Activase combined with Aspirin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urinary Retention Hospitalization 3/9/2005 65 Male 137 lb 1/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Electromechanical Dissociation Death 5/3/2004 71 Female 154 lb 1/30/2006 Other Health Professional Romania
Primary
Secondary
Concomitant
Haemorrhagic Infarction Death 1/26/2005 86 Male 160 lb 2/3/2006 Pharmacist United States
Primary
Concomitant
Reperfusion Injury Other Serious 43 Male 2/7/2006 Switzerland
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/20/2006 68 Male 3/24/2006 Physician France
Primary
Concomitant
Intracardiac Thrombus Other Serious 7/18/2003 48 Male 220 lb 4/3/2006 Other Health Professional Russian Federation
Primary
Secondary
Intracardiac Thrombus Other Serious 7/1/2003 45 Male 165 lb 4/3/2006 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 3/9/2005 65 Male 137 lb 4/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Varicose Vein Operation Hospitalization 1/1/2000 53 Male 351 lb 5/5/2006 Lawyer United States
Primary
Concomitant
Varicose Vein Operation Hospitalization 1/1/2000 53 Male 351 lb 5/9/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 3/26/2006 86 Male 119 lb 9/27/2006 Physician United States
Primary
Secondary
Concomitant
Malaise Hospitalization 5/17/2006 72 Male 9/27/2006 Other Health Professional Japan
Primary
Concomitant
Haemopneumothorax Hospitalization 10/12/2006 Male 269 lb 10/30/2006 United States
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 10/1/2006 86 Female 12/1/2006 Physician United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 71 Female 1/12/2007 Other Health Professional Germany
Primary
Concomitant
Drug Ineffective Death 1/10/2007 65 Male 1/22/2007 Other Health Professional India
Primary
Concomitant
Brain Herniation Other Serious 4/5/2007 65 Male 4/23/2007 Physician Japan
Primary
Concomitant
Brain Herniation Other Serious 4/5/2007 65 Male 4/30/2007 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 7/15/2006 70 Male 5/21/2007 Consumer Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Required Intervention 5/6/2007 Female 270 lb 5/18/2007 Pharmacist United States
Primary
Concomitant
Renal Disorder Hospitalization 3/20/2006 60 Male 6/19/2007 Consumer Japan
Primary
Concomitant
Cerebral Haemorrhage Disability 11/5/2006 80 Male 6/26/2007 Physician Japan
Primary
Concomitant
Haemorrhage Intracranial Death Female 146 lb 6/26/2007 Consumer United States
Primary
Concomitant
Cerebral Haemorrhage Death 72 Female 7/11/2007 Physician Germany
Primary
Concomitant
Liver Disorder Other Serious 3/22/2007 45 Male 7/17/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Other Serious 11/5/2006 80 Male 7/26/2007 Physician Japan
Primary
Concomitant
Pericardial Haemorrhage Death 57 Male 8/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pericardial Haemorrhage Death 57 Male 8/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Intra-abdominal Haemorrhage Hospitalization 79 Male 9/25/2007 Physician Japan
Primary
Concomitant
Poor Peripheral Circulation Hospitalization 12/14/2006 87 Female 9/28/2007 Physician United States
Primary
Concomitant
Epilepsy Other Serious 7/8/2007 69 Male 10/19/2007 Physician Japan
Primary
Concomitant
Coma Death 3/4/2003 Female 11/1/2007 Physician Germany
Primary
Concomitant
White Blood Cell Analysis Increased Other Serious 1/1/2000 71 Female 11/22/2007 United States
Primary
Secondary
Concomitant
Epilepsy Other Serious 7/8/2007 69 Male 12/11/2007 Physician Japan
Primary
Concomitant
Atrial Fibrillation Hospitalization 8/14/2007 63 Female 4/1/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Shock Haemorrhagic Other Serious 8/30/2007 87 Female 4/7/2008 Physician Japan
Primary
Concomitant
Atrial Fibrillation Hospitalization 8/14/2007 63 Female 5/16/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 75 Female 5/29/2008 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 3/22/2007 45 Male 6/19/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Death 85 Male 7/23/2008 Physician Germany
Primary
Concomitant
Cerebral Haemorrhage Other Serious 7/31/2008
Primary
Secondary
Splenic Abscess Hospitalization 3/26/2006 87 Male 119 lb 9/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Other Serious 9/19/2008
Primary
Secondary
Cerebral Haemorrhage Other Serious 10/21/2008
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious Female 12/4/2008
Primary
Secondary
Splenic Abscess Hospitalization 3/26/2006 87 Male 119 lb 12/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious Female 12/11/2008
Primary
Secondary
Intraocular Pressure Increased Other Serious 81 Female 12/17/2008 Physician Germany
Primary
Secondary
Concomitant
Intraocular Pressure Increased Other Serious 77 12/17/2008 Physician Germany
Primary
Secondary
Concomitant
Intraocular Pressure Increased Other Serious 81 Female 12/17/2008 Physician Germany
