Actemra combined with Loxonin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Mechanical Ileus Hospitalization 11/2/2008 Female 12/23/2008 Japan
Primary
Concomitant
Peritoneal Tuberculosis Hospitalization 11/2/2008 Female 1/8/2009 Japan
Primary
Concomitant
C-reactive Protein Increased Hospitalization 9/20/2008 Male 98 lb 1/14/2010 Physician Japan
Primary
Secondary
Concomitant
Gastric Cancer Other Serious 6/24/2009 Female 126 lb 1/21/2010 Physician Japan
Primary
Secondary
Concomitant
Gastric Cancer Other Serious 6/24/2009 Female 126 lb 1/29/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Ischaemia Death 12/6/2009 Male 123 lb 2/1/2010 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 3/18/2009 Female 105 lb 2/5/2010 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 1/20/2010 Female 99 lb 2/11/2010 Physician Japan
Primary
Secondary
Concomitant
Hyperlipidaemia Hospitalization 12/22/2008 Female 93 lb 2/25/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization Female 132 lb 3/16/2010 Physician Japan
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Other Serious 1/4/2010 Female 104 lb 3/19/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 5/15/2009 58 Female 4/15/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 5/15/2009 58 Female 4/23/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 2/28/2010 78 Female 128 lb 4/28/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 10/29/2009 68 Female 151 lb 4/28/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 5/15/2009 58 Female 106 lb 5/6/2010 Physician Japan
Primary
Concomitant
Lower Respiratory Tract Infection Life Threatening 3/1/2010 70 Male 123 lb 5/24/2010 Physician Japan
Primary
Concomitant
Arthritis Hospitalization 3/12/2010 67 Female 121 lb 6/9/2010 Physician Japan
Primary
Concomitant
Lower Respiratory Tract Infection Life Threatening 3/1/2010 70 Male 123 lb 6/10/2010 Physician Japan
Primary
Concomitant
Cerebral Infarction Disability 10/29/2009 68 Female 150 lb 6/11/2010 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 4/22/2010 62 Male 121 lb 6/25/2010 Other Health Professional Japan
Primary
Concomitant
Cardiac Failure Death 5/15/2010 55 Female 110 lb 6/28/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 4/28/2010 43 Female 110 lb 7/2/2010 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Death 5/18/2010 77 Female 75 lb 7/6/2010 Physician Japan
Primary
Concomitant
Primary Cerebellar Degeneration Other Serious 9/18/2008 67 Female 110 lb 7/9/2010 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Oticus Hospitalization 4/13/2010 67 Female 93 lb 7/15/2010 Physician Japan
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 4/28/2010 43 Female 110 lb 7/16/2010 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Death 5/18/2010 77 Female 75 lb 7/16/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Life Threatening 3/1/2010 70 Male 123 lb 7/19/2010 Physician Japan
Primary
Concomitant
Primary Cerebellar Degeneration Other Serious 9/18/2008 67 Female 110 lb 7/19/2010 Physician Japan
Primary
Secondary
Concomitant
Tonsillitis Hospitalization 6/7/2009 60 Female 7/21/2010 Physician Japan
Primary
Secondary
Concomitant
Pruritus Other Serious 1/16/2009 63 Female 130 lb 7/22/2010 Physician Japan
Primary
Secondary
Concomitant
Tonsillitis Hospitalization 9/5/2008 59 Female 7/27/2010 Physician Japan
Primary
Secondary
Concomitant
Completed Suicide Death 5/15/2010 55 Female 110 lb 7/28/2010 Physician Japan
Primary
Secondary
Concomitant
Tonsillitis Hospitalization 9/5/2008 59 Female 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
Rib Fracture Other Serious 9/18/2008 67 Female 110 lb 8/12/2010 Physician Japan
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Life Threatening 3/1/2010 70 Male 123 lb 8/16/2010 Physician Japan
