Actemra combined with Lansoprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Erythema Multiforme Hospitalization 4/7/2010 64 Female 86 lb 5/28/2010 Physician Japan
Primary
Secondary
Erythema Multiforme Hospitalization 4/7/2010 64 Female 86 lb 7/8/2010 Physician Japan
Primary
Secondary
Bronchopulmonary Aspergillosis Death 1/1/2010 77 Female 2/7/2011 Consumer Japan
Primary
Concomitant
Interstitial Lung Disease Death 1/1/2010 77 Female 2/14/2011 Physician Japan
Primary
Secondary
Concomitant
Haemorrhage Death 1/1/2010 77 Female 2/17/2011 Physician Japan
Primary
Secondary
Concomitant
Rib Fracture Hospitalization 1/1/2010 77 Female 5/4/2011 Consumer Japan
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 5/12/2010 77 Female 78 lb 5/13/2011 Physician Japan
Primary
Concomitant
Diabetes Mellitus Hospitalization 9/3/2009 60 Male 132 lb 5/17/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Amyloidosis Death 2/22/2010 58 Female 93 lb 5/20/2011 Physician Japan
Primary
Concomitant
Aortic Aneurysm Rupture Death 12/28/2010 83 Female 5/26/2011 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 3/17/2011 80 Female 110 lb 5/27/2011 Physician Japan
Primary
Secondary
Concomitant
Patella Fracture Hospitalization 12/16/2009 64 Female 82 lb 6/3/2011 Physician Japan
Primary
Concomitant
Shock Life Threatening 10/14/2010 57 Female 128 lb 6/10/2011 Consumer Japan
Primary
Concomitant
Infusion Related Reaction Hospitalization 12/4/2009 65 Male 150 lb 6/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 1/1/2010 77 Female 7/1/2011 Consumer Japan
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 3/20/2011 66 Female 126 lb 7/5/2011 Other Health Professional Japan
Primary
Concomitant
Pneumothorax Life Threatening 1/1/2010 77 Female 7/8/2011 Consumer Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 6/23/2011 65 Male 154 lb 8/3/2011 Other Health Professional Japan
Primary
Concomitant
Skin Ulcer Other Serious 3/20/2011 66 Female 126 lb 8/8/2011 Other Health Professional Japan
Primary
Concomitant
Loss Of Consciousness Life Threatening 7/14/2011 69 Male 174 lb 8/9/2011 Pharmacist United Kingdom
Primary
Concomitant
Bradycardia Life Threatening 7/14/2011 65 Female 209 lb 8/9/2011 Pharmacist United Kingdom
Primary
Concomitant
Phlebitis Other Serious 7/13/2011 78 Female 88 lb 8/9/2011 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Amyloidosis Hospitalization 7/25/2010 71 Female 84 lb 8/15/2011 Physician Japan
Primary
Secondary
Concomitant
Bradycardia Life Threatening 7/14/2011 65 Male 212 lb 8/16/2011 Pharmacist United Kingdom
Primary
Concomitant
Pupillary Reflex Impaired Hospitalization 7/14/2011 69 Male 177 lb 8/17/2011 Other Health Professional United Kingdom
Primary
Concomitant
Skin Infection Other Serious 3/20/2011 66 Female 126 lb 8/17/2011 Physician Japan
Primary
Concomitant
Haematochezia Other Serious 7/8/2010 51 Female 108 lb 8/26/2011 Physician Japan
Primary
Concomitant
Induration 7/13/2011 78 Female 93 lb 8/26/2011 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 6/23/2011 65 Male 154 lb 9/19/2011 Pharmacist Japan
Primary
Concomitant
Implant Site Extravasation Death 12/28/2010 83 Female 9/22/2011 Other Health Professional Japan
Primary
Concomitant
Cerebrovascular Disorder Hospitalization 9/20/2008 77 Male 98 lb 10/7/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Respiratory Failure Hospitalization 7/13/2011 52 Female 10/11/2011 Other Health Professional Italy
Primary
Concomitant
Small Cell Lung Cancer Stage Unspecified Death 7/1/2009 66 Female 119 lb 10/17/2011 Physician Japan
Primary
Concomitant
Azotaemia Other Serious 12/26/2008 67 Male 10/17/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 12/16/2009 64 Female 82 lb 10/18/2011 Japan
Primary
Concomitant
Arthralgia Hospitalization 3/28/2011 53 Female 148 lb 10/20/2011 Physician Japan
