Actemra combined with Rheumatrex

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
C-reactive Protein Increased Hospitalization 9/20/2008 Male 98 lb 1/14/2010 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 9/1/2009 Male 117 lb 1/15/2010 Physician Japan
Primary
Concomitant
Gastric Cancer Other Serious 6/24/2009 Female 126 lb 1/21/2010 Physician Japan
Primary
Secondary
Concomitant
Gastric Cancer Other Serious 6/24/2009 Female 126 lb 1/29/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization Female 132 lb 3/16/2010 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 9/1/2009 Male 117 lb 3/16/2010 Physician Japan
Primary
Concomitant
Shock Hospitalization 2/24/2010 Female 97 lb 3/19/2010 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 1/4/2010 Female 104 lb 3/19/2010 Physician Japan
Primary
Secondary
Concomitant
Shock Hospitalization 2/24/2010 74 Female 97 lb 4/9/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 5/15/2009 58 Female 4/15/2010 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 4/9/2010 70 Female 4/19/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Life Threatening 2/16/2010 72 Male 118 lb 4/23/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 5/15/2009 58 Female 4/23/2010 Physician Japan
Primary
Concomitant
Pneumonia Death 2/28/2010 81 Male 4/27/2010 Physician Japan
Primary
Secondary
Interstitial Lung Disease Hospitalization 2/28/2010 78 Female 128 lb 4/28/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 4/17/2010 73 Male 128 lb 5/4/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 5/15/2009 58 Female 106 lb 5/6/2010 Physician Japan
Primary
Concomitant
Myocardial Infarction Life Threatening 2/16/2010 72 Male 118 lb 5/20/2010 Physician Japan
Primary
Concomitant
Ovarian Cancer Recurrent Other Serious 5/17/2010 65 Female 112 lb 5/26/2010 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Other Serious 4/22/2010 62 Male 121 lb 6/25/2010 Other Health Professional Japan
Primary
Concomitant
Pulmonary Tuberculosis Life Threatening 5/1/2008 69 Female 90 lb 6/29/2010 Other Health Professional Japan
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 4/28/2010 43 Female 110 lb 7/2/2010 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Oticus Hospitalization 4/13/2010 67 Female 93 lb 7/15/2010 Physician Japan
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 4/28/2010 43 Female 110 lb 7/16/2010 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 4/29/2010 56 Male 7/19/2010 Physician Japan
Primary
Concomitant
Urticaria Hospitalization 5/10/2010 29 Female 130 lb 7/20/2010 Physician Japan
Primary
Concomitant
Pruritus Other Serious 1/16/2009 63 Female 130 lb 7/22/2010 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Life Threatening 5/1/2008 69 Female 90 lb 7/27/2010 Other Health Professional Japan
Primary
Concomitant
Peritonitis Other Serious 5/21/2010 61 Female 8/5/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 6/16/2010 67 Female 101 lb 8/10/2010 Physician Japan
Primary
Secondary
Rib Fracture Other Serious 9/18/2008 67 Female 110 lb 8/12/2010 Physician Japan
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Other Serious 7/14/2010 21 Female 101 lb 8/13/2010 Physician Japan
Primary
Concomitant
Cerebral Infarction Other Serious Female 8/16/2010 Physician Japan
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 4/28/2010 43 Female 110 lb 8/20/2010 Physician Japan
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Hospitalization 7/14/2010 21 Female 101 lb 8/26/2010 Physician Japan
Primary
Concomitant
Cerebral Infarction Other Serious Female 8/30/2010 Physician Japan
Primary
Concomitant
Rib Fracture Other Serious 9/18/2008 67 Female 110 lb 9/1/2010 Physician Japan
Primary
Secondary
Concomitant
Fasciitis Hospitalization 6/25/2010 10 Male 79 lb 9/4/2010 Physician Japan