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 4/28/2010 43 Female 110 lb 8/20/2010 Physician Japan
Primary
Secondary
Concomitant
Vertigo Hospitalization 2/27/2010 60 Female 132 lb 8/30/2010 Physician Japan
Primary
Concomitant
Cerebral Thrombosis Death 8/8/2010 81 Female 99 lb 8/31/2010 Physician Japan
Primary
Concomitant
Rib Fracture Other Serious 9/18/2008 67 Female 110 lb 9/1/2010 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Death 5/18/2010 77 Female 75 lb 9/7/2010 Physician Japan
Primary
Concomitant
Tonsillitis Hospitalization 9/5/2008 59 Female 9/8/2010 Physician Japan
Primary
Secondary
Concomitant
Pruritus Other Serious 1/16/2009 63 Female 130 lb 9/21/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 8/2/2010 59 Male 9/21/2010 Physician Japan
Primary
Concomitant
Tonsillitis Hospitalization 9/5/2008 59 Female 9/22/2010 Physician Japan
Primary
Secondary
Concomitant
Tension Headache Hospitalization 8/24/2010 59 Female 99 lb 10/1/2010 Physician Japan
Primary
Concomitant
Cerebral Infarction Other Serious 8/2/2010 59 Male 110 lb 10/1/2010 Physician Japan
Primary
Concomitant
Skin Cancer Life Threatening 9/20/2008 77 Male 98 lb 10/6/2010 Physician Japan
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Disability 6/7/2010 49 Female 10/7/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 3/24/2010 54 Female 119 lb 11/19/2010 Physician Japan
Primary
Secondary
Concomitant
Urticaria Life Threatening 10/10/2010 57 Female 128 lb 12/6/2010 Other Health Professional Japan
Primary
Concomitant
Portal Vein Thrombosis Hospitalization 11/10/2010 72 Female 110 lb 12/8/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 2/28/2010 78 Female 128 lb 12/14/2010 Physician Japan
Primary
Secondary
Concomitant
Urticaria Life Threatening 10/14/2010 57 Female 128 lb 12/14/2010 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 2/28/2010 78 Female 128 lb 12/20/2010 Physician Japan
Primary
Secondary
Concomitant
Skin Cancer Life Threatening 9/20/2008 77 Male 98 lb 12/23/2010 Physician Japan
Primary
Secondary
Concomitant
Portal Vein Thrombosis Other Serious 11/10/2010 72 Female 110 lb 12/27/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 10/25/2010 67 Female 12/28/2010 Physician Japan
Primary
Secondary
Concomitant
Osteoarthritis Hospitalization 6/1/2010 67 Female 12/30/2010 Physician Japan
Primary
Secondary
Concomitant
Arthritis Other Serious 12/27/2010 53 Male 112 lb 1/11/2011 Other Health Professional Japan
Primary
Concomitant
Diabetes Mellitus Other Serious 5/28/2010 54 Female 141 lb 1/19/2011 Other Health Professional Japan
Primary
Concomitant
Periarthritis Hospitalization 12/28/2010 53 Male 110 lb 1/21/2011 Physician Japan
Primary
Concomitant
Subarachnoid Haemorrhage Disability 6/7/2010 49 Female 115 lb 1/24/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 1/16/2009 63 Female 130 lb 2/1/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 6/1/2010 67 Female 2/1/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/17/2010 69 Male 154 lb 2/2/2011 Physician Japan
Primary
Concomitant
Diverticulitis Other Serious 2/15/2010 47 Male 165 lb 2/9/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Eruption Hospitalization 12/8/2010 77 Male 170 lb 2/9/2011 Physician Japan
Primary
Concomitant
Diverticulitis Other Serious 2/15/2010 47 Male 165 lb 2/11/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Eruption Hospitalization 12/8/2010 77 Male 170 lb 2/11/2011 Other Health Professional Japan
Primary
Concomitant
Pneumonia Death 9/17/2010 69 Male 154 lb 3/1/2011 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 9/17/2010 69 Male 154 lb 3/3/2011 Other Health Professional Japan
Primary
Concomitant