Primary
Secondary
Coagulation Factor Deficiency Hospitalization 9/2/2008 47 Male 11/3/2011 Japan
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Hospitalization 7/28/2011 64 Male 183 lb 11/4/2011 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Other Serious 7/1/2011 48 Male 108 lb 11/4/2011 Physician Japan
Primary
Secondary
Concomitant
Knee Arthroplasty Other Serious 2/4/2009 71 Male 139 lb 11/8/2011 Japan
Primary
Concomitant
Skin Ulcer Hospitalization 12/1/2010 32 Female 84 lb 11/8/2011 Physician Japan
Primary
Concomitant
Polyarteritis Nodosa Hospitalization Female 11/9/2011 Japan
Primary
Concomitant
Pneumothorax Death 9/6/2011 71 Female 95 lb 11/10/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/6/2010 68 Female 11/10/2011 Physician Japan
Primary
Secondary
Concomitant
Pregnancy Other Serious 8/9/2011 38 Female 11/15/2011 Physician United States
Primary
Secondary
Concomitant
Abortion Spontaneous Other Serious 8/9/2011 38 Female 11/17/2011 United States
Primary
Secondary
Concomitant
Pleurisy Other Serious 1/1/2010 70 Male 11/30/2011 Japan
Primary
Concomitant
Gastric Cancer Other Serious 6/21/2011 72 Male 116 lb 11/30/2011 Japan
Primary
Secondary
Concomitant
Arthritis Infective Hospitalization 11/3/2011 61 Male 187 lb 12/5/2011 Physician Denmark
Primary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 6/8/2011 61 Female 101 lb 12/5/2011 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/1/2010 70 Female 86 lb 12/8/2011 Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 9/1/2011 71 Female 95 lb 12/9/2011 Physician Japan
Primary
Secondary
Concomitant
Cellulitis Other Serious 11/6/2011 60 Female 110 lb 12/20/2011 Physician Poland
Primary
Concomitant
Ovarian Neoplasm Hospitalization 12/15/2011 53 Female 119 lb 12/23/2011 Physician Japan
Primary
Secondary
Renal Impairment Other Serious 11/12/2011 79 Male 121 lb 12/28/2011 Physician Japan
Primary
Concomitant
Ovarian Neoplasm Hospitalization 12/15/2011 53 Female 119 lb 12/29/2011 Physician Japan
Primary
Secondary
Pleural Effusion Death 3/1/2010 70 Female 86 lb 1/2/2012 Physician Japan
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 5/6/2010 70 Female 1/3/2012 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/24/2011 77 Female 1/4/2012 Japan
Primary
Secondary
Concomitant
Pleurisy Hospitalization 3/3/2010 71 Male 1/4/2012 Physician Japan
Primary
Concomitant
Tendonitis Other Serious 7/7/2011 64 Male 231 lb 1/10/2012 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/21/2009 46 Female 1/12/2012 Japan
Primary
Concomitant
Gastric Cancer Death 10/12/2011 48 Female 97 lb 1/17/2012 Physician Japan
Primary
Concomitant
Ovarian Neoplasm Hospitalization 12/15/2011 53 Female 119 lb 1/17/2012 Japan
Primary
Secondary
White Blood Cell Count Increased Other Serious 60 lb 1/18/2012 Pharmacist United Kingdom
Primary
Concomitant
Gastric Cancer Death 11/9/2011 48 Female 97 lb 1/18/2012 Japan
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 4/2/2010 29 Female 1/26/2012 Japan
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 12/10/2010 46 Male 2/2/2012 Physician Japan
Primary
Secondary
Concomitant
Large Intestine Carcinoma Hospitalization 9/14/2011 68 Female 97 lb 2/2/2012 Japan
Primary
Secondary
Concomitant
Anaemia Life Threatening 1/6/2012 76 Female 84 lb 2/6/2012 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 11/21/2011 9 61 lb 2/6/2012 Pharmacist United Kingdom
Primary
Concomitant
Pleurisy Life Threatening 12/24/2011 69 Female 2/10/2012 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 3/7/2011 53 Male 2/10/2012 Japan
Primary
Concomitant
Infectious Pleural Effusion Hospitalization 9/22/2008 30 Female 88 lb 2/10/2012 Japan
Primary
Secondary
Concomitant
Haematoma Hospitalization 1/23/2011 38 Female 2/15/2012 Physician Japan
Primary
Concomitant