Primary
Concomitant
Oedema Peripheral Hospitalization 4/29/2010 56 Male 9/15/2010 Physician Japan
Primary
Concomitant
Large Intestine Perforation Hospitalization 9/3/2010 60 Female 77 lb 9/20/2010 Physician Japan
Primary
Secondary
Concomitant
Pruritus Other Serious 1/16/2009 63 Female 130 lb 9/21/2010 Physician Japan
Primary
Secondary
Concomitant
Fasciitis Hospitalization 6/25/2010 10 Male 79 lb 10/1/2010 Physician Japan
Primary
Concomitant
Skin Cancer Life Threatening 9/20/2008 77 Male 98 lb 10/6/2010 Physician Japan
Primary
Secondary
Concomitant
Ventricular Arrhythmia Other Serious 1/11/2010 37 Female 64 lb 10/7/2010 Physician Japan
Primary
Concomitant
Sepsis Other Serious 6/5/2010 67 Female 93 lb 10/7/2010 Physician Japan
Primary
Secondary
Concomitant
Sapho Syndrome Hospitalization 4/1/2010 57 Female 117 lb 10/11/2010 Physician Japan
Primary
Concomitant
Neoplasm Malignant Life Threatening 9/22/2008 53 Female 10/14/2010 Physician Japan
Primary
Concomitant
Skin Cancer Other Serious Female 157 lb 10/22/2010 Physician Japan
Primary
Concomitant
Large Intestine Perforation Other Serious 9/6/2010 60 Female 75 lb 10/27/2010 Physician Japan
Primary
Secondary
Concomitant
Large Intestine Perforation Other Serious 9/6/2010 60 Female 75 lb 10/28/2010 Physician Japan
Primary
Secondary
Concomitant
Skin Cancer Other Serious Female 157 lb 11/4/2010 Physician Japan
Primary
Concomitant
Pneumonitis Other Serious 8/16/2010 66 Male 126 lb 11/5/2010 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 6/30/2008 77 Female 11/24/2010 Physician Japan
Primary
Concomitant
Sapho Syndrome Hospitalization 5/12/2010 57 Female 117 lb 12/3/2010 Physician Japan
Primary
Concomitant
Portal Vein Thrombosis Hospitalization 11/10/2010 72 Female 110 lb 12/8/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 2/28/2010 78 Female 128 lb 12/14/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 2/28/2010 78 Female 128 lb 12/20/2010 Physician Japan
Primary
Secondary
Concomitant
Skin Cancer Life Threatening 9/20/2008 77 Male 98 lb 12/23/2010 Physician Japan
Primary
Secondary
Concomitant
Portal Vein Thrombosis Other Serious 11/10/2010 72 Female 110 lb 12/27/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 10/25/2010 67 Female 12/28/2010 Physician Japan
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Life Threatening 10/25/2010 49 Female 90 lb 12/29/2010 Physician Japan
Primary
Secondary
Concomitant
Osteoarthritis Hospitalization 6/1/2010 67 Female 12/30/2010 Physician Japan
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Hospitalization 12/13/2010 50 Female 12/30/2010 Physician Japan
Primary
Concomitant
Arthritis Other Serious 12/27/2010 53 Male 112 lb 1/11/2011 Other Health Professional Japan
Primary
Concomitant
Periarthritis Hospitalization 12/28/2010 53 Male 110 lb 1/21/2011 Physician Japan
Primary
Concomitant
Subarachnoid Haemorrhage Hospitalization 12/30/2010 56 Female 115 lb 1/31/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 1/16/2009 63 Female 130 lb 2/1/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 6/1/2010 67 Female 2/1/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Diverticulitis Other Serious 2/15/2010 47 Male 165 lb 2/9/2011 Physician Japan
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Hospitalization 3/26/2009 53 Male 2/10/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Diverticulitis Other Serious 2/15/2010 47 Male 165 lb 2/11/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hyperlipidaemia Other Serious 5/7/2010 55 Female 115 lb 2/14/2011 Physician Japan
Primary
Concomitant
Anal Ulcer Haemorrhage Hospitalization 6/30/2008 77 Female 2/23/2011 Other Health Professional Japan
Primary
Concomitant
Large Intestine Perforation Other Serious 9/6/2010 60 Female 75 lb 3/3/2011 Physician Japan
Primary
Secondary