Primary
Secondary
Concomitant
Intraocular Pressure Increased Other Serious 77 12/17/2008 Physician Germany
Primary
Secondary
Concomitant
Intraocular Pressure Increased Other Serious 81 Female 12/18/2008 Physician Germany
Primary
Secondary
Concomitant
Intraocular Pressure Increased Other Serious 81 Female 12/18/2008 Physician Germany
Primary
Secondary
Concomitant
Intraocular Pressure Increased Other Serious 77 Female 12/24/2008 Physician Germany
Primary
Secondary
Concomitant
Intraocular Pressure Increased Other Serious 77 Female 12/24/2008 Physician Germany
Primary
Secondary
Concomitant
Gastric Haemorrhage Other Serious Male 1/9/2009 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Required Intervention 1/1/2008 3 Female 1/16/2009 Physician United States
Primary
Concomitant
Vascular Occlusion Other Serious Male 1/23/2009 Physician United States
Primary
Secondary
Myocardial Rupture Death 8/12/2008 63 Male 2/6/2009 Other Health Professional Japan
Primary
Concomitant
Pneumonia Cryptococcal Hospitalization 11/22/2008 Male 220 lb 2/9/2009 United States
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 1/1/2009 Female 166 lb 4/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Artery Dissection Other Serious 9/3/2008 Female 4/14/2009 Other Health Professional Japan
Primary
Concomitant
Peripheral Embolism Other Serious 4/28/2009 Physician Germany
Primary
Secondary
Gastric Haemorrhage Other Serious Male 4/28/2009 Physician Germany
Primary
Secondary
Peripheral Embolism Other Serious 4/28/2009 Physician Germany
Primary
Secondary
Renal Failure Other Serious 4/28/2009 Physician Germany
Primary
Secondary
Myocardial Infarction Other Serious 3/25/2009 72 Male 201 lb 5/6/2009 Physician Switzerland
Primary
Secondary
Concomitant
Myocardial Infarction Death 3/25/2009 72 Male 201 lb 5/6/2009 Physician Switzerland
Primary
Secondary
Concomitant
Interacting
Neurological Symptom Death 5/6/2009 72 Male 91 lb 5/6/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 3/25/2009 73 Male 201 lb 5/7/2009 Physician Switzerland
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 5/13/2009 Germany
Primary
Secondary
Nervous System Disorder Death 3/25/2009 72 Male 5/11/2009 Other Health Professional Switzerland
Primary
Secondary
Renal Failure Other Serious 5/29/2009 Physician Germany
Primary
Secondary
Ventricular Tachycardia Other Serious 5/29/2009 Physician Germany
Primary
Secondary
Ventricular Tachycardia Other Serious 5/29/2009 Physician Germany
Primary
Secondary
Haemorrhagic Cerebral Infarction Hospitalization 1/8/2009 66 Female 141 lb 5/11/2009 Pharmacist United States
Primary
Concomitant
Vomiting Life Threatening 5/4/2009 75 Female 139 lb 6/11/2009 Pharmacist United States
Primary
Concomitant
Death Other Serious 7/17/2009
Primary
Secondary
Concomitant
Death Other Serious 7/21/2009 Germany
Primary
Secondary
Concomitant
Death Death 7/28/2009 Physician Germany
Primary
Secondary
Death Death 7/28/2009 Physician Germany
Primary
Secondary
Renal Failure Death 7/28/2009 Physician Germany
Primary
Secondary
Tracheal Disorder Other Serious 59 Male 9/3/2009 Physician Singapore
Primary
Secondary
Haemorrhagic Infarction Other Serious 82 Female 9/10/2009 Norway
Primary
Secondary
Angioedema Other Serious 74 Male 9/19/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/3/2009 65 Female 154 lb 12/22/2009 Consumer United States
Primary
Concomitant
Post Procedural Haematoma Other Serious 11/17/2009 Male 1/19/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 2/22/2008 46 Male 280 lb 3/8/2010 Lawyer United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 9/1/2004 Female 3/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 9/1/2004 58 Female 4/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Retinal Haemorrhage Other Serious 74 Male 5/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 2/22/2008 46 Male 280 lb 5/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Peripheral Embolism Other Serious 11/15/2007 62 Male 201 lb 6/16/2010 Lawyer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 9/1/2004 58 Female 7/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 6/8/2004 58 Female 7/21/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/28/2008 74 Male 190 lb 8/6/2010 Other Health Professional United States
Primary
Concomitant
Swollen Tongue Life Threatening 8/1/2010 75 Female 176 lb 8/3/2010 Pharmacist United States
Primary
Concomitant
Vascular Graft Thrombosis Other Serious 11/15/2007 62 Male 201 lb 8/11/2010 Other Health Professional United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/2008 77 Male 8/18/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 61 Male 187 lb 8/19/2010 Other Health Professional United States
Primary
Concomitant
Aortic Aneurysm Rupture Death 8/11/2010 83 Male 8/27/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Aortic Aneurysm Rupture Other Serious 8/11/2010 83 Male 8/30/2010 Other Health Professional Japan