Subcutaneous Abscess Hospitalization 10/16/2009 67 Female 2/20/2012 Japan
Primary
Concomitant
Ovarian Cancer Hospitalization 12/15/2011 53 Female 119 lb 2/23/2012 Physician Japan
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious 1/1/2011 46 Female 128 lb 2/27/2012 Physician Japan
Primary
Secondary
Concomitant
Anaemia Life Threatening 1/6/2012 76 Female 84 lb 3/7/2012 Consumer Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 1/24/2011 77 Female 3/13/2012 Japan
Primary
Secondary
Concomitant
Large Intestine Carcinoma Hospitalization 9/14/2011 68 Female 97 lb 3/15/2012 Physician Japan
Primary
Secondary
Concomitant
Juvenile Arthritis Hospitalization 12/22/2009 10 Male 3/15/2012 Japan
Primary
Secondary
Concomitant
Cellulitis Hospitalization 8/25/2011 73 Female 93 lb 3/16/2012 Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 2/1/2011 76 Female 123 lb 3/16/2012 Physician Japan
Primary
Secondary
Concomitant
Rib Fracture Hospitalization 5/7/2009 70 Male 3/19/2012 Physician Japan
Primary
Concomitant
Malaise Other Serious 8/20/2010 61 Female 3/26/2012 Japan
Primary
Secondary
Concomitant
Bursitis Death 5/7/2009 70 Male 3/27/2012 Japan
Primary
Concomitant
Diverticulum Intestinal Life Threatening 3/19/2012 61 Female 119 lb 4/2/2012 Physician Japan
Primary
Secondary
Concomitant
Blood Uric Acid Increased Other Serious 12/26/2008 67 Male 4/6/2012 Physician Japan
Primary
Secondary
Concomitant
Gastric Cancer Hospitalization 11/9/2011 48 Female 97 lb 4/9/2012 Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 1/1/2010 61 Male 84 lb 4/11/2012 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 3/1/2012 23 Male 174 lb 4/12/2012 Other Health Professional Canada
Primary
Concomitant
Sepsis Other Serious 12/31/2011 64 Female 4/13/2012 Other Health Professional United Kingdom
Primary
Concomitant
Benign Ovarian Tumour Other Serious 7/1/2011 64 Female 103 lb 4/16/2012 Physician Japan
Primary
Secondary
Concomitant
Abscess Intestinal Hospitalization 12/27/2011 75 Female 106 lb 4/17/2012 Physician Japan
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Hospitalization 3/14/2010 54 Female 4/20/2012 Physician Japan
Primary
Concomitant
Unevaluable Event Other Serious 1/1/2012 17 Female 198 lb 5/1/2012 Canada
Primary
Concomitant
Foetal Death Death 4/1/2012 5/1/2012 Consumer Canada
Primary
Concomitant
Occult Blood Positive Hospitalization 4/11/2012 65 Female 105 lb 5/2/2012 Japan
Primary
Secondary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Death 8/11/2011 50 Male 95 lb 5/3/2012 Physician Japan
Primary
Concomitant
Benign Ovarian Tumour Other Serious 7/1/2011 64 Female 103 lb 5/7/2012 Japan
Primary
Secondary
Concomitant
Lip And/or Oral Cavity Cancer Death 3/3/2011 60 Female 5/17/2012 Japan
Primary
Secondary
Concomitant
Face Oedema Hospitalization 4/10/2012 46 Female 5/18/2012 Physician Italy
Primary
Concomitant
Occult Blood Positive Hospitalization 4/11/2012 65 Female 104 lb 5/18/2012 Physician Japan
Primary
Secondary
Concomitant
Diverticulum Hospitalization 4/12/2012 63 Female 127 lb 5/18/2012 Japan
Primary
Concomitant
Septic Shock Hospitalization 3/19/2012 61 Female 119 lb 5/21/2012 Physician Japan
Primary
Secondary
Concomitant
Inflammation Other Serious 11/6/2011 60 Female 110 lb 5/22/2012 Physician Poland
Primary
Concomitant
Femur Fracture Other Serious 10/18/2010 61 Female 84 lb 5/23/2012 Physician Japan
Primary
Concomitant
Gastric Cancer Hospitalization 2/21/2012 70 Female 101 lb 5/24/2012 Physician Japan
Primary
Secondary
Concomitant
Nausea Other Serious 1/23/2012 55 Female 84 lb 5/24/2012 Physician Japan
Primary
Concomitant
Lip And/or Oral Cavity Cancer Death 3/3/2011 60 Female 5/28/2012 Physician Japan
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization Female 5/29/2012 Other Health Professional Australia
Primary
Concomitant