Concomitant
Pyrexia 1/13/2010 38 Female 126 lb 3/7/2011 Other Health Professional Japan
Primary
Concomitant
Rheumatoid Arthritis Other Serious 4/22/2010 62 Male 121 lb 3/10/2011 Other Health Professional Japan
Primary
Concomitant
Anaemia Hospitalization 6/30/2008 77 Female 3/23/2011 Other Health Professional Japan
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 1/11/2011 69 Female 95 lb 3/29/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious Female 4/14/2011 Other Health Professional Japan
Primary
Concomitant
Pulmonary Oedema Hospitalization 12/4/2009 65 Male 150 lb 4/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 6/26/2010 77 Female 101 lb 4/27/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Cellulitis Other Serious 4/22/2010 62 Male 121 lb 4/29/2011 Physician Japan
Primary
Concomitant
Endophthalmitis Disability 12/16/2010 72 Female 104 lb 4/29/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Disability 3/5/2011 59 Female 5/4/2011 Physician Japan
Primary
Concomitant
Cellulitis Hospitalization 6/4/2008 55 Female 117 lb 5/13/2011 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 2/16/2011 63 Female 99 lb 5/20/2011 Other Health Professional Japan
Primary
Concomitant
Mediastinitis Hospitalization 3/14/2011 75 Female 82 lb 5/31/2011 Physician Japan
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 5/1/2010 64 Female 110 lb 5/31/2011 Other Health Professional Japan
Primary
Concomitant
Patella Fracture Hospitalization 12/16/2009 64 Female 82 lb 6/3/2011 Physician Japan
Primary
Concomitant
Blood Triglycerides Increased Hospitalization 4/7/2011 61 Male 126 lb 6/3/2011 Physician Japan
Primary
Concomitant
Gastric Cancer Death Male 6/6/2011 Other Health Professional Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 1/1/2009 10 Male 6/10/2011 Physician Japan
Primary
Secondary
Concomitant
Subcutaneous Abscess Hospitalization 3/14/2011 75 Female 82 lb 6/16/2011 Physician Japan
Primary
Secondary
Concomitant
Gastric Cancer Death 4/24/2011 74 Male 95 lb 6/16/2011 Other Health Professional Japan
Primary
Concomitant
Infusion Related Reaction Hospitalization 12/4/2009 65 Male 150 lb 6/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 6/26/2010 77 Female 101 lb 6/27/2011 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 6/26/2010 77 Female 101 lb 7/5/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 3/20/2011 66 Female 126 lb 7/5/2011 Other Health Professional Japan
Primary
Concomitant
Malignant Ascites Death 11/24/2010 73 Male 95 lb 7/5/2011 Physician Japan
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 1/1/2011 58 Female 7/8/2011 Other Health Professional Japan
Primary
Concomitant
Gastric Cancer Hospitalization 1/5/2011 61 Male 126 lb 7/8/2011 Other Health Professional Japan
Primary
Concomitant
Pneumonitis Other Serious 9/14/2010 66 Male 126 lb 7/18/2011 Physician Japan
Primary
Secondary
Skin Ulcer Hospitalization 5/1/2010 64 Female 110 lb 8/5/2011 Other Health Professional Japan
Primary
Concomitant
Skin Ulcer Other Serious 3/20/2011 66 Female 126 lb 8/8/2011 Other Health Professional Japan
Primary
Concomitant
Nausea Hospitalization 6/5/2011 67 Male 99 lb 8/10/2011 Physician Japan
Primary
Concomitant
Diarrhoea Hospitalization 7/12/2011 3 Female 29 lb 8/12/2011 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 11/4/2010 60 Female 101 lb 8/15/2011 Other Health Professional Japan
Primary
Concomitant
Skin Infection Other Serious 3/20/2011 66 Female 126 lb 8/17/2011 Physician Japan
Primary
Concomitant
Skin Ulcer Hospitalization 5/1/2010 64 Female 110 lb 8/18/2011 Other Health Professional Japan
Primary
Concomitant
Haematochezia Other Serious 7/8/2010 51 Female 108 lb 8/26/2011 Physician Japan
Primary
Concomitant
Biliary Cirrhosis Primary Hospitalization 10/13/2010 64 Female 126 lb 8/29/2011 Other Health Professional Japan
