67 Female 174 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Abnormal 1/1/2005 76 Female 128 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased 8/1/2006 Consumer United States
Primary
Concomitant
Bone Density Decreased 48 Female 117 lb 8/1/2006 Consumer United States
Primary
Concomitant
Haematochezia 4/11/2006 85 Female 121 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased 3/1/2006 81 Female 123 lb 8/1/2006 Consumer United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 77 Female 8/11/2006 United States
Primary
Secondary
Concomitant
Vasoconstriction Other Serious 8/1/2006 Female 169 lb 9/1/2006 Consumer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 8/15/2001 Male 9/6/2006 Physician United States
Primary
Concomitant
Swelling 6/19/2006 76 Female 200 lb 7/19/2006 Consumer United States
Primary
Concomitant
Vasoconstriction Other Serious 8/1/2006 Female 169 lb 9/27/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/1/2006 Female 194 lb 10/25/2006 Other Health Professional United States
Primary
Concomitant
Urinary Retention Hospitalization 11/30/2005 86 Male 220 lb 11/14/2006 United States
Primary
Concomitant
Death Death 12/7/2006 70 Female 12/15/2006 Consumer Canada
Primary
Concomitant
Prothrombin Time Shortened Hospitalization 9/28/2006 43 Male 205 lb 12/6/2006 Other Health Professional France
Primary
Concomitant
Death Death 12/6/2006 70 Female 12/19/2006 Physician Canada
Primary
Concomitant
Malaise 10/1/2006 Male 12/22/2006 Consumer United States
Primary
Concomitant
Silent Myocardial Infarction Hospitalization 80 Female 1/22/2007 Consumer United States
Primary
Concomitant
Pain In Extremity Hospitalization 8/28/2006 76 Female 158 lb 1/30/2007 Physician United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 12/1/2005 Male 199 lb 1/27/2007 United States
Primary
Secondary
Concomitant
Frequent Bowel Movements Other Serious 73 Female 137 lb 8/19/2005 Physician United States
Primary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 2/16/2007 United States
Primary
Secondary
Concomitant
Death Death 9/26/2006 Female 2/20/2007 Other Health Professional United States
Primary
Concomitant
Skin Cancer Other Serious 4/1/2006 76 Male 198 lb 2/27/2007 Consumer United States
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Death 76 Male 3/9/2007 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2004 71 Female 3/14/2007 Consumer United States
Primary
Concomitant
Hypersensitivity Hospitalization 3/2/2007 69 Female 150 lb 3/19/2007 United States
Primary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 4/3/2007 Physician United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Hospitalization 3/2/2007 69 Female 150 lb 4/20/2007 Physician United States
Primary
Concomitant
Vein Disorder Other Serious 1/1/1998 60 Female 5/4/2007 Physician United States
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization Female 150 lb 4/20/2007 Physician United States
Primary
Concomitant
Vertebral Artery Stenosis Other Serious 11/1/2004 56 Female 5/14/2007 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1999 Female 5/17/2007 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1999 Female 5/25/2007 Physician United States
Primary
Concomitant
Vitreous Floaters Hospitalization 1/1/2004 69 Female 171 lb 5/25/2007 Consumer United States
Primary
Secondary
Concomitant
Haemorrhage Other Serious Female 128 lb 6/4/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 9/5/2006 82 Female 5/25/2007 United States
Primary
Concomitant
Thrombosis Other Serious 11/22/2005 47 Female 130 lb 6/29/2007 Other Health Professional United States
Primary
Concomitant
Breast Cancer Hospitalization 11/25/2006 78 Female 6/28/2007 Consumer United States
Primary
Concomitant
Presyncope Hospitalization 5/1/2007 86 Male 7/10/2007 United States
Primary
Concomitant
Pruritus 6/2/2007 78 Female 8/3/2007 Consumer United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 11/1/2004 56 Female 8/16/2007 Physician United States
Primary
Concomitant
Osteopenia Hospitalization 2/21/2007 53 Female 8/23/2007 Consumer United States
Primary
Concomitant
Vocal Cord Paralysis Other Serious 8/6/2007 Female 194 lb 9/13/2007 Other Health Professional United States
Primary
Concomitant
Haemorrhage Other Serious Female 128 lb 9/26/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 7/29/2007 62 Female 192 lb 10/9/2007 Physician Canada
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 11/1/2004 56 Female 10/8/2007 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 6/1/2007 64 Female 165 lb 10/10/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased Other Serious 7/4/2007 87 Female 10/17/2007 Other Health Professional France
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/12/2005 80 Male 179 lb 10/15/2007 Physician United States
Primary
Secondary
Concomitant
Headache 79 Female 10/24/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 5/7/2007 60 Female 10/26/2007 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 10/22/2007 Female 11/12/2007 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 1/6/2007 Female 164 lb 11/26/2007 Consumer United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization Female 12/11/2007 Consumer United States
Primary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 12/19/2007 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2007 Female 100 lb 12/21/2007 Consumer United States
Primary
Concomitant
Pain Other Serious 1/1/2007 Female 100 lb 12/20/2007 Consumer United States
Primary
Concomitant
Pain In Extremity Hospitalization 6/1/2007 64 Female 165 lb 1/3/2008 Consumer United States
Primary
Concomitant
Occult Blood Positive Hospitalization 1/1/2008 74 Female 148 lb 1/2/2008 Pharmacist United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 10/22/2007 Female 1/9/2008 Consumer United States
Primary
Concomitant
Pancytopenia Other Serious 2/4/2007 67 Female 178 lb 1/9/2008 Pharmacist United States
Primary