Asthma Hospitalization 5/12/2012 59 Female 121 lb 6/4/2012 Physician Japan
Primary
Secondary
Concomitant
Nasopharyngitis Hospitalization 10/1/2010 38 Female 6/4/2012 Physician Japan
Primary
Concomitant
Gastric Cancer Hospitalization 2/21/2012 70 Female 101 lb 6/6/2012 Physician Japan
Primary
Secondary
Concomitant
Occult Blood Positive Hospitalization 4/11/2012 65 Female 104 lb 6/8/2012 Japan
Primary
Secondary
Concomitant
Bronchitis Hospitalization 5/12/2012 59 Female 121 lb 6/13/2012 Physician Japan
Primary
Secondary
Concomitant
Pancreatic Carcinoma Other Serious 5/10/2012 69 Male 175 lb 6/14/2012 Consumer Canada
Primary
Concomitant
Abortion Spontaneous Other Serious 8/9/2011 38 Female 6/14/2012 Physician United States
Primary
Secondary
Concomitant
Bacterial Sepsis Other Serious 1/29/2009 28 Female 117 lb 6/14/2012 Japan
Primary
Secondary
Concomitant
Large Intestine Carcinoma Hospitalization 4/11/2012 65 Female 104 lb 6/18/2012 Physician Japan
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 1/1/2010 33 Female 6/20/2012 Japan
Primary
Concomitant
Vomiting Other Serious 1/23/2012 55 Female 84 lb 6/20/2012 Physician Japan
Primary
Concomitant
Lip And/or Oral Cavity Cancer Disability 3/3/2011 60 Female 6/21/2012 Japan
Primary
Secondary
Concomitant
Impaired Healing Other Serious 1/1/2010 68 Female 126 lb 6/25/2012 Japan
Primary
Concomitant
Diarrhoea Other Serious Female 165 lb 6/27/2012 Other Health Professional United Kingdom
Primary
Concomitant
Anaemia Hospitalization 4/12/2012 63 Female 127 lb 6/29/2012 Japan
Primary
Concomitant
Scleritis Life Threatening 11/1/2011 Female 7/2/2012 Physician Japan
Primary
Concomitant
Scleritis Other Serious 11/1/2011 Female 7/3/2012 Physician Japan
Primary
Concomitant
Ascites Hospitalization 7/1/2011 64 Female 103 lb 7/5/2012 Japan
Primary
Secondary
Concomitant
Small Intestinal Obstruction Life Threatening 6/15/2012 62 Female 149 lb 7/9/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Encephalitis Autoimmune Death 7/1/2010 62 Male 141 lb 7/10/2012 Physician Japan
Primary
Concomitant
Femoral Neck Fracture Hospitalization 4/14/2011 55 Female 7/11/2012 Physician Japan
Primary
Concomitant
Tendon Rupture Other Serious 7/31/2010 34 Female 7/11/2012 Japan
Primary
Concomitant
Death Death 4/8/2012 56 Male 7/12/2012 Physician Japan
Primary
Concomitant
Nausea Other Serious 1/23/2012 55 Female 84 lb 7/12/2012 Physician Japan
Primary
Concomitant
Gastric Cancer Hospitalization 2/21/2012 70 Female 101 lb 7/17/2012 Physician Japan
Primary
Secondary
Concomitant
Oral Herpes Hospitalization 8/13/2008 66 Female 143 lb 7/25/2012 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 5/27/2012 60 Male 161 lb 8/1/2012 Physician Japan
Primary
Concomitant
Fall Hospitalization 4/14/2011 55 Female 8/3/2012 Physician Japan
Primary
Concomitant
Joint Dislocation Other Serious 3/10/2009 67 Female 110 lb 8/3/2012 Physician Japan
Primary
Secondary
Concomitant
Impaired Healing Hospitalization 1/1/2010 68 Female 126 lb 8/10/2012 Japan
Primary
Concomitant
Sepsis Other Serious 60 Male 161 lb 8/10/2012 Physician Japan
Primary
Concomitant
Pancreatic Carcinoma Other Serious 5/10/2012 69 Male 175 lb 8/17/2012 Consumer Canada
Primary
Concomitant
Abdominal Adhesions Hospitalization 6/15/2012 62 Female 149 lb 8/22/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Paralysis Hospitalization 12/27/2008 65 Female 165 lb 1/15/2013 Consumer Us
Primary
Concomitant
Septic Shock Other Serious 3/19/2012 60 Female 119 lb 10/19/2012 Physician Jp
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/26/2012 77 Female 135 lb 3/19/2013 Physician Ca
Primary
Concomitant
Stress Cardiomyopathy Hospitalization 11/7/2012 65 Female 146 lb 12/7/2012 Physician Jp
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 5/25/2012 61 Male 1/2/2013 Consumer Gb
Primary
Secondary
Concomitant

Drug Data