Primary
Secondary
Sepsis Other Serious 1/1/2008 42 Female 9/2/2010 Lawyer United States
Primary
Concomitant
Aortic Aneurysm Rupture Death 8/11/2010 83 Male 9/2/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Aortic Aneurysm Rupture Death 8/11/2010 83 Male 9/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Aortic Aneurysm Rupture Death 8/11/2010 83 Male 9/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 6/8/2004 58 Female 9/22/2010 United States
Primary
Secondary
Concomitant
Thrombosis In Device Other Serious 1/1/2010 74 Female 9/29/2010 Physician United States
Primary
Concomitant
Thrombosis In Device Other Serious 1/1/2010 74 Female 9/29/2010 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2008 77 Male 146 lb 10/13/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 2/22/2008 46 Male 280 lb 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 9/1/2007 57 Male 231 lb 10/28/2010 Lawyer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 2/1/2008 12 Female 66 lb 10/28/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 63 Male 205 lb 11/8/2010 Lawyer United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/13/2009 49 Female 128 lb 11/11/2010 Consumer United States
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 10/10/2010 76 Female 11/11/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 61 Male 187 lb 11/18/2010 Other Health Professional United States
Primary
Concomitant
Liver Disorder Hospitalization 10/10/2010 76 Female 12/2/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Death 78 Male 11/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhagic Stroke Death 12/7/2010 88 Female 132 lb 12/23/2010 Other Health Professional United States
Primary
Concomitant
Abdominal Pain Death 1/25/2008 38 Male 260 lb 1/12/2011 Lawyer United States
Primary
Secondary
Concomitant
Asthenia Other Serious 1/1/2008 74 Male 190 lb 2/3/2011 Lawyer United States
Primary
Concomitant
Ischaemic Cardiomyopathy Hospitalization 82 Male 1/27/2011 United States
Primary
Concomitant
Cerebral Haemorrhage Death 8/2/2010 77 Female 165 lb 11/16/2010 Physician United States
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 6/8/2004 58 Female 3/2/2011 Lawyer United States
Primary
Secondary
Concomitant
Haemorrhagic Transformation Stroke Hospitalization 41 Male 3/4/2011 Physician Saudi Arabia
Primary
Secondary
General Physical Health Deterioration Death 41 Male 3/10/2011 Other Health Professional Saudi Arabia
Primary
Secondary
Erythema Other Serious 11/15/2007 62 Male 201 lb 3/30/2011 Other Health Professional United States
Primary
Concomitant
Paralysis Other Serious 2/20/2011 64 Female 4/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Death 2/19/2007 89 Male 5/6/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Death 2/19/2007 89 Male 5/6/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Haemorrhage Intracranial Death 4/13/2011 85 Female 5/12/2011 Pharmacist United States
Primary
Secondary
Lymphadenopathy Mediastinal Other Serious 6/8/2004 58 Female 6/13/2011 Lawyer United States
Primary
Secondary
Concomitant
Haemorrhagic Stroke Hospitalization 4/23/2011 55 Female 6/20/2011 Consumer United States
Primary
Secondary
Concomitant
Thoracic Vertebral Fracture Other Serious 6/8/2004 58 Female 6/27/2011 United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 5/11/2011 77 Male 9/2/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Cardiac Failure Death 11/26/2010 84 Male 9/8/2011 Physician Japan
Primary
Concomitant
Anaphylactic Reaction Death 8/7/2011 71 Female 262 lb 9/23/2011 Pharmacist United States
Primary
Concomitant
Neurological Symptom Death 47 Male 10/14/2011 United States
Primary
Concomitant
Hypoaesthesia Other Serious 48 Female 10/14/2011 United States
Primary
Secondary
Angioedema Other Serious 8/25/2011 77 Female 10/15/2011 Other Health Professional United States
Primary
Concomitant
Angioedema Death 8/7/2011 71 Female 262 lb 10/18/2011 Pharmacist United States
Primary
Concomitant
Sinus Bradycardia Hospitalization 6/8/2004 58 Female 10/28/2011 Physician United States
Primary
Secondary
Concomitant
Cough Death 8/22/2011 50 Male 11/1/2011 Physician Ukraine
Primary
Concomitant
Angioedema Life Threatening 1/10/2010 80 Male 11/2/2011 Physician Netherlands
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 56 Male 11/2/2011 Other Health Professional United States
Primary
Concomitant
Left Ventricular Hypertrophy Other Serious 2/16/2011 62 Male 186 lb 11/21/2011 Lawyer United States
Primary
Concomitant
Tongue Oedema Disability 3/31/2011 55 Female 12/2/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 11/26/2010 84 Male 12/2/2011 Physician Japan
Primary
Concomitant
Ecchymosis Hospitalization Female 219 lb 12/12/2011 Lawyer United States
Primary
Concomitant

Drug Data