Primary
Concomitant
Pancreatitis Acute Hospitalization 2/16/2011 63 Female 99 lb 9/2/2011 Other Health Professional Japan
Primary
Concomitant
Arthritis Hospitalization 7/12/2011 3 Female 29 lb 9/2/2011 Other Health Professional Japan
Primary
Concomitant
Ulna Fracture Hospitalization 2/18/2010 58 Female 119 lb 9/12/2011 Other Health Professional Japan
Primary
Concomitant
Blood Blister Other Serious 5/1/2010 64 Female 110 lb 9/12/2011 Other Health Professional Japan
Primary
Concomitant
Gastroenteritis Hospitalization 7/12/2011 3 Female 29 lb 9/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Other Serious 12/13/2010 50 Female 9/30/2011 Japan
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 10/19/2010 77 Female 10/11/2011 Japan
Primary
Concomitant
Diverticulum Intestinal Haemorrhagic Hospitalization 6/22/2011 61 Female 10/13/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 12/16/2009 64 Female 82 lb 10/18/2011 Japan
Primary
Concomitant
Shock Hospitalization Male 10/26/2011 Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious Female 10/26/2011 Physician Japan
Primary
Concomitant
Tuberculosis Hospitalization 9/16/2011 49 Female 132 lb 10/28/2011 Physician Japan
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 12/1/2010 32 Female 84 lb 11/8/2011 Physician Japan
Primary
Concomitant
Skin Ulcer Hospitalization 5/1/2010 64 Female 110 lb 11/9/2011 Physician Japan
Primary
Concomitant
Abdominal Pain Hospitalization 8/1/2009 63 Male 11/11/2011 Physician Japan
Primary
Concomitant
Anaemia Hospitalization 1/1/2011 60 Female 101 lb 11/14/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Death 2/6/2009 82 Male 11/23/2011 Japan
Primary
Concomitant
Epstein-barr Virus Infection Other Serious 3/4/2008 67 Female 126 lb 11/24/2011 Physician Japan
Primary
Secondary
Concomitant
Shock Hospitalization 1/1/2010 43 Male 11/28/2011 Japan
Primary
Concomitant
Tuberculosis Hospitalization 9/16/2011 49 Female 139 lb 11/28/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 9/14/2010 66 Male 126 lb 11/30/2011 Japan
Primary
Secondary
Concomitant
Eczema Vesicular Hospitalization 8/1/2009 63 Male 12/16/2011 Physician Japan
Primary
Concomitant
Tonsillectomy Other Serious Male 12/16/2011 Japan
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 7/1/2010 53 Female 95 lb 12/21/2011 Physician Japan
Primary
Secondary
Interstitial Lung Disease Other Serious Female 12/23/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 3/25/2009 55 Female 97 lb 12/29/2011 Physician Japan
Primary
Concomitant
Subarachnoid Haemorrhage Hospitalization 12/13/2010 50 Female 12/29/2011 Japan
Primary
Concomitant
Joint Destruction Hospitalization 2/24/2011 48 Female 99 lb 12/29/2011 Physician Japan
Primary
Secondary
Concomitant
Bronchitis Other Serious 3/25/2009 55 Female 97 lb 1/2/2012 Physician Japan
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 5/26/2011 65 Female 1/12/2012 Japan
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 10/1/2011 54 Female 95 lb 1/18/2012 Physician Japan
Primary
Secondary
Pancreatitis Acute Other Serious 9/18/2011 80 Female 1/24/2012 Physician Japan
Primary
Concomitant
Bronchitis Other Serious 7/17/2008 55 Female 1/26/2012 Japan
Primary
Concomitant
Anaemia Life Threatening 1/6/2012 76 Female 84 lb 2/6/2012 Physician Japan
Primary
Secondary
Concomitant
Bronchitis Other Serious 7/17/2008 55 Female 2/8/2012 Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 3/7/2011 53 Male 2/10/2012 Japan
Primary
Concomitant
Sepsis Hospitalization 1/10/2012 62 Female 2/14/2012 Physician Japan
Primary
Concomitant
Haematoma Hospitalization 1/23/2011 38 Female 2/15/2012 Physician Japan
Primary
Concomitant
Hyperlipidaemia Hospitalization 8/24/2009 62 Female 2/23/2012 Physician Japan
Primary
Secondary
Concomitant

Drug Data