Hodgkin's Disease Hospitalization 5/28/2010 54 Female 141 lb 3/8/2011 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Other Serious 4/22/2010 62 Male 121 lb 3/10/2011 Other Health Professional Japan
Primary
Concomitant
Diabetes Mellitus Hospitalization 5/28/2010 54 Female 141 lb 4/13/2011 Physician Japan
Primary
Concomitant
Pulmonary Oedema Hospitalization 12/4/2009 65 Male 150 lb 4/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hodgkin's Disease Hospitalization 5/28/2010 54 Female 141 lb 4/19/2011 Physician Japan
Primary
Concomitant
Abscess Life Threatening 2/16/2011 78 Female 340 lb 4/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Endocarditis Other Serious 12/23/2010 23 Female 82 lb 4/28/2011 Physician Japan
Primary
Secondary
Concomitant
Endocarditis Other Serious 12/23/2010 23 Female 82 lb 4/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Cellulitis Other Serious 4/22/2010 62 Male 121 lb 4/29/2011 Physician Japan
Primary
Concomitant
Endophthalmitis Disability 12/16/2010 72 Female 104 lb 4/29/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 5/28/2010 54 Female 104 lb 5/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Peripheral Embolism Hospitalization 3/22/2011 52 Female 127 lb 5/13/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 3/17/2011 80 Female 110 lb 5/27/2011 Physician Japan
Primary
Secondary
Concomitant
Diverticulum Intestinal Haemorrhagic Hospitalization 4/5/2011 61 Male 150 lb 5/31/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Shock Life Threatening 10/14/2010 57 Female 128 lb 6/10/2011 Consumer Japan
Primary
Concomitant
Aortic Dissection Life Threatening 5/2/2011 75 Female 6/13/2011 Other Health Professional Japan
Primary
Concomitant
Infusion Related Reaction Hospitalization 12/4/2009 65 Male 150 lb 6/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Abscess Other Serious 1/1/2010 77 Female 340 lb 6/27/2011 Physician Japan
Primary
Secondary
Concomitant
Arthralgia Hospitalization 9/1/2010 39 Female 117 lb 7/22/2011 Physician Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 6/5/2011 67 Male 99 lb 8/10/2011 Physician Japan
Primary
Concomitant
Organising Pneumonia Hospitalization 3/5/2010 63 Female 117 lb 8/15/2011 Physician Japan
Primary
Secondary
Concomitant
Haematochezia Other Serious 7/8/2010 51 Female 108 lb 8/26/2011 Physician Japan
Primary
Concomitant
Lymphoma Life Threatening 10/20/2008 76 Male 154 lb 9/23/2011 Other Health Professional Japan
Primary
Concomitant
Organising Pneumonia Hospitalization 3/1/2010 63 Female 117 lb 9/23/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Iron Deficiency Anaemia Hospitalization 4/12/2010 60 Male 9/23/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Disorder Hospitalization 9/20/2008 77 Male 98 lb 10/7/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Hospitalization 4/12/2010 60 Male 10/14/2011 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/2/2010 54 Female 143 lb 10/17/2011 Japan
Primary
Concomitant
Vertigo Hospitalization 2/28/2010 60 Female 132 lb 10/26/2011 Physician Japan
Primary
Concomitant
Shock Hospitalization Male 10/26/2011 Japan
Primary
Concomitant
Tuberculosis Hospitalization 9/16/2011 49 Female 132 lb 10/28/2011 Physician Japan
Primary
Secondary
Concomitant
Knee Arthroplasty Other Serious 2/4/2009 71 Male 139 lb 11/8/2011 Japan
Primary
Concomitant
Colonic Polyp Hospitalization 2/3/2011 72 Female 11/8/2011 Japan
Primary
Concomitant
Ileus Hospitalization 10/27/2011 65 Female 88 lb 11/9/2011 Physician Japan
Primary
Concomitant
Pneumothorax Death 9/6/2011 71 Female 95 lb 11/10/2011 Physician Japan
Primary
Secondary
Concomitant
Viral Infection Hospitalization 12/2/2010 54 Female 143 lb 11/14/2011 Physician Japan
Primary
Concomitant
Colonic Polyp Hospitalization 2/3/2011 72 Female 11/15/2011 Japan