Concomitant
Dyspnoea Hospitalization 10/22/2007 Female 1/16/2008 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 7/10/2007 82 Female 1/18/2008 Consumer France
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 10/26/2007 Female 152 lb 1/25/2008 Consumer United States
Primary
Concomitant
Malaise Hospitalization 6/1/2005 67 Female 2/19/2008 United States
Primary
Concomitant
Wrong Drug Administered Hospitalization 11/20/2007 72 Female 138 lb 2/11/2008 Physician United States
Primary
Secondary
Concomitant
Hypocoagulable State Hospitalization Female 192 lb 3/12/2008 Pharmacist United States
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 70 Female 3/11/2008 Physician United States
Primary
Concomitant
Medication Error Other Serious 11/20/2007 Female 116 lb 3/14/2008 Physician United States
Primary
Secondary
Concomitant
Hypocoagulable State Hospitalization Female 192 lb 3/18/2008 Pharmacist United States
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 86 Female 3/21/2008 Pharmacist United States
Primary
Concomitant
Hypocoagulable State Hospitalization Female 192 lb 3/25/2008 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 10/22/2007 Female 161 lb 3/26/2008 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 11/1/2007 70 Female 3/24/2008 Physician United States
Primary
Concomitant
Hypocoagulable State Hospitalization Female 192 lb 3/28/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2000 Female 110 lb 3/31/2008 Other Health Professional United States
Primary
Concomitant
Malaise Hospitalization 6/1/2005 63 Female 4/4/2008 United States
Primary
Concomitant
Herpes Zoster Female 4/11/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 12/4/2007 70 Female 135 lb 4/16/2008 Physician United States
Primary
Concomitant
Cerebrovascular Accident Other Serious Female 4/14/2008 Consumer United States
Primary
Concomitant
Pruritus 3/9/2007 Female 4/28/2008 Consumer United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 68 Female 5/1/2008 United States
Primary
Concomitant
Gastrooesophageal Reflux Disease 10/1/2007 88 Male 178 lb 6/6/2008 Consumer United States
Primary
Concomitant
Palatal Disorder Other Serious 6/3/2002 53 Female 4/24/2008 Physician United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Other Serious 5/2/2008 88 Female 6/23/2008 Other Health Professional France
Primary
Concomitant
Atrial Fibrillation Life Threatening 6/1/2007 57 Female 140 lb 6/20/2008 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Other Serious Female 7/8/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2008 Female 158 lb 7/17/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1998 70 Female 106 lb 7/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hair Growth Abnormal 1/1/2008 74 Female 7/21/2008 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased Hospitalization 1/27/2007 Male 161 lb 7/29/2008 Consumer United States
Primary
Concomitant
Herpes Zoster Female 7/29/2008 Consumer United States
Primary
Secondary
Burning Sensation 1/1/2006 81 Female 146 lb 7/29/2008 Consumer United States
Primary
Concomitant
Therapy Regimen Changed 62 Female 170 lb 7/29/2008 Consumer United States
Primary
Secondary
Concomitant
Hypoaesthesia 2/1/2008 78 Male 150 lb 7/29/2008 Consumer United States
Primary
Concomitant
International Normalised Ratio Fluctuation 81 Female 172 lb 7/29/2008 Consumer United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 68 Female 140 lb 7/29/2008 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Death 5/24/2008 61 Female 112 lb 8/15/2008 Consumer United States
Primary
Concomitant
No Adverse Event Female 8/13/2008 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Death 5/24/2008 61 Female 112 lb 8/21/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 5/29/2008 81 Female 107 lb 8/22/2008 Other Health Professional United States
Primary
Concomitant
Back Pain 8/26/2007 92 Female 9/4/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1998 70 Female 106 lb 9/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 3/24/2003 9/24/2008 Physician United States
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 1/1/1998 63 Male 194 lb 9/27/2008 Lawyer United States
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 1/1/1998 63 Male 194 lb 10/1/2008 Lawyer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization Female 177 lb 10/7/2008 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization Female 177 lb 10/15/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 5/29/2008 81 Female 236 lb 10/10/2008 United States
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/2000 52 Female 10/24/2008 United States
Primary
Concomitant
Urinary Incontinence 1/1/2008 91 Male 10/24/2008 Consumer
Primary
Concomitant
Dementia Other Serious 1/1/2006 Female 126 lb 11/4/2008 Physician United States
Primary
Concomitant
Subcutaneous Nodule Other Serious 1/1/1998 63 Male 194 lb 11/11/2008 Lawyer United States
Primary
Secondary
Concomitant
Hypercalcaemia Other Serious 10/16/2008 Female 11/13/2008 Consumer United States
Primary
Concomitant
Hypercalcaemia Other Serious 10/16/2008 Female 11/17/2008 Consumer United States
Primary
Concomitant
Atrial Fibrillation Other Serious 10/1/2008 66 Female 12/1/2008 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 5/29/2008 81 Female 107 lb 11/20/2008 United States
Primary
Concomitant
Weight Increased Hospitalization 5/28/2008 81 Female 107 lb 11/26/2008 United States
Primary
Concomitant
Muscle Spasms 81 Female 154 lb 12/16/2008 Consumer United States
Primary
Concomitant
Urinary Incontinence 1/1/2008 91 Male 12/17/2008 Consumer
Primary
Concomitant
Atrial Fibrillation Other Serious 10/1/2008 Female 221 lb 12/31/2008 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 4/15/2008 81 Female 107 lb 12/31/2008 United States
Primary
Concomitant
Subcutaneous Nodule Other Serious 1/1/1998 63 Male 194 lb 1/7/2009 Lawyer United States
Primary
Secondary
Concomitant

Drug Data