Primary
Concomitant
Gastric Ulcer Hospitalization 4/17/2009 76 Female 11/17/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious Male 11/24/2011 Physician Japan
Primary
Concomitant
Shock Hospitalization 1/1/2010 43 Male 11/28/2011 Japan
Primary
Concomitant
Tuberculosis Hospitalization 9/16/2011 49 Female 139 lb 11/28/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Death 4/13/2010 60 Male 11/28/2011 Physician Japan
Primary
Secondary
Concomitant
Pleurisy Other Serious 1/1/2010 70 Male 11/30/2011 Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 9/1/2011 71 Female 95 lb 12/9/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious Male 12/15/2011 Physician Japan
Primary
Concomitant
Arthritis Bacterial Life Threatening 4/17/2009 76 Female 12/20/2011 Japan
Primary
Secondary
Concomitant
Retinal Haemorrhage Hospitalization 1/18/2011 53 Female 79 lb 12/20/2011 Japan
Primary
Concomitant
Diarrhoea Life Threatening 1/1/2009 58 Female 123 lb 12/22/2011 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Life Threatening 10/31/2011 70 Male 154 lb 12/27/2011 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 11/12/2011 79 Male 121 lb 12/28/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 3/25/2009 55 Female 97 lb 12/29/2011 Physician Japan
Primary
Concomitant
Cholecystitis Acute Hospitalization 3/5/2009 64 Male 121 lb 1/2/2012 Japan
Primary
Secondary
Concomitant
Death Death 1/1/2011 80 Male 1/2/2012 Japan
Primary
Concomitant
Retinal Haemorrhage Hospitalization 1/18/2011 53 Female 79 lb 1/2/2012 Physician Japan
Primary
Concomitant
Bronchitis Other Serious 3/25/2009 55 Female 97 lb 1/2/2012 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 1/24/2011 77 Female 1/4/2012 Japan
Primary
Secondary
Concomitant
Pleurisy Hospitalization 3/3/2010 71 Male 1/4/2012 Physician Japan
Primary
Concomitant
Small Cell Lung Cancer Stage Unspecified Death 4/27/2010 66 Male 1/17/2012 Japan
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2009 56 Female 143 lb 1/18/2012 Physician Brazil
Primary
Secondary
Concomitant
Malignant Ascites Death 7/1/2011 87 Female 108 lb 1/23/2012 Physician Japan
Primary
Concomitant
Ileus Hospitalization 10/27/2011 65 Female 88 lb 1/25/2012 Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 3/7/2011 53 Male 2/10/2012 Japan
Primary
Concomitant
Gastroenteritis Hospitalization 1/25/2012 58 Female 132 lb 2/10/2012 Physician Japan
Primary
Concomitant
Haematoma Hospitalization 1/23/2011 38 Female 2/15/2012 Physician Japan
Primary
Concomitant
Gastroenteritis Hospitalization 1/25/2012 58 Female 132 lb 2/16/2012 Physician Japan
Primary
Concomitant
Gastroenteritis Norovirus Hospitalization 12/1/2011 36 Female 117 lb 2/20/2012 Physician Japan
Primary
Concomitant
Death Death 10/13/2010 80 Male 2/28/2012 Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Other Serious 1/24/2011 77 Female 3/13/2012 Japan
Primary
Secondary
Concomitant
Bronchitis Hospitalization 3/25/2009 55 Female 97 lb 3/13/2012 Japan
Primary
Concomitant
Oliguria Other Serious 10/12/2011 53 Male 95 lb 3/14/2012 Consumer Japan
Primary
Concomitant
Hepatorenal Failure Other Serious 11/10/2010 72 Female 110 lb 3/19/2012 Physician Japan
Primary
Secondary
Concomitant
Foot Amputation Hospitalization Male 3/20/2012 Physician Japan
Primary
Concomitant
Malaise Other Serious 8/20/2010 61 Female 3/26/2012 Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 1/1/2009 58 Female 123 lb 3/26/2012 Japan
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Other Serious 3/12/2012 67 Female 3/29/2012 Physician Japan
Primary
Secondary
Surgery Other Serious 1/1/2010 59 Male 3/29/2012 Japan
Primary
Concomitant
Pneumonia Bacterial Life Threatening 10/31/2011 70 Male 154 lb 4/4/2012 Physician Japan
Primary
Concomitant

Drug Data